V. Gopalan

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Biogenesis of RNase P RNA from an intron requires co-assembly with cognate protein subunits

A. Simcox, Geeta Palsule, V. Gopalan, 2019, Nucleic acids research.

The amazing potential of fungi: 50 ways we can exploit fungi industrially

Achala R. Rathnayaka, Jianchu Xu, R. Siva, 2019, Fungal Diversity.

An RNase P‐Based Assay for Accurate Determination of the 5′‐Deoxy‐5′‐azidoguanosine‐Modified Fraction of in Vitro‐Transcribed RNAs

V. Gopalan, Seth Lyon, Tien-Hao Chen, 2018, Chembiochem : a European journal of chemical biology.

Chance and necessity in the evolution of RNase P

A. S. Krasilnikov, V. Gopalan, N. Jarrous, 2018, RNA.

Use of chemical modification and mass spectrometry to identify substrate-contacting sites in proteinaceous RNase P, a tRNA processing enzyme

V. Wysocki, V. Gopalan, M. Kvaratskhelia, 2016, Nucleic acids research.

Cleavage of Model Substrates by Arabidopsis thaliana PRORP1 Reveals New Insights into Its Substrate Requirements

David J. Kosek, V. Gopalan, P. Biswas, 2016, PloS one.

Fidelity of tRNA 5′-maturation: a possible basis for the functional dependence of archaeal and eukaryal RNase P on multiple protein cofactors

M. Stiffler, M. Foster, Deepali Singh, 2012, Nucleic acids research.

Cooperative RNP assembly: complementary rescue of structural defects by protein and RNA subunits of archaeal RNase P.

M. Foster, V. Gopalan, Yiren Xu, 2011, Journal of molecular biology.

Discovery of a minimal form of RNase P in Pyrobaculum

James W. Brown, Patricia P. Chan, T. Lowe, 2010, Proceedings of the National Academy of Sciences.

Analysis of the functional role of conserved residues in the protein subunit of ribonuclease P from Escherichia coli.

D. Landsman, S. Altman, A. Baxevanis, 1997, Journal of molecular biology.

Purification and characterization of Rpp25, an RNA-binding protein subunit of human ribonuclease P.

S. Altman, C. Guerrier-Takada, V. Gopalan, 2002, RNA.

Use of Proteomic Analysis To Elucidate the Role of Calcium in Acetone-Butanol-Ethanol Fermentation by Clostridium beijerinckii NCIMB 8052

T. Ezeji, V. Gopalan, V. Ujor, 2012, Applied and Environmental Microbiology.

Measurement of Fructose-Asparagine Concentrations in Human and Animal Foods.

T. Metz, B. Ahmer, V. Wysocki, 2018, Journal of agricultural and food chemistry.

Kinetic analysis of the interaction of alkyl glycosides with two human beta-glucosidases.

M. Claeyssens, R. Glew, V. Gopalan, 1989, The Biochemical journal.

Transglucosylation as a probe of the mechanism of action of mammalian cytosolic beta-glucosidase.

R. Glew, V. Gopalan, D. J. Vander Jagt, 1992, The Journal of biological chemistry.

Uncovering the stoichiometry of Pyrococcus furiosus RNase P, a multi-subunit catalytic ribonucleoprotein complex, by surface-induced dissociation and ion mobility mass spectrometry.

V. Wysocki, M. Foster, V. Gopalan, 2014, Angewandte Chemie.

Screening Tagged Proteins Using Tandem Affinity-Buffer Exchange Chromatography Online with Native Mass Spectrometry

Zachary L. VanAernum, V. Wysocki, V. Gopalan, 2021 .

Exolytic hydrolysis of toxic plant glucosides by guinea pig liver cytosolic beta-glucosidase.

A. Pastuszyn, R. Glew, V. Gopalan, 1992, The Journal of biological chemistry.

The dual effects of alcohols on the kinetic properties of guinea pig liver cytosolic beta-glucosidase.

R. Glew, V. Gopalan, D. P. Libell, 1989, The Journal of biological chemistry.

Characterization of an ionic liquid-tolerant β-xylosidase from a marine-derived fungal endophyte.

Angelica O. Zabala, S. Y. Tan, V. Gopalan, 2017, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Use of 4-heptylumbelliferyl-beta-D-glucoside to identify Gaucher's disease heterozygotes.

A. Waggoner, B. Butcher, R. Glew, 1989, Clinica chimica acta; international journal of clinical chemistry.

A T7 RNA Polymerase Mutant Enhances the Yield of 5′‐Thienoguanosine‐Initiated RNAs

V. Gopalan, Seth Lyon, Seth E. Lyon, 2018, Chembiochem : a European journal of chemical biology.

Training in scientific manuscript writing

R. Glew, V. Gopalan, A. Challa, 2014 .

Salmonella-Mediated Inflammation Eliminates Competitors for Fructose-Asparagine in the Gut

J. Adkins, T. Metz, B. Ahmer, 2018, Infection and Immunity.

A metabolic intermediate of the fructose-asparagine utilization pathway inhibits growth of a Salmonella fraB mutant

B. Ahmer, V. Wysocki, V. Gopalan, 2016, Scientific Reports.

Assembly of the Complex between Archaeal RNase P Proteins RPP30 and Pop5

M. Foster, Christopher J. Bohlen, Ross C Wilson, 2011, Archaea.

Serendipitous Discovery of a Competitive Inhibitor of FraB, a Salmonella Deglycase and Drug Target

S. Lindert, B. Ahmer, V. Wysocki, 2022, Pathogens.

Salmonella FraE, an Asparaginase Homolog, Contributes to Fructose-Asparagine but Not Asparagine Utilization

B. Ahmer, V. Gopalan, E. Behrman, 2017, Journal of bacteriology.

Thermodynamics of coupled folding in the interaction of archaeal RNase P proteins RPP21 and RPP29.

M. Foster, V. Gopalan, Yiren Xu, 2012, Biochemistry.

RNAs undergo phase transitions with lower critical solution temperatures

R. Pappu, V. Gopalan, Xiangze Zeng, 2022, bioRxiv.

Glycerol supplementation of the growth medium enhances in situ detoxification of furfural by Clostridium beijerinckii during butanol fermentation

T. Ezeji, V. Gopalan, V. Ujor, 2014, Applied Microbiology and Biotechnology.

The amazing potential of fungi: 50 ways we can exploit fungi industrially

Achala R. Rathnayaka, R. Siva, J. Kumla, 2019, Fungal Diversity.

Screening marine-derived endophytic fungi for xylan-degrading enzymes

V. Gopalan, T. S. Suryanarayanan, N. Thirunavukkarasu, 2015 .

Fungal endophytes: an untapped source of biocatalysts

V. Gopalan, T. S. Suryanarayanan, N. Thirunavukkarasu, 2012, Fungal Diversity.

Continuous spectrophotometric assays for beta-glucosidases acting on the plant glucosides L-picein and prunasin.

R. Glew, V. Gopalan, L. Lai, 1992, Analytical biochemistry.

Several fungi from fire-prone forests of southern India can utilize furaldehydes

V. Gopalan, T. S. Suryanarayanan, T. S. Murali, 2014, Mycological Progress.

The Anomeric Specificity of Enzymes Which Act on Sugars

V. Gopalan, E. Behrman, 2007 .

Cholesterol and Plants

V. Gopalan, E. Behrman, 2005 .

Sugar-Phosphate Toxicities

B. Ahmer, V. Gopalan, Anice Sabag-Daigle, 2021, Microbiology and molecular biology reviews : MMBR.

Acetone production in solventogenic Clostridium species: new insights from non-enzymatic decarboxylation of acetoacetate

T. Ezeji, V. Gopalan, B. Han, 2011, Applied Microbiology and Biotechnology.

Mapping RNA-protein interactions in ribonuclease P from Escherichia coli using electron paramagnetic resonance spectroscopy.

S. Altman, H. Kühne, G. Brudvig, 1999, Biochemistry.

Integrated use of biochemical, native mass spectrometry, computational and genome-editing methods to elucidate the mechanism of a Salmonella deglycase.

S. Lindert, B. Ahmer, C. Bell, 2019, Journal of molecular biology.

Structure of Mth11/Mth Rpp29, an essential protein subunit of archaeal and eukaryotic RNase P

William P. Boomershine, M. Foster, C. McElroy, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Archaeal/Eukaryal RNase P: subunits, functions and RNA diversification

V. Gopalan, N. Jarrous, 2010, Nucleic acids research.

Unexpected diversity of RNase P, an ancient tRNA processing enzyme: Challenges and prospects

V. Gopalan, L. Kirsebom, A. Vioque, 2010, FEBS letters.

Inhibition of bacterial RNase P by aminoglycoside–arginine conjugates

V. Gopalan, A. Litovchick, M. Jovanović, 2002, FEBS letters.

Varieties of RNase P: a nomenclature problem?

S. Altman, V. Gopalan, A. Vioque, 2000, RNA.

Transcriptional Control of an Essential Ribozyme in Drosophila Reveals an Ancient Evolutionary Divide in Animals

A. Simcox, S. Manivannan, V. Gopalan, 2015, PLoS genetics.

Using an L7Ae-Tethered, Hydroxyl Radical-Mediated Footprinting Strategy to Identify and Validate Kink-Turns in RNAs.

V. Gopalan, Stella M Lai, Stella M. Lai, 2021, Methods in molecular biology.

Elucidation of structure–function relationships in Methanocaldococcus jannaschii RNase P, a multi-subunit catalytic ribonucleoprotein

V. Wysocki, Andrew S. Norris, M. Foster, 2022, Nucleic acids research.

Structural basis for impaired 5′ processing of a mutant tRNA associated with defects in neuronal homeostasis

S. Ackerman, H. Al‐Hashimi, V. Gopalan, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Evidence for recycling of external guide sequences during cleavage of bipartite substrates in vitro by reconstituted archaeal RNase P.

V. Gopalan, I-Ming Cho, S. Kazakov, 2011, Journal of molecular biology.

Use of tandem affinity-buffer exchange chromatography online with native mass spectrometry for optimizing overexpression and purification of recombinant proteins.

V. Wysocki, V. Gopalan, V. Sidharthan, 2021, Methods in enzymology.

Piece by piece: Building a ribozyme

V. Gopalan, M. Gray, 2020, The Journal of Biological Chemistry.

A Land Plant-Specific Transcription Factor Directly Enhances Transcription of a Pathogenic Noncoding RNA Template by DNA-Dependent RNA Polymerase II[OPEN]

B. Ding, Ying Wang, V. Gopalan, 2015, Plant Cell.

Computationally reconstructing cotranscriptional RNA folding from experimental data reveals rearrangement of non-native folding intermediates.

Angela M. Yu, J. Lucks, Paul M. Gasper, 2021, Molecular cell.

Ramping Recombinant Protein Expression in Bacteria.

V. Gopalan, Lien B. Lai, Blake E. Szkoda, 2020, Biochemistry.

Glycerol supplementation of the growth medium enhances in situ detoxification of furfural by Clostridium beijerinckii during butanol fermentation

T. Ezeji, V. Gopalan, V. Ujor, 2014, Applied Microbiology and Biotechnology.

A functional RNase P protein subunit of bacterial origin in some eukaryotes

V. Gopalan, Pilar Bernal-Bayard, A. Vioque, 2011, Molecular Genetics and Genomics.

Translating Endophyte Research to Applications: Prospects and Challenges

G. Ravikanth, V. Gopalan, T. S. Suryanarayanan, 2017 .

Establishing a national fungal genetic resource to enhance the bioeconomy

V. Gopalan, K. Sanyal, T. S. Suryanarayanan, 2015 .

Fungal endophytes: an untapped source of biocatalysts

V. Gopalan, T. S. Suryanarayanan, N. Thirunavukkarasu, 2012, Fungal Diversity.

Characterization of a Salmonella transcription factor-DNA complex and identification of the inducer by native mass spectrometry.

V. Wysocki, V. Gopalan, E. Behrman, 2022, Journal of molecular biology.

Preparation of uniformly labeled NMR samples in Escherichia coli under the tight control of the araBAD promoter: expression of an archaeal homolog of the RNase P Rpp29 protein.

William P. Boomershine, M. Foster, V. Gopalan, 2003, Protein expression and purification.

Trials, travails and triumphs: an account of RNA catalysis in RNase P.

V. Gopalan, W. McClain, Lien B. Lai, 2010, Journal of molecular biology.

Both kinds of RNase P in all domains of life: surprises galore

C. Daniels, V. Gopalan, Tien-Hao Chen, 2018, RNA.

Elucidation of structure-function relationships in the protein subunit of bacterial RNase P using a genetic complementation approach.

S. Altman, V. Gopalan, M. Jovanović, 2002, Nucleic acids research.

RNase P as a tool for disruption of gene expression in maize cells.

E. Grotewold, V. Gopalan, S. Rangarajan, 2004, The Biochemical journal.

Identification of Bacterial Species That Can Utilize Fructose-Asparagine

B. Ahmer, V. Wysocki, K. Wrighton, 2017, Applied and Environmental Microbiology.

Genetic Analysis of Dbp 5 p , a DExD / H-box Protein Essential for Messenger RNA Export in the Yeast Saccharomyces cerevisiae

A. Simcox, V. Gopalan, Li-Chi Hung, 2007 .

Analysis of Tagged Proteins Using Tandem Affinity-Buffer Exchange Chromatography Online with Native Mass Spectrometry.

Zachary L. VanAernum, V. Wysocki, V. Gopalan, 2021, Biochemistry.

Identification of Small-Molecule Inhibitors of the Salmonella FraB Deglycase Using a Live-Cell Assay

B. Ahmer, V. Gopalan, Anice Sabag-Daigle, 2023, Microbiology spectrum.

Biochemical Studies Provide Insights into the Necessity for Multiple Arabidopsis thaliana Protein-Only RNase P Isoenzymes.

M. Sotomayor, V. Gopalan, Tien-Hao Chen, 2019, Journal of molecular biology.

Exploring the potential of plant RNase P as a functional genomics tool.

V. Gopalan, D. Pattanayak, Lien B. Lai, 2003, Methods in molecular biology.

Mapping RNA-protein interactions in ribonuclease P from Escherichia coli using disulfide-linked EDTA-Fe.

S. Altman, V. Gopalan, R. Fox, 2000, Journal of molecular biology.

The many faces of RNA-based RNase P, an RNA-world relic.

V. Gopalan, Lien B. Lai, Walter J. Zahurancik, 2021, Trends in biochemical sciences.

The rice RNase P protein subunit Rpp30 confers broad‐spectrum resistance to fungal and bacterial pathogens

Houxiang Kang, Guo‐Liang Wang, Wende Liu, 2021, Plant biotechnology journal.

A Modified pBluescript-based vector for facile cloning and transcription of RNAs.

V. Gopalan, Lien B. Lai, Hsin-Yue Tsai, 2002, Analytical biochemistry.

Cleavage of model substrates by archaeal RNase P: role of protein cofactors in cleavage-site selection

B. Pettersson, V. Gopalan, L. Kirsebom, 2010, Nucleic acids research.

Clostridium beijerinckii NCIMB 8052 Acetone-Butanol-Ethanol Fermentation by Role of Calcium in Use of Proteomic Analysis To Elucidate the

V. Gopalan, V. Ujor, B. Han, 2012 .

Characterization of a Salmonella sugar kinase essential for the utilization of fructose-asparagine.

V. Gopalan, E. Behrman, P. Biswas, 2017, Biochemistry and cell biology = Biochimie et biologie cellulaire.

RNase P: Variations and Uses*

S. Altman, V. Gopalan, A. Vioque, 2002, The Journal of Biological Chemistry.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Matthew J. Smith, J. Côté, V. Gopalan, 2023, bioRxiv.

Dissecting functional cooperation among protein subunits in archaeal RNase P, a catalytic ribonucleoprotein complex

Dileep K. Pulukkunat, V. Gopalan, Wen-Yi Chen, 2010, Nucleic acids research.

Ribozyme-Mediated Downregulation Uncovers DNA Integrity Scanning Protein A (DisA) as a Solventogenesis Determinant in Clostridium beijerinckii

T. Ezeji, V. Gopalan, V. Ujor, 2021, Frontiers in Bioengineering and Biotechnology.

Alternative Protein Topology-Mediated Evolution of a Catalytic Ribonucleoprotein.

V. Gopalan, Lien B. Lai, Walter J. Zahurancik, 2020, Trends in biochemical sciences.

Use of Cupriavidus basilensis-aided bioabatement to enhance fermentation of acid-pretreated biomass hydrolysates by Clostridium beijerinckii

T. Ezeji, V. Gopalan, V. Ujor, 2016, Journal of Industrial Microbiology & Biotechnology.

Kinetics of coupling reactions that generate monothiophosphate disulfides: implications for modification of RNAs.

C. Wu, V. Gopalan, P. Eder, 2001, Bioconjugate chemistry.

Branched Sidechain bPNA + Reports on RNA-Loop Tertiary Interactions via Triplex Hybridization Stem Replacement at Internal Domains

V. Gopalan, D. Bong, Shiqin Miao, 2019 .

Fluorescence properties of a tryptophan residue in an aromatic core of the protein subunit of ribonuclease P from Escherichia coli.

A. Fersht, S. Altman, G. Schreiber, 1997, Journal of molecular biology.

Protein cofactors and substrate influence Mg2+-dependent structural changes in the catalytic RNA of archaeal RNase P

V. Wysocki, M. Poirier, V. Gopalan, 2021, Nucleic acids research.

Molecular modeling of the three-dimensional structure of the bacterial RNase P holoenzyme.

Eric Westhof, Venkat Gopalan, Benoît Masquida, 2003, Journal of molecular biology.

Complete Genome Sequence of Desulfurococcus fermentans, a Hyperthermophilic Cellulolytic Crenarchaeon Isolated from a Freshwater Hot Spring in Kamchatka, Russia

N. Kyrpides, T. Lowe, S. Lucas, 2012, Journal of bacteriology.

The Mammalian Cytosolic Broad-Specificity β-Glucosidase

D. Vanderjagt, R. Glew, V. Gopalan, 1993 .

Copper oxide-based cathode for direct NADPH regeneration

V. Gopalan, T. Jones, J. Kadowaki, 2021, Scientific Reports.

Sequence Analysis and Comparative Study of the Protein Subunits of Archaeal RNase P

M. Samanta, C. Daniels, V. Gopalan, 2016, Biomolecules.

Studies on Methanocaldococcus jannaschii RNase P reveal insights into the roles of RNA and protein cofactors in RNase P catalysis

Dileep K. Pulukkunat, V. Gopalan, D. Pulukkunat, 2008, Nucleic acids research.

Functional reconstitution and characterization of Pyrococcus furiosus RNase P

Dileep K. Pulukkunat, V. Gopalan, D. Pulukkunat, 2006, Proceedings of the National Academy of Sciences.

Solution structure of an archaeal RNase P binary protein complex: formation of the 30-kDa complex between Pyrococcus furiosus RPP21 and RPP29 is accompanied by coupled protein folding and highlights critical features for protein-protein and protein-RNA interactions.

M. Foster, V. Gopalan, C. Amero, 2009, Journal of molecular biology.

Archaeal RNase P: A Mosaic of Its Bacterial and Eukaryal Relatives

V. Gopalan, Wen-Yi Chen, Lien B. Lai, 2010 .

Towards reconstitution of human RNase P protein subunits with human and bacterial RNase P RNAs

S. Manivannan, V. Gopalan, Emily V. Wong, 2011 .

Insights into the catalytic mechanism of a bacterial deglycase essential for utilization of fructose‐lysine

S. Lindert, C. Bell, V. Wysocki, 2023, Protein science : a publication of the Protein Society.

A novel double kink-turn module in euryarchaeal RNase P RNAs

E. Westhof, V. Wysocki, V. Gopalan, 2017, Nucleic acids research.

The L7Ae protein binds to two kink-turns in the Pyrococcus furiosus RNase P RNA

M. Foster, V. Gopalan, Lien B. Lai, 2014, Nucleic acids research.

Ribosomal protein L7Ae is a subunit of archaeal RNase P

B. Mukhopadhyay, V. Gopalan, Dwi Susanti, 2010, Proceedings of the National Academy of Sciences.

Dileep K. Pulukkunat, M. Foster, V. Gopalan, 2009, Journal of molecular biology.

Studies on the mechanism of inhibition of bacterial ribonuclease P by aminoglycoside derivatives

V. Gopalan, E. Behrman, Jing Sun, 2007, Nucleic acids research.