J. Keelan

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Prenatal testosterone exposure is related to sexually dimorphic facial morphology in adulthood

Syed Zulqarnain Gilani, F. Shafait, A. Mian, 2015, Proceedings of the Royal Society B: Biological Sciences.

Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors.

P. Mark, B. Waddell, J. Keelan, 2011, Placenta.

Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity.

P. Mark, B. Waddell, J. Keelan, 2010, Biochimica et biophysica acta.

Cytokines of the placenta and extra-placental membranes: roles and regulation during human pregnancy and parturition.

M. Mitchell, L. Chamley, J. Keelan, 2002, Placenta.

Cytokines, prostaglandins and parturition--a review.

M. Mitchell, J. Keelan, T. Sato, 2003, Placenta.

The Not-so-Sterile Womb: Evidence That the Human Fetus Is Exposed to Bacteria Prior to Birth

M. Boyce, J. Keelan, L. Stinson, 2019, Front. Microbiol..

Profiling bacterial communities in low biomass samples: pitfalls and considerations

J. Keelan, L. Stinson, M. Payne, 2019, Microbiology Australia.

Pharmacological inhibition of inflammatory pathways for the prevention of preterm birth.

J. Keelan, 2010, Journal of reproductive immunology.

Placental enzymes and transporters: new functions and genetic polymorphisms--a workshop report.

F. Kikkawa, J. Keelan, K. Ino, 2007, Placenta.

Intracellular speciation of gold nanorods alters the conformational dynamics of genomic DNA

Tristan D. Clemons, C. Bond, Diwei Ho, 2018, Nature Nanotechnology.

Transport of lipids by ABC proteins: interactions and implications for cellular toxicity, viability and function.

J. Keelan, I. Aye, Ambika T. Singh, 2009, Chemico-biological interactions.

Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-κB.

P. Mark, B. Waddell, J. Keelan, 2012, Molecular human reproduction.

Effects of nanoparticle size and gestational age on maternal biodistribution and toxicity of gold nanoparticles in pregnant mice.

Hui Yang, Yang Liu, Guangjun Nie, 2014, Toxicology letters.

Nanoparticulate drug delivery in pregnancy: placental passage and fetal exposure.

J. Keelan, A. Malek, Vinith Menezes, 2011, Current pharmaceutical biotechnology.

Applying Precision Public Health to Prevent Preterm Birth

M. Kemp, R. Hart, J. Newnham, 2017, Front. Public Health.

Regulation of activin A, inhibin A, and follistatin production in human amnion and choriodecidual explants by inflammatory mediators.

M. Mitchell, J. Keelan, N. Groome, 2000 .

Prenatal Testosterone Associates With Blood Pressure in Young Adults

L. Beilin, M. Hickey, Trevor A. Mori, 2021, Hypertension.

Gestational age-dependent up-regulation of prostaglandin D synthase (PGDS) and production of PGDS-derived antiinflammatory prostaglandins in human placenta.

M. Mitchell, R. Romero, T. Chaiworapongsa, 2006, The Journal of clinical endocrinology and metabolism.

Epithelial Cell-Derived Neutrophil-Activating Peptide-78 Is Present in Fetal Membranes and Amniotic Fluid at Increased Concentrations with Intra-amniotic Infection and Preterm Delivery1

M. Mitchell, R. Romero, T. Chaiworapongsa, 2004, Biology of reproduction.

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), TRAIL receptors, and the soluble receptor osteoprotegerin in human gestational membranes and amniotic fluid during pregnancy and labor at term and preterm.

M. Mitchell, J. Keelan, T. Sato, 2003, The Journal of clinical endocrinology and metabolism.

Macrophage inhibitory cytokine 1 in fetal membranes and amniotic fluid from pregnancies with and without preterm labour and premature rupture of membranes.

W. D. Fairlie, M. Mitchell, R. Romero, 2003, Molecular human reproduction.

Cytokines of the placenta and extra-placental membranes: biosynthesis, secretion and roles in establishment of pregnancy in women.

M. Mitchell, L. Chamley, J. Keelan, 2002, Placenta.

Strategies to Prevent Preterm Birth

C. Pennell, R. Hart, J. Newnham, 2014, Front. Immunol..

In vitro maturation as an alternative to standard in vitro fertilization for patients diagnosed with polycystic ovaries: a comparative analysis of fresh, frozen and cumulative cycle outcomes.

R. Hart, J. Keelan, E. Nathan, 2015, Human reproduction.

The ABC transporter BCRP/ABCG2 is a placental survival factor, and its expression is reduced in idiopathic human fetal growth restriction

S. Brennecke, G. Reid, K. M. Mohankumar, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

ABC drug transporter expression and functional activity in trophoblast-like cell lines and differentiating primary trophoblast.

J. Keelan, D. Evseenko, J. Paxton, 2006, American journal of physiology. Regulatory, integrative and comparative physiology.

Activin-A stimulates, while transforming growth factor beta 1 inhibits, chorionic gonadotrophin production and aromatase activity in cultured human placental trophoblasts.

Y. Song, J. Keelan, J. France, 1996, Placenta.

Early Life Events Predict Adult Testicular Function; Data Derived From the Western Australian (Raine) Birth Cohort.

N. Skakkebaek, C. Pennell, David Handelsman, 2016, The Journal of clinical endocrinology and metabolism.

The xenobiotic transporter ABCG2 plays a novel role in differentiation of trophoblast-like BeWo cells.

J. Keelan, D. Evseenko, J. Paxton, 2007, Placenta.

Letter to the editor: "fatty acids and placental transport: insight or in vitro artifact?".

J. Keelan, 2014, American journal of physiology. Cell physiology.

Second trimester amniotic fluid cytokine concentrations, Ureaplasma sp. colonisation status and sexual activity as predictors of preterm birth in Chinese and Australian women

J. Li, D. Doherty, J. Newnham, 2014, BMC Pregnancy and Childbirth.

Insulin resistance is not due to persistently elevated serum tumor necrosis‐α levels in small for gestational age, premature, or twin children

J. Keelan, P. Hofman, W. Cutfield, 2004, Pediatric diabetes.

Cytokine abundance in placental tissues: evidence of inflammatory activation in gestational membranes with term and preterm parturition.

M. Mitchell, J. Keelan, T. Sato, 1999, American journal of obstetrics and gynecology.

The Relationship Between Pregnancy Exposure to Antidepressant and Atypical Antipsychotic Medications and Placental Weight and Birth Weight Ratio: A Retrospective Cohort Study

Y. Hauck, J. Keelan, H. Liira, 2018, Journal of clinical psychopharmacology.

3'-azido-3'-deoxythymidine (AZT) induces apoptosis and alters metabolic enzyme activity in human placenta.

M. Mitchell, J. Keelan, R. Helliwell, 2003, Toxicology and applied pharmacology.

Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny

X. Hou, J. Rivera, S. Chemtob, 2018, Scientific Reports.

In vitro activity of solithromycin and its metabolites, CEM-214 and N-acetyl-CEM-101, against 100 clinical Ureaplasma spp. isolates compared with azithromycin.

J. Keelan, M. Payne, O. B. Spiller, 2015, International journal of antimicrobial agents.

Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors.

Trevor A. Mori, E. Mas, A. Barden, 2014, Reproduction.

Effects of omega-3 and omega-6 fatty acids on human placental cytokine production.

T. Mori, E. Mas, A. Barden, 2015, Placenta.

Maternal dietary omega-3 fatty acid intake increases resolvin and protectin levels in the rat placenta

Trevor A. Mori, E. Mas, A. Barden, 2013, Journal of Lipid Research.

A highly sensitive fluorescent microplate method for the determination of UDP-glucuronosyl transferase activity in tissues and placental cell lines.

M. Mitchell, J. Keelan, J. Paxton, 2000, Drug metabolism and disposition: the biological fate of chemicals.

Study Protocol for a Randomised Controlled Trial Investigating the Effects of Maternal Prebiotic Fibre Dietary Supplementation from Mid-Pregnancy to Six Months’ Post-Partum on Child Allergic Disease Outcomes

J. Garssen, M. Jenmalm, J. Keelan, 2022, Nutrients.

Altered Placental Lactogen and Leptin Expression in Placentomes from Bovine Nuclear Transfer Pregnancies1

A. Shelling, D. Wells, B. Breier, 2004, Biology of reproduction.

Nanomolar and Micromolar Effects of 15-Deoxy-Δ12,14-prostaglandin J2 on Amnion-Derived WISH Epithelial Cells: Differential Roles of Peroxisome Proliferator-Activated Receptors γ and δ and Nuclear Factor κB

M. Mitchell, J. Keelan, R. Helliwell, 2005, Molecular Pharmacology.

prostaglandin J 2 on Amnion-Derived WISH Epithelial Cells: Differential Roles of Peroxisome Proliferator-Activated Receptors and and Nuclear Factor B

M. Mitchell, J. Keelan, R. Helliwell, 2005 .

Prostaglandin H synthase-2 and cytosolic phospholipase A2 in the hypoxic-ischemic brain: role in neuronal death or survival?

P. Gluckman, M. Dragunow, M. Mitchell, 1997, Brain research. Molecular brain research.

Independent Regulation of Apical and Basolateral Drug Transporter Expression and Function in Placental Trophoblasts by Cytokines, Steroids, and Growth Factors

J. Keelan, D. Evseenko, J. Paxton, 2007, Drug Metabolism and Disposition.

Expression of TGF-β1, TGF-β2, TGF-β3 and the Receptors TGF-βRI and TGF-βRII in Placentomes of Artificially Inseminated and Nuclear Transfer Derived Bovine Pregnancies

A. Shelling, D. Wells, J. Keelan, 2006 .

Gestational age-dependent effects of lipopolysaccharide on prostaglandin production by murine decidual caps.

M. Mitchell, J. Keelan, T. Sato, 2001, Prostaglandins, leukotrienes, and essential fatty acids.

Serum Concentrations of Human Chorionic Gonadotrophs and Immunoreactive Inhibin in Early Pregnancy and Recurrent Miscarriage: A Longitudinal Study

J. Keelan, J. France, A. Zanderigo, 1996, The Australian & New Zealand journal of obstetrics & gynaecology.

Maternal circulating adipokine profile and insulin resistance in women at high risk of developing gestational diabetes mellitus.

M. J. Ong, P. Fournier, K. Guelfi, 2017, Metabolism: clinical and experimental.

Ceramide biosynthesis and metabolism in trophoblast syncytialization

J. Keelan, A. Dharmarajan, I. Aye, 2012, Molecular and Cellular Endocrinology.

The Effects of a Ceramide Analogue, N-acetylsphingosine, on Basal and Tumor Necrosis Factor-α-Stimulated Production of Prostaglandins and Cytokines in Gestational Tissues

M. Mitchell, J. Keelan, 1998 .

Cytokine-induced coordinate expression of enzymes of prostaglandin biosynthesis and metabolism: 15-hydroxyprostaglandin dehydrogenase.

M. Mitchell, J. Keelan, S. Mesnage, 2000, Prostaglandins, leukotrienes, and essential fatty acids.

Title : Independent regulation of apical and basolateral drug transporter expression and function in placental trophoblasts by cytokines , steroids and growth factors

J. Keelan, D. Evseenko, J. Paxton, 2007 .

Effects of cytokine suppressive anti-inflammatory drugs ( CSAIDs ) on inflammatory 1 activation in ex-vivo human and ovine fetal membranes . 2 3

M. Kemp, J. Newnham, J. Keelan, 2017 .

Effects of cytokine-suppressive anti-inflammatory drugs on inflammatory activation in ex vivo human and ovine fetal membranes.

M. Kemp, J. Newnham, J. Keelan, 2014, Reproduction.

Paracrine communication modulates production of Wnt antagonists and COX1-mediated prostaglandins in a decidual-trophoblast co-culture model

J. Keelan, A. Dharmarajan, S. B. Nayeem, 2015, Molecular and Cellular Endocrinology.

Cannabinoids stimulate prostaglandin production by human gestational tissues through a tissue- and CB1-receptor-specific mechanism.

M. Mitchell, M. Glass, J. Keelan, 2008, American journal of physiology. Endocrinology and metabolism.

Expression of prostaglandin H synthase-1 and -2 in murine intrauterine and gestational tissues from mid pregnancy until term.

M. Mitchell, J. Keelan, T. Sato, 2001, Prostaglandins & other lipid mediators.

Cytosolic phospholipase A(2)and 15-hydroxyprostaglandin dehydrogenase mRNA expression in murine uterine and gestational tissues during late pregnancy.

M. Mitchell, J. Keelan, T. Sato, 2001, Prostaglandins, leukotrienes, and essential fatty acids.

Direct administration of the non-competitive interleukin-1 receptor antagonist rytvela transiently reduced intrauterine inflammation in an extremely preterm sheep model of chorioamnionitis

M. Kemp, A. Jobe, N. Yaegashi, 2021, PloS one.

Expression of Interleukin‐1β mRNA in Murine Uterine and Gestational Tissues: Relationship with Gestational Age 1

M. Mitchell, J. Keelan, T. Sato, 2001, American journal of reproductive immunology.

Androgen Concentrations in Umbilical Cord Blood and Their Association with Maternal, Fetal and Obstetric Factors

M. Hickey, P. Jacoby, A. Whitehouse, 2012, PloS one.

Relationship between umbilical cord sex hormone binding globulin, sex steroids, and age at menarche: a prospective cohort study.

R. Hart, M. Hickey, J. Keelan, 2018, Fertility and sterility.

Longitudinal effects of prenatal exposure to plastic‐derived chemicals and their metabolites on asthma and lung function from childhood into adulthood

P. Sly, R. Hart, D. Doherty, 2022, Respirology.

Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy.

M. Kemp, A. Jobe, J. Newnham, 2014, American journal of obstetrics and gynecology.

Polymyxin B Agonist Capture Therapy for Intrauterine Inflammation

M. Kemp, A. Jobe, B. Kramer, 2014, Reproductive Sciences.

Does Leptin Exhibit Cytokine‐Like Properties in Tissues of Pregnancy?

M. Mitchell, J. Keelan, E. Soh, 2000, American journal of reproductive immunology.

Anti‐inflammatory Effects of Interleukin‐4, Interleukin‐10, and Transforming Growth Factor‐β on Human Placental Cells In Vitro

M. Mitchell, J. Keelan, Timothy A. Sato, 1998, American journal of reproductive immunology.

Identification of suppressors of cytokine signaling (SOCS) proteins in human gestational tissues: differential regulation is associated with the onset of labor.

M. Mitchell, J. Keelan, M. Blumenstein, 2002, The Journal of clinical endocrinology and metabolism.

Prostanoid Stimulation of Cytokine Production in an Amnion-Derived Cell Line: Evidence of a Feed-Forward Mechanism With Implications for Term and Preterm Labor

M. Mitchell, J. Keelan, T. Sato, 2000, The Journal of the Society for Gynecologic Investigation: JSGI.

Dexamethasone differentially Regulates Prostaglandin E (PGE) production in amnion fibroblast and epithelial cells

M. Mitchell, J. Keelan, W. Hansen, 1998 .

Inhibition of 15-hydroxy prostaglandin dchydrogenasc expression and activity by cytokines in human placental trophoblasts

M. Mitchell, J. Keelan, S. Mesnage, 1998 .

Key enzymes of prostaglandin biosynthesis and metabolism. Coordinate regulation of expression by cytokines in gestational tissues: a review.

M. Mitchell, S. Skinner, J. Keelan, 1999, Prostaglandins & other lipid mediators.

Predicting preterm delivery: comparison of cervicovaginal interleukin (IL)-1beta, IL-6 and IL-8 with fetal fibronectin and cervical dilatation.

M. Mitchell, J. Keelan, L. McCowan, 2001, European journal of obstetrics, gynecology, and reproductive biology.

Comparison of the cardiometabolic profiles of adolescents conceived through ART with those of a non-ART cohort

L. Beilin, R. Hart, D. Doherty, 2022, Human reproduction.

Critical Paracrine Interactions Between TNF-α and IL-10 Regulate Lipopolysaccharide-Stimulated Human Choriodecidual Cytokine and Prostaglandin E2 Production1

M. Mitchell, J. Keelan, Timothy A. Sato, 2003, The Journal of Immunology.

Comparative Studies on the Effects of Interleukin‐4 and Interleukin‐13 on Cytokine and Prostaglandin E2 Production by Amnion‐derived WISH Cells

M. Mitchell, J. Keelan, T. Sato, 1998, American journal of reproductive immunology.

Maternal perinatal depression, circulating oxytocin levels and childhood emotional disorders at 4 years of age: The importance of psychosocial context.

Marinus H. van IJzendoorn, J. Keelan, Stuart J. Watson, 2020, Journal of psychiatric research.

Corticotropin-releasing hormone, corticotropin-releasing hormone-binding protein, and activin A in maternal serum: prediction of preterm delivery and response to glucocorticoids in women with symptoms of preterm labor.

J. Keelan, L. McCowan, N. Groome, 2000, American journal of obstetrics and gynecology.

Inflammation of the Fetal Ovine Skin Following in utero Exposure to Ureaplasma parvum

M. Kemp, A. Jobe, N. Yaegashi, 2011, Reproductive Sciences.

Paradoxical proinflammatory actions of interleukin-10 in human amnion: potential roles in term and preterm labour.

M. Mitchell, J. Keelan, K. Simpson, 2004, The Journal of clinical endocrinology and metabolism.

Placental and intra-amniotic inflammation are associated with altered fetal immune responses at birth.

J. Keelan, L. Stinson, M. Payne, 2019, Placenta.

Sex differences in umbilical cord serum levels of inhibin, testosterone, oestradiol, dehydroepiandrosterone sulphate, and sex hormone-binding globulin in human term neonates.

D. Simmons, J. Keelan, J. France, 1994, Biology of the neonate.

Labour-associated changes in the regulation of production of immunomodulators in human amnion by glucocorticoids, bacterial lipopolysaccharide and pro-inflammatory cytokines.

M. Mitchell, J. Keelan, K. Simpson, 1999, Journal of reproduction and fertility.

Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1998 by The Endocrine Society Labor-Associated Changes in Interleukin-10 Production and Its Regulation by Immunomodulators in Human

M. Mitchell, J. Keelan, K. Simpson, 2022 .

Innate inflammatory responses of human decidual cells to periodontopathic bacteria.

M. Mitchell, J. Keelan, P. Bird, 2010, American journal of obstetrics and gynecology.

Suppressors of cytokine signaling proteins in human preterm placental tissues.

M. Mitchell, J. Keelan, M. Blumenstein, 2005, Journal of molecular endocrinology.

Mental health and behavioural problems in adolescents conceived after ART.

R. Hart, D. Doherty, M. Robinson, 2022, Human reproduction.

Development of a model for functional studies of ABCG2 (breast cancer resistance protein) efflux employing a standard BeWo clone (B24).

J. Keelan, A. Crowe, 2012, Assay and drug development technologies.

Prostanoid stimulation of cytokine production in an amnion-derived cell line: evidence of a feed-forward mechanism with implications for term and preterm labor.

M. Mitchell, J. Keelan, D. Gupta, 2000 .

EDITORIAL Cytokines, Hypoxia, andPreeclampsia

J. Keelan, 2005 .

Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation.

S. Brennecke, J. Keelan, D. Evseenko, 2011, Placenta.

A radioimmunoassay for plasma dehydroepiandrosterone sulphate incorporating placental steroid sulphatase as a hydrolysing reagent.

J. Keelan, J. France, W. Jackson, 1986, Journal of Steroid Biochemistry.

Maternal Administration of Solithromycin, a New, Potent, Broad-Spectrum Fluoroketolide Antibiotic, Achieves Fetal and Intra-Amniotic Antimicrobial Protection in a Pregnant Sheep Model

M. Kemp, J. Newnham, J. Keelan, 2013, Antimicrobial Agents and Chemotherapy.

Structural and morphologic differences in human oocytes after in vitro maturation compared with standard in vitro fertilization.

R. Hart, J. Keelan, J. Ryan, 2016, Fertility and sterility.

Regulation of trophoblast migration and survival by a novel neural regeneration peptide.

J. Keelan, F. Sieg, Ambika T. Singh, 2010, Reproductive biomedicine online.

Regulation of Interleukin (IL)‐6 and IL‐8 Production in an Amnion‐derived Cell Line by Cytokines, Growth Factors, Glucocorticoids, and Phorbol Esters

M. Mitchell, J. Keelan, T. Sato, 1997, American journal of reproductive immunology.

Characterization of the amnion-derived AV3 cell line for use as a model for investigation of prostaglandin-cytokine interactions in human amnion.

M. Mitchell, S. Potter, J. Keelan, 1999, Prostaglandins, leukotrienes, and essential fatty acids.

Targeting Toll‐like receptor‐4 to tackle preterm birth and fetal inflammatory injury

K. Rice, M. Stark, J. Keelan, 2020, Clinical & translational immunology.

In vitro maturation is associated with increased early embryo arrest without impairing morphokinetic development of useable embryos progressing to blastocysts.

R. Hart, J. Keelan, J. Ryan, 2015, Human reproduction.

Asthma and allergies in offspring conceived by ART: a systematic review and meta-analysis.

R. Hart, D. Doherty, J. Keelan, 2021, Human reproduction update.

Effects of interleukin-4 on the expression and activity of prostaglandin endoperoxide H synthase-2 in amnion-derived WISH cells.

M. Mitchell, J. Keelan, T. Sato, 1998, Journal of molecular endocrinology.

Umbilical cord blood androgen levels and ASD-related phenotypes at 12 and 36 months in an enriched risk cohort study

Igor Burstyn, Irva Hertz-Picciotto, Brian K. Lee, 2017, Molecular Autism.

The Possible Impact of Antenatal Exposure to Ubiquitous Phthalates Upon Male Reproductive Function at 20 Years of Age

N. Skakkebaek, K. Main, C. Pennell, 2018, Front. Endocrinol..

Ureaplasma parvum genotype, combined vaginal colonisation with Candida albicans, and spontaneous preterm birth in an Australian cohort of pregnant women

M. Kemp, J. Newnham, R. Watts, 2016, BMC Pregnancy and Childbirth.

Expression of angiogenic and neurotrophic factors in the human amnion and choriodecidua.

M. Mitchell, J. Keelan, K. Marvin, 2002, American journal of obstetrics and gynecology.

Maternal Intravenous Treatment with either Azithromycin or Solithromycin Clears Ureaplasma parvum from the Amniotic Fluid in an Ovine Model of Intrauterine Infection

M. Kemp, A. Jobe, J. Newnham, 2014, Antimicrobial Agents and Chemotherapy.

Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep.

M. Kemp, N. Yaegashi, J. Newnham, 2011, American journal of obstetrics and gynecology.

Drug Transfer and Metabolism by the Human Placenta

J. Keelan, J. Paxton, Michael R Syme, 2004, Clinical pharmacokinetics.

Activin A exerts both pro- and anti-inflammatory effects on human term gestational tissues.

M. Mitchell, J. Keelan, R. Zhou, 2000, Placenta.

Interleukin (IL)-6 and IL-8 production by human amnion: regulation by cytokines, growth factors, glucocorticoids, phorbol esters, and bacterial lipopolysaccharide.

M D Mitchell, M. Mitchell, J. Keelan, 1997, Biology of reproduction.

Active transport across the human placenta: impact on drug efficacy and toxicity

J. Keelan, D. Evseenko, J. Paxton, 2006, Expert opinion on drug metabolism & toxicology.

Measurement of Androgen and Estrogen Concentrations in Cord Blood: Accuracy, Biological Interpretation, and Applications to Understanding Human Behavioral Development

M. Maybery, M. Hickey, A. Whitehouse, 2014, Front. Endocrinol..

Adult digit ratio (2D:4D) is not related to umbilical cord androgen or estrogen concentrations, their ratios or net bioactivity.

M. Maybery, M. Hickey, A. Whitehouse, 2015, Early human development.

Perinatal testosterone exposure and cerebral lateralisation in adult males: Evidence for the callosal hypothesis

M. Maybery, M. Hickey, A. Whitehouse, 2014, Biological Psychology.

The Relationship between Umbilical Cord Estrogens and Perinatal Characteristics

R. Hart, M. Hickey, J. Keelan, 2014, Cancer Epidemiology, Biomarkers & Prevention.

Perinatal testosterone exposure and autistic-like traits in the general population: a longitudinal pregnancy-cohort study

M. Maybery, C. Pennell, M. Sawyer, 2012, Journal of Neurodevelopmental Disorders.

Sex-specific associations between umbilical cord blood testosterone levels and language delay in early childhood.

M. Maybery, M. Sawyer, M. Hickey, 2012, Journal of Child Psychology and Psychiatry and Allied Disciplines.

Comparative regulation of inhibin, activin and human chorionic gonadotropin production by placental trophoblast cells in culture.

Y. Song, J. Keelan, J. France, 1994, Placenta.

Sphingosine-sphingosine-1-phosphate pathway regulates trophoblast differentiation and syncytialization.

J. Keelan, A. Dharmarajan, I. Aye, 2012, Reproductive biomedicine online.

Effects of gestational age and surface modification on materno-fetal transfer of nanoparticles in murine pregnancy

Hui Yang, Jeffrey A. Keelan, Yang Liu, 2012, Scientific Reports.

Intercellular Adhesion Molecule‐1 (ICAM‐1) in Cervicovaginal Fluid of Women Presenting with Preterm Labor: Predictive Value for Preterm Delivery

M. Mitchell, J. Keelan, L. McCowan, 2000, American journal of reproductive immunology.

Interleukin-4 differentially regulates prostaglandin production in amnion-derived WISH cells stimulated with pro-inflammatory cytokines and epidermal growth factor.

M. Mitchell, J. Keelan, N. Helsby, 1999, Prostaglandins, leukotrienes, and essential fatty acids.

Metabolizing enzyme localization and activities in the first trimester human placenta: the effect of maternal and gestational age, smoking and alcohol consumption.

Abby C Collier, M. Mitchell, J. Keelan, 2002, Human reproduction.

UDP-glucuronosyltransferase activity, expression and cellular localization in human placenta at term.

M. Mitchell, J. Keelan, M. Blumenstein, 2002, Biochemical pharmacology.

Session 18: Lifestyle dangers for men's fertility

N. Skakkebaek, S. Kahraman, David Handelsman, 2013 .

Comparison of Bacterial DNA Profiles in Mid-Trimester Amniotic Fluid Samples From Preterm and Term Deliveries

B. Jacobsson, J. Keelan, L. Stinson, 2020, Frontiers in Microbiology.

A Critical Review of the Bacterial Baptism Hypothesis and the Impact of Cesarean Delivery on the Infant Microbiome

J. Keelan, L. Stinson, M. Payne, 2018, Front. Med..

Planting the seed: Origins, composition, and postnatal health significance of the fetal gastrointestinal microbiota

J. Keelan, L. Stinson, M. Payne, 2017, Critical reviews in microbiology.

Vaginal microbial profiling in a preterm birth high-risk cohort using shallow shotgun metagenomics

J. Keelan, C. Christophersen, Alishum Ali, 2021, Microbiology Australia.

Decreased STAT3 in human idiopathic fetal growth restriction contributes to trophoblast dysfunction.

J. Keelan, S. Degrelle, B. Kalionis, 2015, Reproduction.

Role of Wnt signalling in early pregnancy.

F. Arfuso, J. Keelan, A. Dharmarajan, 2016, Reproduction, fertility, and development.

A Specific Bacterial DNA Signature in the Vagina of Australian Women in Mid-Pregnancy Predicts High Risk of Spontaneous Preterm Birth (The Predict1000 Study).

D. Doherty, J. Newnham, J. Keelan, 2020, American journal of obstetrics and gynecology.

Expression, localisation and activity of ATP binding cassette (ABC) family of drug transporters in human amnion membranes.

J. Keelan, D. Evseenko, J. Paxton, 2007, Placenta.

Reducing preterm birth by a statewide multifaceted program: an implementation study

M. Kemp, D. Doherty, J. Newnham, 2017, American journal of obstetrics and gynecology.

of the New Zealand Society of Endocrinology

M. Vickers, J. Keelan, J. Harding, 2014 .

Testicular function in a birth cohort of young men.

N. Skakkebaek, David Handelsman, R. Hart, 2015, Human reproduction.

The treatment of bacterial vaginosis in pregnancy with clindamycin to reduce the risk of infection‐related preterm birth: a response to the Danish Society of Obstetrics and Gynecology guideline group's clinical recommendations

J. Keelan, P. Larsson, J. S. Jørgensen, 2017, Acta obstetricia et gynecologica Scandinavica.

15-deoxy-Δ12,14-prostaglandin J2-induced apoptosis in amnion-like WISH cells

M. Mitchell, B. Nijmeijer, J. Keelan, 2001 .

Intrauterine inflammatory activation, functional progesterone withdrawal, and the timing of term and preterm birth.

J. Keelan, 2018, Journal of reproductive immunology.

A New, Potent, and Placenta-Permeable Macrolide Antibiotic, Solithromycin, for the Prevention and Treatment of Bacterial Infections in Pregnancy

M. Kemp, J. Newnham, J. Keelan, 2016, Front. Immunol..

Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation

Diwei Ho, M. House, K. Iyer, 2017, Scientific Reports.

Changes in inflammatory mediators in gingival crevicular fluid following periodontal disease treatment in pregnancy: relationship to adverse pregnancy outcome.

C. Pennell, Carol A. Wang, J. Newnham, 2015, Journal of reproductive immunology.

Placental ABC transporters, cellular toxicity and stress in pregnancy.

J. Keelan, I. Aye, 2013, Chemico-biological interactions.

Concentrations of activin A, inhibin A and follistatin in human amnion, choriodecidual and placental tissues at term and preterm.

M. Mitchell, J. Keelan, T. Sato, 1999, The Journal of endocrinology.

Placental cytokines and preeclampsia.

M. Mitchell, J. Keelan, 2007, Frontiers in bioscience : a journal and virtual library.

Cytokines, Hypoxia, and Preeclampsia

M. Mitchell, J. Keelan, 2005, The Journal of the Society for Gynecologic Investigation: JSGI.

15-Deoxy-Delta(12,14)-prostaglandin J(2), a ligand for peroxisome proliferator-activated receptor-gamma, induces apoptosis in JEG3 choriocarcinoma cells.

M. Mitchell, J. Keelan, T. Sato, 1999, Biochemical and biophysical research communications.

Hypoxia inhibits activin A production by term villous trophoblast in vitro.

M. Mitchell, J. Keelan, M. Blumenstein, 2002, Placenta.

Insulin-Like Growth Factor-I and Binding Proteins 1, 2, and 3 in Bovine Nuclear Transfer Pregnancies1

D. Wells, B. Breier, J. Keelan, 2004, Biology of reproduction.

Nanotoxicology: nanoparticles versus the placenta.

Jeffrey A. Keelan, J. Keelan, 2011, Nature nanotechnology.

Use of cDNA arrays to generate differential expression profiles for inflammatory genes in human gestational membranes delivered at term and preterm.

M D Mitchell, M. Mitchell, J. Keelan, 2002, Molecular human reproduction.

"Author reply to "Commentary on A specific bacterial DNA signature in the vagina of Australian women in midpregnancy predicts high risk of spontaneous preterm birth (the Predict1000 study)"".

D. Doherty, J. Newnham, J. Keelan, 2021, American journal of obstetrics and gynecology.

High-Resolution Melt PCR Analysis for Genotyping of Ureaplasma parvum Isolates Directly from Clinical Samples

M. Kemp, T. Tabone, J. Newnham, 2013, Journal of Clinical Microbiology.

Title) Maternal Intravenous Treatment with Either Azithromycin or Solithromycin 1 Clears Ureaplasma parvum from the Amniotic Fluid in an Ovine Model of Intrauterine 2

Masatoshi, A. Jobe, R. Watts, 2014 .

Maternal Intravenous Administration of Azithromycin Results in Significant Fetal Uptake in a Sheep Model of Second Trimester Pregnancy

M. Kemp, M. Clarke, A. Jobe, 2014, Antimicrobial Agents and Chemotherapy.

Characterization of the bacterial microbiome in first‐pass meconium using propidium monoazide (PMA) to exclude nonviable bacterial DNA

J. Keelan, L. Stinson, M. Payne, 2019, Letters in applied microbiology.

Identification and removal of contaminating microbial DNA from PCR reagents: impact on low‐biomass microbiome analyses

J. Keelan, L. Stinson, M. Payne, 2018, Letters in applied microbiology.

Drugs to Block Cytokine Signaling for the Prevention and Treatment of Inflammation-Induced Preterm Birth

J. Keelan, D. Ireland, Pearl Y. Ng, 2015, Front. Immunol..

Maternal Dietary Omega-3 Fatty Acid Supplementation Reduces Placental Oxidative Stress and Increases Fetal and Placental Growth in the Rat1

Trevor A. Mori, P. Mark, B. Waddell, 2013, Biology of reproduction.

Associations between Prenatal Exposure to Phthalates and Timing of Menarche and Growth and Adiposity into Adulthood: A Twenty-Years Birth Cohort Study

K. Main, H. Frederiksen, R. Hart, 2021, International journal of environmental research and public health.

The influence of prenatal exposure to phthalates on subsequent male growth and body composition in adolescence.

K. Main, H. Frederiksen, R. Hart, 2020, Environmental research.

Therapeutic and safety considerations of nanoparticle-mediated drug delivery in pregnancy.

Diwei Ho, K. Iyer, J. Keelan, 2015, Nanomedicine.

Human placental glucuronidation and transport of 3'azido-3'-deoxythymidine and uridine diphosphate glucuronic acid.

M. Mitchell, J. Keelan, J. Paxton, 2004, Drug metabolism and disposition: the biological fate of chemicals.

The molecular mechanisms of term and preterm labor: recent progress and clinical implications.

M. Mitchell, J. Keelan, M. Coleman, 1997, Clinical obstetrics and gynecology.

Recent advances in the prevention of preterm birth

J. Newnham, J. Keelan, 2017, F1000Research.

Inflammation and normal labor

M. Mitchell, J. Keelan, 2006 .

Regulation of cytosolic phospholipase A2 expression by cytokines in human amnion cells.

M. Mitchell, J. Keelan, N. Helsby, 1999, Placenta.

Enhanced expression of intercellular adhesion molecule-1 (ICAM-1) in amnion with term and preterm labour.

M. Mitchell, J. Keelan, T. Sato, 2000, Placenta.

Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates.

K. Main, N. Skakkebæk, C. Pennell, 2020, Environmental research.

Intra-amniotic pharmacological blockade of inflammatory signalling pathways in an ovine chorioamnionitis model.

M. Kemp, Y. Miura, J. Newnham, 2015, Molecular human reproduction.

Fetal Testosterone, Socio-Emotional Engagement and Language Development

M. Hickey, A. Whitehouse, J. Keelan, 2013 .

The impact of antenatal Bisphenol A exposure on male reproductive function at 20-22 years of age.

C. Pennell, David Handelsman, R. Hart, 2017, Reproductive biomedicine online.

The perinatal androgen to estrogen ratio and autistic-like traits in the general population: a longitudinal pregnancy cohort study

M. Maybery, M. Hickey, A. Whitehouse, 2015, Journal of Neurodevelopmental Disorders.

The perinatal androgen to estrogen ratio and autistic-like traits in the general population: a longitudinal pregnancy cohort study

M. Maybery, M. Hickey, A. Whitehouse, 2015, Journal of Neurodevelopmental Disorders.

Umbilical Cord Blood Testosterone and Childhood Internalizing and Externalizing Behavior: A Prospective Study

M. Sawyer, M. Hickey, P. Jacoby, 2013, PloS one.

The association between perinatal testosterone concentration and early vocabulary development: A prospective cohort study

M. Maybery, M. Hickey, A. Whitehouse, 2013, Biological Psychology.

Umbilical cord androgens and estrogens in relation to verbal and nonverbal abilities at age 10 in the general population

M. Maybery, M. Hickey, A. Whitehouse, 2017, PloS one.

Regulation of activin-A production by human amnion, decidua and placenta in vitro by pro-inflammatory cytokines.

M. Mitchell, J. Keelan, N. Groome, 1998, Placenta.

Maternal serum activin A is not elevated before preeclampsia in women who are at high risk.

J. Keelan, R. North, Catherine A Blackburn, 2003, American journal of obstetrics and gynecology.

The relationship between oxytocin blood concentrations and antidepressants over pregnancy and the postpartum

O. Spigset, J. Keelan, Stuart J. Watson, 2020, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

The inflammatory state of the rat placenta increases in late gestation and is further enhanced by glucocorticoids in the labyrinth zone.

J. Lewis, P. Mark, B. Waddell, 2013, Placenta.

Trans-placental passage and anti-inflammatory effects of solithromycin in the human placenta.

J. Keelan, K. Pugazhenthi, 2014, Placenta.

Nanomolar and micromolar effects of 15-deoxy- ∆ 12,14 -Prostaglandin J 2 on amnion-derived WISH epithelial cells: differential roles of PPAR- γ , – δ and NF- κ B * Molecular Fast Forward.

J. Keelan, R. Helliwell, R. Gilmour, 2005 .

Associations between Prenatal Exposure to Phthalates and Features of the Metabolic Syndrome in Males from Childhood into Adulthood

L. Beilin, R. Hart, D. Doherty, 2022, International journal of environmental research and public health.

Preclinical evaluation of drugs to block inflammation-driven preterm birth

M. Kemp, J. Newnham, J. Keelan, 2017, Innate immunity.

The influence of antenatal exposure to phthalates on subsequent female reproductive development in adolescence: a pilot study.

N. Skakkebaek, K. Main, C. Pennell, 2014, Reproduction.

Hypoxia attenuates PGE(2)but increases prostacyclin and thromboxane production in human term villous trophoblast.

M. Mitchell, J. Keelan, M. Blumenstein, 2001, Placenta.

The Maternal Serological Response to Intrauterine Ureaplasma sp. Infection and Prediction of Risk of Pre-Term Birth

J. Keelan, D. Ireland, 2014, Front. Immunol..

Characterisation of Mid-Gestation Amniotic Fluid Cytokine and Bacterial DNA Profiles in Relation to Pregnancy Outcome in a Small Australian Cohort

D. Doherty, J. Newnham, J. Keelan, 2023, Microorganisms.

Re: “Amniotic fluid from healthy term pregnancies does not harbor a detectable microbial community” (2018) 6:87, https://doi.org/10.1186/s40168-018-0475-7

J. Keelan, L. Stinson, M. Payne, 2019, Microbiome.

Comparison of Meconium DNA Extraction Methods for Use in Microbiome Studies

J. Keelan, L. Stinson, M. Payne, 2018, Front. Microbiol..

Randomised controlled trial of nebulised gentamicin in children with bronchiectasis

J. Keelan, A. Stewart, C. Byrnes, 2022, Journal of paediatrics and child health.

Re-analysis of the association between perinatal androgens and pragmatic language ability

M. Maybery, R. Hart, M. Hickey, 2014, Psychoneuroendocrinology.

Efficacy and specificity of non-steroidal anti-inflammatory drugs for the inhibition of cytokine-stimulated prostaglandin E(2) secretion by amnion-derived WISH cells.

M. Mitchell, J. Keelan, T. Sato, 2002, Prostaglandins, leukotrienes, and essential fatty acids.

The 15-Deoxy-Δ12,14-prostaglandin J2Receptor, Peroxisome Proliferator Activated Receptor-γ (PPARγ) is Expressed in Human Gestational Tissues and is Functionally Active in JEG3 Choriocarcinoma Cells

M. Mitchell, J. Keelan, K. Marvin, 2000 .

Murine exposure to gold nanoparticles during early pregnancy promotes abortion by inhibiting ectodermal differentiation

L. Du, Hui Yang, J. Keelan, 2018, Molecular medicine.

Umbilical cord blood testosterone and childhood internalizing and externalizing behavior: a prospective study.

M. Sawyer, M. Hickey, P. Jacoby, 2013, PloS one.

Serum Activin A, Inhibin A, and Follistatin Concentrations in Preeclampsia or Small for Gestational Age Pregnancies

M. Mitchell, J. Keelan, R. North, 2002, Obstetrics and gynecology.

Regulation of Activin A, Inhibin A, and Follistatin Production in Human Amnion and Choriodecidual Explants by Inflammatory Mediators

M. Mitchell, J. Keelan, N. Groome, 2000, The Journal of the Society for Gynecologic Investigation: JSGI.

Prevention of Inflammatory Activation of Human Gestational Membranes in an Ex Vivo Model Using a Pharmacological NF-κB Inhibitor1

M. Mitchell, J. Keelan, Francisca Yosaatmadja, 2009, The Journal of Immunology.

Regulation of prostaglandin production in an immortalized human myometrial cell line by cytokines and non-steroidal anti-inflammatory drugs.

M. Mitchell, J. Keelan, Timothy A. Sato, 2002, European journal of obstetrics, gynecology, and reproductive biology.

Perinatal testosterone exposure and cerebral lateralisation in adult males: Evidence for the callosal hypothesis

M. Maybery, M. Hickey, A. Whitehouse, 2014, Biological Psychology.

Sex-specific associations between umbilical cord blood testosterone levels and language delay in early childhood.

M. Maybery, M. Sawyer, M. Hickey, 2012, Journal of child psychology and psychiatry, and allied disciplines.

Role of Wnt signalling in early pregnancy.

F. Arfuso, J. Keelan, A. Dharmarajan, 2016, Reproduction, fertility, and development.

Whole blood flow cytometric analysis of Ureaplasma-stimulated monocytes from pregnant women.

Tracey F Lee-Pullen, J. Keelan, E. Nathan, 2015, Journal of reproductive immunology.

Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-κB.

P. Mark, B. Waddell, J. Keelan, 2012, Molecular human reproduction.

T cell cytokine responses to stimulation with Ureaplasma parvum in pregnancy.

Tracey F Lee-Pullen, J. Keelan, E. Nathan, 2016, Journal of reproductive immunology.

Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors.

E. Mas, A. Barden, P. Mark, 2014, Reproduction.

Murine exposure to gold nanoparticles during early pregnancy promotes abortion by inhibiting ectodermal differentiation

L. Du, Hui Yang, J. Keelan, 2018, Molecular Medicine.

Umbilical Cord Blood Testosterone and Childhood Internalizing and Externalizing Behavior: A Prospective Study

M. Sawyer, M. Hickey, P. Jacoby, 2013, PloS one.

Inflammation of the Fetal Ovine Skin Following in utero Exposure to Ureaplasma parvum

M. Kemp, A. Jobe, N. Yaegashi, 2011, Reproductive Sciences.

Vaginal microbial pro ﬁ ling in a preterm birth high-risk cohort using shallow shotgun metagenomics

J. Keelan, C. Christophersen, B. C. Alishum Ali A, 2022 .