D. Hughes

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Effects of carotenoids on human immune function

D A Hughes, D. Hughes, David A. Hughes, 1999, Proceedings of the Nutrition Society.

Dietary carotenoids and human immune function.

D. Hughes, 2001, Nutrition.

Plasma F2 isoprostanes: direct evidence of increased free radical damage during acute hyperglycemia in type 2 diabetes.

M. Sampson, M. Carrier, D. Hughes, 2002, Diabetes care.

Plant polyphenols: modifiers of immune function and risk of cardiovascular disease.

D. Hughes, 2005, Nutrition.

Absence of telomere shortening and oxidative DNA damage in the young adult offspring of women with pre-gestational type 1 diabetes

M. Sampson, H. Murphy, J. Hughes, 2009, Diabetologia.

Plasma matrix metalloproteinases, low density lipoprotein oxidisability and soluble adhesion molecules after a glucose load in Type 2 diabetes

M. Sampson, S. Astley, D. Hughes, 2004, Cardiovascular diabetology.

Monocyte matrix metalloproteinase production in Type 2 diabetes and controls – a cross sectional study

M. Sampson, D. Hughes, I. Davies, 2003, Cardiovascular Diabetology.

Plasma F 2 Isoprostanes Direct evidence of increased free radical damage during acute hyperglycemia in type 2 diabetes

M. Sampson, M. Carrier, D. Hughes, 2002 .

Chromosomal telomere attrition as a mechanism for the increased risk of epithelial cancers and senescent phenotypes in type 2 diabetes

M. Sampson, D. Hughes, Mike Sampson, 2006, Diabetologia.

Quercetin and its major metabolites selectively modulate cyclic GMP‐dependent relaxations and associated tolerance in pig isolated coronary artery

P. Kroon, D. Hughes, P. Kroon, 2010, British journal of pharmacology.

Human metabolic transformation of quercetin blocks its capacity to decrease endothelial nitric oxide synthase (eNOS) expression and endothelin-1 secretion by human endothelial cells.

P. Kroon, D. Hughes, Mark S. Winterbone, 2013, Journal of agricultural and food chemistry.

Physiologically relevant metabolites of quercetin have no effect on adhesion molecule or chemokine expression in human vascular smooth muscle cells.

P. Kroon, D. Hughes, Mark S. Winterbone, 2009, Atherosclerosis.

Comparative effects of quercetin and its predominant human metabolites on adhesion molecule expression in activated human vascular endothelial cells.

Moira A. Taylor, P. Kroon, D. Hughes, 2008, Atherosclerosis.

A comparative study of the effects of quercetin and its glucuronide and sulfate metabolites on human neutrophil function in vitro.

Moira A. Taylor, P. Kroon, D. Hughes, 2008, Biochemical pharmacology.

Monocyte telomere shortening and oxidative DNA damage in type 2 diabetes.

M. Sampson, J. Hughes, D. Hughes, 2006, Diabetes care.

n‐3 polyunsaturated fatty acid supplementation, monocyte adhesion molecule expression and pro‐inflammatory mediators in Type 2 diabetes mellitus

M. Sampson, D. Hughes, A. Sampson, 2001, Diabetic medicine : a journal of the British Diabetic Association.

Changes in phosphatidylglycerol in bronchoalveolar lavage fluids from patients with cryptogenic fibrosing alveolitis.

D. Hughes, P. Haslam, 1989, Chest.

Effect of smoking on the lipid composition of lung lining fluid and relationship between immunostimulatory lipids, inflammatory cells and foamy macrophages in extrinsic allergic alveolitis.

D. Hughes, P. Haslam, 1990, The European respiratory journal.

Effect of a β-3 agonist on food intake in two strains of rats that differ in susceptibility to obesity

D. Hughes, D. York, C. White, 2004, Physiology & Behavior.

Numerical and functional alterations in circulatory lymphocytes in cigarette smokers.

D. Hughes, P. Haslam, P. Townsend, 1985, Clinical and experimental immunology.

Effects of dietary antioxidants on the immune function of middle-aged adults

D. Hughes, David A. Hughes, 1999, Proceedings of the Nutrition Society.

Vitamins and immunocompetence.

J. Blumberg, D. Hughes, 2001, Bibliotheca nutritio et dieta.

Increased DNA oxidative susceptibility without increased plasma LDL oxidizability in Type II diabetes: effects of alpha-tocopherol supplementation.

M. Sampson, S. Astley, D. Hughes, 2001, Clinical science.

The effect of beta-carotene supplementation on the immune function of blood monocytes from healthy male nonsmokers.

P. Finglas, S. Astley, D. Hughes, 1997, The Journal of laboratory and clinical medicine.

DNA damage and susceptibility to oxidative damage in lymphocytes: effects of carotenoids in vitro and in vivo

S. Astley, R. Elliott, D. Hughes, 2004, British Journal of Nutrition.

Pro-oxidant effect of α-tocopherol in patients with Type 2 Diabetes after an oral glucose tolerance test – a randomised controlled trial

M. Sampson, J. Hughes, D. Hughes, 2007 .

Increased expression of a scavenger receptor (CD36) in monocytes from subjects with Type 2 diabetes.

M. Sampson, D. Hughes, K. Ivory, 2003, Atherosclerosis.

Significant presence of terminally differentiated T cells and altered NF-κB and I-κBα interactions in healthy ageing

D. Hughes, K. Ivory, Rebecca A. Martin, 2004, Experimental Gerontology.

Monocyte matrix and ADAM metalloproteinase expression in type 2 diabetes after aspirin therapy.

M. Sampson, D. Hughes, I. Davies, 2006, Diabetes research and clinical practice.

Effects of dietary monounsaturated fatty acids on lipoprotein concentrations, compositions, and subfraction distributions and on VLDL apolipoprotein B kinetics: dose-dependent effects on LDL.

C. Packard, J. Gill, J. Cooney, 2003, The American journal of clinical nutrition.

Review of therapeutically equivalent alternatives to short acting β2 adrenoceptor agonists delivered via chlorofluorocarbon-containing inhalers

A. Woodcock, T. Walley, D. Hughes, 1999, Thorax.

Immunoregulatory properties of pulmonary surfactant: influence of variations in the phospholipid profile.

D. Hughes, M. Wilsher, P. Haslam, 1988, Clinical and experimental immunology.

Alpha-lipoic acid modulates NF-κB activity in human monocytic cells by direct interaction with DNA

D. Hughes, Heather A. Lee, 2002, Experimental Gerontology.

Are routine iron stains on bone marrow trephine biopsy specimens necessary?

B. Bain, D. Hughes, S. Stuart-Smith, 2005, Journal of Clinical Pathology.

Vitamin D and COPD: seasonal variation is important

J. Hughes, D. Hughes, G. Bentham, 2010, Thorax.

Fish oil supplementation inhibits the expression of major histocompatibility complex class II molecules and adhesion molecules on human monocytes.

D. Hughes, I. Johnson, E. Lund, 1996, The American journal of clinical nutrition.

Response of lung epithelial cells to inflammatory stimuli following exposure to the active form of vitamin D

Andrew M. Wilson, D. Sexton, D. Hughes, 2011, Proceedings of the Nutrition Society.

Diet and the maturation of the immune system

D. Hughes, 1999 .

Induction of lymphocyte proliferation by antigen‐pulsed human neutrophils

D. Hughes, P. Haslam, P. Townsend, 1992, Clinical and experimental immunology.

Immunoregulatory properties of pulmonary surfactant: effect of lung lining fluid on proliferation of human blood lymphocytes.

D. Hughes, M. Wilsher, P. Haslam, 1988, Thorax.

of human blood lymphocytes . lung lining fluid on proliferation pulmonary surfactant : effect of Immunoregulatory properties of

D. Hughes, M. Wilsher, P. Haslam, 2022 .

Lipoprotein macroaggregates in bronchoalveolar lavage fluid from patients with diffuse interstitial lung disease: comparison with idiopathic alveolar lipoproteinosis.

C. Pantin, D. Hughes, P. Haslam, 1988, Thorax.

Cord blood telomere length, telomerase activity and inflammatory markers in pregnancies in women with diabetes or gestational diabetes

M. Sampson, H. Murphy, J. Hughes, 2010, Diabetic medicine : a journal of the British Diabetic Association.

(n-3) Polyunsaturated fatty acids modulate the expression of functionally associated molecules on human monocytes in vitro.

D. Hughes, A. Pinder, S. Southon, 1996, The Journal of nutrition.

Pulmonary surfactant composition early in development of acute lung injury after cardiopulmonary bypass: prophylactic use of surfactant therapy.

T. Evans, N. Moat, D. Hughes, 1997, International journal of experimental pathology.

Suppressor cells in asthmatic children

D. Hughes, P. Hindocha, P. Hutchins, 1982, Clinical allergy.

Numerical andfunctional alterations incirculatory lymphocytes incigarette smokers

D. Hughes, P. Haslam, P. Townsend, 1985 .

n-3 polyunsaturated fatty acids inhibit the antigen-presenting function of human monocytes.

D. Hughes, A. Pinder, David A. Hughes, 2000, The American journal of clinical nutrition.

Polyunsaturated fatty acids inhibit the antigen-presenting function of human monocytes 1 – 3

D. Hughes, A. Pinder, 2022 .

The influence of the diet on the maturation of the immune system

D. Hughes, D. A. Hughes, 1998, Allergy.

Applications of Affinity Labeling in Biomedical Sciences

D. Hughes, 2001 .

Monocyte and Neutrophil Adhesion Molecule Expression During Acute Hyperglycemia and After Antioxidant Treatment in Type 2 Diabetes and Control Patients

M. Sampson, D. Hughes, K. Ivory, 2002, Arteriosclerosis, thrombosis, and vascular biology.

Diet and Human Immune Function

D. Hughes, J. Bogden, L. Darlington, 2004, Nutrition and Health.

The morphogenesis of pigeonpox virus.

D. Hughes, J. Mcferran, D. Purcell, 1972, The Journal of general virology.

Fish oil and the immune system

D. Hughes, 1995 .

Lack of association of colonic epithelium telomere length and oxidative DNA damage in Type 2 diabetes under good metabolic control

M. Sampson, D. Hughes, Hugh Kennedy, 2008, BMC endocrine disorders.

Metalloproteinase Expression in PMA-stimulated THP-1 Cells

M. Sampson, D. Hughes, D. Edwards, 2003, Journal of Biological Chemistry.

Low density lipoprotein from patients with Type 2 diabetes increases expression of monocyte matrix metalloproteinase and ADAM metalloproteinase genes

M. Sampson, D. Hughes, N. Dozio, 2007, Cardiovascular diabetology.

Effects of lycopene and lutein supplementation on the expression of functionally associated surface molecules on blood monocytes from healthy male nonsmokers.

P. Finglas, S. Astley, D. Hughes, 2000, The Journal of infectious diseases.

Dietary antioxidants and human immune function

D. Hughes, 2000 .

Human Quercetin Conjugated Metabolites Attenuate TNF-α-induced Changes in Vasomodulatory Molecules in an HUASMCs/HUVECs Co-culture Model

P. Kroon, D. Hughes, Mark S. Winterbone, 2012, Planta Medica.

Quercetin and its principal metabolites, but not myricetin, oppose lipopolysaccharide‐induced hyporesponsiveness of the porcine isolated coronary artery

P. Kroon, D. Hughes, P. Needs, 2011, British journal of pharmacology.

Beta-carotene and lycopene, but not lutein, supplementation changes the plasma fatty acid profile of healthy male non-smokers.

D. Hughes, S. Southon, A. Wright, 1999, The Journal of laboratory and clinical medicine.

Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta.

L. Moreno, F. Perez-Vizcaino, J. Duarte, 2009, Atherosclerosis.

In vitro and in vivo effects of n-3 polyunsaturated fatty acids on human monocyte function

D. Hughes, 1998, Proceedings of the Nutrition Society.

How should stainable iron in bone marrow films be assessed?

B. Bain, D. Hughes, S. Stuart-Smith, 2004, Journal of Clinical Pathology.

Hepatic production of VLDL1 but not VLDL2 is related to insulin resistance in normoglycaemic middle-aged subjects.

C. Packard, J. Gill, J. Cooney, 2004, Atherosclerosis.

Survey for CMV in field samples of Musa spp. in southern Nigeria

D. Hughes, E. J. Ekpo, E. Ayo-John, 2008 .

D. Hughes, S. Andersen, 2012 .

Surfactant replacement therapy in late-stage adult respiratory distress syndrome

T. Evans, D. Hughes, P. Haslam, 1994, The Lancet.

Immunomodulatory effects of pulmonary surfactant on natural killer cell and antibody-dependent cytotoxicity.

D. Hughes, M. Wilsher, P. Haslam, 1988, Clinical and experimental immunology.

Military studies and nutritional immunology: undernutrition and susceptibility to illness.

K. Friedl, D. Hughes, L. Darlington, 2004 .

Pro-oxidant effect of α-tocopherol in patients with Type 2 Diabetes after an oral glucose tolerance test – a randomised controlled trial

M. Sampson, J. Hughes, D. Hughes, 2007, Cardiovascular Diabetology.

Influence of Selenium-Supplemented Torula Yeast Diets on Liver-Mediated Mutagenicity of Aflatoxin B1

L. Bjeldanes, D. Hughes, 1983 .

Significant presence of terminally differentiated T cells and altered NF-kappaB and I-kappaBalpha interactions in healthy ageing.

D. Hughes, K. Ivory, Rebecca A. Martin, 2004, Experimental gerontology.

Comparison of effects of beta-carotene and lycopene supplementation on the expression of functionally associated molecules on human monocytes.

P. Finglas, S. Astley, D. Hughes, 1997, Biochemical Society transactions.