C. Bowers

发表

Endocrine control of body composition in infancy, childhood, and puberty.

Johannes D Veldhuis, J. Lovejoy, N. Mauras, 2005, Endocrine reviews.

Estradiol supplementation enhances submaximal feed-forward drive of growth hormone (GH) secretion by recombinant human GH-releasing hormone-1,44-amide in a putatively somatostatin-withdrawn milieu.

J. Veldhuis, C. Bowers, W. Evans, 2003, The Journal of clinical endocrinology and metabolism.

Hydrogen bonding interaction of thyrotropin-releasing hormone (TRH) with transmembrane tyrosine 106 of the TRH receptor.

R. Osman, M. Gershengorn, C. Bowers, 1994, The Journal of biological chemistry.

Short‐term testosterone supplementation does not activate GH and IGF‐I production in postmenopausal women

J. Veldhuis, C. Bowers, Cacia V Soares-Welch, 2005, Clinical endocrinology.

Tripartite control of growth hormone secretion in women during controlled estradiol repletion.

J. Veldhuis, C. Bowers, L. Farhy, 2007, The Journal of clinical endocrinology and metabolism.

Short-term estradiol supplementation augments growth hormone (GH) secretory responsiveness to dose-varying GH-releasing peptide infusions in healthy postmenopausal women.

S. Anderson, J. Patrie, J. Veldhuis, 2001, The Journal of clinical endocrinology and metabolism.

Sex-steroid modulation of growth hormone (GH) secretory control

J. Veldhuis, C. Bowers, 2003, Endocrine.

Contributions of gender and systemic estradiol and testosterone concentrations to maximal secretagogue drive of burst-like growth hormone secretion in healthy middle-aged and older adults.

J. Patrie, J. Veldhuis, A. Weltman, 2004, The Journal of clinical endocrinology and metabolism.

Short-term testosterone supplementation relieves growth hormone autonegative feedback in men.

A. Iranmanesh, J. Veldhuis, A. Weltman, 2004, The Journal of clinical endocrinology and metabolism.

Estradiol supplementation in postmenopausal women doubles rebound-like release of growth hormone (GH) triggered by sequential infusion and withdrawal of somatostatin: evidence that estrogen facilitates endogenous GH-releasing hormone drive.

S. Anderson, J. Patrie, J. Veldhuis, 2004, The Journal of clinical endocrinology and metabolism.

Human GH pulsatility: An ensemble property regulated by age and gender

J. Veldhuis, C. Bowers, C. Bowers, 2003, Journal of endocrinological investigation.

Pulsatile and nocturnal growth hormone secretions in men do not require periodic declines of somatostatin.

A. Barkan, E. Dimaraki, C. Jaffe, 2003, American journal of physiology. Endocrinology and metabolism.

Sex-Steroid Hormone Modulation of the Tripeptidyl Control of the Human Somatotropic Axis

S. Anderson, J. Veldhuis, C. Bowers, 2002 .

Generation of growth hormone pulsatility in women: evidence against somatostatin withdrawal as pulse initiator.

A. Barkan, E. Dimaraki, C. Jaffe, 2001, American journal of physiology. Endocrinology and metabolism.

A paradoxical gender dissociation within the growth hormone/insulin-like growth factor I axis during protracted critical illness.

G. Van den Berghe, R. Baxter, J. Veldhuis, 2000, The Journal of clinical endocrinology and metabolism.

Reactivation of pituitary hormone release and metabolic improvement by infusion of growth hormone-releasing peptide and thyrotropin-releasing hormone in patients with protracted critical illness.

G. Van den Berghe, G. V. Berghe, S. Mohan, 1999, The Journal of clinical endocrinology and metabolism.

Neuroendocrinology of prolonged critical illness: effects of exogenous thyrotropin-releasing hormone and its combination with growth hormone secretagogues.

G. Van den Berghe, G. V. Berghe, F. de Zegher, 1998, The Journal of clinical endocrinology and metabolism.

Biological evidence that separate hypothalamic hormones release the follicle stimulating and luteinizing hormones

C. Bowers, K. Folkers, B. Currie, 1973 .

Chemistry and Biosynthesis of the Hypothalamic Releasing and Inhibiting Neurohormones

C. Bowers, J. Chang, K. Folkers, 1973 .

Stimulation of LH release in men and women by LH-releasing hormone purified from porcine hypothalami.

A. R. Midgley, A. Kastin, A. Schally, 1969, The Journal of clinical endocrinology and metabolism.

Purification of hypothalamic releasing hormones of human origin.

A. Kastin, A. Segal, A. Schally, 1970, The Journal of clinical endocrinology and metabolism.

Administration of LH-releasing hormone to selected subjects.

A. R. Midgley, A. Kastin, A. Schally, 1970, American journal of obstetrics and gynecology.

A new electrocardiographic observation in cretinism.

T. N. James, C. Bowers, T. James, 1959, The Journal of pediatrics.

Hypothalamic neurohormones regulating anterior pituitary function.

S Sawano, S. Sawano, A. Kastin, 1968, Recent progress in hormone research.

Hypothalamic LH-Releasing Hormone: Chemistry, Physiology and Effect in Humans

W. White, A. Kastin, A. Schally, 1970 .

Effect of luteinizing hormone-releasing factor (LRF) on plasma LH levels in nutria (Myocastor coypus).

S. Sawano, A. Arimura, C. Bowers, 1969, General and comparative endocrinology.

The identity of chemical and hormonal properties of the thyrotropin releasing hormone and pyroglutamyl-histidyl-proline amide.

A. Schally, C. Bowers, K. Folkers, 1969, Biochemical and biophysical research communications.

Discovery of modification of the synthetic tripeptide-sequence of the thyrotropin releasing hormone having activity.

A. Schally, C. Bowers, K. Folkers, 1969, Biochemical and biophysical research communications.

Effect of thyrotropin-releasing factor in man.

A. Schally, C. Bowers, A. Parlow, 1968, The Journal of clinical endocrinology and metabolism.

NEUROHUMORAL FUNCTIONS OF THE HYPOTHALAMUS.

A. Schally, C. Bowers, W. Locke, 1964, The American journal of the medical sciences.

Effects of α- and β-Melanocyte Stimulating Hormones and Other Peptides on the Thyroid in Mice

A. Schally, C. Bowers, T. Redding, 1964 .

IN VITRO AND IN VIVO STIMULATION OF THE RELEASE OF LUTEINIZING HORMONE.

A. Schally, C. Bowers, 1964, Endocrinology.

Isolation of gram amounts of arginine vasopressin, oxytocin, and α-MSH

A. Schally, C. Bowers, W. Carter, 1964 .

CORTICOTROPIN-RELEASING FACTOR AND OTHER HYPOTHALAMIC PEPTIDES.

A. Schally, C. Bowers, 1964, Metabolism: clinical and experimental.

PURIFICATION OF LUTEINIZING HORMONE-RELEASING FACTOR FROM BOVINE HYPOTHALAMUS.

A. Schally, C. Bowers, A. V. Schally, 1964, Endocrinology.

EFFECT OF LYSINE VASOPRESSIN DIMERS ON BLOOD PRESSURE AND SOME ENDOCRINE FUNCTIONS.

A. Schally, C. Bowers, T. Redding, 1964, The American journal of physiology.

STIMULATION OF RELEASE OF FOLLICLE-STIMULATING HORMONE BY HYPOTHALAMIC EXTRACTS IN VITRO AND IN VIVO.

A. Schally, C. Bowers, Y. Ishida, 1965, Endocrinology.

The Presence of Prolactin Inhibiting Factor (PIF) in Extracts of Beef, Sheep and Pig Hypothalami∗

A. Schally, C. Bowers, Y. Ishida, 1965, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Effect of Hypothalamic Extracts on Release of Growth Hormone in vitro ∗

A. Schally, C. Bowers, S. Steelman, 1965, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Determination of CRF activity in rats treated with Monase, dexamethasone, and morphine.

A. Schally, C. Bowers, W. Carter, 1965, The American journal of physiology.

In vivo depletion of pituitary growth hormone by hypothalamic extracts.

A. Schally, C. Bowers, A. Kuroshima, 1965, Endocrinology.

An in vivo assay for thyrotropin releasing factor.

A. Schally, C. Bowers, T. Redding, 1966, Endocrinology.

Presence of Thyrotropic Hormone-Releasing Factor (TRF) In Porcine Hypothalamus.∗

A. Schally, C. Bowers, T. Redding, 1966, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Purification of thyrotropic hormone-releasing factor from bovine hypothalamus.

A. Schally, C. Bowers, T. Redding, 1966, Endocrinology.

Purification of Growth Hormone-Releasing Factor from Beef Hypothalamus.∗

A. Schally, A. Arimura, C. Bowers, 1966, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Purification of follicle-stimulating hormone-releasing factor (FSH-RF) from bovine hypothalamus.

W. White, A. Schally, A. Arimura, 1966, Endocrinology.

Isolation of thyrotropin releasing factor (TRF) from porcine hypothalamus.

A. Schally, C. Bowers, T. Redding, 1966, Biochemical and biophysical research communications.

Inhibition by pig hypothalamic extracts of depletion of pituitary prolactin in rats following cervical stimulation.

A. Schally, A. Arimura, C. Bowers, 1966, Endocrinology.

Depletion of pituitary follicle-stimulating hormone by beef and pig hypothalamic extracts.

A. Schally, A. Arimura, C. Bowers, 1966, Endocrinology.

Effects of Hypophysectomy on Hypothalamic Obesity in CBA Mice.∗

A. Schally, C. Bowers, T. Redding, 1966, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Effect of CNS-depressants, dexamethasone and growth hormone on the response to growth hormone-releasing factor.

S. Sawano, A. Schally, A. Arimura, 1967, Endocrinology.

Effect of purified luteinizing hormone-releasing factor on plasma and pituitary LH levels in castrated, testosterone pretreated male and female rats.

A. Schally, A. Arimura, C. Bowers, 1967, Endocrinology.

Absence of growth hormone-releasing factor in the posterior pituitary lobe of the rat.

S. Sawano, A. Schally, A. Arimura, 1967, Endocrinology.

Purification and in vivo and in vitro studies with porcine luteinizing hormone-releasing factor (LRF).

W. White, A. Schally, C. Bowers, 1967, Endocrinology.

Induction of ovulation in rats by highly purified pig LH-releasing factor (LRF).

A. Schally, A. Arimura, C. Bowers, 1967, Endocrinology.

Releasing factors in human hypothalamic and neurohypophysial extracts.

S. Sawano, A. Schally, A. Arimura, 1967, The Journal of clinical endocrinology and metabolism.

Pituitary-adrenal activation in rats with hereditary hypothalamic diabetes insipidus.

A. Schally, A. Arimura, C. Bowers, 1967, Acta endocrinologica.

In vivo release of follicle-stimulating hormone following administration of hypothalamic extracts in normal, castrated, and castrated testosterone-treated rats.

A. Schally, A. Arimura, C. Bowers, 1967, Endocrinology.

Interactions of L-thyroxine or L-triiodothyronine and thyrotropin-releasing factor on the release and synthesis of thyrotropin from the anterior pituitary gland of mice.

A. Schally, C. Bowers, G. Reynolds, 1967, Endocrinology.

Absence of prolactin-release inhibiting activity in highly purified LH-releasing factor.

S. Sawano, A. Schally, A. Arimura, 1967, Endocrinology.

Effect of actinomycin D on hormones that control the release of thyrotropin from the anterior pituitary glands of mice.

K. L. Lee, A. Schally, C. Bowers, 1968, Endocrinology.

GROWTH HORMONE‐RELEASING FACTOR (GRF): PHYSIOLOGICAL AND BIOCHEMICAL STUDIES WITH GRF PREPARATIONS OF BOVINE AND PORCINE ORIGIN *

S. Sawano, A. Schally, A. Arimura, 1968, Annals of the New York Academy of Sciences.

Pituitary and Plasma Growth Hormone-Like Activity after Administration of Highly Purified Pig Growth Hormone-Releasing Factor∗

S. Sawano, A. Schally, A. Arimura, 1968, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

The 24‐Hour Effects of Glyburide and Chlorpropamide After Chronic Treatment of Type II Diabetic Patients

C. Bowers, P. Prosser, J. W. Kosola, 1985, The American journal of the medical sciences.

Isolation and properties of porcine thyrotropin-releasing hormone.

A. Schally, C. Bowers, T. Redding, 1969, The Journal of biological chemistry.

The Role of Growth Hormone Secretagogues and Ghrelin in Feeding and Body Composition

J. Veldhuis, C. Bowers, B. Laferrère, 2007 .

Growth hormone response to growth hormone-releasing peptide-2 in growth hormone-deficient Little mice

C. Bowers, C. N. Peroni, P. Bartolini, 2012, Clinics.

Postpartum hyperprolactinemia and hyporesponsiveness of growth hormone (GH) to GH-releasing peptide.

F. de Zegher, G. Van den Berghe, C. Bowers, 1998, The Journal of clinical endocrinology and metabolism.

Leptin levels in protracted critical illness: effects of growth hormone-secretagogues and thyrotropin-releasing hormone.

G. Van den Berghe, R. Baxter, R. Bouillon, 1998, The Journal of clinical endocrinology and metabolism.

Growth hormone responses during strenuous exercise: the role of GH-releasing hormone and GH-releasing peptide-2.

H. Koppeschaar, C. Bowers, W. R. de Vries, 2000, Medicine and science in sports and exercise.

Modulating Effects of Progesterone on Spontaneous Nocturnal and Ghrelin-Induced GH Secretion in Postmenopausal Women.

J. Veldhuis, F. Roelfsema, C. Bowers, 2019, The Journal of clinical endocrinology and metabolism.

Regulated recovery of pulsatile growth hormone secretion from negative feedback: a preclinical investigation.

J. Veldhuis, C. Bowers, 2011, American journal of physiology. Regulatory, integrative and comparative physiology.

Sex-steroid control of the aging somatotropic axis.

A. Iranmanesh, J. Veldhuis, J. Miles, 2005, Endocrinology and metabolism clinics of North America.

Complementary secretagogue pairs unmask prominent gender-related contrasts in mechanisms of growth hormone pulse renewal in young adults.

J. Veldhuis, J. Miles, C. Bowers, 2005, The Journal of clinical endocrinology and metabolism.

Growth hormone-releasing peptide (GHRP)

C. Bowers, C. Bowers, 1998, Cellular and Molecular Life Sciences CMLS.

Secretagogue type, sex-steroid milieu, and abdominal visceral adiposity individually determine secretagogue-stimulated cortisol secretion.

A. Iranmanesh, J. Veldhuis, C. Bowers, 2010, European journal of endocrinology.

Prolactin and thyrotropin release in man by synthetic pyroglutamyl-histidyl-prolinamide.

C. Bowers, K. Folkers, P. Hwang, 1971, Biochemical and biophysical research communications.

Synthetic thyrotropin-releasing hormone. A potent stimulator of thyrotropin secretion in man.

A. Kastin, A. Schally, J. Wilber, 1971, The New England journal of medicine.

A novel in vivo rabbit model of hypercatabolic critical illness reveals a biphasic neuroendocrine stress response.

G. Van den Berghe, J. Veldhuis, C. Bowers, 2002, Endocrinology.

Pituitary responsiveness to GH‐releasing hormone, GH‐releasing peptide‐2 and thyrotrophin‐releasing hormone in critical illness

G. Van den Berghe, F. de Zegher, R. Bouillon, 1996, Clinical endocrinology.

Short-term estradiol supplementation potentiates low-dose ghrelin action in the presence of GHRH or somatostatin in older women.

J. Veldhuis, J. Miles, C. Bowers, 2014, The Journal of clinical endocrinology and metabolism.

Differential pulsatile secretagogue control of GH secretion in healthy men.

J. Veldhuis, C. Bowers, Catalina Norman, 2013, American journal of physiology. Regulatory, integrative and comparative physiology.

Sex steroids, GHRH, somatostatin, IGF-I, and IGFBP-1 modulate ghrelin's dose-dependent drive of pulsatile GH secretion in healthy older men.

J. Veldhuis, J. Miles, C. Bowers, 2012, The Journal of clinical endocrinology and metabolism.

Gender, sex-steroid, and secretagogue-selective recovery from growth hormone-induced feedback in older women and men.

J. Veldhuis, J. Miles, C. Bowers, 2011, The Journal of clinical endocrinology and metabolism.

Aromatase and 5alpha-reductase inhibition during an exogenous testosterone clamp unveils selective sex steroid modulation of somatostatin and growth hormone secretagogue actions in healthy older men.

J. Veldhuis, J. Miles, C. Bowers, 2009, The Journal of clinical endocrinology and metabolism.

Twenty-four hour continuous ghrelin infusion augments physiologically pulsatile, nycthemeral, and entropic (feedback-regulated) modes of growth hormone secretion.

A. Iranmanesh, J. Veldhuis, C. Bowers, 2008, The Journal of clinical endocrinology and metabolism.

Ghrelin potentiates growth hormone secretion driven by putative somatostatin withdrawal and resists inhibition by human corticotropin-releasing hormone.

A. Iranmanesh, P. Carpenter, J. Veldhuis, 2006, The Journal of clinical endocrinology and metabolism.

Effects of long-term treatment with growth hormone-releasing peptide-2 in the GHRH knockout mouse.

C. Bowers, A. Parlow, R. Salvatori, 2005, American journal of physiology. Endocrinology and metabolism.

Distinctive inhibitory mechanisms of age and relative visceral adiposity on growth hormone secretion in pre- and postmenopausal women studied under a hypogonadal clamp.

D. M. Keenan, J. Veldhuis, C. Bowers, 2005, The Journal of clinical endocrinology and metabolism.

Joint mechanisms of impaired growth-hormone pulse renewal in aging men.

A. Iranmanesh, J. Veldhuis, C. Bowers, 2005, The Journal of clinical endocrinology and metabolism.

Activation of somatostatin-receptor subtype-2/-5 suppresses the mass, frequency, and irregularity of growth hormone (GH)-releasing peptide-2-stimulated GH secretion in men.

A. Iranmanesh, J. Veldhuis, C. Bowers, 2004, The Journal of clinical endocrinology and metabolism.

Atypical Growth Hormone Releasing Peptides

C. Bowers, K. Sethumadhavan, K. Veeraragavan, 1994 .

Obese Subjects Respond to the Stimulatory Effect of the Ghrelin Agonist Growth Hormone‐Releasing Peptide‐2 on Food Intake

C. Bowers, B. Laferrère, Allison B Hart, 2006, Obesity.

Estradiol potentiates ghrelin-stimulated pulsatile growth hormone secretion in postmenopausal women.

D. M. Keenan, A. Iranmanesh, J. Veldhuis, 2006, The Journal of clinical endocrinology and metabolism.

Unnatural growth hormone-releasing peptide begets natural ghrelin.

C. Bowers, 2001, The Journal of clinical endocrinology and metabolism.

Impact of estradiol supplementation on dual peptidyl drive of GH secretion in postmenopausal women.

J. Veldhuis, C. Bowers, W. Evans, 2002, The Journal of clinical endocrinology and metabolism.

Interactions of growth hormone secretagogues and growth hormone-releasing hormone/somatostatin

C. Bowers, G. Tannenbaum, 2001, Endocrine.

Acute growth hormone (GH) response to GH-releasing hexapeptide in humans is independent of endogenous GH-releasing hormone.

A. Barkan, C. Bowers, R. Friberg, 1992, The Journal of clinical endocrinology and metabolism.

Growth hormone-releasing peptide-2 stimulates GH secretion in GH-deficient patients with mutated GH-releasing hormone receptor.

C. Bowers, M. Levine, R. Salvatori, 2001, The Journal of clinical endocrinology and metabolism.

The effects of GH-releasing peptide-6 (GHRP-6) and GHRP-2 on intracellular adenosine 3',5'-monophosphate (cAMP) levels and GH secretion in ovine and rat somatotrophs.

C. Bowers, I. Clarke, C. Chen, 1996, The Journal of endocrinology.

On the actions of the growth hormone-releasing hexapeptide, GHRP.

T. Badger, C. Bowers, G. Reynolds, 1991, Endocrinology.

Growth hormone (GH)-releasing peptide stimulates GH release in normal men and acts synergistically with GH-releasing hormone.

M. Thorner, S. Pezzoli, C. Bowers, 1990, The Journal of clinical endocrinology and metabolism.

Growth hormone (GH)-releasing peptide-6 requires endogenous hypothalamic GH-releasing hormone for maximal GH stimulation.

A. Barkan, C. Jaffe, C. Bowers, 1998, The Journal of clinical endocrinology and metabolism.

Testosterone blunts feedback inhibition of growth hormone secretion by experimentally elevated insulin-like growth factor-I concentrations.

A. Iranmanesh, S. Anderson, J. Veldhuis, 2005, The Journal of clinical endocrinology and metabolism.

On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone.

F. Momany, C. Bowers, G. Reynolds, 1984, Endocrinology.

Interrelationship between the novel peptide ghrelin and somatostatin/growth hormone-releasing hormone in regulation of pulsatile growth hormone secretion.

C. Bowers, J. Epelbaum, G. Tannenbaum, 2003, Endocrinology.

One-year intranasal application of growth hormone releasing peptide-2 improves body weight and hypoglycemia in a severely emaciated anorexia nervosa patient

A. Asakawa, H. Amitani, A. Inui, 2015, Journal of cachexia, sarcopenia and muscle.

Effect of corticotropin-releasing factor, dexamethasone and actinomycin D on the release of ACTH from rat pituitaries in vivo and in vitro.

A. Schally, A. Arimura, C. Bowers, 1969, Endocrinology.

Growth Hormone‐Releasing Peptides

C. Bowers, 1999 .

Late endocrine effects of administering monosodium glutamate to neonatal rats.

C. Bowers, J. Bakke, N. Lawrence, 1978, Neuroendocrinology.

Relative effects of estrogen, age, and visceral fat on pulsatile growth hormone secretion in healthy women.

J. Veldhuis, C. Bowers, G. Reynolds, 2009, American journal of physiology. Endocrinology and metabolism.

Estimation of the size and shape of GH secretory bursts in healthy women using a physiological estradiol clamp and variable-waveform deconvolution model.

D. M. Keenan, J. Veldhuis, C. Bowers, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

Peripheral estrogen receptor-alpha selectively modulates the waveform of GH secretory bursts in healthy women.

D. M. Keenan, J. Veldhuis, C. Bowers, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

Synergy of L-arginine and GHRP-2 stimulation of growth hormone in men and women: modulation by exercise.

J. Patrie, J. Veldhuis, A. Weltman, 2000, American journal of physiology. Regulatory, integrative and comparative physiology.

Aromatized Estrogens Amplify Nocturnal Growth Hormone Secretion in Testosterone-Replaced Older Hypogonadal Men

P. Takahashi, J. Veldhuis, F. Roelfsema, 2018, The Journal of clinical endocrinology and metabolism.

Estrogen-like potentiation of ghrelin-stimulated GH secretion by fulvestrant, a putatively selective ER antagonist, in postmenopausal women.

J. Veldhuis, C. Bowers, J. Wigham, 2014, The Journal of clinical endocrinology and metabolism.

Preservation of GHRH and GH-releasing peptide-2 efficacy in young men with experimentally induced hypogonadism.

D. M. Keenan, J. Veldhuis, J. Miles, 2009, European journal of endocrinology.

Dual secretagogue drive of burst-like growth hormone secretion in postmenopausal compared with premenopausal women studied under an experimental estradiol clamp.

D. M. Keenan, J. Veldhuis, J. Miles, 2004, The Journal of clinical endocrinology and metabolism.

Tripartite neuroendocrine activation of the human growth hormone (GH) axis in women by continuous 24-hour GH-releasing peptide infusion: pulsatile, entropic, and nyctohemeral mechanisms.

J. Veldhuis, C. Bowers, W. Evans, 1999, The Journal of clinical endocrinology and metabolism.

Endogenous Estrogen Regulates Somatostatin-Induced Rebound GH Secretion in Postmenopausal Women.

P. Takahashi, J. Veldhuis, C. Bowers, 2016, The Journal of clinical endocrinology and metabolism.

Interactive regulation of postmenopausal growth hormone insulin-like growth factor axis by estrogen and growth hormone-releasing peptide-2

S. Anderson, J. Veldhuis, C. Bowers, 2007, Endocrine.

Further evidence that TRH is also a physiological regulator of PRL secretion in man.

C. Bowers, H. Friesen, K. Folkers, 1973, Biochemical and biophysical research communications.

Putative somatostatin suppression potentiates adrenocorticotropin secretion driven by ghrelin and human corticotropin-releasing hormone.

A. Iranmanesh, P. Carpenter, J. Veldhuis, 2007, The Journal of clinical endocrinology and metabolism.

Ghrelin and the Growth Hormone Neuroendocrine Axis

C. Bowers, J. Epelbaum, G. Tannenbaum, 2002 .

Growth hormone-releasing activity of growth hormone-releasing peptide-1 (a synthetic heptapeptide) in children and adolescents.

Z. Laron, C. Bowers, I. Gil-ad, 1993, Acta endocrinologica.

Growth hormone-releasing peptide-2 suppresses vascular oxidative stress in ApoE-/- mice but does not reduce atherosclerosis.

P. Delafontaine, C. Bowers, Y. Higashi, 2009, Endocrinology.

Synthesis and activities of neurotensin, and its acid and amide analogs: possible natural occurrence of [Gln4]-neurotensin.

R. Carraway, S. Leeman, C. Bowers, 1976, Proceedings of the National Academy of Sciences of the United States of America.

History to the discovery of ghrelin.

C. Bowers, 2012, Methods in enzymology.

Pharmacokinetics and pharmacodynamics of growth hormone-releasing peptide-2: a phase I study in children.

G. Kearns, C. Bowers, C. Pihoker, 1998, The Journal of clinical endocrinology and metabolism.

Diagnostic studies with intravenous and intranasal growth hormone-releasing peptide-2 in children of short stature.

T. Badger, C. Bowers, G. Reynolds, 1995, The Journal of clinical endocrinology and metabolism.

Leptin levels in protracted critical illness: effects of growth hormone-secretagogues and thyrotropin-releasing hormone.

G. Van den Berghe, G. V. Berghe, R. Baxter, 1998, The Journal of clinical endocrinology and metabolism.

Presence of growth hormone secretagogue receptor messenger ribonucleic acid in human pituitary tumors and rat GH3 cells.

R. Fahlbusch, M. Buchfelder, L. V. D. van der Ploeg, 1998, The Journal of clinical endocrinology and metabolism.

The growth hormone (GH) response to GH-releasing peptide (His-DTrp-Ala-Trp-DPhe-Lys-NH2), GH-releasing hormone, and thyrotropin-releasing hormone in acromegaly.

A. Barkan, C. Jaffe, C. Bowers, 1993, The Journal of clinical endocrinology and metabolism.

On the structure of the hypothalamic luteinizing releasing hormone. Evidence for the presence of arginine, tyrosine, and tryptophan by inactivation.

C. Bowers, K. Folkers, J. K. Chang, 1971, Biochemical and biophysical research communications.

Mechanisms of conjoint failure of the somatotropic and gonadal axes in ageing men.

A. Iranmanesh, J. Veldhuis, C. Bowers, 2002, Novartis Foundation symposium.

Testosterone supplementation in healthy older men drives GH and IGF-I secretion without potentiating peptidyl secretagogue efficacy.

D. M. Keenan, J. Veldhuis, J. Miles, 2005, European journal of endocrinology.

A study on the interaction of the thyrotropin-releasing factor and L-triiodothyronine: effects of puromycin and cycloheximide.

K. L. Lee, A. Schally, C. Bowers, 1968, Endocrinology.

Physiological role of somatostatin on growth hormone regulation in humans.

E. van Cauter, M. Vance, M. Thorner, 1990, Metabolism: clinical and experimental.

GHRP historical perspective

C. Bowers, 2000 .

GH responses to intravenous bolus infusions of GH releasing hormone and GH releasing peptide 2 separately and in combination in adult volunteers

C. Bowers, V. Peterkova, A. Tiulpakov, 1995, Clinical endocrinology.

The chromatographic microassay of cholesteryl ester fatty acids (CEFA).

C. Bowers, J. E. Muldrey, J. G. Hamilton, 1965, Analytical biochemistry.

Accelerated escape from GH autonegative feedback in midpuberty in males: evidence for time-delimited GH-induced somatostatinergic outflow in adolescent boys.

W. Clarke, A. Rogol, J. Veldhuis, 2002, The Journal of clinical endocrinology and metabolism.

Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men.

C. Bowers, C. Russell, B. Laferrère, 2005, The Journal of clinical endocrinology and metabolism.

Effects of a prolonged growth hormone (GH)-releasing peptide infusion on pulsatile GH secretion in normal men.

A. Barkan, C. Jaffe, C. Bowers, 1993, The Journal of clinical endocrinology and metabolism.

Pituitary and/or peripheral estrogen-receptor alpha regulates follicle-stimulating hormone secretion, whereas central estrogenic pathways direct growth hormone and prolactin secretion in postmenopausal women.

J. Veldhuis, J. Miles, C. Bowers, 2008, The Journal of clinical endocrinology and metabolism.

Ashley Acheson, C. Bowers, E. Terasawa, 2002, The Journal of clinical endocrinology and metabolism.

Gender Impact on the GH Response to Exercise

J. Veldhuis, A. Weltman, C. Bowers, 1999 .

GHRP-GH Secretagogues

C. Bowers, 1999 .

Growth Hormone‐Releasing Hormone and Growth Hormone‐Releasing Peptide as Potential Therapeutic Modalities

E. Cauter, M. Vance, A. Rogol, 1990, Acta paediatrica Scandinavica. Supplement.

Effects of Combined Long-Term Treatment with a Growth Hormone-Releasing Hormone Analogue and a Growth Hormone Secretagogue in the Growth Hormone-Releasing Hormone Knock Out Mouse

A. Schally, C. Bowers, A. Parlow, 2006, Neuroendocrinology.

Intracerebroventricular growth-hormone-releasing peptide-6 stimulates eating without affecting plasma growth hormone responses in rats.

C. Bowers, A. Abdoh, H. Kirgis, 1995, Life sciences.

The growth hormone-releasing activity of a synthetic hexapeptide in normal men and short statured children after oral administration.

C. Bowers, J. Frentz, D. Alster, 1992, The Journal of clinical endocrinology and metabolism.

Factors other than sex steroids modulate GHRH and GHRP-2 efficacies in men: evaluation using a GnRH agonist/testosterone clamp.

J. Veldhuis, C. Bowers, 2009, The Journal of clinical endocrinology and metabolism.

Gonadal status and body mass index jointly determine growth hormone (GH)-releasing hormone/GH-releasing peptide synergy in healthy men.

J. Veldhuis, J. Miles, C. Bowers, 2008, The Journal of clinical endocrinology and metabolism.

Postpartum hyperprolactinemia and hyporesponsiveness of growth hormone (GH) to GH-releasing peptide.

G. V. Berghe, F. de Zegher, C. Bowers, 1998, The Journal of clinical endocrinology and metabolism.

Determinants of dual secretagogue drive of burst-like growth hormone secretion in premenopausal women studied under a selective estradiol clamp.

D. M. Keenan, J. Veldhuis, C. Bowers, 2005, The Journal of clinical endocrinology and metabolism.

A new dimension on the induced release of growth hormone in obese subjects.

C. Bowers, 1993, The Journal of clinical endocrinology and metabolism.

A study on the regulation of growth hormone release from the pituitaries of rats in vitro.

F. Momany, C. Bowers, G. Reynolds, 1981, Endocrinology.

Isolation of N-acetylaspartic acid from hypothalamic tissue and significance of its ACTH-releasing activity.

C. Bowers, K. Folkers, D. Barofsky, 1978, Biochemical and biophysical research communications.

Three-peptide control of pulsatile and entropic feedback-sensitive modes of growth hormone secretion: modulation by estrogen and aromatizable androgen.

J. Veldhuis, C. Bowers, 2003, Journal of pediatric endocrinology & metabolism : JPEM.

Growth hormone (GH)-releasing heptapeptide, but not GH-releasing hormone, inhibits thyrotropin-stimulated thyroid hormone secretion and cAMP formation in cultured human thyroid follicles.

Z. Laron, C. Bowers, Z. Kraiem, 1995, European journal of endocrinology.

Growth hormone releasing peptides: physiology and clinical applications

C. Bowers, 2000 .

Effects of eight months treatment with graded doses of a growth hormone (GH)-releasing peptide in GH-deficient children.

V. Mericq, G. Iñiguez, F. Cassorla, 1998, The Journal of clinical endocrinology and metabolism.

The minute blood vessels in disease.

C. Bowers, R. H. Turner, 1955, The American journal of medicine.

Treatment effects of intranasal growth hormone releasing peptide-2 in children with short stature.

T. Badger, C. Bowers, G. Reynolds, 1997, The Journal of endocrinology.

Dose-response characteristics of various peptides with growth hormone-releasing activity in the unanesthetized male rat.

J. B. Martin, W. Millard, T. Badger, 1985, Endocrinology.

On the isolation of a prolactin inhibiting factor (hormone).

C. Bowers, T. Greibrokk, K. Folkers, 1975, Biochemical and biophysical research communications.

Effects of the enkephalins and enkephalin analogs on release of pituitary hormones in vitro

C. Bowers, 1977 .

Corticotropin releasing activity of lysine vasopressin analogues.

A. Schally, A. Arimura, C. Bowers, 1969, Endocrinology.

Evaluation of orntide microspheres in a rat animal model and correlation to in vitro release profiles

C. Bowers, G. Reynolds, J. Kostanski, 2000, AAPS PharmSciTech.

GH Releasing Peptides - Structure and Kinetics

C. Bowers, 1993, The Journal of pediatric endocrinology.

Effects of Toremifene, a Selective Estrogen Receptor Modulator, on Spontaneous and Stimulated GH Secretion, IGF-I, and IGF-Binding Proteins in Healthy Elderly Subjects

P. Takahashi, J. Veldhuis, F. Roelfsema, 2017, Journal of the Endocrine Society.

Protein kinase C-dependent growth hormone releasing peptides stimulate cyclic adenosine 3',5'-monophosphate production by human pituitary somatotropinomas expressing gsp oncogenes: evidence for crosstalk between transduction pathways.

R. Fahlbusch, M. Buchfelder, C. Bowers, 1996, Molecular endocrinology.

Hormonal therapy in cancer of the breast. XVI. The effect of Δ1‐testololactone on clinical course and hormonal excretion

C. Bowers, A. Segaloff, J. Weeth, 1960 .

Extrapigmentary effects of melanocyte-stimulating hormone in amenorrhoeic women.

D. Ingvar, C. Krakau, A. Kastin, 1968, Lancet.

Structure of porcine thyrotropin releasing hormone.

A. Schally, C. Bowers, R. Nair, 1970, Biochemistry.

Studies on the site of action of oral contraceptive steroids. II. Plasma LH and FSH levels after administration of antifertility steroids and LH-releasing hormone(LH-RH).

A. Schally, A. Arimura, C. Bowers, 1970, Endocrinology.

Topochemically related hormone structures. Synthesis of partial retro-inverso analogs of LH-RH.

C. Bowers, M. Goodman, N. Chaturvedi, 2009, International journal of peptide and protein research.

New, highly active antagonists of LHRH with acylated lysine and p-aminophenylalanine in positions 5 and 6.

A. Janecka, C. Bowers, K. Folkers, 2009, International journal of peptide and protein research.

Novel, potent luteinizing hormone-releasing hormone antagonists with improved solubility in water.

A. Janecka, C. Bowers, K. Folkers, 1994, Journal of medicinal chemistry.

A new pituitary hormone.

C. Bowers, 1995, Endocrinology.

Antide B, an antagonist of LHRH with cis-3-(4-pyrazinylcarbonylaminocyclohexyl)alanine in position 5

A. Janecka, C. Bowers, K. Folkers, 1995, Amino Acids.

Superiority of an antagonist of the luteinizing hormone releasing hormone with emphasis on arginine in position 8, named Argtide.

A. Janecka, C. Bowers, K. Folkers, 1991, Biochemical and biophysical research communications.

Purification and in vitro and in vivo studies with porcine hypothalamic follicle-stimulating hormone-releasing factor.

W. White, S. Sawano, A. Schally, 1967, Endocrinology.

C. Bowers, K. Folkers, W. Hook, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Design, synthesis and bioassays of antagonists of LHRH which have high antiovulatory activity and release negligible histamine.

C. Bowers, K. Folkers, W. Hook, 1987, Biochemical and biophysical research communications.

Antiovulatory Potency and Conformation of an Antagonist of the Luteinizing Hormone-Releasing Hormone Having Six D-Amino Acids

F. Momany, C. Bowers, T. Kubiak, 1982 .

Inhibitors of the luteinizing hormone-releasing hormone based upon modifications in the 2, 3, and 6 positions.

G. Fisher, C. Bowers, K. Folkers, 1976, Journal of medicinal chemistry.

Effect of [D-Phe2, Pro3, D-Phe6]-luteinizing hormone releasing hormone, an antagonist, on preovulatory gonadotropin secretion in the rhesus monkey.

C. Bowers, K. Folkers, J. Humphries, 1980, Biology of reproduction.

Antagonists of LHRH superior to antide ; effective sequence/activity relationships

C. Bowers, K. Folkers, W. Hook, 1990 .

Antagonists of the luteinizing hormone releasing hormone with pyridyl-alanines which completely inhibit ovulation at nanogram dosage.

J. Stȩpiński, C. Bowers, T. Kubiak, 1983, Biochemical and biophysical research communications.

Luteinizing releasing hormone, synthesis and arg 8 -analogs, and conformation-sequence-activity relationships.

C. Bowers, K. Folkers, J. K. Chang, 1972, Biochemical and biophysical research communications.

Antagonists of LHRH with Histidine in the Priority Position 8

A. Janecka, C. Bowers, K. Folkers, 1993 .

Design, Synthesis and Biological Evaluation of Antagonists of LHRH by Criteria of Potency, Safety and Solubility

C. Bowers, K. Folkers, W. Hook, 1991 .

Inhibitory analogues of the luteinizing hormone-releasing hormone having D-aromatic residues in positions 2 and 6 and variation in position 3.

C. Bowers, K. Folkers, J. Humphries, 1978, Journal of medicinal chemistry.

The structural features of effective antagonists of the luteinizing hormone releasing hormone

A. Janecka, C. Bowers, K. Folkers, 1994, Amino Acids.

Effective antagonists of luteinizing hormone releasing hormone modified at position one

A. Janecka, C. Bowers, K. Folkers, 1993, Amino Acids.

Increased potency of antagonists of the luteinizing hormone releasing hormone which have D-3-Pal in position 6.

C. Bowers, K. Folkers, M. Kubota, 1986, Biochemical and biophysical research communications.

Antagonists of the luteinizing hormone releasing hormone (LHRH) with emphasis on the TRP7 of the salmon and chicken II LHRH's.

C. Bowers, K. Folkers, H. Shieh, 1984, Biochemical and biophysical research communications.

Presence of proline in position 3 for potent inhibition of the activity of the luteinizing hormone releasing hormone and of ovulation.

C. Bowers, K. Folkers, J. Humphries, 1976, Biochemical and biophysical research communications.

Clinical evaluation of a new anabolic agent 7 α, 17 α‐dimethyltestosterone (bolasterone)

C. Bowers, F. Mcmahon, Donald R. Korst, 1963 .

Somatotropic and gonadotropic axes linkages in infancy, childhood, and the puberty-adult transition.

J. Veldhuis, J. Roemmich, E. Richmond, 2006, Endocrine reviews.

Hormonal therapy in cancer of the breast XII. The effect of etiocholanolone therapy on clinical course and hormonal excretion

C. Bowers, A. Segaloff, J. V. Schlosser, 1957, Cancer.

Integrating GHS into the Ghrelin System

J. Veldhuis, C. Bowers, 2010, International journal of peptides.

Growth hormone-releasing peptide-2 infusion synchronizes growth hormone, thyrotrophin and prolactin release in prolonged critical illness.

G. Van den Berghe, G. V. Berghe, F. de Zegher, 1999, European journal of endocrinology.

Variables determining the growth hormone response of His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 in the rat.

F. Momany, O. Sartor, C. Bowers, 1985, Endocrinology.

The effects of growth hormone (GH)-releasing peptides on GH secretion in perifused pituitary cells of adult male rats.

J. B. Martin, W. Millard, T. Badger, 1984, Endocrinology.

Conformational energy studies and in vitro and in vivo activity data on growth hormone-releasing peptides.

F. Momany, C. Bowers, G. Reynolds, 1984, Endocrinology.

Activity of a new synthetic tetrapeptide in hypothalamic luteinizing and follicle stimulating releasing hormone assay systems.

C. Bowers, K. Folkers, J. K. Chang, 1971, Biochemical and biophysical research communications.

Alteration of LH and FSH release in rats treated with clomiphene or its isomers.

A. Schally, D. Holtkamp, A. Arimura, 1970, American journal of obstetrics and gynecology.

Studies on the site of action of oral contraceptive steroids. I. Effect of antifertility steroids on plasma LH levels and on the response to luteinizing hormone-releasing factor in rats.

A. Schally, A. Arimura, C. Bowers, 1968, The Journal of clinical endocrinology and metabolism.

Structure and synthesis of the thyrotropin-releasing hormone.

A. Schally, C. Bowers, K. Folkers, 1971, Journal of medicinal chemistry.

Synthetic thyrotropin-releasing hormone. Activity in men and women, specificity of action, inhibition by triiodothyronine, and activity orally.

A. Kastin, A. Schally, A. Arimura, 1971, Journal of medicinal chemistry.

Porcine thyrotropin releasing hormone is (pyro)glu-his-pro(NH2).

A. Schally, C. Bowers, K. Folkers, 1970, Endocrinology.

Isolation of growth hormone-releasing hormone(GRH) from porcine hypothalami.

S. Sawano, A. Schally, A. Arimura, 1969, Endocrinology.

Effects of mating on gonadotropin release in the female rat.

E. Smith, J. Davidson, C. Bowers, 1973, Endocrinology.

STUDIES ON THE ROLE OF CYCLIC AMP IN THE RELEASE OF ANTERIOR PITUITARY HORMONES *

C. Bowers, 1971, Annals of the New York Academy of Sciences.

Biosynthesis in vitro of the luteinizing releasing hormone by hypothalamic tissue.

C. Bowers, K. Folkers, B. Currie, 1972, Biochemical and biophysical research communications.

Potential thyroliberin affinity labels II: Chloroacetyl substituted phenylalanyl prolineamides.

C. Bowers, B. Currie, R. Goebel, 1982, Journal of pharmaceutical sciences.

Lifetime Regulation of Growth Hormone (GH) Secretion

A. Iranmanesh, J. Veldhuis, F. Roelfsema, 2012 .

Evidence for Separate Corticotrophin- and Luteinizing Hormone-Releasing Factors in Hypothalamic Extracts

A. Schally, C. Bowers, S. Mccann, 1964, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Pheochromocytoma and other apudomas.

C. Bowers, J. Roberts, H. Johnson, 1978, The Journal of urology.

Hormonal therapy in cancer of the breast. XVII. The effect of androsterone on clinical course and hormonal excretion

C. Bowers, A. Segaloff, J. B. Weeth, 1961 .

Hormonal therapy in cancer of the breast XI. The effect of dehydroepiandrosterone on clinical course and hormonal excretion

C. Bowers, D. Gordon, Albert Segaloff, 1957, Cancer.

Identity of Prolactin Inhibiting Factor (PIF) and Luteinizing Hormone-Releasing Factor (LRF).∗

A. Schally, C. Bowers, J. Meites, 1964, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Synthesis and biological activities of pseudopeptide analogues of LH-RH: agonists and antagonists.

W. Vale, C. Bowers, A. Spatola, 1980, Biochemical and biophysical research communications.

Thyrotrophin and prolactin release in prolonged critical illness: dynamics of spontaneous secretion and effects of growth hormone‐secretagogues

G. Van den Berghe, F. de Zegher, R. Bouillon, 1997, Clinical endocrinology.

Demonstration and characterization of the specific binding of growth hormone-releasing peptide to rat anterior pituitary and hypothalamic membranes.

C. Bowers, K. Sethumadhavan, K. Veeraragavan, 1991, Biochemical and biophysical research communications.

Parallel studies of His-DTrp-Ala-Trp-DPhe-Lys-NH2 and human pancreatic growth hormone-releasing factor-44-NH2 in rat primary pituitary cell monolayer culture.

O. Sartor, C. Bowers, D. Chang, 1985, Endocrinology.

Oral estradiol administration modulates continuous intravenous growth hormone (GH)-releasing peptide-2-driven GH secretion in postmenopausal women.

J. Veldhuis, C. Bowers, W. Evans, 2000, The Journal of clinical endocrinology and metabolism.

Structure-activity relationships of a synthetic pentapeptide that specifically releases growth hormone in vitro.

F. Momany, C. Bowers, G. Reynolds, 1980, Endocrinology.

Model-projected mechanistic bases for sex differences in growth hormone regulation in humans.

J. Veldhuis, C. Bowers, L. Farhy, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

The myxedema reflex in infants and children with hypothyroidism.

C. Bowers, A. Segaloff, D. Gordon, 1959, The Journal of pediatrics.

Some studies of the effect of thyroid hormone on the metabolism of the anterior pituitary gland of rats.

K. L. Lee, C. Bowers, O. Miller, 1968, Endocrinology.

EFFECT OF THYROTROPIN ON THE SERUM PROTEIN-BOUND IODINE LEVEL IN VARIOUS THYROID STATES (TSH-PBI TEST)

C. Bowers, W. Locke, D. Gordon, 1961 .

DIFFERENTIATION BETWEEN THYROID AND PARATHYROID CAUSES OF HYPERCALCEMIA

C. Bowers, W. Bortz, E. Eisenberg, 1961 .

Determinants of GH-releasing hormone and GH-releasing peptide synergy in men.

J. Veldhuis, C. Bowers, 2009, American journal of physiology. Endocrinology and metabolism.

Design, synthesis, and biological activity of peptides which release growth hormone in vitro.

F. Momany, C. Bowers, G. Reynolds, 1981, Endocrinology.

Xenobiotic Growth Hormone Secretagogues: Growth Hormone Releasing Peptides

C. Bowers, 1996 .

Maternal—Fetal Endocrine Interrelations: Demonstration of TSH Release from the Fetal Hypophysis in Pregnant Rats Administered Synthetic TRH 1

C. Bowers, N. R. Wall, S. D'angelo, 1971, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Contraception and inhibition of ovulation by minipump infusion of the luteinizing hormone releasing hormone, active analogs and antagonists.

C. Bowers, K. Folkers, 1976, Biochemical and biophysical research communications.

Synthesis of di- and tripeptides and assay in vivo for activity in the thyrotropin releasing hormone and the luteinizing releasing hormone systems.

C. Bowers, K. Folkers, H. Sievertsson, 1972, Journal of medicinal chemistry.

The somatotropic axis in critical illness: effect of continuous growth hormone (GH)-releasing hormone and GH-releasing peptide-2 infusion.

G. Van den Berghe, G. V. Berghe, F. de Zegher, 1997, The Journal of clinical endocrinology and metabolism.

E2 supplementation selectively relieves GH's autonegative feedback on GH-releasing peptide-2-stimulated GH secretion.

S. Anderson, J. Patrie, J. Veldhuis, 2001, The Journal of clinical endocrinology and metabolism.

Synthesis and some biological activities of substance P.

G. Fisher, C. Bowers, K. Folkers, 1974, Journal of medicinal chemistry.

The effects of morphine and other narcotics on thyroid function in mice.

A. Schally, C. Bowers, T. Redding, 1966, Acta endocrinologica.

Intranasal administration of His-D-Trp-Ala-Trp-D-Phe-LysNH2 (growth hormone releasing peptide) increased plasma growth hormone and insulin-like growth factor-I levels in normal men.

Y. Okimura, C. Bowers, K. Chihara, 1991, Endocrinologia japonica.

Estrogen elevates the peak overnight production rate of acylated ghrelin.

J. Veldhuis, C. Bowers, R. Brundage, 2008, The Journal of clinical endocrinology and metabolism.

Ghrelin

M. Andermann, H. Grill, A. Dagher, 2015, Molecular metabolism.

Synthesis and activities of neurotensin , and its acid and amide analogs : Possible natural occurrence of [ Gln 4 ]-neurotensin * ( hypothalamus / tridecapeptide / solid-phase synthesis / natural peptides / hormone )

C. Bowers, E. Susan, Karl FOLKERSt, 2003 .

Evaluation of the anaphylactoid activity of a new LHRH antagonist.

D. Hahn, D. Ritchie, C. Bowers, 1988, Life sciences.

The effect of growth hormone releasing peptide-2 on upper gastrointestinal contractile activity and food intake in conscious dogs

A. Inui, C. Bowers, I. Sasaki, 2009, Journal of Gastroenterology.

GHRP Historical Perspective: Basic and Clinical

C. Bowers, 2000 .

Chapter 2 – GHRP: Unnatural Toward the Natural

C. Bowers, 1999 .

Increased Growth Velocity During Prolonged Ghrp-2 Administration To Growth Hormone Deficient Children (Ghd)

G. Iñiguez, F. Cassorla, A. Ávila, 1997, Pediatric Research.

A New Receptor for Growth Hormone-Release Peptide

C. Bowers, M. Conn, 1996, Science.

GHRP-2, GHRH and SRIF interrelationships during chronic administration of GHRP-2 to humans.

C. Bowers, R. Granda-Ayala, 1996, Journal of pediatric endocrinology & metabolism : JPEM.

Computer-Assisted Modeling of Xenobiotic Growth Hormone Secretagogues

F. Momany, C. Bowers, 1996 .

Effect of substance P/bombesin antagonists on the release of growth hormone by GHRP and GHRH.

D. Coy, C. Bowers, K. Bitar, 1991, Biochemical and biophysical research communications.

Identification and purification of factor B-GHRH from hypothalami which releases growth hormone.

C. Bowers, K. Folkers, B. Currie, 1974, Biochemical and biophysical research communications.

Identification and purification of factor A-GHRH from hypothalami which releases growth hormone.

C. Bowers, T. Greibrokk, K. Folkers, 1974, Biochemical and biophysical research communications.

Analogs of the luteinizing hormone-releasing hormone to study conformational aspects of the aromatic amino acid moieties and inhibition.

G. Fisher, C. Bowers, K. Folkers, 1974, Journal of medicinal chemistry.

The combined administration of GH‐releasing peptide‐2 (GHRP‐2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP‐2 alone

G. Van den Berghe, A. Iranmanesh, R. Baxter, 2002, Clinical endocrinology.

Specificity of Design to Achieve Antagonists of LHRH of Increasing Effectiveness in Therapeutic Activity

C. Bowers, K. Folkers, D. Feng, 1987 .

Prostaglandin Administration to Pregnant Rats: Effects on Pituitary-Target Gland Systems of Mother, Fetus and Neonate 1

C. Bowers, N. R. Wall, S. D'angelo, 1975, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Synthesis of analogs of the thyrotropin-releasing hormone and structure-activity relationship.

C. Bowers, K. Folkers, B. Currie, 1971, Journal of medicinal chemistry.

On the existence and separation of the follicle stimulating hormone releasing hormone from the luteinizing hormone releasing hormone.

C. Bowers, J. Leban, K. Folkers, 1979, Biochemical and biophysical research communications.

Ghrelin as a treatment for amyotrophic lateral sclerosis

C. Bowers, R. Henderson, S. Ngo, 2021, Journal of neuroendocrinology.

On the inhibitory effects of luteinizing hormone-releasing hormone analogs.

C. Bowers, L. Reichert, G. Reynolds, 1980, Endocrinology.

Synergy of L-arginine and growth hormone (GH)-releasing peptide-2 on GH release: influence of gender.

J. Patrie, J. Veldhuis, A. Weltman, 2000, American journal of physiology. Regulatory, integrative and comparative physiology.

Effect of actinomycin D on the inhibitory response of estrogen on LH release.

A. Schally, A. Arimura, C. Bowers, 1969, Endocrinology.

Synthesis and bioassay of LHRH-antagonists with N-Ac-D-O-phenyltyrosine and N-Ac-D-3-(2-dibenzofuranyl)alanine in position 1.

C. Bowers, K. Folkers, A. Ljungqvist, 2009, International journal of peptide and protein research.

Studies on the follicle stimulating hormone releasing hormone by radioimmunoassays and by bioassays.

C. Bowers, K. Folkers, E. Lundanes, 1980, Biochemical and biophysical research communications.

On a peptidomimetic growth hormone-releasing peptide.

C. Bowers, 1994, Journal of Clinical Endocrinology and Metabolism.

Growth hormone-releasing peptide (GHRP) binding to porcine anterior pituitary and hypothalamic membranes.

C. Bowers, K. Sethumadhavan, K. Veeraragavan, 1992, Life sciences.

Age and secretagogue type jointly determine dynamic growth hormone responses to exogenous insulin-like growth factor-negative feedback in healthy men.

A. Iranmanesh, J. Veldhuis, A. Weltman, 2004, The Journal of clinical endocrinology and metabolism.

Continuous 24-hour intravenous infusion of recombinant human growth hormone (GH)-releasing hormone-(1-44)-amide augments pulsatile, entropic, and daily rhythmic GH secretion in postmenopausal women equally in the estrogen-withdrawn and estrogen-supplemented states.

S. Anderson, J. Veldhuis, C. Bowers, 2001, The Journal of clinical endocrinology and metabolism.

Some cardiac problems presented by a thymoma.

T. N. James, C. Bowers, A. Ochsner, 1960, Diseases of the chest.

A new category of ovulation inhibitors: linear LH-RH analogues having more than ten residues.

C. Bowers, K. Folkers, J. Humphries, 1979, Biochemical and biophysical research communications.

Growth hormone (GH)-releasing effects of synthetic peptide GH-releasing peptide-2 and GH-releasing hormone (1-29NH2) in children with GH insufficiency and idiopathic short stature.

C. Bowers, V. Peterkova, N. Volevodz, 1995, Metabolism: clinical and experimental.

On vasodepressor activity in the hypothalamus

W. White, A. Kastin, A. Schally, 1966 .

Synthesis and relationship of L-glutaminyl-L-histidyl-L-prolinamide to the thyrotropin releasing hormone.

A. Schally, C. Bowers, K. Folkers, 1970, Biochemical and biophysical research communications.

An antiovulatory decapeptide of higher potency which has an L-amino acid (Ac-Pro) in position 1.

C. Bowers, K. Folkers, J. Humphries, 1978, Biochemical and biophysical research communications.

Speculations on the Mechanism of Hormone–Receptor Interactions of the Secretin/Glucagon Family of Polypeptide Hormones Derived from Computational Structural Studies

F. Momany, C. Bowers, F. A. MOMANY, 1996, Annals of the New York Academy of Sciences.

Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I), IGF-binding protein-3 (IGFBP-3), and IGFBP-5 concentrations during 30-day continuous subcutaneous infusion of GH-releasing peptide-2 in older men and women.

S. Mohan, J. Veldhuis, C. Bowers, 2004, The Journal of clinical endocrinology and metabolism.

Polypeptides. XLVII. Effect of the pyrazole-imidazole replacement on the biological activity of thyrotropin-releasing hormone.

C. Bowers, K. Hofmann, 1970, Journal of medicinal chemistry.

Thyrotropin and prolactin inhibitory studies by compounds related to the thyrotropin releasing hormone.

K. Andersson, C. Bowers, S. Castensson, 1975, Biochemical and Biophysical Research Communications - BBRC.

Synthetic Peptides that Release TSH and LH from the Pituitary

C. Bowers, K. Folkers, B. Currie, 1972 .

On the conformation of thyrotropin releasing hormone

C. Bowers, Hans Sievertsson, Staffan Castensson, 1974, FEBS letters.

Studies of inhibition of the luteinizing hormone-releasing hormone by an irreversible inhibitor at the receptor site.

C. Bowers, K. Folkers, J. Humphries, 1974, Biochemical and biophysical research communications.

On the role of the histidine moiety in the structure of the thyrotropin-releasing hormone.

C. Bowers, K. Folkers, H. Sievertsson, 1972, Journal of medicinal chemistry.

Activity-structure relationships of the thyrotropin releasing hormone.

C. Bowers, K. Folkers, F. Enzmann, 1970, Biochemical and biophysical research communications.

Data on structure of bovine LRH by inactivation.

C. Bowers, K. Folkers, B. Currie, 1971, Biochemical and biophysical research communications.

New advances on the regulation of growth hormone (GH) secretion.

F. Momany, C. Bowers, G. Reynolds, 1984, International journal of neurology.

Pre- versus postmenopausal age, estradiol, and peptide-secretagogue type determine pulsatile growth hormone secretion in healthy women: studies using submaximal agonist drive and an estrogen clamp.

D. Schroeder, J. Veldhuis, J. Miles, 2010, The Journal of clinical endocrinology and metabolism.

The simultaneous determination of both the quantity and the fatty acid composition of the triglycerides in three to ten microliters of plasma

A. Schally, C. Bowers, G. Reynolds, 1966, Journal of the American Oil Chemists Society.

Biological activities of thionated thyrotropin-releasing hormone analogs.

L. Lankiewicz, C. Bowers, A. Sirén, 1992, Biochemical and biophysical research communications.

EFFECTS OF AGE, SEX, CASTRATION AND THE ADMINISTRATION OF TESTOSTERONE AND ESTRADIOL ON LEVELS OF SERUM CHOLESTERYL ESTER FATTY ACIDS IN RATS.

A. Schally, C. Bowers, 1965, Endocrinology.

Growth hormone (GH) responses to GH-releasing peptide and to GH-releasing hormone in GH-deficient children.

V. Mericq, F. Cassorla, A. Ávila, 1995, Journal of Clinical Endocrinology and Metabolism.

Changes in Appetite and Body Weight in Response to Long-term Oral Administration of the Ghrelin Agonist GHRP-2 in Growth Hormone Deficient Children

V. Mericq, A. Ávila, C. Bowers, 2003, Journal of Pediatric Endocrinology & Metabolism (JPEM).

Validation of growth-hormone-releasing peptide 2 for the diagnosis of adult growth hormone deficiency

J. Veldhuis, C. Bowers, G. Merriam, 2007, Nature Clinical Practice Endocrinology &Metabolism.

Factors affecting the thyroid gland uptake of I 131 of the Rana catesbeiana tadpole.

B. Brown, C. Bowers, A. Segaloff, 1959, Endocrinology.

Photo-oxidation of thyrotropin releasing hormone

J. Kennedy, A. Schally, C. Bowers, 1971 .

In vivo effects of the GH-releasing heptapeptide GHRP-1 in lambs.

C. Bowers, R. Guilhermet, A. Fraysse, 1998, Reproduction, nutrition, development.

Estrogen supplementation selectively enhances hypothalamo-pituitary sensitivity to ghrelin in postmenopausal women.

J. Veldhuis, J. Miles, C. Bowers, 2008, The Journal of clinical endocrinology and metabolism.

Ghrelin: A History of Its Discovery

J. Veldhuis, C. Bowers, G. Reynolds, 2012 .

Complex regulation of GH autofeedback under dual-peptide drive: studies under a pharmacological GH and sex steroid clamp.

J. Veldhuis, J. Miles, C. Bowers, 2011, American journal of physiology. Endocrinology and metabolism.

Effects of acute and chronic administration of TRH on TSH and prolactin secretion in normal and hypothyroid rats.

C. Bowers, N. R. Wall, S. D'angelo, 1975, Neuroendocrinology.

CHEMISTRY AND PHYSIOLOGY OF FOLLICLE-STIMULATING HORMONE-RELEASING FACTOR AND LUTEINIZING HORMONE-RELEASING FACTOR*

A. Schally, A. Arimura, C. Bowers, 1968 .

Relative effects of estrogen, age, and visceral fat on pulsatile growth hormone secretion in healthy women.

J. Veldhuis, C. Bowers, G. Reynolds, 2009, American journal of physiology. Endocrinology and metabolism.

Octanoyl ghrelin is hypothalamic rooted.

C. Bowers, 2005, Endocrinology.

Activity of growth hormone-releasing peptide-2 in cultured human pituitary adenoma cells and its interaction with growth hormone-releasing hormone and somatostatin

T. A. Osipova, C. Bowers, A. Martynov, 1998, Bulletin of Experimental Biology and Medicine.

Studies on analogs of the luteinizing releasing hormone towards elucidation of the release mechanism.

C. Bowers, K. Folkers, H. Sievertsson, 1972, Biochemical and biophysical research communications.

Discovery of a new synthetic tetrapeptide having luteinizing releasing hormone (LRH) activity.

C. Bowers, K. Folkers, B. Currie, 1971, Biochemical and biophysical research communications.

Activity and specificity of synthetic thyrotropin-releasing hormone in man.

A. Kastin, A. Schally, C. Bowers, 1970, Biochemical and biophysical research communications.

Complex regulation of GH autofeedback under dual-peptide drive: studies under a pharmacological GH and sex steroid clamp.

J. Veldhuis, J. Miles, C. Bowers, 2011, American Journal of Physiology. Endocrinology and Metabolism.

Novel relationships of age, visceral adiposity, insulin-like growth factor (IGF)-I and IGF binding protein concentrations to growth hormone (GH) releasing-hormone and GH releasing-peptide efficacies in men during experimental hypogonadal clamp.

D. M. Keenan, J. Veldhuis, J. Miles, 2009, The Journal of clinical endocrinology and metabolism.