J. Latham

发表

Effects of alkoxy groups on arene rings of lignin β-O-4 model compounds on the efficiencies of single electron transfer-promoted photochemical and enzymatic C-C Bond Cleavage Reactions.

Dae Won Cho, D. Dunaway-Mariano, K. Nahm, 2013, The Journal of organic chemistry.

Selection of single-stranded DNA molecules that bind and inhibit human thrombin

E. Vermaas, J. Latham, L. C. Bock, 1992, Nature.

A unified phylogeny-based nomenclature for histone variants

S. Henikoff, D. Landsman, G. Cross, 2012, Epigenetics & Chromatin.

Occurrence, function, and biosynthesis of mycofactocin

J. Latham, Richard S Ayikpoe, V. Govindarajan, 2019, Applied Microbiology and Biotechnology.

At the confluence of ribosomally synthesized peptide modification and radical S-adenosylmethionine (SAM) enzymology

J. Klinman, J. Latham, Ian Barr, 2017, The Journal of Biological Chemistry.

Mechanistic elucidation of the mycofactocin-biosynthetic radical S-adenosylmethionine protein, MftC

J. Latham, Richard S Ayikpoe, Bulat Khaliullin, 2017, The Journal of Biological Chemistry.

The pyrroloquinoline quinone ( PQQ ) biosynthetic pathway : Demonstration of de novo carbon-carbon cross-linking within the peptide substrate ( PqqA ) in the presence of the Radical SAM enzyme ( PqqE ) and its peptide chaperone ( PqqD )

J. Klinman, A. T. Iavarone, J. Latham, 2016 .

Demonstration That the Radical S-Adenosylmethionine (SAM) Enzyme PqqE Catalyzes de Novo Carbon-Carbon Cross-linking within a Peptide Substrate PqqA in the Presence of the Peptide Chaperone PqqD*♦

J. Klinman, A. T. Iavarone, J. Latham, 2016, The Journal of Biological Chemistry.

PqqD Is a Novel Peptide Chaperone That Forms a Ternary Complex with the Radical S-Adenosylmethionine Protein PqqE in the Pyrroloquinoline Quinone Biosynthetic Pathway*

J. Klinman, A. T. Iavarone, J. Latham, 2015, The Journal of Biological Chemistry.

Human brown fat inducible thioesterase variant 2 cellular localization and catalytic function.

Hong Zhao, D. Dunaway-Mariano, J. Latham, 2012, Biochemistry.

Sclerostin promotes the apoptosis of human osteoblastic cells: a novel regulation of bone formation.

J. Latham, E. Turcott, James C. Geoghegan, 2004, Bone.

Induction of Migraine-Like Photophobic Behavior in Mice by Both Peripheral and Central CGRP Mechanisms

J. Latham, A. Russo, Eric A. Kaiser, 2017, The Journal of Neuroscience.

Retention of configuration in oxidation of a chiral boronic acid by the flavoenzyme cyclohexanone oxygenase

C. Walsh, J. Latham, 1986 .

MftD Catalyzes the Formation of a Biologically Active Redox Center in the Biosynthesis of the Ribosomally Synthesized and Post-translationally Modified Redox Cofactor, Mycofactocin.

J. Latham, Richard S Ayikpoe, Richard S. Ayikpoe, 2019, Journal of the American Chemical Society.

Catalytic Mechanism of the Hotdog‐Fold Thioesterase PA1618 Revealed by X‐ray Structure Determination of a Substrate‐Bound Oxygen Ester Analogue Complex

Karen N. Allen, D. Dunaway-Mariano, J. Latham, 2017, Chembiochem : a European journal of chemical biology.

Discovery of Hydroxylase Activity for PqqB Provides a Missing Link in the Pyrroloquinoline Quinone Biosynthetic Pathway.

J. Klinman, C. Wilmot, J. Latham, 2019, Journal of the American Chemical Society.

A simple, reproducible and cheap batch method for the analysis of serum glycoproteins using sepharose-coupled lectins and silver staining.

J. Latham, S. Thompson, G. Turner, 1987, Clinica chimica acta; international journal of clinical chemistry.

Investigation of the catalytic mechanism of the hotdog-fold enzyme superfamily Pseudomonas sp. strain CBS3 4-hydroxybenzoyl-CoA thioesterase.

Zhihao Zhuang, F. Song, D. Dunaway-Mariano, 2012, Biochemistry.

Structural insights for vanadium catecholates and iron‑sulfur clusters obtained from multiple data analysis methods applied to electron spin relaxation data.

S. Eaton, G. Eaton, J. Latham, 2019, Journal of inorganic biochemistry.

The biological activity of retinoids in melanoma cells

J. Latham, A. Daly, C. Todd, 1990, FEBS letters.

Mycofactocin Biosynthesis Proceeds through 3-Amino-5-[( p-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidinone (AHDP); Direct Observation of MftE Specificity toward MftA.

J. Latham, B. Majestic, Richard S Ayikpoe, 2018, Biochemistry.

NMR structure and binding studies of PqqD, a chaperone required in the biosynthesis of the bacterial dehydrogenase cofactor pyrroloquinoline quinone

J. Klinman, J. Latham, Youlin Xia, 2017 .

Mechanism-based inactivation of the flavoenzyme cyclohexane oxygenase during oxygenation of cyclic thiol ester substrates

C. Walsh, J. Latham, 1987 .

A two-component protease in Methylorubrum extorquens with high activity toward the peptide precursor of the redox cofactor pyrroloquinoline quinone

J. Klinman, P. Martel, J. Latham, 2019, The Journal of Biological Chemistry.

Self-splicing and enzymatic cleavage of RNA by a group I intervening sequence.

T. Cech, A. Zaug, J. Latham, 1990, Methods in enzymology.

Regioselectivity of enzymatic and photochemical single electron transfer promoted carbon-carbon bond fragmentation reactions of tetrameric lignin model compounds.

Dae Won Cho, D. Dunaway-Mariano, P. Langan, 2011, The Journal of organic chemistry.

Mycofactocin biosynthesis: modification of the peptide MftA by the radical S‐adenosylmethionine protein MftC

S. Eaton, G. Eaton, J. Latham, 2016, FEBS letters.

Unique regulation of SOST, the sclerosteosis gene, by BMPs and steroid hormones in human osteoblasts.

J. Latham, James C. Geoghegan, D. Winkler, 2004, Bone.

Structure to function : case studies of hotdog-fold superfamily thioesterases from Escherichia coli.

J. Latham, 2012 .

How a Subfamily of Radical S-Adenosylmethionine Enzymes Became a Mainstay of Ribosomally Synthesized and Post-translationally Modified Peptide Discovery

J. Latham, Y. Lien, A. Kostenko, 2021, ACS bio & med chem Au.

Sclerostin Inhibition of Wnt-3a-induced C3H10T1/2 Cell Differentiation Is Indirect and Mediated by Bone Morphogenetic Proteins*

J. Latham, E. Turcott, James C. Geoghegan, 2005, Journal of Biological Chemistry.

Noggin and Sclerostin Bone Morphogenetic Protein Antagonists Form a Mutually Inhibitory Complex*

J. Latham, James C. Geoghegan, D. Winkler, 2004, Journal of Biological Chemistry.

Mechanism-Based Inactivation of the Flavoenzyme Cyclohexanone Oxygenase During Oxygenation of Cyclic Thiol Ester Substrates.

C. Walsh, J. Latham, 1987 .

Benzobicyclooctanes as novel inhibitors of TNF-α signaling

J. Howbert, F. Ramsdell, J. Latham, 2002 .

Mechanism-based inactivation of the flavoprotein cyclohexanone monooxygenase by S oxygenation

C. Walsh, J. Latham, 1986 .

Human Brown Fat Inducible Thioesterase Variant 2 (BFIT2) Cellular Localization and Catalytic Function#

Debra, J. Latham, M. Bisoffi, 2014 .

New developments in RiPP discovery, enzymology and engineering.

Lutz Schmitt, Jin Zhong, Roderich D Süssmuth, 2020, Natural product reports.

Defining the inside and outside of a catalytic RNA molecule.

T. Cech, J. Latham, T R Cech, 1989, Science.

Photochemical and enzymatic SET promoted C–C bond cleavage reactions of lignin β-1 model compounds containing varying number of methoxy substituents on their arene rings

Dae Won Cho, D. Dunaway-Mariano, Cheolhee Kim, 2015 .

Spectroscopic and Electrochemical Characterization of the Mycofactocin Biosynthetic Protein, MftC, Provides Insight into Its Redox Flipping Mechanism.

S. Elliott, S. Eaton, G. Eaton, 2019, Biochemistry.

The application of a modified nucleotide in aptamer selection: novel thrombin aptamers containing 5-(1-pentynyl)-2'-deoxyuridine.

J. Latham, J. Toole, J A Latham, 1994, Nucleic acids research.

Immunohistochemical markers of human sebaceous gland differentiation.

J. Latham, A. Thody, C. Redfern, 1989, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

X-ray and EPR Characterization of the Auxiliary Fe-S Clusters in the Radical SAM Enzyme PqqE.

J. Klinman, S. Almo, J. Bonanno, 2018, Biochemistry.

Cross-regulation of histone modifications

John A Latham, Sharon Y. R. Dent, J. Latham, 2007, Nature Structural &Molecular Biology.

A Novel Mutation in CD83 Results in the Development of a Unique Population of CD4+ T Cells

S. Proll, B. Paeper, K. Staehling-Hampton, 2004, The Journal of Immunology.

Chromatin Signaling to Kinetochores: Transregulation of Dam1 Methylation by Histone H2B Ubiquitination

Sharon Y. R. Dent, J. Latham, Shanzhi Wang, 2011, Cell.

Identification of a poly-cyclopropylglycine–containing peptide via bioinformatic mapping of radical S-adenosylmethionine enzymes

S. Eaton, J. Latham, Y. Lien, 2022, The Journal of biological chemistry.

Regulation of Set1-mediated methylation of Dam1

J. Latham, 2011 .

Divergence of Substrate Specificity and Function in the Escherichia coli Hotdog-fold Thioesterase Paralogs YdiI and YbdB

Karen N. Allen, D. Dunaway-Mariano, J. Latham, 2014, Biochemistry.

Polymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites.

A. Uitterlinden, J. V. van Meurs, F. Rivadeneira, 2004, American journal of human genetics.

1H, 13C, and 15N resonance assignments and secondary structure information for Methylobacterium extorquens PqqD and the complex of PqqD with PqqA

J. Klinman, C. Wilmot, J. Latham, 2016, Biomolecular NMR Assignments.

1H, 13C, and 15N resonance assignments and secondary structure information for Methylobacterium extorquens PqqD and the complex of PqqD with PqqA

J. Klinman, C. Wilmot, J. Latham, 2016, Biomolecular NMR assignments.

Nuclear Magnetic Resonance Structure and Binding Studies of PqqD, a Chaperone Required in the Biosynthesis of the Bacterial Dehydrogenase Cofactor Pyrroloquinoline Quinone.

J. Klinman, C. Wilmot, J. Latham, 2017, Biochemistry.

Mechanistic Studies on Mercuric Ion Reductase and Cyclohexanone Oxygenase: Pharmacologic and Toxicologic Aspects

B. Branchaud, J. Latham, B. Fox, 1983 .

ALD1613, a Novel Long-Acting Monoclonal Antibody to Control ACTH-Driven Pharmacology

J. Mulligan, J. Latham, M. Scalley‐Kim, 2016, Endocrinology.

T Cells +of a Unique Population of CD4 A Novel Mutation in CD83 Results in the

B. Paeper, J. Latham, D. M. Andrews, 2017 .

The Set1 Methyltransferase Opposes Ipl1 Aurora Kinase Functions in Chromosome Segregation

Ryuji Kobayashi, David H. Hawke, Sharon Y. R. Dent, 2005, Cell.

Nicotinamide N-oxides as CXCR2 antagonists.

J. Latham, N. Ihle, K. Kucera, 2001, Bioorganic & medicinal chemistry letters.

Nicotinanilides as inhibitors of neutrophil chemotaxis.

J. Latham, N. Ihle, K. Kucera, 2002, Bioorganic & medicinal chemistry letters.

The catalytic mechanism of the hotdog-fold enzyme superfamily 4-hydroxybenzoyl-CoA thioesterase from Arthrobacter sp. strain SU.

Zhihao Zhuang, F. Song, D. Dunaway-Mariano, 2012, Biochemistry.

Pharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related Peptide

J. Latham, M. Scalley‐Kim, B. Baker, 2020, The Journal of Pharmacology and Experimental Therapeutics.

Biosynthesis of the redox cofactor mycofactocin is controlled by the transcriptional regulator MftR and induced by long-chain acyl-CoA species

J. Latham, Aigera Mendauletova, 2021, The Journal of biological chemistry.

Crystal structures reveal metal-binding plasticity at the metallo-β-lactamase active site of PqqB from Pseudomonas putida

J. Klinman, C. Wilmot, J. Latham, 2017, JBIC Journal of Biological Inorganic Chemistry.

Pharmacologic Characterization of ALD1910, a Potent Humanized Monoclonal Antibody against the Pituitary Adenylate Cyclase-Activating Peptide

J. Mulligan, R. Cady, S. Pederson, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Gastroduodenal Epithelial Cells: The Role of the Apical Membrane in Mucosal Protection

B. Hirst, J. Latham, H. Ballard, 1987 .

Crystal structures reveal metal-binding plasticity at the metallo-β-lactamase active site of PqqB from Pseudomonas putida

J. Klinman, C. Wilmot, J. Latham, 2017, JBIC Journal of Biological Inorganic Chemistry.

A unified phylogeny-based nomenclature for histone variants

S. Henikoff, D. Landsman, G. Cross, 2012, Epigenetics & Chromatin.

Structure and Catalysis in the Escherichia coli Hotdog-fold Thioesterase Paralogs YdiI and YbdB

Karen N. Allen, Hong Zhao, R. Wu, 2014, Biochemistry.

The H2BK123Rgument

Sharon Y. R. Dent, J. Latham, 2009, The Journal of cell biology.

Induction of Migraine-Like Photophobic Behavior in Mice by Both Peripheral and Central CGRP Mechanisms

J. Latham, A. Russo, Eric A. Kaiser, 2017, The Journal of Neuroscience.