C. Secombes

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Isolation and characterization of CXC receptor genes in a range of elasmobranchs.

Gareth T. Jones, A. Goostrey, C. Secombes, 2005, Developmental and comparative immunology.

2 - The Nonspecific Immune System: Cellular Defenses

C. Secombes, 1996 .

Detection of specific and 'constitutive' antibody secreting cells in the gills, head kidney and peripheral blood leucocytes of dab (Limanda limanda).

S. H. Lin, C. Secombes, A. Ellis, 1997, Veterinary immunology and immunopathology.

A morphological study of cells isolated from the perfused gill of dab and Atlantic salmon

C. Secombes, A. Ellis, G. A. Davidson, 1998 .

The immune system of sea bass, Dicentrarchus labrax, reared in aquaculture.

F. Buonocore, G. Scapigliati, C. Secombes, 2002, Developmental and comparative immunology.

Intron-Containing Type I and Type III IFN Coexist in Amphibians: Refuting the Concept That a Retroposition Event Gave Rise to Type I IFNs

C. Secombes, P. Nie, Z. Qi, 2010, The Journal of Immunology.

Molecular characterization and expression analysis of the IFN-gamma related gene (IFN-gammarel) in grass carp Ctenopharyngodon idella.

C. Secombes, P. Nie, J. Zou, 2010, Veterinary immunology and immunopathology.

Expression and Functional Characterization of the RIG-I-Like Receptors MDA5 and LGP2 in Rainbow Trout (Oncorhynchus mykiss)

C. Secombes, P. Nie, M. Chang, 2011, Journal of Virology.

Complete sequencing and expression of three complement components, C1r, C4 and C1 inhibitor, of the classical activation pathway of the complement system in rainbow trout Oncorhynchus mykiss

C. Secombes, Tiehui Wang, 2003, Immunogenetics.

Recombinant interleukin-1β dilates steelhead trout coronary microvessels: effect of temperature and role of the endothelium, nitric oxide and prostaglandins

T. Hein, C. Secombes, I. Costa, 2015, The Journal of Experimental Biology.

Rapid isolation of IgNAR variable single-domain antibody fragments from a shark synthetic library.

C. Secombes, C. Shao, A. Porter, 2007, Molecular immunology.

In vitro evaluation of novel (nanoparticle) oral delivery systems allow selection of gut immunomodulatory formulations.

Mukhtar Ahmed, Suzanne Saffie-Siebert, C. Secombes, 2021, Fish & shellfish immunology.

A recombinant CHSE-214 cell line expressing an Mx1 promoter-reporter system responds to both interferon type I and type II from salmonids and represents a versatile tool to study the IFN-system in teleost fish.

M. Hegseth, C. Secombes, B. Robertsen, 2007, Fish & shellfish immunology.

Immunostimulation in the rainbow trout (Oncorhynchus mykiss) following intraperitoneal administration of Ergosan.

C. Secombes, J. Zou, S. Peddie, 2002, Veterinary immunology and immunopathology.

Interaction between eicosanoids and the complement system in salmonid fish.

G. Taylor, C. Secombes, J. Sunyer, 2012, Developmental and comparative immunology.

Multiple tissue transcriptomic responses to Piscirickettsia salmonis in Atlantic salmon (Salmo salar).

J. Taggart, J. Bron, C. Secombes, 2011, Physiological genomics.

Cytokines: an evolutionary perspective.

C. Secombes, C. Cunningham, 2004, Developmental and comparative immunology.

Polychlorinated biphenyl 126 affects expression of genes involved in stress‐immune interaction in primary cultures of rainbow trout anterior kidney cells

C. Secombes, G. Krupp, E. Quabius, 2005, Environmental toxicology and chemistry.

Modelling β − Trefoil Proteins Using an Object-Oriented Database

D. Ritchie, C. Secombes, A. Koussounadis, 2004 .

DNA vaccination against a fish rhabdovirus promotes an early chemokine-related recruitment of B cells to the muscle.

C. Secombes, E. Lorenzen, U. Fischer, 2014, Vaccine.

Genomic Tools for Examining Immune Gene Function in Salmonid Fish

Ø. Evensen, S. Mackenzie, C. Secombes, 2008 .

Effects of repeated anaesthesia on gill and general health of Atlantic salmon, Salmo salar.

C. Collins, C. Secombes, G. Cameron, 2018, Journal of fish biology.

Lipoxin‐induced migration of fish leukocytes

T. Pettitt, C. Secombes, A. Rowley, 1992, Journal of leukocyte biology.

Gene expression analysis of isolated salmonid GALT leucocytes in response to PAMPs and recombinant cytokines

C. Secombes, J. Zou, Ahmed Attaya, 2018, Fish & shellfish immunology.

Effect of repeated exposure to AQUI‐S® on the viability and growth of Neoparamoeba perurans

C. Collins, C. Secombes, B. Collet, 2017, Journal of fish diseases.

Dual Mutation Events in the Haemagglutinin-Esterase and Fusion Protein from an Infectious Salmon Anaemia Virus HPR0 Genotype Promote Viral Fusion and Activation by an Ubiquitous Host Protease

K. Falk, C. Secombes, B. Collet, 2015, PloS one.

Rainbow trout [Oncorhynchus mykiss (Walbaum, 1792)] leucocyte interactions with metacestode stages of Diphyllobothrium dendriticum (Nitzsch, 1824), (Cestoda, Pseudophyllidea)

C. Secombes, G. Sharp, A. Pike, 1991 .

Protection of rainbow trout, Oncorhynchus mykiss (Richardson), against Diplostomum spathaceum (Digenea): the role of specific antibody and activated macrophages

S. Whyte, C. Secombes, L. Chappell, 1990 .

Evolution of Interferons and Interferon Receptors

C. Secombes, J. Zou, 2017, Front. Immunol..

Lineage/species-specific expansion of the Mx gene family in teleosts: Differential expression and modulation of nine Mx genes in rainbow trout Oncorhynchus mykiss.

C. Secombes, Tiehui Wang, G. Tian, 2019, Fish & shellfish immunology.

The CXC chemokine receptors of fish: Insights into CXCR evolution in the vertebrates.

C. Secombes, Z. Qi, J. Zou, 2015, General and comparative endocrinology.

Rainbow trout cytokine and cytokine receptor genes

G. Kemp, C. Secombes, C. Cunningham, 1998, Immunological reviews.

Fish Immune Responses to Myxozoa

H. Schmidt-Posthaus, T. Wahli, C. Secombes, 2015 .

Muscle-Specific RING Finger (MuRF) cDNAs in Atlantic Salmon (Salmo salar) and Their Role as Regulators of Muscle Protein Degradation

C. Secombes, Samuel A M Martin, L. Tacchi, 2011, Marine Biotechnology.

Ubiquitin E3 ligase atrogin-1 (Fbox-32) in Atlantic salmon (Salmo salar): sequence analysis, genomic structure and modulation of expression.

C. Secombes, Samuel A M Martin, B. Collet, 2010, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Individual measurement of gene expression in blood cells from Rainbow trout Oncorhynchus mykiss (Walbaum)

C. Collins, C. Secombes, B. Collet, 2016 .

A CD4 homologue in sea bass (Dicentrarchus labrax): molecular characterization and structural analysis.

S. Costantini, F. Buonocore, G. Scapigliati, 2008, Molecular immunology.

The First Cytokine Sequence Within Cartilaginous Fish: IL-1β in the Small Spotted Catshark (Scyliorhinus canicula)1

C. Secombes, C. Cunningham, J. Zou, 2002, The Journal of Immunology.

Expansion of fish CCL20_like chemokines by genome and local gene duplication: Characterisation and expression analysis of 10 CCL20_like chemokines in rainbow trout (Oncorhynchus mykiss).

C. Secombes, Tiehui Wang, G. Tian, 2020, Developmental and comparative immunology.

The protective mechanisms induced by a fish rhabdovirus DNA vaccine depend on temperature.

C. Secombes, E. Lorenzen, B. Collet, 2009, Vaccine.

Isolation of rainbow trout neutrophils with an anti-granulocyte monoclonal antibody.

H. Wergeland, C. Endresen, C. Secombes, 1998, Veterinary immunology and immunopathology.

Cross Talk Between Growth and Immunity: Coupling of the IGF Axis to Conserved Cytokine Pathways in Rainbow Trout.

Samuel A. M. Martin, P. Boudinot, C. Secombes, 2016, Endocrinology.

Characterization of three pro-inflammatory cytokines, TNFα1, TNFα2 and IL-1β, in cage-reared Atlantic bluefin tuna Thunnus thynnus.

C. Secombes, Ivana Lepen Pleić, I. Mladineo, 2014, Fish & shellfish immunology.

Molecular characterisation and structural analysis of an interferon homologue in sea bass (Dicentrarchus labrax L.).

S. Costantini, F. Buonocore, G. Scapigliati, 2009, Molecular immunology.

The CD8alpha from sea bass (Dicentrarchus labrax L.): Cloning, expression and 3D modelling.

S. Costantini, F. Buonocore, G. Scapigliati, 2006, Fish & shellfish immunology.

Interleukin (IL)-2 Is a Key Regulator of T Helper 1 and T Helper 2 Cytokine Expression in Fish: Functional Characterization of Two Divergent IL2 Paralogs in Salmonids

C. Secombes, M. Imarai, Tiehui Wang, 2018, Front. Immunol..

First in-depth analysis of the novel Th2-type cytokines in salmonid fish reveals distinct patterns of expression and modulation but overlapping bioactivities

Amy Holt, C. Secombes, Yousheng Jiang, 2016, Oncotarget.

Molecular characterisation of four class 2 cytokine receptor family members in rainbow trout, Oncorhynchus mykiss.

C. Secombes, J. Zou, B. Collet, 2015, Developmental and comparative immunology.

B cell receptor accessory molecule CD 79 a : Characterisation and expression analysis in a cartilaginous fi sh , the spiny dog fi sh ( Squalus acanthias )

Ronggai Li, C. Secombes, J. Zou, 2013 .

Cloning of the IL-1β3 gene and IL-1β4 pseudogene in salmonids uncovers a second type of IL-1β gene in teleost fish.

C. Secombes, Tiehui Wang, Ruthger W van Zwieten, 2012, Developmental and comparative immunology.

Characterisation and expression analysis of an interleukin 6 homologue in the Japanese pufferfish, Fugu rubripes.

C. Secombes, R. Savan, J. Zou, 2005, Developmental and comparative immunology.

Identification of a Novel Cathelicidin Gene in the Rainbow Trout, Oncorhynchus mykiss

Yongan Zhang, O. Pleguezuelos, C. Secombes, 2005, Infection and Immunity.

Expression of an inducible nitric oxide synthase gene in rainbow trout Oncorhynchus mykiss.

C. Secombes, L. Hardie, P. Grabowski, 1999, Developmental and comparative immunology.

Molecular cloning of interleukin 1beta from rainbow trout Oncorhynchus mykiss reveals no evidence of an ice cut site.

C. Secombes, C. Cunningham, J. Zou, 1999, Cytokine.

A partial sequence for nitric oxide synthase from a goldfish (Carassius auratus) macrophage cell line

M. Belosevic, C. Secombes, P. Grabowski, 1996, Immunology and cell biology.

Characterisation of arginase paralogues in salmonids and their modulation by immune stimulation/ infection

C. Collins, C. Secombes, Tiehui Wang, 2017, Fish & shellfish immunology.

Which Th pathway is involved during late stage amoebic gill disease?

C. Collins, C. Secombes, Tiehui Wang, 2015, Fish & shellfish immunology.

Functional characterisation of a TLR accessory protein, UNC93B1, in Atlantic salmon (Salmo salar).

C. Secombes, J. Zou, J. Holland, 2015, Developmental and comparative immunology.

parasiticaby the Oomycete Saprolegnia Fish Immune Response and Suppression of in 2 Carbohydrates and Prostaglandin E Role of Pathogen-Derived Cell Wall

P. West, V. Bulone, C. Secombes, 2014 .

Role of Pathogen-Derived Cell Wall Carbohydrates and Prostaglandin E2 in Immune Response and Suppression of Fish Immunity by the Oomycete Saprolegnia parasitica

V. Bulone, P. van West, C. Secombes, 2014, Infection and Immunity.

Vertebrate Cytokines and Their Evolution

C. Secombes, Tiehui Wang, S. Bird, 2016 .

Discovery of zebrafish (Danio rerio) interleukin-23 alpha (IL-23α) chain, a subunit important for the formation of IL-23, a cytokine involved in the development of Th17 cells and inflammation.

Amy Holt, A. M. van der Sar, C. Secombes, 2011, Molecular immunology.

Identification of a Novel IL-1 Cytokine Family Member in Teleost Fish1

C. Secombes, J. Zou, Tiehui Wang, 2009, The Journal of Immunology.

Type I Interferon Regulates the Survival and Functionality of B Cells in Rainbow Trout

C. Secombes, C. Tafalla, Tiehui Wang, 2020, Frontiers in Immunology.

Disparate developmental patterns of immune responses to bacterial and viral infections in fish

Samuel A. M. Martin, L. Jouneau, P. Boudinot, 2015, Scientific Reports.

Molecular and Functional Characterization of IL-15 in Rainbow Trout Oncorhynchus mykiss: A Potent Inducer of IFN- Expression in Spleen Leukocytes

C. Secombes, Tiehui Wang, J. Holland, 2007 .

Immunocompetence as a measure of the biological effects of sewage sludge pollution in fish.

R. Stagg, D. Houlihan, Mark John Costello, 1991, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

Non-specific immune responses in families of Atlantic salmon, Salmo salar, exhibiting differential resistance to furunculosis

L. C. Freeman, C. Secombes, M. J. Marsden, 1996 .

Human tumor necrosis factor α influences rainbow trout Oncorhynchus mykiss leucocyte responses

C. Secombes, L. Hardie, L. Chappell, 1994 .

Functional characterisation of the recombinant tumor necrosis factors in rainbow trout, Oncorhynchus mykiss.

G. Scapigliati, C. Secombes, N. Bols, 2003, Developmental and comparative immunology.

Identifying potential virulence determinants in viral haemorrhagic septicaemia virus (VHSV) for rainbow trout.

C. Secombes, M. Snow, B. Collet, 2009, Diseases of aquatic organisms.

Superoxide anion production by rainbow trout macrophages detected by the reduction of ferricytochrome C.

C. Secombes, S. Chung, A. H. Jeffries, 1988, Developmental and comparative immunology.

Effect of short-term exposure to oil-contaminated sediments on the immune response of dab, Limanda limanda (L.)

D. Houlihan, C. Secombes, T. C. Fletcher, 1993 .

Effects of sewage sludge on immune responses in the dab, Limanda limanda (L.)

R. Stagg, D. Houlihan, Mark John Costello, 1992 .

Rainbow trout (Oncorhynchus mykiss) adipose tissue undergoes major changes in immune gene expression following bacterial infection or stimulation with pro‐inflammatory molecules

C. Secombes, Tiehui Wang, K. Veenstra, 2018, Developmental and comparative immunology.

Immune parameters of plaice, Pleuronectes platessa, L. along a sewage sludge gradient in the Firth of Clyde, Scotland

R. Stagg, D. Houlihan, C. Secombes, 1995, Ecotoxicology.

The production of a macrophage-activating factor from rainbow trout Salmo gairdneri leucocytes.

C. Secombes, S. Graham, 1988, Immunology.

A novel assay to detect macrophage bactericidal activity in fish: factors influencing the killing of Aeromonas salmonicida

C. Secombes, S. Graham, A. H. Jeffries, 1988 .

Lipoxins are major lipoxygenase products of rainbow trout macrophages

T. Pettitt, C. Secombes, A. Rowley, 1989, FEBS letters.

Oxygen Uptake of Rainbow Trout Oncorhynchus Mykiss Phagocytes Following Stimulation of the Respiratory Burst

D. Houlihan, C. Secombes, L. Nagelkerke, 1990 .

Do fish lymphocytes secrete interferon‐γ?

C. Secombes, S. Graham, 1990 .

Cytotoxic reactions of rainbow trout, Salmo gairdneri Richardson, macrophages for larvae of the eye fluke Diplostomum spathaceum (Digenea)

S. Whyte, C. Secombes, L. Chappell, 1989 .

Immunological activation of rainbow trout macrophages induced in vitro by sperm autoantibodies and factors derived from testis sensitised leucocytes.

C. Secombes, 1986, Veterinary immunology and immunopathology.

Differential responses of the gut transcriptome to plant protein diets in farmed Atlantic salmon

J. Speakman, D. Tocher, C. Secombes, 2016, BMC Genomics.

Fish immunity: the potential impact on vaccine development and performance

C. Secombes, 2011 .

Identification of two FoxP3 genes in rainbow trout (Oncorhynchus mykiss) with differential induction patterns.

Samuel A. M. Martin, P. Boudinot, C. Secombes, 2010, Molecular immunology.

A portrait of the immune response to proliferative kidney disease (PKD) in rainbow trout

C. Bailey, C. Secombes, C. Tafalla, 2020, Parasite immunology.

Starvation alters the liver transcriptome of the innate immune response in Atlantic salmon (Salmo salar)

D. Houlihan, C. Secombes, A. Douglas, 2010, BMC Genomics.

Toxicity of nitric oxide and peroxynitrite to bacterial pathogens of fish.

C. Secombes, A. Ellis, J. Campos-Pérez, 2000, Diseases of aquatic organisms.

The Function of Fish Cytokines

C. Secombes, J. Zou, 2016, Biology.

The gills are an important site of iNOS expression in rainbow trout Oncorhynchus mykiss after challenge with the Gram‐positive pathogen Renibacterium salmoninarum

C. Secombes, A. Ellis, P. Grabowski, 2000, Immunology.

Synthesis of lipoxins and other lipoxygenase products by macrophages from the rainbow trout, Oncorhynchus mykiss.

T. Pettitt, C. Secombes, A. Mallet, 1991, The Journal of biological chemistry.

Constitutive and LPS-induced gene expression in a macrophage-like cell line from the rainbow trout (Oncorhynchus mykiss).

C. Secombes, N. Bols, J. Zou, 2000, Developmental and comparative immunology.

Effects of temperature on Paramoeba perurans growth in culture and the associated microbial community

C. Collins, C. Secombes, O. Benedicenti, 2018, Parasitology.

Discovery of All Three Types in Cartilaginous Fishes Enables Phylogenetic Resolution of the Origins and Evolution of Interferons

C. Secombes, J. Zou, D. Macqueen, 2019, Front. Immunol..

Evolutionary history of the T cell receptor complex as revealed by small‐spotted catshark (Scyliorhinus canicula)

C. Secombes, D. Macqueen, H. Dooley, 2017, Developmental and comparative immunology.

Dietary lipid affects phospholipid fatty acid compositions, eicosanoid production and immune function in Atlantic salmon (Salmo salar).

J. G. Bell, J. Dick, C. Secombes, 1996, Prostaglandins, leukotrienes, and essential fatty acids.

Rainbow trout CK9, a CCL25-like ancient chemokine that attracts and regulates B cells and macrophages, the main antigen presenting cells in fish

C. Secombes, C. Tafalla, R. Castro, 2016, Oncotarget.

Effects of sewage sludge exposure on growth, feeding and protein synthesis of dab (Limanda limanda (L.))

R. Stagg, D. Houlihan, Mark John Costello, 1994 .

The effect of eicosanoids on rainbow trout, Oncorhynchus mykiss, leucocyte proliferation.

C. Secombes, A. Rowley, I. Ashton, 1994, Veterinary immunology and immunopathology.

CHAPTER 3 – The phylogeny of cytokines

P. Kaiser, C. Secombes, 2003 .

Recombinant interleukin-1 beta activates the hypothalamic-pituitary-interrenal axis in rainbow trout, Oncorhynchus mykiss.

C. Secombes, T. Pottinger, J. Holland, 2002, The Journal of endocrinology.

Two Types of TNF-α Exist in Teleost Fish: Phylogeny, Expression, and Bioactivity Analysis of Type-II TNF-α3 in Rainbow Trout Oncorhynchus mykiss

Ronggai Li, C. Secombes, Tiehui Wang, 2013, The Journal of Immunology.

Identification of an interferon antagonist protein encoded by segment 7 of infectious salmon anaemia virus.

V. Aspehaug, E. Biering, C. Secombes, 2006, Virus research.

Cloning of two rainbow trout nucleotide-binding oligomerization domain containing 2 (NOD2) splice variants and functional characterization of the NOD2 effector domains.

C. Secombes, P. Nie, M. Chang, 2011, Fish & shellfish immunology.

Role of autoantibodies in the autoimmune response to testis in rainbow trout (Salmo gairdneri).

I. Priede, C. Secombes, L. Laird, 1985, Immunology.

The A-layer influences the susceptibility of Aeromonas salmonicida to antibacterial peptides.

C. Secombes, M. Henry, 2000, Fish & shellfish immunology.

Origin and evolution of the RIG-I like RNA helicase gene family

C. Secombes, P. Nie, M. Chang, 2009, BMC Evolutionary Biology.

Leucocyte migration in rainbow trout (Oncorhynchus mykiss [Walbaum]): optimization of migration conditions and responses to host and pathogen (Diphyllobothrium dendriticum [Nitzsch]) derived chemoattractants.

C. Secombes, G. Sharp, A. Pike, 1991, Developmental and comparative immunology.

Distinct Differentiation Programs Triggered by IL-6 and LPS in Teleost IgM+ B Cells in The Absence of Germinal Centers

C. Secombes, D. Barreda, C. Tafalla, 2016, Scientific Reports.

Immunohistochemical localization of inflammatory cells and cell cycle proteins in the gills of Loma salmonae infected rainbow trout (Oncorhynchus mykiss).

C. Secombes, D. Speare, J. Zou, 2014, Fish & shellfish immunology.

ExpressedOrganization and Are Differentially Genes Exist in Fish That Differ in Gene Two Macrophage Colony-Stimulating Factor

M. Belosevic, C. Secombes, Tiehui Wang, 2008 .

Vaccination experiments in the gadoid haddock, Melanogrammus aeglefinus L., against the bacterial pathogen Vibrio anguillarum.

P. D. Smith, Y. Corripio-Miyar, C. Secombes, 2007, Veterinary immunology and immunopathology.

Fish Suppressors of Cytokine Signaling (SOCS): Gene Discovery, Modulation of Expression and Function

C. Secombes, S. Wadsworth, J. G. Vecino, 2011, Journal of signal transduction.

The effect of peptidoglycan enriched diets on antimicrobial peptide gene expression in rainbow trout (Oncorhynchus mykiss).

C. Secombes, S. Wadsworth, J. G. Vecino, 2013, Fish & shellfish immunology.

Type I IFNs That a Retroposition Event Gave Rise to Concept Coexist in Amphibians: Refuting the Intron-Containing Type I and Type III IFN

C. Secombes, J. Zou, Zhi-Hao Qi, 2010 .

Event Gave Rise to Type I Coexist in Amphibians : Refuting the Concept Intron-Containing Type I and Type III IFN

C. Secombes, P. Nie, Z. Qi, 2010 .

Long-term stimulation of trout head kidney cells with the cytokines MCSF, IL-2 and IL-6: gene expression dynamics.

Y. Corripio-Miyar, C. Secombes, J. Zou, 2012, Fish & shellfish immunology.

Identification and characterisation of TLR18-21 genes in Atlantic salmon (Salmo salar).

C. Secombes, J. Zou, B. Collet, 2014, Fish & shellfish immunology.

Identification and expression modulation of a C-type lectin domain family 4 homologue that is highly expressed in monocytes/macrophages in rainbow trout (Oncorhynchus mykiss).

Y. Corripio-Miyar, C. Secombes, J. Zou, 2016, Developmental and comparative immunology.

Biological Activity of Sea Bass (Dicentrarchus labrax L.) Recombinant Interleukin-1β

P. Bossù, F. Buonocore, G. Scapigliati, 2005, Marine Biotechnology.

A biologically active IL-1β derived peptide stimulates phagocytosis and bactericidal activity in rainbow trout, Oncorhynchus mykiss (Walbaum), head kidney leucocytes in vitro

C. Secombes, J. Zou, S. Peddie, 2002 .

The production and bioactivity of rainbow trout (Oncorhynchus mykiss) recombinant IL-1 beta.

G. Scapigliati, C. Secombes, N. Bols, 2001, Veterinary immunology and immunopathology.

Two Cathelicidin Genes Are Present in both Rainbow Trout (Oncorhynchus mykiss) and Atlantic Salmon (Salmo salar)

Yongan Zhang, C. Secombes, P. Nie, 2006, Antimicrobial Agents and Chemotherapy.

Enhancement of fish phagocyte activity

C. Secombes, 1994 .

The expression of immune-regulatory genes in rainbow trout, Oncorhynchus mykiss, during a natural outbreak of proliferative kidney disease (PKD)

L. Noble, C. Secombes, C. Jones, 2003, Parasitology.

Sequential development of the immune response in rainbow trout [Oncorhynchus mykiss (Walbaum, 1792)] to experimental plerocercoid infections of Diphyllobothrium dendriticum (Nitzsch, 1824)

C. Secombes, G. Sharp, A. Pike, 1992, Parasitology.

Isolation and characterisation of a putative interleukin 13 receptor α2 sequence from rainbow trout (Oncorhynchus mykiss)

C. Jones, L. Noble, E. Verspoor, 2001 .

The cytokine networks of adaptive immunity in fish.

C. Secombes, Tiehui Wang, 2013, Fish & shellfish immunology.

The evolution of IL-4 and IL-13 and their receptor subunits.

C. Secombes, Tiehui Wang, 2015, Cytokine.

Will advances in fish immunology change vaccination strategies?

C. Secombes, 2008, Fish & shellfish immunology.

An Mx1 promoter-reporter system to study interferon pathways in rainbow trout.

P. Boudinot, A. Benmansour, C. Secombes, 2004, Developmental and comparative immunology.

Cortisol modulates the induction of inflammatory gene expression in a rainbow trout macrophage cell line.

C. Secombes, J. Zou, R. Castro, 2011, Fish & shellfish immunology.

Distinct modes of action of CD40L and adaptive cytokines IL-2, IL-4/13, IL-10 and IL-21 on rainbow trout IgM+ B cells

C. Secombes, C. Tafalla, Tiehui Wang, 2020, Developmental and comparative immunology.

Immunoprophylaxis in fish by injection of mouse antibody genes

C. Secombes, E. Lorenzen, C. Cunningham, 2000, Nature Biotechnology.

Ontogeny of the immune system in carp (Cyprinus carpio L.). The appearance of antigenic determinants on lymphoid cells detected by mouse anti-carp thymocyte monoclonal antibodies.

E. Egberts, C. Secombes, W. B. Van Muiswinkel, 1983, Developmental and comparative immunology.

Induction of IL-22 protein and IL-22-producing cells in rainbow trout Oncorhynchus mykiss

C. Secombes, Tiehui Wang, Y. Carpio, 2019, Developmental and comparative immunology.

Cloning, expression analysis and bioactivity studies of rainbow trout (Oncorhynchus mykiss) interleukin-22.

C. Secombes, J. Zou, Tiehui Wang, 2011, Cytokine.

Molecular and expression analysis of an interferon-gamma-inducible guanylate-binding protein from rainbow trout (Oncorhynchus mykiss).

J. Leong, C. Secombes, B. Robertsen, 2006, Developmental and comparative immunology.

Expression of immune response genes in rainbow trout skin induced by Gyrodactylus derjavini infections.

C. Secombes, K. Buchmann, T. Lindenstrøm, 2004, Veterinary immunology and immunopathology.

Red mark syndrome in rainbow trout Oncorhynchus mykiss: investigation of immune responses in lesions using histology, immunohistochemistry and analysis of immune gene expression.

C. Secombes, T. Wang, E. Casadei, 2013, Fish & shellfish immunology.

GROWTH FACTORS OF LOWER VERTEBRATES: CHARACTERIZATION OF GOLDFISH ( Carassius auratus L.) MACROPHAGE COLONY STIMULATING FACTOR-1

M. Belosevic, C. Secombes, Tiehui Wang, 2007 .

Immunostimulatory CpG oligodeoxynucleotides stimulate expression of IL-1beta and interferon-like cytokines in rainbow trout macrophages via a chloroquine-sensitive mechanism.

C. Secombes, J. Zou, J. Jørgensen, 2001, Fish & shellfish immunology.

Immune gene expression in trout cell lines infected with the fish pathogenic oomycete Saprolegnia parasitica.

P. van West, Victoria L. Anderson, C. Secombes, 2012, Developmental and comparative immunology.

Atlantic salmon kidney (ASK) cells are an effective model to characterise interferon (IFN) and IFN-induced gene expression following salmonid alphavirus infection.

C. Secombes, H. Dooley, D. Munir, 2020, Fish & shellfish immunology.

Atlantic salmon post‐smolts adapted for a longer time to seawater develop an effective humoral and cellular immune response against Salmonid alphavirus

C. Secombes, L. Moore, G. Taranger, 2018, Fish & shellfish immunology.

Interferon response following infection with genetically similar isolates of viral haemorrhagic septicaemia virus (VHSV) exhibiting contrasting virulence in rainbow trout.

C. Secombes, M. Snow, B. Collet, 2011, Fish & shellfish immunology.

The rainbow trout (Oncorhynchus mykiss) interferon response in the ovary.

E. Chaves-Pozo, A. Cuesta, C. Secombes, 2010, Molecular immunology.

Infectious pancreatic necrosis virus suppresses type I interferon signalling in rainbow trout gonad cell line but not in Atlantic salmon macrophages.

C. Secombes, F. Acosta, A. Ellis, 2007, Fish & shellfish immunology.

Evolution of cytokine responses: IL-1beta directly affects intracellular Ca2+ concentration of teleost fish leukocytes through a receptor-mediated mechanism.

F. Buonocore, G. Scapigliati, C. Secombes, 2006, Cytokine.

Use of recombinant single-chain antibodies for prevention or treatment of diseases has been addressed in various studies including neutralization of viruses1,2 and toxins3, cancer immunotherapy4,5, and recently also in the form of DNA vaccines encoding anti-idiotype single-chain antibodies6. At cell

C. Secombes, E. Lorenzen, C. Cunningham, 2017 .

The immune response of carp, Cyprinus carpio L., following injection of antigen‐antibody complexes

C. Secombes, J. Resink, 1984 .

Use of a genetically attenuated strain of Aeromonas salmonicida to vaccinate salmonid fish

T. Foster, C. Secombes, A. Devoy, 1996, Aquaculture International.

Factors influencing the clearance of a genetically attenuated (ΔaroA) strain of Aeromonas salmonicida from rainbow trout Oncorhynchus mykiss

C. Secombes, M. J. Marsden, E. Collins, 1996 .

Cellular requirements for lymphokine secretion by rainbow trout Salmo gairdneri leucocytes.

C. Secombes, S. Graham, 1990, Developmental and comparative immunology.

Four selenoprotein P genes exist in salmonids: Analysis of their origin and expression following Se supplementation and bacterial infection

Samuel A. M. Martin, C. Secombes, Tiehui Wang, 2018, PloS one.

What's new in fish cytokine research?

C. Secombes, 2016, Fish & shellfish immunology.

Re-examination of the rainbow trout (Oncorhynchus mykiss) immune response to flagellin: Yersinia ruckeri flagellin is a potent activator of acute phase proteins, anti-microbial peptides and pro-inflammatory cytokines in vitro.

C. Secombes, Tiehui Wang, E. Wangkahart, 2016, Developmental and comparative immunology.

Expression kinetics of interferon and interferon-induced genes in Atlantic salmon (Salmo salar) following infection with infectious pancreatic necrosis virus and infectious salmon anaemia virus.

C. Secombes, M. Snow, A. Ellis, 2007, Fish & shellfish immunology.

Expression of genes related to the early immune response in rainbow trout (Oncorhynchus mykiss) after viral haemorrhagic septicemia virus (VHSV) infection.

J. coll, C. Secombes, C. Tafalla, 2005, Developmental and comparative immunology.

Infectious pancreatic necrosis virus (IPNV) recombinant viral protein 1 (VP1) and VP2-Flagellin fusion protein elicit distinct expression profiles of cytokines involved in type 1, type 2, and regulatory T cell response in rainbow trout (Oncorhynchus mykiss).

C. Secombes, A. Sandino, M. Imarai, 2022, Fish & shellfish immunology.

The search for the IFN-gamma receptor in fish: Functional and expression analysis of putative binding and signalling chains in rainbow trout Oncorhynchus mykiss.

C. Secombes, P. Nie, K. Thompson, 2009, Developmental and comparative immunology.

Phylogeny of vertebrate cytokines.

C. Secombes, J. Zou, K. Laing, 2001, Advances in experimental medicine and biology.

Proliferative responses of rainbow trout, Oncorhynchusmykiss, T and B cells to antigens of Aeromonas salmonicida

C. Secombes, S. H. Hamdani, M. J. Marsden, 1995 .

In vitro activation of rainbow trout macrophages stimulates inhibition of Renibacterium salmoninarum growth concomitant with augmented generation of respiratory burst products

C. Secombes, L. Hardie, A. Ellis, 1996 .

DNA vaccination against viral haemorrhagic septicaemia (VHS) in rainbow trout: size, dose, route of injection and duration of protection-early protection correlates with Mx expression.

C. Secombes, A. Ellis, B. Collet, 2003, Fish & shellfish immunology.

Effects of dietary fatty acids on eicosanoid-generating capacity, fatty acid composition and chemotactic activity of rainbow trout (Oncorhynchus mykiss) leucocytes.

C. Secombes, A. Rowley, S. Barrow, 1994, Biochimica et biophysica acta.

Analysis of adipose tissue immune gene expression after vaccination of rainbow trout with adjuvanted bacterins reveals an association with side effects

C. Secombes, A. Douglas, Tiehui Wang, 2017, Molecular immunology.

Quantification of Atlantic salmon type-I interferon using an Mx1 promoter reporter gene assay.

C. Secombes, B. Collet, J. Jørgensen, 2004, Fish & shellfish immunology.

Identification of C3a Receptors in : The First Xenopus Rainbow Trout and Characterization of a C3a Receptor in

C. Secombes, L. Tort, Tiehui Wang, 2022 .

Dissecting the immune pathways stimulated following injection vaccination of rainbow trout (Oncorhynchus mykiss) against enteric redmouth disease (ERM).

C. Secombes, Tiehui Wang, E. Wangkahart, 2017, Fish & shellfish immunology.

Identification of the salmonid IL-17A/F1a/b, IL-17A/F2b, IL-17A/F3 and IL-17N genes and analysis of their expression following in vitro stimulation and infection

C. Secombes, Yousheng Jiang, Tiehui Wang, 2015, Immunogenetics.

Interleukin-1 in fish

C. Secombes, C. Cunningham, J. Zou, 1999 .

Effects of transforming growth factor beta 1 on rainbow trout Oncorhynchus mykiss macrophage respiratory burst activity.

S. Jang, C. Secombes, L. Hardie, 1994, Developmental and comparative immunology.

Action in pairs

C. Secombes, H. Deng, 2014, Virulence.

Cytokine expression in the intestine of rainbow trout (Oncorhynchus mykiss) during infection with Aeromonas salmonicida.

C. Secombes, S. Wadsworth, I. Mulder, 2007, Fish & shellfish immunology.

An assessment of immunostimulants as Mx inducers in Atlantic salmon (Salmo salar L.) parr and the effect of temperature on the kinetics of Mx responses.

C. Secombes, I. Salinas, K. Lockhart, 2004, Fish & shellfish immunology.

Cytokine genes in fish

C. Secombes, C. Cunningham, J. Zou, 1999 .

Host—Pathogen Interactions in Salmonids

C. Secombes, G. Olivier, 1997 .

Involvement of two microRNAs in the early immune response to DNA vaccination against a fish rhabdovirus.

C. Secombes, J. Zou, N. Lorenzen, 2015, Vaccine.

Growth Factors of Lower Vertebrates

M. Belosevic, C. Secombes, Tiehui Wang, 2007, Journal of Biological Chemistry.

Immune response modulation upon sequential heterogeneous co‐infection with Tetracapsuloides bryosalmonae and VHSV in brown trout (Salmo trutta)

N. Taylor, C. Secombes, S. Feist, 2019, Fish & shellfish immunology.

Characterization of BAFF and APRIL subfamily receptors in rainbow trout (Oncorhynchus mykiss). Potential role of the BAFF / APRIL axis in the pathogenesis of proliferative kidney disease

C. Secombes, C. Tafalla, J. Holland, 2017, PloS one.

Saprolegnia—Fish Interactions

P. West, Victoria L. Anderson, C. Secombes, 2008 .

The Fish Pathogen Yersinia ruckeri Produces Holomycin and Uses an RNA Methyltransferase for Self-resistance

C. Secombes, M. Jaspars, H. Deng, 2013, The Journal of Biological Chemistry.

Molecular characterization and expression analysis of the putative interleukin 6 receptor (IL-6Rα and glycoprotein-130) in rainbow trout (Oncorhynchus mykiss): Salmonid IL-6Rα possesses a polymorphic N-terminal Ig domain with variable numbers of two repeats

C. Secombes, Tiehui Wang, M. Monte, 2012, Immunogenetics.

The role of reactive oxygen species in the killing of the bacterial fish pathogen Aeromonas salmonicida by rainbow trout macrophages

C. Secombes, G. Sharp, G. J. E. Sharp, 1993 .

The role of phagocytes in the protective mechanisms of fish

C. Secombes, T. C. Fletcher, 1992 .

Isolation of salmonid macrophages and analysis of their killing activity

C. Secombes, 1990 .

Activation of rainbow trout macrophages

C. Secombes, S. Chung, 1987 .

CpG oligodeoxynucleotides stimulate immune cell proliferation but not specific antibody production in rainbow trout (Oncorhynchus mykiss).

C. Secombes, B. Collet, J. Holland, 2004, Veterinary immunology and immunopathology.

The effect of dietary vitamin A on the immunocompetence of Atlantic salmon (Salmo salar L.)

D. Houlihan, C. Secombes, T. C. Fletcher, 1994, Fish Physiology and Biochemistry.

B cell receptor accessory molecule CD79α: Characterisation and expression analysis in a cartilaginous fish, the spiny dogfish (Squalus acanthias)

Ronggai Li, C. Secombes, J. Zou, 2013, Fish & shellfish immunology.

The immune response of wild rainbow trout, Salmo gairdneri Richardson, to naturally acquired plerocercoid infections of Diphyllobothrium dendriticum (Nitzsch, 1824) and D. ditremum (Creplin, 1825)

C. Secombes, G. Sharp, A. Pike, 1989 .

Analysis of events occurring within teleost macrophages during the respiratory burst

C. Secombes, S. Chung, 1988 .

Characterization of cytosolic glutathione peroxidase and phospholipid-hydroperoxide glutathione peroxidase genes in rainbow trout (Oncorhynchus mykiss) and their modulation by in vitro selenium exposure.

J. Feldmann, C. Secombes, M. Page, 2013, Aquatic toxicology.

Transcriptomic and physiological responses to fishmeal substitution with plant proteins in formulated feed in farmed Atlantic salmon (Salmo salar)

C. Secombes, L. Tacchi, R. Bickerdike, 2012, BMC Genomics.

Cytokines in fish: an update

C. Secombes, L. Hardie, G. Daniels, 1996 .

In vitro studies on the regulation of rainbow trout (Oncorhynchus mykiss) macrophage respiratory burst activity.

A. Figueras, C. Secombes, B. Novoa, 1996, Developmental and comparative immunology.

The effect of vitamin E on the immune response of the Atlantic salmon (Salmo salar L.).

C. Secombes, L. Hardie, T. C. Fletcher, 1991 .

Transcriptomic responses to functional feeds in Atlantic salmon (Salmo salar).

C. Secombes, A. Douglas, L. Tacchi, 2011, Fish & shellfish immunology.

Molecular characterisation of sea bream (Sparus aurata) transforming growth factor beta1.

A. Figueras, C. Secombes, J. Castrillo, 2003, Fish & shellfish immunology.

Phylogeny of cytokines: molecular cloning and expression analysis of sea bass Dicentrarchus labrax interleukin-1beta.

F. Buonocore, G. Scapigliati, C. Secombes, 2001, Fish & shellfish immunology.

Fish immune responses to experimental and natural infection with helminth parasites

C. Secombes, L. Chappell, 1996 .

The effect of glycyrrhizin on rainbow trout, Oncorhynchus mykiss (Walbaum), leucocyte responses

S. Jang, C. Secombes, M. Choi, 1995 .

Comparative studies on the immune system of fishes and amphibians: antigen localization in the carp Cyprinus carpio L.

M. Manning, C. Secombes, 1980 .

Expression of immune genes in turbot (Scophthalmus maximus) fed a nucleotide-supplemented diet

C. Secombes, S. Wadsworth, C. Burrells, 2003 .

The innate and adaptive immune system of fish

C. Secombes, Tiehui Wang, 2012 .

Effects of temperature on amoebic gill disease development: Does it play a role?

C. Collins, C. Secombes, T. Pottinger, 2019, Journal of fish diseases.

S0031182018001798jra 533..542

C. Collins, C. Secombes, O. Benedicenti, 2019 .

Gyrodactylus derjavini infection elicits IL-1beta expression in rainbow trout skin.

C. Secombes, K. Buchmann, T. Lindenstrøm, 2003, Fish & shellfish immunology.

Increased parasite resistance of greater amberjack (Seriola dumerili Risso 1810) juveniles fed a cMOS supplemented diet is associated with upregulation of a discrete set of immune genes in mucosal tissues

C. Secombes, M. Izquierdo, D. Montero, 2019, Fish & shellfish immunology.

Distinct response of immune gene expression in peripheral blood leucocytes modulated by bacterin vaccine candidates in rainbow trout Oncorhynchus mykiss: A potential in vitro screening and batch testing system for vaccine development in aquaculture.

C. Secombes, Yousheng Jiang, Tiehui Wang, 2019, Fish & shellfish immunology.

Comparative study of the effects of Montanide™ ISA 763A VG and ISA 763B VG adjuvants on the immune response against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus)

C. Secombes, Tiehui Wang, P. Srisapoome, 2023, Fish & Shellfish Immunology.

Effect of a yeast-cell-wall glucan on the bactericidal activity of rainbow trout macrophages

C. Secombes, B. Robertsen, J. Jørgensen, 1993 .

A putative serine protease, SpSsp1, from Saprolegnia parasitica is recognised by sera of rainbow trout, Oncorhynchus mykiss

P. van West, Victoria L. Anderson, Stephan Wawra, 2014, Fungal biology.

New insights into animal pathogenic oomycetes.

P. van West, Victoria L. Anderson, C. Secombes, 2008, Trends in microbiology.

Studies on the Use of Flagellin as an Immunostimulant and Vaccine Adjuvant in Fish Aquaculture

C. Secombes, Tiehui Wang, E. Wangkahart, 2019, Front. Immunol..

Characterization of a C3a Receptor in Rainbow Trout and Xenopus: The First Identification of C3a Receptors in Nonmammalian Species1

C. Secombes, L. Tort, J. Hansen, 2005, The Journal of Immunology.

Nonmammalian Species Identification of C 3 a Receptors in : The First Xenopus Rainbow Trout and Characterization of a C 3 a Receptor in Lluis Tort

C. Secombes, L. Tort, J. Hansen, 2005 .

Host-targeting protein 1 (SpHtp1) from the oomycete Saprolegnia parasitica translocates specifically into fish cells in a tyrosine-O-sulphate–dependent manner

S. Whisson, P. van West, Stephan Wawra, 2012, Proceedings of the National Academy of Sciences.

The putative RxLR effector protein SpHtp1 from the fish pathogenic oomycete Saprolegnia parasitica is translocated into fish cells.

P. van West, Victoria L. Anderson, Stephan Wawra, 2010, FEMS microbiology letters.

Effect of temperature on macrophage activation and the production of macrophage activating factor by rainbow trout (Oncorhynchus mykiss) leucocytes.

C. Secombes, L. Hardie, T. C. Fletcher, 1994, Developmental and comparative immunology.

A review of CpGs and their relevance to aquaculture.

C. Secombes, A. Carrington, 2006, Veterinary immunology and immunopathology.

Environmental and physiological factors shape the gut microbiota of Atlantic salmon parr (Salmo salar L.)

C. Secombes, S. Martin, C. Dehler, 2017, Aquaculture.

Localization of immune complexes and heat-aggregated immunoglobulin in the carp Cyprinus carpio L.

M. Manning, C. Secombes, A. Ellis, 1982, Immunology.

Rainbow trout interleukin-2: cloning, expression and bioactivity analysis.

C. Secombes, W. Davidson, J. Zou, 2009, Fish & shellfish immunology.

Revisiting the Teleost Thymus: Current Knowledge and Future Perspectives

C. Secombes, F. Gúzman, M. Imarai, 2020, Biology.

Lysozyme and antiprotease activity in the lesser octopus Eledone cirrhosa (Lam.) (Cephalopoda).

S. Malham, C. Secombes, N. W. Runham, 1998, Developmental and comparative immunology.

Cytokines and innate immunity of fish.

C. Secombes, C. Cunningham, J. Zou, 2001, Developmental and comparative immunology.

Generation of primary monocyte-like cultures from rainbow trout head kidney leukocytes.

J. Stafford, M. Belosevic, C. Secombes, 2001, Developmental and comparative immunology.

Evolution of interleukin-1β

B. Munday, C. Secombes, C. Cunningham, 2002 .

Investigation of factors influencing the ability ofRenibacterium salmoninarumto stimulate rainbow trout macrophage respiratory burst activity

C. Secombes, A. Ellis, J. Campos-Pérez, 1997 .

Individual Monitoring of Immune Response in Atlantic Salmon Salmo salar following Experimental Infection with Infectious Salmon Anaemia Virus (ISAV)

C. Collins, C. Secombes, B. Collet, 2015, PloS one.

Identification and Bioactivities of IFN-γ in Rainbow Trout Oncorhynchus mykiss: The First Th1-Type Cytokine Characterized Functionally in Fish1

C. Secombes, Y. Yoshiura, N. Bols, 2005, The Journal of Immunology.

Modulation of local and systemic immune responses in brown trout (Salmo trutta) following exposure to Myxobolus cerebralis.

C. Secombes, M. El-Matbouli, M. Saleh, 2020, Fish & shellfish immunology.

STAT3/SOCS3 axis contributes to the outcome of salmonid whirling disease

C. Secombes, M. El-Matbouli, M. Saleh, 2020, PloS one.

A novel minicollagen gene links cnidarians and myxozoans

H. Hartikainen, C. Secombes, B. Okamura, 2011, Proceedings of the Royal Society B: Biological Sciences.

Cercariae and diplostomules of Diplostomum spathaceum (Digenea) elicit an immune response in rainbow trout, Salmo gairdneri Richardson

S. Whyte, C. Secombes, L. Chappell, 1987 .

Tetracapsuloides bryosalmonae abundance in river water.

H. Hartikainen, C. Secombes, B. Okamura, 2017, Diseases of aquatic organisms.

Comparative transcriptomics and host-specific parasite gene expression profiles inform on drivers of proliferative kidney disease

H. Hartikainen, C. Secombes, B. Okamura, 2020, Scientific Reports.

Dysregulation of B Cell Activity During Proliferative Kidney Disease in Rainbow Trout

C. Secombes, C. Tafalla, Aitor G. Granja, 2018, Front. Immunol..

Molecular characterization and expression analysis of four fish‐specific CC chemokine receptors CCR4La, CCR4Lc1, CCR4Lc2 and CCR11 in rainbow trout (Oncorhynchus mykiss)

C. Secombes, P. Nie, Yousheng Jiang, 2017, Fish & shellfish immunology.

Identification and expression analysis of an atypical chemokine receptor-2 (ACKR2)/CC chemokine binding protein-2 (CCBP2) in rainbow trout (Oncorhynchus mykiss).

C. Secombes, P. Nie, Yousheng Jiang, 2015, Fish & shellfish immunology.

Sequence and expression analysis of rainbow trout CXCR2, CXCR3a and CXCR3b aids interpretation of lineage-specific conversion, loss and expansion of these receptors during vertebrate evolution

Ronggai Li, C. Secombes, P. Nie, 2014, Developmental and comparative immunology.

Immune gene expression profiling of Proliferative Kidney Disease in rainbow trout Oncorhynchus mykiss reveals a dominance of anti-inflammatory, antibody and T helper cell-like activities

C. Secombes, Tiehui Wang, J. Holland, 2013, Veterinary Research.

Identification of IL-34 in teleost fish: differential expression of rainbow trout IL-34, MCSF1 and MCSF2, ligands of the MCSF receptor.

C. Secombes, M. Sakai, Tiehui Wang, 2013, Molecular immunology.

Cloning and Characterization of Rainbow Trout Interleukin-17A/F2 (IL-17A/F2) and IL-17 Receptor A: Expression during Infection and Bioactivity of Recombinant IL-17A/F2

C. Secombes, J. Zou, Tiehui Wang, 2012, Infection and Immunity.

Sequence and expression analysis of two T helper master transcription factors, T-bet and GATA3, in rainbow trout Oncorhynchus mykiss and analysis of their expression during bacterial and parasitic infection.

Samuel A. M. Martin, C. Secombes, S. Martin, 2010, Fish & shellfish immunology.

Interaction between rainbow trout macrophages and Renibacterium salmoninarum in vitro

C. Secombes, A. Ellis, J. Barja, 1993 .

An insight into piscidins: The discovery, modulation and bioactivity of greater amberjack, Seriola dumerili, piscidin.

C. Secombes, D. Montero, S. Torrecillas, 2019, Molecular immunology.

Studies on the infectivity of Diplostomum spathaceum in rainbow trout (Oncorhynchus mykiss)

S. Whyte, C. Secombes, L. Chappell, 1991, Journal of Helminthology.

Antigen-induced release of macrophage activating factor from rainbow trout Oncorhynchus mykiss leucocytes.

C. Secombes, M. J. Marsden, D. Cox, 1994, Veterinary immunology and immunopathology.

Effective isolation of GALT cells: Insights into the intestine immune response of rainbow trout (Oncorhynchus mykiss) to different bacterin vaccine preparations.

C. Secombes, Tiehui Wang, Ahmed Attaya, 2020, Fish & shellfish immunology.

Susceptibility of strains of Aeromonas salmonicida to killing by cell‐free generated superoxide anion

C. Secombes, J. Karczewski, G. Sharp, 1991 .

Gene expression analysis of the innate immune system during early rearing and weaning of meagre (Argyrosomus regius).

K. Andree, C. Secombes, E. Gisbert, 2019, Fish & shellfish immunology.

Gene expression profiling in naïve and vaccinated rainbow trout after Yersinia ruckeri infection: insights into the mechanisms of protection seen in vaccinated fish.

C. Secombes, Tiehui Wang, N. Harun, 2011, Vaccine.

Molecular cloning and characterization of interferon regulatory factors 4 and 8 (IRF-4 and IRF-8) in rainbow trout, Oncorhynchus mykiss.

C. Secombes, B. Collet, Tiehui Wang, 2010, Fish & shellfish immunology.

Transcriptome response following administration of a live bacterial vaccine in Atlantic salmon (Salmo salar).

D. Houlihan, C. Secombes, S. Martin, 2006, Molecular immunology.

Cloning and expression analysis of rainbow trout Oncorhynchus mykiss interferon regulatory factor 1 and 2 (IRF-1 and IRF-2).

D. Mazzoni, I. Hirono, T. Aoki, 2003, Developmental and comparative immunology.

Phagocytosis by haemocytes from the Lesser Octopus Eledone cirrhosa

S. Malham, C. Secombes, N. W. Runham, 1997 .

Sequence and Expression Analysis of Interferon Regulatory Factor 10 (IRF10) in Three Diverse Teleost Fish Reveals Its Role in Antiviral Defense

Pin Nie, Jun Zou, Tiehui Wang, 2016, PloS one.

Distinctive Expansion of Potential Virulence Genes in the Genome of the Oomycete Fish Pathogen Saprolegnia parasitica

B. Snel, B. Haas, J. Levin, 2013, PLoS genetics.

Generation and characterisation of monoclonal antibodies against rainbow trout, Oncorhynchus mykiss, leucocytes.

C. Secombes, G. Rainger, A. Rowley, 1997, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

Cardiac pathological changes of Atlantic salmon (Salmo salar L.) affected with heart and skeletal muscle inflammation (HSMI).

K. Skjødt, C. Secombes, J. Zou, 2012, Fish & shellfish immunology.

Analysis of lymphocyte heterogeneity in carp, Cyprinus carpio L., using monoclonal antibodies

J. Wellink, E. Egberts, C. Secombes, 1983 .

A live (delta aroA) Aeromonas salmonicida vaccine for furunculosis preferentially stimulates T-cell responses relative to B-cell responses in rainbow trout (Oncorhynchus mykiss)

T. Foster, C. Secombes, L. Vaughan, 1996, Infection and immunity.

Teleost fish interferons and their role in immunity.

C. Secombes, J. Zou, 2011, Developmental and comparative immunology.

Identification of an interferon gamma homologue in Fugu, Takifugu rubripes.

C. Secombes, M. Ototake, Y. Yoshiura, 2004, Fish & shellfish immunology.

NADPH oxidase-like activity in rainbow trout Oncorhynchus mykiss (Walbaum) macrophages.

C. Secombes, A. Cross, R. García, 1992, Developmental and comparative immunology.

CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell–like Populations and Diverse Mononuclear Phagocytes

Athanasiadis, A. Cvejic, C. Secombes, 2016 .

Cloning and expression analysis of the transforming growth factor-beta receptors type 1 and 2 in the rainbow trout Oncorhynchus mykiss.

C. Secombes, S. Wadsworth, Tiehui Wang, 2012, Developmental and comparative immunology.

Two copies of the genes encoding the subunits of putative interleukin (IL)-4/IL-13 receptors, IL-4Rα, IL-13Rα1 and IL-13Rα2, have been identified in rainbow trout (Oncorhynchus mykiss) and have complex patterns of expression and modulation

Samuel A. M. Martin, C. Secombes, Wen-shu Huang, 2011, Immunogenetics.

Two Macrophage Colony-Stimulating Factor Genes Exist in Fish That Differ in Gene Organization and Are Differentially Expressed12

M. Belosevic, C. Secombes, Tiehui Wang, 2008, The Journal of Immunology.

Molecular cloning and expression analysis of tumour necrosis factor-alpha in amoebic gill disease (AGD)-affected Atlantic salmon (Salmo salar L.).

G. Scapigliati, C. Secombes, B. Nowak, 2007, Fish & shellfish immunology.

Identification and expression analysis of lymphotoxin-beta like homologues in rainbow trout Oncorhynchus mykiss.

C. Secombes, R. Savan, J. Zou, 2006, Molecular immunology.

Cloning of the Atlantic salmon (Salmo salar) IL-1 receptor associated protein.

C. Stansberg, C. Secombes, S. Subramaniam, 2005, Fish & shellfish immunology.

Molecular identification and expression analysis of tumor necrosis factor in channel catfish (Ictalurus punctatus).

C. Secombes, L. Clem, N. Miller, 2003, Developmental and comparative immunology.

Cloning and characterisation of a putative ST2L homologue from Atlantic salmon (Salmo salar).

C. Stansberg, C. Secombes, S. Subramaniam, 2003, Fish & shellfish immunology.

Cloning of a Salmo salar interleukin-1 receptor-like cDNA.

C. Stansberg, C. Secombes, S. Subramaniam, 2002, Developmental and comparative immunology.

Cloning and expression of a putative common cytokine receptor gamma chain (γC) gene in rainbow trout (Oncorhynchus mykiss)

C. Secombes, Tiehui Wang, 2001 .

Cloning and expression analysis of rainbow trout Oncorhynchus mykiss tumour necrosis factor‐α

I. Hirono, T. Aoki, C. Secombes, 2001 .

Homologs of CD83 from Elasmobranch and Teleost Fish12

M. Flajnik, Y. Ohta, C. Secombes, 2004, The Journal of Immunology.

Ontogeny and modulation after PAMPs stimulation of β-defensin, hepcidin, and piscidin antimicrobial peptides in meagre (Argyrosomus regius).

K. Andree, C. Secombes, N. Duncan, 2017, Fish & shellfish immunology.

Discovery of multiple beta-defensin like homologues in teleost fish.

C. Secombes, J. Zou, C. Mercier, 2007, Molecular immunology.

Molecular and Functional Characterization of IL-15 in Rainbow Trout Oncorhynchus mykiss: A Potent Inducer of IFN-γ Expression in Spleen Leukocytes12

C. Secombes, J. Zou, Tiehui Wang, 2007, The Journal of Immunology.

Expression in Spleen Leukocytes g A Potent Inducer of IFN- mykiss: Oncorhynchus of IL-15 in Rainbow Trout Molecular and Functional Characterization

C. Secombes, Tiehui Wang, J. Holland, 2007 .

Ancient Cytokine Interleukin 15-Like (IL-15L) Induces a Type 2 Immune Response

C. Secombes, Takuya Yamaguchi, J. M. Dijkstra, 2020, Frontiers in Immunology.

The first functional characterization of ancient interleukin-15-like (IL-15L) reveals shared and distinct functions of the IL-2, -15 and -15L family cytokines

C. Secombes, Takuya Yamaguchi, J. M. Dijkstra, 2019, bioRxiv.

Identification of a Second Group of Type I IFNs in Fish Sheds Light on IFN Evolution in Vertebrates1

C. Secombes, J. Zou, C. Tafalla, 2007, The Journal of Immunology.

Vertebrates IFNs in Fish Sheds Light on IFN Evolution in Identification of a Second Group of Type I

C. Secombes, J. Zou, C. Tafalla, 2007 .

Sequencing and expression of the second allele of the interleukin-1beta1 gene in rainbow trout (Oncorhynchus mykiss): identification of a novel SINE in the third intron.

C. Secombes, N. Bols, J. Zou, 2004, Fish & shellfish immunology.

Advances in greater amberjack (Seriola dumerili) research: the DIVERSIFY project

Izquierdo, P. Katharios, C. Secombes, 2016 .

Air-classified faba bean protein concentrate is efficiently utilized as a dietary protein source by post-smolt Atlantic salmon (Salmo salar)

D. Tocher, C. Secombes, K. Ruohonen, 2016 .

Atlantic salmon (Salmo salar) parr as a model to predict the optimum inclusion of air classified faba bean protein concentrate in feeds for seawater salmon

J. G. Bell, D. Tocher, C. Secombes, 2015 .

Cloning and expression analysis of the mitochondrial ubiquitin ligase activator of NF-κB (MULAN) in Atlantic salmon (Salmo salar).

C. Secombes, L. Tacchi, R. Bickerdike, 2011, Molecular immunology.

The promoter for the Interferon Regulatory Factor (IRF)-2 in the rainbow trout Oncorhynchus mykiss: cloning and reporter gene activity.

C. Secombes, B. Collet, Colin McDonald, 2003, Fish & shellfish immunology.

Characterization and expression analysis of Th-POK from the Japanese pufferfish, Takifugu rubripes.

C. Secombes, M. Sakai, T. Kono, 2013, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Identification and characterization of the transcription factors involved in T‐cell development, t‐bet, stat6 and foxp3, within the zebrafish, Danio rerio

C. Secombes, S. Mitra, S. Bird, 2010, The FEBS journal.

Characterization and expression analysis of an interleukin‐7 homologue in the Japanese pufferfish, Takifugu rubripes

C. Secombes, R. Savan, M. Sakai, 2008, The FEBS journal.

Characterisation and expression analysis of interleukin 2 (IL-2) and IL-21 homologues in the Japanese pufferfish, Fugu rubripes, following their discovery by synteny

C. Secombes, J. M. Dijkstra, J. Zou, 2005, Immunogenetics.

Two interleukin-17C-like genes exist in rainbow trout Oncorhynchus mykiss that are differentially expressed and modulated.

C. Secombes, Tiehui Wang, S. Martin, 2010, Developmental and comparative immunology.

Immunohistochemical examination of immune cells in adipose tissue of rainbow trout (Oncorhynchus mykiss) following intraperitoneal vaccination

J. Ben Arous, C. Secombes, A. Alnabulsi, 2019, Fish & shellfish immunology.

Characterisation and expression analysis of the rainbow trout (Oncorhynchus mykiss) homologue of the human dendritic cell marker CD208/lysosomal associated membrane protein 3.

Y. Corripio-Miyar, C. Secombes, J. Zou, 2012, Developmental and comparative immunology.

Transforming growth factor-β1b: a second TGF-β1 paralogue in the rainbow trout (Oncorhynchus mykiss) that has a lower constitutive expression but is more responsive to immune stimulation.

C. Secombes, S. Wadsworth, J. G. Vecino, 2013, Fish & shellfish immunology.

Differential expression of two tumor necrosis factor genes in rainbow trout, Oncorhynchus mykiss.

G. Soma, I. Hirono, T. Aoki, 2002, Developmental and comparative immunology.

Functionally in Fish First Th 1-Type Cytokine Characterized : The Oncorhynchus mykiss Rainbow Trout in γ Identification and Bioactivities of IFN-Secombes

C. Secombes, Y. Yoshiura, N. Bols, 2005 .

Identification and expression analysis of an IL-18 homologue and its alternatively spliced form in rainbow trout (Oncorhynchus mykiss).

C. Secombes, N. Bols, J. Zou, 2004, European journal of biochemistry.

Analysis and characterisation of IL-1beta processing in rainbow trout, Oncorhynchus mykiss.

C. Secombes, N. Bols, J. Zou, 2004, Fish & shellfish immunology.

Factors influencing the expression of interleukin-1 beta in cultured rainbow trout (Oncorhynchus mykiss) leucocytes.

O. Pleguezuelos, C. Secombes, C. Cunningham, 2000, Developmental and comparative immunology.

Human tumor necrosis factor alpha influences rainbow trout Oncorhynchus mykiss leucocyte responses.

C. Secombes, L. Hardie, L. Chappell, 1994, Veterinary immunology and immunopathology.

Towards selective breeding of Atlantic salmon for sea louse resistance: approaches to identify trait markers.

C. Jones, L. Noble, E. Verspoor, 2002, Pest management science.

Characterisation of rainbow trout peripheral blood leucocytes prepared by hypotonic lysis of erythrocytes, and analysis of their phagocytic activity, proliferation and response to PAMPs and proinflammatory cytokines

C. Secombes, M. Imarai, Tiehui Wang, 2018, Developmental and comparative immunology.

Cloning and functional characterisation of the interleukin-1 beta 1 promoter of rainbow trout (Oncorhynchus mykiss).

C. Secombes, C. Cunningham, J. Zou, 2002, Biochimica et biophysica acta.

Promoter paper Cloning and functional characterisation of the interleukin-1h1 promoter of rainbow trout (Oncorhynchus mykiss) $

C. Secombes, C. Cunningham, J. Zou, 2002 .

Identification and analysis of an interleukin 8-like molecule in rainbow trout Oncorhynchus mykiss.

I. Hirono, T. Aoki, C. Secombes, 2002, Developmental and comparative immunology.

The effect of intraperitoneally administered recombinant IL-1beta on immune parameters and resistance to Aeromonas salmonicida in the rainbow trout (Oncorhynchus mykiss).

C. Secombes, J. Zou, Suhee Hong, 2003, Developmental and comparative immunology.

Cloning and expression analysis of rainbow trout Oncorhynchus mykiss tumour necrosis factor-alpha.

I. Hirono, T. Aoki, C. Secombes, 2001, European journal of biochemistry.

Cloning, sequencing, and analysis of expression of a second IL-1β gene in rainbow trout (Oncorhynchus mykiss)

O. Pleguezuelos, C. Secombes, C. Cunningham, 2000, Immunogenetics.

Trout CC chemokines: comparison of their sequences and expression patterns.

C. Secombes, K. Laing, 2004, Molecular immunology.

Individual monitoring of immune responses in rainbow trout after cohabitation and intraperitoneal injection challenge with Yersinia ruckeri.

C. Secombes, B. Collet, K. Urquhart, 2016, Fish & shellfish immunology.

Phylogenetic analysis of vertebrate CXC chemokines reveals novel lineage specific groups in teleost fish.

P. Xie, Y. Corripio-Miyar, C. Secombes, 2013, Developmental and comparative immunology.

The interleukins of fish.

C. Secombes, Tiehui Wang, T. Wang, 2011, Developmental and comparative immunology.

Developmental and Comparative Immunology

C. Secombes, Tiehui Wang, S. Bird, 2011 .

Fish cytokines: discovery, activities and potential applications.

J. Meseguer, C. Secombes, A. García-Ayala, 2008 .

The cytokine IL-1β from the crocodile icefish Chionodraco hamatus (Perciformes: Channichthyidae)

F. Buonocore, G. Scapigliati, F. Paderi, 2006, Polar Biology.

Rainbow trout (Oncorhynchus mykiss) recombinant IL-1beta and derived peptides induce migration of head-kidney leucocytes in vitro.

C. Secombes, C. Cunningham, J. Zou, 2001, Fish & shellfish immunology.

Identification, molecular characterization and functional analysis of interleukin (IL)-2 and IL-2like (IL-2L) cytokines in sea bass (Dicentrarchus labrax L.).

M. Gerdol, F. Buonocore, A. Pallavicini, 2019, Cytokine.

Evolution of Th2 responses: characterization of IL-4/13 in sea bass (Dicentrarchus labrax L.) and studies of expression and biological activity

M. Gerdol, F. Buonocore, A. Pallavicini, 2017, Scientific Reports.

Directional responses following recombinant cytokine stimulation of rainbow trout (Oncorhynchus mykiss) RTS-11 macrophage cells as revealed by transcriptome profiling

D. Houlihan, C. Secombes, J. Zou, 2007, BMC Genomics.

Cloning and expression of the first nonmammalian interleukin‐11 gene in rainbow trout Oncorhynchus mykiss

C. Secombes, N. Bols, Tiehui Wang, 2005, The FEBS journal.

Expression in Escherchia coli and Purification of Sea Bass (Dicentrarchus labrax) Interleukin 1β, a Possible Immunoadjuvant in Aquaculture

F. Buonocore, G. Scapigliati, M. Forlenza, 2003, Marine Biotechnology.

The rainbow trout Oncorhynchus mykiss interleukin‐1β gene has a different organization to mammals and undergoes incomplete splicing

C. Secombes, C. Cunningham, J. Zou, 2001 .

Characterization of three novel beta-defensin antimicrobial peptides in rainbow trout (Oncorhynchus mykiss).

C. Secombes, S. Wadsworth, J. Zou, 2009, Molecular immunology.

A description of the origins, design and performance of the TRAITS–SGP Atlantic salmon Salmo salar L. cDNA microarray

R. Talbot, D. Houlihan, D. Tocher, 2008, Journal of fish biology.

The effects of diesel oil-based drilling mud extracts on immune responses of rainbow trout

C. Secombes, A. Tahir, Akbar Tahir, 1995, Archives of environmental contamination and toxicology.

Immunological approaches to control maturation in fish II. A review of the autoimmune approach

I. Priede, C. Secombes, L. Laird, 1987 .

Immunological approaches to control maturation in fish. 1. Cytotoxic reactions against germ cells using monoclonal antibodies

I. Priede, C. Secombes, J. G. M. Boogaart, 1986 .

The in vitro formation of teleost multinucleate giant cells

C. Secombes, 1985 .

The long‐term effects of auto‐immunologically induced granulomas on the testes of rainbowtrout, Salmo gairdneri Richardson

I. Priede, C. Secombes, L. Laird, 1985 .

Appearance of autoantigens during gonad maturation in the rainbow trout (Salmo gairdneri)

I. Priede, C. Secombes, L. Laird, 1985 .

EXPERIMENTALLY INDUCED IMMUNE REACTIONS TO GONAD IN RAINBOW TROUT (SALMO GAIRDNERI)

I. Priede, C. Secombes, L. Laird, 1985 .

Agglutination of spermatozoa by autoantibodies in the rainbow trout, Salmo gairdneri

I. Priede, C. Secombes, L. Laird, 1984 .

Separation of lymphocyte subpopulations in carp Cyprinus carpio L. by monoclonal antibodies: immunohistochemical studies.

E. Egberts, C. Secombes, J. V. van Groningen, 1983, Immunology.

The Control of Reproduction in Farmed Fish

C. Secombes, E. Riley, 1993 .

CDNA cloning and expression analysis of a cyclooxygenase-2 from sea bass (Dicentrarchus labrax L.) after vaccination

F. Buonocore, G. Scapigliati, C. Secombes, 2005 .

Four CISH paralogues are present in rainbow trout Oncorhynchus mykiss: differential expression and modulation during immune responses and development.

C. Secombes, S. Wadsworth, J. G. Vecino, 2014, Molecular immunology.

Genes for three different isoforms of transforming growth factor-beta are present in plaice (Pleuronectes platessa) DNA.

C. Secombes, C. Cunningham, K. Laing, 2000, Fish & shellfish immunology.

TGF-β3 exists in bony fish

C. Secombes, L. Pilström, C. Cunningham, 1999 .

Lymphokine-release from rainbow trout leucocytes stimulated with concanavalin A. Effects upon macrophage spreading and adherence.

C. Secombes, 1987, Developmental and comparative immunology.

The effect of primary and secondary immunization on the lymphoid tissues of the carp, Cyprinus carpio L.

M. Manning, C. Secombes, A. Ellis, 1982, The Journal of experimental zoology.

Potency testing of a live, genetically attenuated vaccine for salmonids.

T. Foster, C. Secombes, R. Fitzpatrick, 1998, Vaccine.

Isolation of the first piscine transforming growth factor beta gene: analysis reveals tissue specific expression and a potential regulatory sequence in rainbow trout (Oncorhynchus mykiss).

C. Secombes, L. Hardie, C. Cunningham, 1998, Cytokine.

Immunopurification of B Lymphocytes from Sea Bass Dicentrarchus labrax (L.).

P. Bossù, F. Buonocore, G. Scapigliati, 2003, Marine Biotechnology.

Effects of in vitro addition of infectious pancreatic necrosis virus (IPNV) on rainbow trout Oncorhynchus mykiss leucocyte responses.

A. Figueras, C. Secombes, B. Novoa, 1996, Veterinary immunology and immunopathology.

RAG-1 and IgM genes, markers for early development of the immune system in the gadoid haddock, Melanogrammus aeglefinus, L.

Y. Corripio-Miyar, C. Secombes, J. Treasurer, 2007, Fish & shellfish immunology.

An ELISPOT assay for the quantification of specific antibody-secreting cells to Aeromonas salmonicida in rainbow trout, Oncorhynchus mykiss (Walbaum)

C. Secombes, A. Ellis, G. A. Davidson, 1992 .

The development of an ELISPOT assay to quantify total and specific antibody-secreting cells in dab Limanda limanda (L.)

D. Houlihan, C. Secombes, T. C. Fletcher, 1991 .

Ontogeny of the immune system in fish--role of the thymus.

E. Egberts, C. Secombes, W. B. Van Muiswinkel, 1982, Advances in experimental medicine and biology.

Selenium Supplementation in Fish: A Combined Chemical and Biomolecular Study to Understand Sel-Plex Assimilation and Impact on Selenoproteome Expression in Rainbow Trout (Oncorhynchus mykiss)

Samuel A. M. Martin, J. Feldmann, C. Secombes, 2015, PloS one.

Immune Response and Protective Efficacy of Two New Adjuvants, MontanideTM ISA 763B VG and MontanideTM GEL02, Administered with a Streptococcus agalactiae Ghost Vaccine in Nile tilapia (Oreochromis niloticus).

C. Secombes, Tiehui Wang, S. Deville, 2021, Fish & shellfish immunology.

Impact of selenium supplementation on fish antiviral responses: a whole transcriptomic analysis in rainbow trout (Oncorhynchus mykiss) fed supranutritional levels of Sel-Plex®

J. Feldmann, J. Feldmann, C. Secombes, 2016, BMC Genomics.

Correction: Selenium Supplementation in Fish: A Combined Chemical and Biomolecular Study to Understand Sel-Plex Assimilation and Impact on Selenoproteome Expression in Rainbow Trout (Oncorhynchus mykiss)

Samuel A. M. Martin, J. Feldmann, C. Secombes, 2015, PloS one.

Inflammatory responses in primary muscle cell cultures in Atlantic salmon (Salmo salar)

C. Secombes, L. Tacchi, Nicholas J. Pooley, 2013, BMC Genomics.

Molecular cloning, gene organization and expression of rainbow trout (Oncorhynchus mykiss) inducible nitric oxide synthase (iNOS) gene

C. Secombes, P. Grabowski, Tiehui Wang, 2001 .

Seawater transfer alters the intestinal microbiota profiles of Atlantic salmon (Salmo salar L.)

C. Secombes, S. Martin, S. Martin, 2017, Scientific Reports.

A preliminary investigation into the phenomenon of oral tolerance in rainbow trout (Oncorhynchus mykiss, Walbaum, 1792)

C. Secombes, A. Ellis, G. A. Davidson, 1994 .

Interferon type I and type II responses in an Atlantic salmon (Salmo salar) SHK-1 cell line by the salmon TRAITS/SGP microarray.

R. Talbot, D. Houlihan, D. Tocher, 2007, Physiological genomics.

Comparative cardiac pathological changes of Atlantic salmon (Salmo salar L.) affected with heart and skeletal muscle inflammation (HSMI), cardiomyopathy syndrome (CMS) and pancreas disease (PD).

K. Skjødt, C. Secombes, J. Zou, 2013, Veterinary immunology and immunopathology.

Use of a lipid-emulsion carrier for immunisation of dab (Limanda limanda) by bath and oral routes : an assessment of systemic and mucosal antibody responses

C. Secombes, A. Ellis, G. A. Davidson, 2000 .

Route of immunization influences the generation of antibody secreting cells in the gut of rainbow trout (Oncorhynchus mykiss).

C. Secombes, A. Ellis, G. A. Davidson, 1993, Developmental and comparative immunology.

Viral and bacterial septicaemic infections modulate the expression of PACAP splicing variants and VIP/PACAP receptors in brown trout immune organs.

N. Taylor, C. Secombes, Y. Carpio, 2015, Fish & shellfish immunology.

Modes of Salmonid MHC Class I and II Evolution Differ from the Primate Paradigm1

P. Parham, C. Secombes, R. Hedrick, 2001, The Journal of Immunology.

Atlantic salmon adapted to seawater for 9 weeks develop a robust immune response to salmonid alphavirus upon bath challenge

C. Secombes, L. Moore, G. Taranger, 2018, Fish & shellfish immunology.

Immune gene profiles in Atlantic salmon (salmo salar L.) post‐smolts infected with SAV3 by bath‐challenge show a delayed response and lower levels of gene transcription compared to injected fish

C. Secombes, L. Moore, G. Taranger, 2017, Fish & shellfish immunology.

Individual monitoring of immune response in Atlantic salmon Salmo salar following experimental infection with piscine myocarditis virus (PMCV), agent of cardiomyopathy syndrome (CMS).

Ø. Evensen, C. Secombes, B. Collet, 2019, Developmental and comparative immunology.

Production and characterisation of an antiserum raised against recombinant rainbow trout (Oncorhynchus mykiss) MHC class II beta-chain (MhcOnmy-DAB)

C. Secombes, R. Stet, J. Knight, 1998 .

Migratory, respiratory burst and mitogenic responses of leucocytes isolated from the gills of rainbow trout (Oncorhynchus mykiss)

C. Secombes, A. Ellis, G. A. Davidson, 1999 .

The primary and secondary antibody responses to IROMP antigens in Atlantic salmon (Salmo salarL) immunised with A+and A−Aeromonas salmonicidabacterins

C. Secombes, A. Ellis, A. O'Dowd, 1999 .

Comparative study of CXC chemokines modulation in brown trout (Salmo trutta) following infection with a bacterial or viral pathogen.

N. Taylor, C. Secombes, S. Feist, 2016, Molecular immunology.

Salmonids Have an Extraordinary Complex Type I IFN System: Characterization of the IFN Locus in Rainbow Trout Oncorhynchus mykiss Reveals Two Novel IFN Subgroups

P. Boudinot, C. Secombes, C. Genet, 2014, The Journal of Immunology.

Immune gene expression profiling of proliferative kidney disease in rainbow trout Oncorhynchus mykiss reveals a dominance of anti-inflammatory, antibody and Th cell-like activities

C. Secombes, Tiehui Wang, J. Holland, 2013 .

Pituitary adenylate cyclase-activating peptide (PACAP) as potent modulator of innate and adaptive immune responses in fish

R. Gomariz, C. Secombes, C. Tafalla, 2013 .

Cellular responses of leucocytes isolated from the gut of rainbow trout, Oncorhynchus mykiss (Walbaum)

C. Secombes, A. Ellis, G. A. Davidson, 1991 .

Identification and characterisation of a novel immune-type receptor (NITR) gene cluster in the European sea bass, Dicentrarchus labrax, reveals recurrent gene expansion and diversification by positive selection

R. Reinhardt, D. Ritchie, L. Bargelloni, 2009, Immunogenetics.

The Cytokine Handbook 4th Edition

P. Kaiser, C. Secombes, 2003 .

Macrophage activation during experimental allergic orchitis in rainbow trout (Salmo gairdneri).

C. Secombes, 1986, Developmental and comparative immunology.

Fish macrophages express a cyclo-oxygenase-2 homologue after activation.

N. Neumann, M. Belosevic, C. Secombes, 1999, The Biochemical journal.

Isolation and Characterization of Salmonid CD4+ T Cells

Y. Corripio-Miyar, C. Secombes, A. Sandino, 2016, The Journal of Immunology.

The Peculiar Characteristics of Fish Type I Interferons

P. Boudinot, J. Levraud, C. Langevin, 2016, Viruses.

Five subfamilies of β-defensin genes are present in salmonids: Evolutionary insights and expression analysis in Atlantic salmon Salmo salar.

C. Secombes, Tiehui Wang, Qiaoqing Xu, 2019, Developmental and comparative immunology.

Insights into the Evolution of the Suppressors of Cytokine Signaling (SOCS) Gene Family in Vertebrates

C. Secombes, Tiehui Wang, E. Wangkahart, 2018, Molecular biology and evolution.

High-throughput proteomic profiling of the fish liver following bacterial infection

Samuel A. M. Martin, Dwight R. Causey, C. Secombes, 2018, BMC Genomics.

Insights into the fish thioredoxin system: expression profile of thioredoxin and thioredoxin reductase in rainbow trout (Oncorhynchus mykiss) during infection and in vitro stimulation.

C. Secombes, Tiehui Wang, J. Sweetman, 2014, Developmental and comparative immunology.

Characterisation of gamma-interferon responsive promoters in fish.

J. Lamas, C. Secombes, R. Castro, 2008, Molecular immunology.

Cloning of a novel interleukin (IL)-20-like gene in rainbow trout Oncorhynchus mykiss gives an insight into the evolution of the IL-10 family.

Samuel A. M. Martin, C. Secombes, S. Martin, 2010, Developmental and comparative immunology.

Evolution of interleukin-1beta.

B. Munday, C. Secombes, C. Cunningham, 2002, Cytokine & growth factor reviews.

Proteome analysis of the Atlantic salmon (Salmo salar) cell line SHK‐1 following recombinant IFN‐γ stimulation

P. Cash, D. Houlihan, C. Secombes, 2007, Proteomics.

Identification of an additional two-cysteine containing type I interferon in rainbow trout Oncorhynchus mykiss provides evidence of a major gene duplication event within this gene family in teleosts

C. Secombes, P. Nie, M. Chang, 2009, Immunogenetics.

Genomic organisation of rainbow trout, Oncorhynchus mykiss TGF-beta.

C. Secombes, G. Daniels, Garry D. Daniels, 1999, Developmental and comparative immunology.

Identification and characterization of TLR7, TLR8a2, TLR8b1 and TLR8b2 genes in Atlantic salmon (Salmo salar).

C. Secombes, J. Zou, J. Holland, 2013, Developmental and comparative immunology.

Modelling of fish interleukin-1 and its receptor.

P. Bossù, S. Costantini, F. Buonocore, 2004, Developmental and comparative immunology.

Characterisation, expression and promoter analysis of an interleukin 10 homologue in the puffer fish, Fugu rubripes

M. Clark, C. Secombes, J. Zou, 2003, Immunogenetics.

Fish Cytokine Genes

C. Secombes, J. Zou, B. Collet, 2003 .

Molecular cloning of the gene for interleukin-1β from Xenopus laevis and analysis of expression in vivo and in vitro

R. Minter, C. Secombes, C. Cunningham, 2000, Immunogenetics.

A Live ( D aroA ) Aeromonas salmonicida Vaccine for Furunculosis Preferentially Stimulates T-Cell Responses Relative to B-Cell Responses in Rainbow Trout ( Oncorhynchus mykiss )

T. Foster, C. Secombes, L. Vaughan, 1996 .

Identification of suppressor of cytokine signalling (SOCS) 6, 7, 9 and CISH in rainbow trout Oncorhynchus mykiss and analysis of their expression in relation to other known trout SOCS.

C. Secombes, P. Nie, Q. Gao, 2010, Fish & shellfish immunology.

The biological effects of rainbow trout (Oncorhynchus mykiss) recombinant interleukin-8.

C. Secombes, P. Nie, J. Zou, 2008, Developmental and comparative immunology.

Characterisation of the TNF superfamily members CD40L and BAFF in the small-spotted catshark (Scyliorhinus canicula).

Ronggai Li, C. Secombes, H. Dooley, 2015, Fish & shellfish immunology.

Evolution of IFN subgroups in bony fish - 2. analysis of subgroup appearance and expansion in teleost fish with a focus on salmonids.

Liangbiao Chen, M. Forlenza, C. Secombes, 2020, Fish & shellfish immunology.

Modulation of MHC class II expression in rainbow troutOncorhynchus mykissmacrophages by TNFα and LPS

C. Secombes, R. Stet, J. Knight, 1998 .

Characterization and gene expression analysis of the two main Th17 cytokines (IL-17A/F and IL-22) in turbot, Scophthalmus maximus.

A. Figueras, C. Secombes, B. Novoa, 2012, Developmental and comparative immunology.

Functional analysis of an orange-spotted grouper (Epinephelus coioides) interferon gene and characterisation of its expression in response to nodavirus infection.

C. Kuo, C. Secombes, Y. Kao, 2014, Developmental and comparative immunology.

C. Secombes, L. Tacchi, R. Bickerdike, 2012, Developmental and comparative immunology.

Binding of soluble immune complexes to fractionated Atlantic salmon (Salmo salar L.) leucocytes.

C. Secombes, A. Ellis, A. O'Dowd, 1999, Veterinary immunology and immunopathology.

Analysis of fish IL-1beta and derived peptide sequences indicates conserved structures with species-specific IL-1 receptor binding: implications for pharmacological design.

D. Ritchie, G. Kemp, C. Secombes, 2004, Current pharmaceutical design.

Identification of interleukin-22 in gadoids and examination of its expression level in vaccinated fish.

Y. Corripio-Miyar, C. Secombes, J. Zou, 2009, Molecular immunology.

Genomic organisation analysis of novel immunoglobulin-like transcripts in Atlantic salmon (Salmo salar) reveals a tightly clustered and multigene family

C. Secombes, W. Davidson, R. Stet, 2010, BMC Genomics.

Cloning, promoter analysis and expression in response to bacterial exposure of sea bass (Dicentrarchus labrax L.) interleukin-12 p40 and p35 subunits.

C. Secombes, D. Nascimento, A. do Vale, 2007, Molecular immunology.

Analysis of interferon gamma protein expression in zebrafish (Danio rerio).

C. Secombes, Tzong-Yueh Chen, J. Zou, 2016, Fish & shellfish immunology.

Cloning and characterisation of rainbow trout Interleukin (IL)-17A/F2 and IL-17RA:

C. Secombes, J. Zou, Tiehui Wang, 2012 .

Cloning and analysis of expression of a gilthead sea bream (Sparus aurata) Mx cDNA.

A. Figueras, C. Secombes, B. Novoa, 2004, Fish & shellfish immunology.

The rainbow trout (Oncorhynchus mykiss) Mx1 promoter

C. Secombes, B. Collet, 2001 .

The rainbow trout (Oncorhynchus mykiss) Mx1 promoter. Structural and functional characterization.

C. Secombes, B. Collet, 2001, European journal of biochemistry.

Effect of intraperitoneally administered IL-1beta-derived peptides on resistance to viral haemorrhagic septicaemia in rainbow trout Oncorhynchus mykiss.

C. Secombes, A. Ellis, S. Peddie, 2003, Diseases of aquatic organisms.

Intracellular Interferons in Fish: A Unique Means to Combat Viral Infection

C. Secombes, P. Nie, M. Chang, 2013, PLoS pathogens.

Bioactivity studies of rainbow trout (Oncorhynchus mykiss) interleukin-6: effects on macrophage growth and antimicrobial peptide gene expression.

C. Secombes, Tiehui Wang, P. Díaz‐Rosales, 2011, Molecular immunology.

First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio)

C. Wyse, C. Secombes, S. Mitra, 2015, PloS one.

T-cell antigen receptor genes in turbot (Scophthalmus maximus L.).

C. Secombes, T. Birkbeck, M. Tatner, 2005, Fish & shellfish immunology.

Functional conservation of suppressors of cytokine signaling proteins between teleosts and mammals: Atlantic salmon SOCS1 binds to JAK/STAT family members and suppresses type I and II IFN signaling.

A. Skjesol, C. Secombes, D. Iliev, 2014, Developmental and comparative immunology.

Post-transcriptional regulation of cytokine genes in fish: A role for conserved AU-rich elements located in the 3'-untranslated region of their mRNAs.

J. Meseguer, M. Cayuela, C. Secombes, 2007, Molecular immunology.

Construction and analysis of a secreting expression vector for fish cells.

C. Secombes, B. Collet, 2005, Vaccine.

Rainbow trout suppressor of cytokine signalling (SOCS)-1, 2 and 3: molecular identification, expression and modulation.

C. Secombes, Tiehui Wang, 2008, Molecular immunology.

In vitro transformation of Diplostomum spathaceum (Digenea) cercariae and short term maintenance of post-penetration larvae in vitro

S. Whyte, C. Secombes, L. Chappell, 1988, Journal of Helminthology.

The rainbow trout Oncorhynchus mykiss interleukin-1 beta gene has a differ organization to mammals and undergoes incomplete splicing.

C. Secombes, C. Cunningham, J. Zou, 1999, European journal of biochemistry.

Muscle-Specific RING Finger (MuRF) cDNAs in Atlantic Salmon (Salmo salar) and Their Role as Regulators of Muscle Protein Degradation

C. Secombes, L. Tacchi, R. Bickerdike, 2012, Marine Biotechnology.

Interleukin-10 expression by real-time PCR and homology modelling analysis in the European sea bass (Dicentrarchus Labrax L.)

S. Costantini, F. Buonocore, G. Scapigliati, 2007 .

Molecular cloning and expression analysis of sea bass (Dicentrarchus labrax L.) tumor necrosis factor-α (TNF-α)

C. Secombes, D. Nascimento, Manuel T. Silva, 2007 .

Cloning of iNOS in the small spotted catshark (Scyliorhinus canicula).

A. Goostrey, C. Secombes, Jennifer I Reddick, 2006, Developmental and comparative immunology.

The RxLR Motif of the Host Targeting Effector AVR3a of Phytophthora infestans Is Cleaved before Secretion[OPEN]

U. Linne, P. van West, Stephan Wawra, 2017, Plant Cell.

Montanide™ ISA 763A VG and ISA 761 VG induce different immune pathway responses in rainbow trout (Oncorhynchus mykiss) when used as adjuvant for an Aeromonas salmonicida bacterin.

J. Ben Arous, C. Secombes, Tiehui Wang, 2021, Fish & shellfish immunology.

Cloning and sequencing of caspase 6 in rainbow trout, Oncorhynchus mykiss, and analysis of its expression under conditions known to induce apoptosis.

C. Secombes, C. Cunningham, K. Laing, 2001, Developmental and comparative immunology.

Establishment of an IFN-gamma specific reporter cell line in fish.

C. Secombes, J. Zou, R. Castro, 2010, Fish & shellfish immunology.

Inhibition of rainbow trout phagocyte responsiveness tohuman tumor necrosis factor a(hTNFa) with monoclonal antibodies to the hTNFa 55 kDa receptor

S. Jang, C. Secombes, L. Hardie, 1995 .

Time-course study of the protection induced by an interferon-inducible DNA vaccine against viral haemorrhagic septicaemia in rainbow trout.

C. Secombes, E. Lorenzen, B. Collet, 2019, Fish & shellfish immunology.

The longevity of the antimicrobial response in rainbow trout (Oncorhynchus mykiss) fed a peptidoglycan (PG) supplemented diet.

C. Secombes, S. Wadsworth, S. Bird, 2015, Fish & shellfish immunology.

Discovery and characterization of two types of liver-expressed antimicrobial peptide 2 (LEAP-2) genes in rainbow trout.

C. Secombes, J. Zou, Chin-I Chang, 2004, Veterinary immunology and immunopathology.

Two peptides derived from trout IL-1beta have different stimulatory effects on immune gene expression after intraperitoneal administration.

C. Secombes, Suhee Hong, 2009, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

The Immunology of Teleosts

C. Secombes, A. Ellis, 2012 .

Immunology of Fish

C. Secombes, T. C. Fletcher, 2010 .

Seawater transfer alters the intestinal microbiota profiles of Atlantic salmon (Salmo salar L.)

C. Secombes, S. Martin, C. Dehler, 2017, Scientific Reports.

Overview of the Fish Adaptive Immune System

C. Secombes, R. Belmonte, 2016 .

Cloning and expression analysis of two ROR-γ homologues (ROR-γa1 and ROR-γa2) in rainbow trout Oncorhynchus mykiss.

C. Secombes, Tiehui Wang, M. Monte, 2012, Fish & shellfish immunology.

Cell entry of a host-targeting protein of oomycetes requires gp96

Thomas Schrader, Peter Bayer, Andreas Wuensch, 2018, Nature Communications.

Rainbow trout (Oncorhynchus mykiss) possess multiple novel immunoglobulin-like transcripts containing either an ITAM or ITIMs.

C. Secombes, R. Stet, Tiehui Wang, 2009, Developmental and comparative immunology.

Three monoclonal antibodies to the VHS virus glycoprotein: comparison of reactivity in relation to differences in immunoglobulin variable domain gene sequences.

C. Secombes, C. Cunningham, N. Lorenzen, 2000, Fish & shellfish immunology.

Molecular cloning, gene organization and expression of rainbow trout (Oncorhynchus mykiss) inducible nitric oxide synthase (iNOS) gene.

C. Secombes, P. Grabowski, Tiehui Wang, 2001, The Biochemical journal.

Characterisation and expression analysis of B-cell activating factor (BAFF) in spiny dogfish (Squalus acanthias): cartilaginous fish BAFF has a unique extra exon that may impact receptor binding.

Ronggai Li, C. Secombes, H. Dooley, 2012, Developmental and comparative immunology.

Functional Characterization of a Nonmammalian IL-21: Rainbow Trout Oncorhynchus mykiss IL-21 Upregulates the Expression of the Th Cell Signature Cytokines IFN-γ, IL-10, and IL-22

Samuel A. M. Martin, C. Secombes, M. Snow, 2011, The Journal of Immunology.

Cytokines IFN- Expression of the Th Cell Signature IL-21 Upregulates the Oncorhynchus mykiss Nonmammalian IL-21: Rainbow Trout Functional Characterization of a

C. Secombes, M. Snow, B. Collet, 2017 .

Effects of temperature on amoebic gill disease

C. Collins, C. Secombes, T. Pottinger, 2019 .

Atlantic salmon physiological and immune response to amoebic gill disease and insight into the biology of the amoeba

C. Collins, C. Secombes, O. Benedicenti, 2016 .

Molecular cloning and expression analysis of sea bass (Dicentrarchus labrax L.) tumor necrosis factor-alpha (TNF-alpha).

C. Secombes, D. Nascimento, A. do Vale, 2007, Fish & shellfish immunology.

Different origins of paralogues of salmonid TNR1 and TNFR2: Characterisation and expression analysis of four TNF receptor genes in rainbow trout Oncorhynchus mykiss.

C. Secombes, Tiehui Wang, Suhee Hong, 2019, Developmental and comparative immunology.

Two types of TNF&agr; in meagre (Argyrosomus regius): Discovery, distribution and expression modulation

K. Andree, C. Secombes, J. Zou, 2017, Molecular immunology.

Isolation of rainbow trout (Oncorhynchus mykiss) intestinal intraepithelial lymphocytes (IEL) and measurement of their cytotoxic activity

C. Secombes, D. N. Mcmillan, 1997 .

Immunolocalization of immune cells and cell cycle proteins in the bulbus arteriosus of Atlantic salmon (Salmo salar L.).

C. Secombes, J. Zou, E. Koppang, 2016, Fish & shellfish immunology.

A CXC chemokine sequence isolated from the rainbow trout Oncorhynchus mykiss resembles the closely related interferon-gamma-inducible chemokines CXCL9, CXCL10 and CXCL11.

C. Secombes, N. Bols, K. Laing, 2003, European cytokine network.

Evolution of the CD4 Family: Teleost Fish Possess Two Divergent Forms of CD4 in Addition to Lymphocyte Activation Gene-31

C. Secombes, J. Hansen, J. Zou, 2006, The Journal of Immunology.

Modulation of dab (Limanda limanda, L.) macrophage respiratory burst activity

C. Secombes, A. Tahir, 1996 .

Elevation of rainbow trout Oncorhynchus mykiss macrophage respiratory burst activity with macrophage‐derived supernatants

S. Jang, C. Secombes, L. Hardie, 1995, Journal of leukocyte biology.

The gamma-chain cytokine/receptor system in fish: more ligands and receptors.

C. Secombes, Wen-shu Huang, Tiehui Wang, 2011, Fish & shellfish immunology.

Adaptive immunity in teleosts: cellular immunity.

C. Secombes, J. Zou, S. Bird, 2005, Developments in Biologicals.

Novel insights into the cytokine network of rainbow trout Oncorhynchus mykiss using cell lines and primary leukocyte populations.

C. Secombes, B. Dixon, C. Tafalla, 2023, Fish and Shellfish Immunology.

Evolution of IFN subgroups in bony fish - 1:Group I-III IFN exist in early ray-finned fish, with group II IFN subgroups present in the Holostean spotted gar, Lepisosteus oculatus.

C. Secombes, N. Bols, J. Zou, 2019, Fish & shellfish immunology.

Sequencing of a second interleukin-10 gene in rainbow trout Oncorhynchus mykiss and comparative investigation of the expression and modulation of the paralogues in vitro and in vivo.

C. Secombes, Tiehui Wang, M. M. Costa, 2011, Fish & shellfish immunology.

Identification and expression analysis of two fish-specific IL-6 cytokine family members, the ciliary neurotrophic factor (CNTF)-like and M17 genes, in rainbow trout Oncorhynchus mykiss.

C. Secombes, Tiehui Wang, 2009, Molecular immunology.

Type I-interferon signalling in fish.

C. Secombes, B. Collet, 2002, Fish & shellfish immunology.

Cell entry of a host-targeting protein of oomycetes requires gp96

T. Schrader, T. Rasmussen, P. van West, 2018, Nature Communications.

Development of a 3D spheroid cell culture system from fish cell lines for in vitro infection studies: Evaluation with Saprolegnia parasitica.

P. van West, C. Secombes, M. Faber, 2021, Journal of fish diseases.

The immunostimulatory effects of Chevimmun on the rainbow trout (Oncorhnychus mykiss)

C. Secombes, S. Peddie, 2003 .

TheputativeRxLRe ¡ ector proteinSpHtp 1 fromthe ¢ sh pathogenic oomyceteSaprolegnia parasitica is translocated into ¢ sh cells

P. West, Victoria L. Anderson, Stephan Wawra, 2010 .

Cloning of two chemokine receptor homologs (CXC‐R4 andCC‐R7)in rainbow trout Oncorhynchus mykiss

C. Secombes, C. Cunningham, J. Zou, 1999, Journal of leukocyte biology.

Differential responses of the gut transcriptome to plant protein diets in farmed Atlantic salmon

J. Speakman, D. Tocher, C. Secombes, 2016, BMC Genomics.

Addition to Lymphocyte Activation Gene-3 Possess Two Divergent Forms of CD 4 in Evolution of the CD 4 Family : Teleost

C. Secombes, J. Hansen, J. Zou, 2006 .

Article (refereed) - postprint

C. Collins, C. Secombes, T. Pottinger, 2019 .

Antiviral sensing in teleost fish.

C. Secombes, J. Zou, S. Bird, 2010, Current pharmaceutical design.

CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell–like Populations and Diverse Mononuclear Phagocytes

A. Cvejic, C. Secombes, A. Hurlstone, 2016, The Journal of Immunology.

TRAITS / SGP microarray ) SHK-1 cell line by the salmon Salmo salar salmon ( Interferon type I and type II responses in an Atlantic

R. Talbot, D. Houlihan, D. Tocher, 2007 .

Cloning and expression of a putative common cytokine receptor gamma chain (gammaC) gene in rainbow trout (Oncorhynchus mykiss).

C. Secombes, T. Wang, 2001, Fish & shellfish immunology.

CpG oligodeoxynucleotides up-regulate antibacterial systems and induce protection against bacterial challenge in rainbow trout (Oncorhynchus mykiss).

C. Secombes, A. Carrington, 2007, Fish & shellfish immunology.

High-throughput proteomic profiling of the fish liver following bacterial infection

Dwight R. Causey, C. Secombes, D. Macqueen, 2018, BMC Genomics.

Characterisation of ZBTB46 and DC‐SCRIPT/ZNF366 in rainbow trout, transcription factors potentially involved in dendritic cell maturation and activation in fish

C. Collins, C. Secombes, J. Zou, 2018, Developmental and comparative immunology.

Immunopurification of T-cells from sea bass Dicentrarchus labrax (L.).

F. Buonocore, G. Scapigliati, C. Secombes, 2000, Fish & shellfish immunology.

The effect of stress on the immune response of Atlantic salmon (Salmo salar L.) fed diets containing different amounts of vitamin C

Christopher J. Secombes, Ann White, Dominic F. Houlihan, 1993 .

Effect of serum factors on the survival of Renibacterium salmoninarum within rainbow trout macrophages

C. Secombes, A. Ellis, J. Barja, 1995 .

Immunisation of rainbow trout Oncorhynchus mykiss with a multiple antigen peptide system (MAPS).

E. M. Riley, C. Secombes, S. Young, 1996, Veterinary immunology and immunopathology.

Characterization and expression analysis of an interleukin‐7 homologue in the Japanese pufferfish, Takifugu rubripes

C. Secombes, R. Savan, M. Sakai, 2008, The FEBS journal.

Cross Talk Between Growth and Immunity: Coupling of the IGF Axis to Conserved Cytokine Pathways in Rainbow Trout.

P. Boudinot, C. Secombes, R. Castro, 2016, Endocrinology.

Identification of the salmonid IL-17A/F1a/b, IL-17A/F2b, IL-17A/F3 and IL-17N genes and analysis of their expression following in vitro stimulation and infection

C. Secombes, Yousheng Jiang, Tiehui Wang, 2015, Immunogenetics.

Distinctive Expansion of Potential Virulence Genes in the Genome of the Oomycete Fish Pathogen Saprolegnia parasitica

B. Snel, C. Nusbaum, C. Russ, 2013, PLoS genetics.

Sequencing of a second interleukin-10 gene in rainbow trout Oncorhynchus mykiss and comparative investigation of the expression and modulation of the paralogues in vitro and in vivo.

C. Secombes, Tiehui Wang, M. M. Costa, 2011, Fish & shellfish immunology.

Time-course study of the protection induced by an interferon-inducible DNA vaccine against viral haemorrhagic septicaemia in rainbow trout.

C. Secombes, E. Lorenzen, B. Collet, 2019, Fish & shellfish immunology.

Ontogeny and modulation after PAMPs stimulation of β-defensin, hepcidin, and piscidin antimicrobial peptides in meagre (Argyrosomus regius).

K. Andree, C. Secombes, N. Duncan, 2017, Fish and Shellfish Immunology.

Modes of Salmonid MHC Class I and II Evolution Differ from the Primate Paradigm1

P. Parham, C. Secombes, L. Guethlein, 2001, The Journal of Immunology.

Characterisation and analysis of IFN-gamma producing cells in rainbow trout Oncorhynchus mykiss.

C. Secombes, C. Tafalla, Tiehui Wang, 2021, Fish and Shellfish Immunology.

Cloning and expression analysis of two pro-inflammatory cytokines, IL-1 beta and IL-8, in haddock (Melanogrammus aeglefinus).

Y. Corripio-Miyar, C. Secombes, S. Bird, 2007, Molecular immunology.

Molecular characterization of IRF3 and IRF7 in rainbow trout, Oncorhynchus mykiss: functional analysis and transcriptional modulation.

C. Secombes, B. Williamson, J. Zou, 2008, Molecular immunology.

Rainbow trout interleukin-2: cloning, expression and bioactivity analysis.

C. Secombes, J. Zou, Tiehui Wang, 2009, Fish & shellfish immunology.

Identification and expression modulation of a C-type lectin domain family 4 homologue that is highly expressed in monocytes/macrophages in rainbow trout (Oncorhynchus mykiss).

Y. Corripio-Miyar, C. Secombes, J. Zou, 2016, Developmental and comparative immunology.

GUT HEALTH AND INTEGRITY IN ATLANTIC SALMON FED PLANT PROTEIN DIETS

C. Secombes, E. Król, A. Douglas, 2016 .

Cortisol modulates the induction of inflammatory gene expression in a rainbow trout macrophage cell line.

C. Secombes, J. Zou, R. Castro, 2011, Fish & shellfish immunology.