T. Kan

S. Onoue, S. Yamada, Tatsuya Nakamura, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Two New Cu(II) Coordination Polymers with 2D and 1D Frameworks that Show Reversible Structural Transformations Depending on the Present Solvents

T. Kan, M. Kondo, Katsunori Yamanishi, 2021 .

Concise synthesis of polymethoxyflavone sudachitin and its derivatives, and biological evaluations

T. Asakawa, T. Kan, T. Ishikawa, 2018 .

Development of photoaffinity probes for gamma-secretase equipped with a nitrobenzenesulfonamide-type cleavable linker.

T. Iwatsubo, Yoichi Kita, T. Kan, 2009, Bioorganic & medicinal chemistry letters.

Chemoselective hydrogenation reaction of unsaturated bonds in the presence of an o-nitrobenzenesulfonyl group.

Y. Hamashima, H. Sajiki, T. Asakawa, 2013, Organic letters.

Structure-activity relationship study on alpha1 adrenergic receptor antagonists from beer.

M. Nitta, M. Ishiguro, T. Kan, 2009, Bioorganic & medicinal chemistry letters.

Discovery of Plant Growth Stimulants by C-H Arylation of 2-Azahypoxanthine.

T. Kan, K. Itami, H. Kawagishi, 2018, Organic letters.

Total synthesis of (−)-ephedradine A: an efficient construction of optically active dihydrobenzofuran-ring via C–H insertion reaction

T. Kan, T. Fukuyama, Hideki Kobayashi, 2004 .

Highly efficient synthesis of medium-sized lactams via intramolecular Staudinger–aza-Wittig reaction of ω-azido pentafluorophenyl ester: synthesis and biological evaluation of LY411575 analogues

T. Iwatsubo, T. Kan, T. Tomita, 2004 .

Stereocontrolled total synthesis of (-)-ephedradine A (orantine).

T. Kan, T. Fukuyama, Wataru Kurosawa, 2003, Journal of the American Chemical Society.

Synthesis of the optically active key intermediate of FR901483

T. Kan, T. Fukuyama, Shigeru Ieda, 2010 .

Stereocontrolled total synthesis of hedyotol A.

Y. Hamashima, T. Asakawa, T. Kan, 2014, Organic letters.

Total Synthesis of (-)-Grayanotoxin III

F. Matsuda, T. Kan, M. Oikawa, 1994 .

Total Synthesis of TAN1251C via Diastereoselective Construction of the Azaspiro Skeleton.

Y. Ishikawa, Y. Hamashima, T. Asakawa, 2017, Organic letters.

Total synthesis of ecteinascidin 743.

T. Kan, T. Fukuyama, A. Yanagisawa, 2002, Journal of the American Chemical Society.

Total synthesis of (+/-)-morphine.

T. Kan, T. Fukuyama, S. Yokoshima, 2006, Organic letters.

Total synthesis of (-)-lemonomycin.

Y. Hamashima, T. Asakawa, T. Kan, 2012, Chemistry.

Synthetic studies on (+)-naphthyridinomycin: stereoselective synthesis of the tetracyclic core framework.

T. Kan, K. Mori, T. Fukuyama, 2004, Organic Letters.

Synthesis of Chemical-Biology Tools Enabling in vivo Imaging and Analysis of Epigallocatechin Gallate

K. Itoh, N. Oku, K. Shimizu, 2016 .

Highly Versatile Synthesis of Nitrogen-Containing Compounds by Means of Nitrobenzenesulfonamides

T. Kan, T. Fukuyama, 2001 .

Furan fatty acid as an anti-inflammatory component from the green-lipped mussel Perna canaliculus

I. Abe, T. Asakawa, T. Kan, 2011, Proceedings of the National Academy of Sciences.

Divergent synthesis of multifunctional molecular probes to elucidate the enzyme specificity of dipeptidic gamma-secretase inhibitors.

T. Iwatsubo, T. Kan, T. Tomita, 2007, ACS chemical biology.

Total synthesis of (-)-serotobenine.

T. Kan, T. Wakimoto, T. Fukuyama, 2008, Journal of the American Chemical Society.

Modified Julia-KocienskiReaction Promoted by Means of m-NPT (Nitro-phenyltetrazole)Sulfone

T. Kan, T. Wakimoto, Yuji Yamada, 2010 .

Asymmetric syntheses of 5‐ and 6‐membered carbocyclic serine analogs via an intramolecular Strecker synthesis

T. Kan, T. Nakajima, Y. Ohfune, 1997 .

Efficient synthesis of phenanthridinone derivatives via a palladium-catalyzed coupling process.

S. Fujii, T. Kan, Kiyoshi Tanaka, 2007, Organic letters.

2,4-Dinitrobenzenesulfonamides: A simple and practical method for the preparation of a variety of secondary amines and diamines

T. Kan, M. Cheung, T. Fukuyama, 1997 .

Synthetic studies on (-)-lemonomycin: stereocontrolled construction of the 3,8-diazabicyclo[3.2.1] skeleton.

T. Kan, K. Mori, T. Fukuyama, 2005, Chemical communications.

Synthetic Studies on (+)-Naphthyridinomycin (II): Stereoselective Synthesis of the Tetracyclic Core Framework (I).

T. Kan, K. Mori, T. Fukuyama, 2004 .

Synthesis of Optically Active α-Arylglycines: Stereoselective Mannich-Type Reaction with a New Chiral Template

T. Kan, T. Fukuyama, A. Endo, 2001 .

Synthetic studies on (+)-manzamine A: stereoselective synthesis of the tetracyclic core framework.

Yoichi Kita, T. Kan, T. Fukuyama, 2008, Organic letters.

Enantioselective total synthesis of aperidine.

T. Asakawa, T. Kan, T. Wakimoto, 2011, Organic letters.

Stereocontrolled total synthesis of (+)-UCS1025A.

Y. Hamashima, T. Asakawa, T. Kan, 2012, Angewandte Chemie.

A Novel Synthesis of Bicyclo[3.3.0]octane Ring System via a Desymmetric C-H Insertion Reaction

Yuichiro Kawamoto, T. Kan, Tohru Inoue, 2006 .

Enantioselective synthesis of SB-203207.

Yuichiro Kawamoto, T. Asakawa, T. Kan, 2014, Organic letters.

Total Synthesis of Sophoraflavanone H and Confirmation of Its Absolute Configuration.

Y. Ishikawa, T. Asakawa, T. Kan, 2020, Organic letters.

Stereoselective construction of 2-vinyl 3-hydroxybenzopyran rings: total syntheses of teadenols A and B.

Y. Hamashima, T. Asakawa, T. Kan, 2016, Organic & biomolecular chemistry.

Synthetic Studies on Pactamycin: A Synthesis of Johnson's Intermediate.

T. Kan, Yusuke Miura, Junichiro Kanazawa, 2020, Organic letters.

Total synthesis of natural products using a desymmetrization strategy

T. Asakawa, T. Kan, M. Inai, 2018 .

Catalytic desymmetrization of cyclohexadienes by asymmetric bromolactonization.

Y. Hamashima, T. Asakawa, T. Kan, 2012, Organic letters.

Preparation of Secondary Amines From Primary Amines Via 2‐Nitrobenzenesulfonamides: N‐(4‐Methoxybenzyl)‐3‐Phenylpropylamine

T. Kan, T. Fukuyama, Wataru Kurosawa, 2003 .

Novel gamma-secretase inhibitors discovered by library screening of in-house synthetic natural product intermediates.

Yasuko Takahashi, Takeshi Iwatsubo, Makoto Sasaki, 2006, Bioorganic & medicinal chemistry letters.

Synthesis of A-B-C-ring segment of thyrsiferol construction of a strained tetrahydropyran ring existent as a boat form

T. Kan, Takeshi Matsumoto, H. Shirahama, 1987 .

Hydroxy-Directed, SmI2-Induced Conversion of Carbohydrates into Carbocycles

F. Matsuda, T. Kan, H. Shirahama, 2000 .

Effective deprotection of 2-(trimethylsilylethoxy)methylated alcohols (SEM ethers). Synthesis of thyrsiferyl-23 acetate

T. Kan, H. Shirahama, M. Hashimoto, 1988 .

Efficient macrocyclization by means of 2-nitrobenzenesulfonamide and total synthesis of lipogrammistin-A

T. Kan, T. Fukuyama, Hideki Kobayashi, 2002 .

Synthesis of axially chiral amino acid and amino alcohols via additive-ligand-free Pd-catalyzed domino coupling reaction and subsequent transformations of the product amidoaza[5]helicene.

T. Kawabata, T. Kan, Y. Kitamura, 2010, The Journal of organic chemistry.

Synthetic Study on Pactamycin: Stereoselective Synthesis of the Cyclopentane Core Framework.

Y. Hamashima, T. Asakawa, T. Kan, 2017, Organic letters.

Expression and functional analysis of the nobiletin biosynthesis-related gene CitOMT in citrus fruit

T. Kan, G. Ma, Lancui Zhang, 2020, Scientific Reports.

Diastereo- and regiodivergent total synthesis of princepin and isoprincepin in both (7"R, 8''R) and (7"S, 8''S) isomers.

T. Asakawa, T. Kan, M. Inai, 2019, The Journal of organic chemistry.

Synthesis of biotinylated photoaffinity probes based on arylsulfonamide γ-secretase inhibitors

Yasuko Takahashi, Takeshi Iwatsubo, Tohru Fukuyama, 2006 .

Synthesis of diazirine possessing an acetophenone derivative as a valuable intermediate for a flavonoid photoaffinity probe

T. Kan, M. Ueda, Kiyoshi Tanaka, 2008 .

Structural characteristics of green tea catechins for formation of protein carbonyl in human serum albumin.

Yoshinori Uekusa, T. Kan, T. Wakimoto, 2010, Bioorganic & medicinal chemistry.

Synthesis of Diazirine Possessing an Acetophenone Derivative as a Valuable Intermediate for a Flavonoid Photoaffinity Probe.

T. Kan, M. Ueda, Kiyoshi Tanaka, 2009 .

3,3',4',5'-Tetrahydroxyflavone induces formation of large aggregates of amyloid β protein.

K. Abe, T. Asakawa, T. Kan, 2014, Biological & pharmaceutical bulletin.

Synthesis of Theaflavins via Biomimetic Oxidative Coupling Reactions

Y. Hamashima, T. Asakawa, T. Kan, 2013, Synlett.

Proof of the existence of an unstable amino acid: pleurocybellaziridine in Pleurocybella porrigens.

T. Asakawa, T. Kan, T. Wakimoto, 2011, Angewandte Chemie.

Total synthesis of polyamine toxin HO-416b and Agel-489 using a 2-nitrobenzenesulfonamide strategy.

T. Kan, T. Fukuyama, Y. Hidai, 2000, Chemical & pharmaceutical bulletin.

Total Synthesis of Lipogrammistin-A: Efficient Macrocyclization with 2-Nitrobenzenesulfonamide

T. Kan, T. Fukuyama, A. Fujiwara, 2000 .

Total syntheses of (+)-thyrsiferol, (+)-thyrsiferyl 23-acetate, and (+)-venustatriol

T. Kan, Takeshi Matsumoto, H. Shirahama, 1990 .

Total synthesis of (+)-thyrsiferol and (+)-venustatriol

T. Kan, Takeshi Matsumoto, H. Shirahama, 1988 .

Synthetic studies on altemicidin: stereocontrolled construction of the core framework.

Yuichiro Kawamoto, T. Asakawa, T. Kan, 2008, Organic letters.

Stereocontrolled total synthesis of (−)-myriocin

T. Kan, T. Wakimoto, M. Inai, 2008 .

Rapid LC-MS Determination of Acromelic Acids A and B, Toxic Constituents of the Mushroom Paralepistopsis acromelalga.

T. Kan, H. Ouchi, N. Yoshioka, 2017, Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan.

Effect of 2-Azahypoxanthine (AHX) Produced by the Fairy-Ring-Forming Fungus on the Growth and the Grain Yield of Rice

R. Motohashi, A. Morita, Takashi Ikka, 2015 .

2-Azahypoxanthine and imidazole-4-carboxamide produced by the fairy-ring-forming fungus increase wheat yield

A. Morita, T. Asakawa, T. Kan, 2014 .

Stereocontrolled Total Synthesis of Sphingofungin E

Y. Hamashima, T. Asakawa, T. Kan, 2013 .

Stereocontrolled total synthesis of potent immunosuppressant FR901483.

T. Kan, T. Fukuyama, T. Fujimoto, 2004, Organic letters.

Efficient Synthesis of Medium-Sized Cyclic Amines by Means of 2-Nitrobenzenesulfonamide

T. Kan, T. Fukuyama, Hideki Kobayashi, 2002 .

Practical Total Syntheses of Acromelic Acids A and B.

Y. Hamashima, T. Asakawa, T. Kan, 2014, Chemical & pharmaceutical bulletin.

Biosynthesis of the Fairy Chemicals, 2-Azahypoxanthine and Imidazole-4-carboxamide, in the Fairy Ring-Forming Fungus Lepista sordida.

Hirofumi Hirai, T. Asakawa, T. Kan, 2020, Journal of natural products.

Ribosides and Ribotide of a Fairy Chemical, Imidazole-4-carboxamide, as Its Metabolites in Rice.

Hirofumi Hirai, T. Asakawa, T. Kan, 2019, Organic letters.

A Fairy Chemical, Imidazole-4-carboxamide, is Produced on a Novel Purine Metabolic Pathway in Rice

R. Motohashi, Hirofumi Hirai, T. Asakawa, 2019, Scientific Reports.

Stereocontrolled Total Synthesis of Sphingofungin E.

Y. Hamashima, T. Asakawa, T. Kan, 2014 .

Stereoselective Cyclization Mediated by Samarium(II) Iodide Using Allyl Sulfides and Sulfones as Ketyl Radical Acceptors

F. Matsuda, T. Kan, H. Shirahama, 1994 .

Transdermal delivery of nobiletin using ionic liquids

S. Mitragotri, T. Kan, T. Hattori, 2019, Scientific Reports.

A Negative Feedback Loop Controlling bHLH Complexes Is Involved in Vascular Cell Division and Differentiation in the Root Apical Meristem

H. Fukuda, T. Asakawa, T. Kan, 2015, Current Biology.

An efficient screening method for purifying and crystallizing membrane proteins using modified clear-native PAGE.

So Iwata, Takeshi Murata, Yuuki Takamuku, 2018, Analytical biochemistry.

Practical synthesis of natural plant-growth regulator 2-azahypoxanthine, its derivatives, and biotin-labeled probes.

Y. Hamashima, T. Asakawa, T. Kan, 2014, Organic & biomolecular chemistry.

Concise synthesis of chafurosides A and B.

T. Kan, T. Wakimoto, H. Nukaya, 2009, Organic letters.

Efficient synthesis of phenanthridinone derivatives via a palladium-catalyzed coupling process.

S. Fujii, T. Kan, Kiyoshi Tanaka, 2007, Organic letters.

Highly Versatile Synthesis of Polyamines by Ns-strategy on a Novel Trityl Chloride Resin

T. Kan, T. Fukuyama, Hideki Kobayashi, 2002 .

Sulindac Sulfide Is a Noncompetitive γ-Secretase Inhibitor That Preferentially Reduces Aβ42 Generation*

T. Iwatsubo, T. Kan, T. Tomita, 2003, The Journal of Biological Chemistry.

Effect of (−)-Epigallocatechin Gallate on Activation of JAK/STAT Signaling Pathway by Staphylococcal Enterotoxin A

T. Kan, S. Masuda, Y. Shimamura, 2021, Toxins.

Structural specificity of electric potentials in the coulometric-array analysis of catechins and theaflavins

T. Kan, T. Ishii, T. Nakayama, 2014, Journal of clinical biochemistry and nutrition.

Stereocontrolled Construction of B-Ring of Grayanotoxins via Samarium(II) Iodide Promoted Pinacol Coupling Cyclization

F. Matsuda, T. Kan, H. Shirahama, 1991 .

Total synthesis of polyamine toxin HO-416b utilizing the 2-nitrobenzenesulfonamide protecting group

T. Kan, T. Fukuyama, Y. Hidai, 1999 .

Practical Synthesis of Spermine, Thermospermine and Norspermine.

H. Fukuda, T. Asakawa, T. Kan, 2016, Chemical & pharmaceutical bulletin.

2‐Nitrobenzenesulfonyl Chloride

T. Kan, T. Fukuyama, 2004 .

Total Synthesis of Polyamine Toxin HO‐416b Utilizing the 2‐Nitrobenzenesulfonamide Protecting Group.

T. Kan, T. Fukuyama, Y. Hidai, 1999 .

Nobiletin: a citrus flavonoid displaying potent physiological activity.

T. Kan, S. Itai, Y. Iwao, 2016, Acta crystallographica. Section C, Structural chemistry.

Characterization of a Caffeic Acid 8-O-Methyltransferase from Citrus and Its Function in Nobiletin Biosynthesis.

H. Fujii, T. Kan, T. Endo, 2021, Journal of agricultural and food chemistry.

Synthesis of double-13C-labeled imidazole derivatives

T. Asakawa, T. Kan, H. Kawagishi, 2018, Tetrahedron Letters.

Internal activation of acrylate-type dienophiles for the Diels-Alder reaction. Stereoselective synthesis of conformationally constrained glutamate analogs

T. Kan, T. Nakajima, Y. Ohfune, 1998 .

Synthesis of biotinylated photoaffinity probes based on arylsulfonamide gamma-secretase inhibitors.

T. Iwatsubo, T. Kan, T. Tomita, 2006, Bioorganic & Medicinal Chemistry Letters.

Sulindac sulfide is a noncompetitive gamma-secretase inhibitor that preferentially reduces Abeta 42 generation.

T. Iwatsubo, T. Kan, T. Tomita, 2003, The Journal of biological chemistry.

Stereocontrolled synthesis of (+)-methoxyphenylkainic acid and (+)-phenylkainic acid.

T. Asakawa, T. Kan, T. Wakimoto, 2011, Organic letters.

Synthesis of Biologically Active Natural Products by Means of C-H Insertion Reaction

T. Kan, 2014 .

A Fairy Chemical, Imidazole-4-carboxamide, is Produced on a Novel Purine Metabolic Pathway in Rice

R. Motohashi, Hirofumi Hirai, T. Asakawa, 2019, Scientific Reports.

PET imaging of nobiletin based on a practical total synthesis.

N. Harada, H. Tsukada, N. Oku, 2011, Chemical communications.

A Short-Step Asymmetric Synthesisof Dehydrodiconiferyl Alcohol via C-H InsertionReaction

Y. Hamashima, T. Asakawa, T. Kan, 2012 .

Enantioselective synthesis of SB-203207.

Yuichiro Kawamoto, T. Asakawa, T. Kan, 2014, Organic letters.

Stereocontrolled total synthesis of (+)-UCS1025A.

Y. Hamashima, T. Asakawa, T. Kan, 2012, Angewandte Chemie.

Total synthesis of ecteinascidin 743.

T. Kan, T. Fukuyama, A. Yanagisawa, 2002, Journal of the American Chemical Society.

Regulation of Staphylococcal Enterotoxin-Induced Inflammation in Spleen Cells from Diabetic Mice by Polyphenols

T. Kan, S. Masuda, Y. Shimamura, 2023, Microorganisms.

Practical total syntheses of acromelic acids A and B.

Y. Hamashima, T. Asakawa, T. Kan, 2014, Organic letters.