P. Gaffney

发表

Gadolinium‐modulated 19F signals from perfluorocarbon nanoparticles as a new strategy for molecular imaging

S. Caruthers, P. Winter, A. Neubauer, 2008, Magnetic resonance in medicine.

Conquering the dark side: colloidal iron oxide nanoparticles.

S. Caruthers, D. Pan, G. Hu, 2009, ACS nano.

Enhanced detection of thrombi with a novel fibrin-targeted magnetic resonance imaging agent.

C H Lorenz, S A Wickline, C. Lorenz, 1998, Academic radiology.

Fibrin-targeted perfluorocarbon nanoparticles for targeted thrombolysis.

S A Wickline, G. Hu, S. Wickline, 2007, Nanomedicine.

Sensitive and efficient detection of thrombus with fibrin-specific manganese nanocolloids.

Dipanjan Pan, Patrick J. Gaffney, Samuel A. Wickline, 2009, Chemical communications.

Haemoglobin Hammersmith (beta-42 (CDI) Phe replaced by ser).

P. Gaffney, J. Dacie, N. Shinton, 1967, Nature.

Molecular photoacoustic tomography with colloidal nanobeacons.

Xinmai Yang, Manojit Pramanik, Lihong V. Wang, 2009, Angewandte Chemie.

A family of textilinin genes, two of which encode proteins with antihaemorrhagic properties

D. Winzor, M. Lavin, P. Gaffney, 2002, British journal of haematology.

Ligand-directed nanobialys as theranostic agent for drug delivery and manganese-based magnetic resonance imaging of vascular targets.

S. Caruthers, D. Pan, G. Hu, 2008, Journal of the American Chemical Society.

Targeted PARACEST nanoparticle contrast agent for the detection of fibrin

Kejia Cai, S. Caruthers, K. Cai, 2006, Magnetic resonance in medicine.

Plasminogen activators in experimental colorectal neoplasia: a role in the adenoma-carcinoma sequence?

P. Gaffney, M. Lewin, M. Mahmoud, 1987, Gut.

The Haemostatic Balance – Astrup Revisited

P. Gaffney, C. Whitton, T. Edgell, 1999, Pathophysiology of Haemostasis and Thrombosis.

Resistance of porcine blood clots to lysis relates to poor activation of porcine plasminogen by tissue plasminogen activator

M. Lavin, P. Gaffney, P. Masci, 2006, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Haemoglobin Sogn (β14 Arginine) A New Haemoglobin Variant

P. Gaffney, H. Lehmann, E. Monn, 2009 .

Nomenclature of Quantities and Units in Thrombosis and Haemostasis (Recommendation 1993)

M. Blombäck, C. Francis, B. Dahlbäck, 1994, Thrombosis and Haemostasis.

The binding of glu- and lys-plasminogens to fibrin and their subsequent effects on fibrinolysis.

P. Gaffney, P. Masci, A. Whitaker, 1980, Thrombosis research.

A fibrin-specific thrombolytic nanomedicine approach to acute ischemic stroke.

S. Caruthers, G. Hu, Huiying Zhang, 2011, Nanomedicine.

Fibrin degradation product (FnDP) assays: analysis of standardization issues and target antigens in plasma

P. Gaffney, E. Tarelli, T. Edgell, 1995, British journal of haematology.

The International and “NIH” Units for Thrombin - How Do They Compare?

P. Gaffney, T. Edgell, 1995, Thrombosis and Haemostasis.

Preparation and stability of a highly purified human thrombin standard.

P. Gaffney, M. Seghatchian, M. Miller-Andersson, 1980, Thrombosis research.

A Collaborative Study to Establish the 2nd International Standard for Fibrinogen, Plasma

P. Gaffney, A. Hubbard, D. Sands, 2000, Thrombosis and Haemostasis.

The effect of anticoagulation with subcutaneously delivered polyethylene glycol conjugated hirudin and recombinant tissue plasminogen activator on recurrent stenosis in the rabbit double-balloon injury model.

Alberto Smith, K. Burnand, J. Humphries, 2004, Thrombosis research.

Routine measurement of fibrinogen concentration: Problems exaggerated

P. Gaffney, 1993 .

Differences between neonates and adults in tissue-type-plasminogen activator (t-PA)-catalyzed plasminogen activation with various effectors and in carbohydrate sequences of fibrinogen chains.

A. Dell, H. Morris, P. Corran, 2001, Thrombosis research.

In Vivo Penetration of Experimentally Produced Clots by Monoclonal Antibodies

P. Gaffney, F. McEvoy, P. Webbon, 2000, Thrombosis and Haemostasis.

A neoantigenic determinant in the D-dimer fragment of fibrin.

P. Gaffney, W. Nieuwenhuizen, P. G. Gritsenko, 2002, Thrombosis research.

The International Standard for Plasminogen Activator Inhibitor-1 (PAI-1) Activity

P. Gaffney, T. Edgell, 1996, Thrombosis and Haemostasis.

A Collaborative Study to Establish the 2nd International Standard for Tissue Plasminogen Activator (t-PA)

P. Gaffney, A. Curtis, 1987, Thrombosis and Haemostasis.

Human serum cholinesterase. I. Partial purification andnature of the heterogeneity of this system.

P. Gaffney, 1970, Biochimica et biophysica acta.

Imaging of human thrombi in the rabbit jugular vein: I: Comparison of two fibrin-specific monoclonal antibodies.

P. Gaffney, P. Webbon, P. Gascoine, 1989, Thrombosis research.

Ultra-rapid preparation of milligram quantities of the purified polypeptide chains of human fibrinogen.

P. Corran, P. Gaffney, S. Raut, 1994, Journal of chromatography. B, Biomedical applications.

Diabetes mellitus as a hypercoagulable state: its relationship with fibrin fragments and vascular damage.

P. Gaffney, I. Alava, J. Navarro, 1987, Thrombosis research.

Changes in fibrinolysis in the intensive care patient.

P. Gaffney, L. Landín, J. Navarro, 1987, Thrombosis research.

Subunit structure of the plasmin-induced degradation products of crosslinked fibrin.

P. Gaffney, M. Brasher, P. J. Gaffney, 1973, Biochimica et biophysica acta.

Tissue plasminogen activator for thrombolytic therapy: expectation versus reality.

P. Gaffney, 1992, Journal of the Royal Society of Medicine.

A monoclonal antibody which recognises an epitopic region unique to the intact fibrin polymeric structure

V. Ploplis, P. Gaffney, J. Pleasants, 1993 .

Some observations on the release of extrinsic and intrinsic plasminogen activators during exercise in man.

P. Gaffney, N. Marsh, 1980, Haemostasis.

Unreliability of chromogenic substrates for assay of the clotting activity of thrombin.

T. Kirkwood, P. Gaffney, M. Miller-Andersson, 1978, Haemostasis.

An experimental clot model in sheep; generation of a heterologous clot and its detection in vivo using venography and (125)I labelled fibrinogen.

P. Gaffney, F. McEvoy, P. Webbon, 2002, Research in veterinary science.

Comparison of Textilinin-1 with Aprotinin as Serine Protease Inhibitors and as Antifibrinolytic Agents

M. Trabi, M. Lavin, P. Gaffney, 2006, Pathophysiology of Haemostasis and Thrombosis.

Textilinins from Pseudonaja textilis textilis. Characterization of two plasmin inhibitors that reduce bleeding in an animal model

D. Winzor, M. Lavin, D. Watters, 2000, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

The sulphite precipitation method for fibrinogen measurement; its use on small samples in the presence of fibrinogen degradation products.

P. Gaffney, M. Rampling, 1976, Clinica chimica acta; international journal of clinical chemistry.

Characterisation of a soluble D dimer-E complex in crosslinked fibrin digests.

V. Kakkar, P. Gaffney, D. Lane, 1975, Thrombosis research.

Monoclonal antibodies to crosslinked fibrin degradation products (XL‐FDP) I. CHARACTERIZATION AND PRELIMINARY EVALUATION IN PLASMA

R. Thorpe, P. Gaffney, M. Spitz, 1988, British journal of haematology.

Development of an ELISA for the quantification of fibrin in canine tumours.

P. Gaffney, F. McEvoy, S. Raut, 1999, Thrombosis research.

Detection of fibrin in canine neoplasia.

P. Gaffney, F. McEvoy, P. Webbon, 1996, The British veterinary journal.

Serpin-serine protease binding kinetics: alpha 2-antiplasmin as a model inhibitor.

P. Gaffney, C. Longstaff, 1991, Biochemistry.

An International Collaborative Study to Investigate Standardisation of Hirudin Potency

P. Gaffney, C. Longstaff, Melvin H. L. Wong, 1993, Thrombosis and Haemostasis.

Quantitative intravascular ultrasound. Demonstration using a novel site targeted acoustic contrast agent

S. Wickline, P. Gaffney, M. Scott, 1995, 1995 IEEE Ultrasonics Symposium. Proceedings. An International Symposium.

Fibrin crosslinks and lysis rates.

P. Gaffney, A. Whitaker, A. Whitaker, 1979, Thrombosis research.

A Collaborative Study of a Proposed International Standard for Tissue Plasminogen Activator (t-PA)

P. Gaffney, A. Curtis, 1985, Thrombosis and Haemostasis.

A Performance Evaluation of Commercial Fibrinogen Reference Preparations and Assays for Clauss and PT-derived Fibrinogen

G. Lowe, P. Gaffney, P. Rigsby, 2002, Thrombosis and Haemostasis.

Characteristics of Lipase-Rich Fractions of Milk Protein

W. J. Harper, P. Gaffney, I. A. Gould, 1968 .

Distribution of lipase among components of a water extract of rennet casein.

W. J. Harper, P. Gaffney, I. A. Gould, 1966, Journal of dairy science.

Distinction between fibrinogen and fibrin degradation products in plasma.

P. Gaffney, P. J. Gaffney, 1975, Clinica chimica acta; international journal of clinical chemistry.

THE OCCURRENCE AND CLINICAL RELEVANCE OF FIBRIN FRAGMENTS IN BLOOD

P. Gaffney, 1983, Annals of the New York Academy of Sciences.

Interaction of heparin with fibrinogen using surface plasmon resonance technology: investigation of heparin binding site on fibrinogen.

P. Gaffney, S. Raut, 1996, Thrombosis research.

An Experimental Model for the Study of Venous Thrombosis in Vivo

M. Scully, P. Gaffney, T. K. Day, 1974, Thrombosis and Haemostasis.

Unreliability of Current Serum Fibrin Degradation Product (FDP) Assays

P. Gaffney, M. Perry, 1985, Thrombosis and Haemostasis.

The Role of the Monocyte in the Generation and Dissolution of Arterial and Venous Thrombi

J. Humphries, P. Gaffney, K. Burnand, 1998 .

Influence of various structural domains of fibrinogen and fibrin on the potentiation of plasminogen activation by recombinant tissue plasminogen activator

F. Castellino, P. Gaffney, T. Urano, 1989, Journal of protein chemistry.

Localisation of carbohydrate in the subunits of human fibinogen and its plasmin induced fragments.

P. Gaffney, 1972, Biochimica et biophysica acta.

MOLECULAR PATHOLOGY OF THE MULTIPLE FORMS OF FIBRINOGEN AND ITS FRAGMENTS

P. Gaffney, 1975 .

Plasma Fibrinogen and its Fragments during Streptokinase Treatment

P. Gaffney, M. Allington, C. Chesterman, 1974, British journal of haematology.

A Collaborative Study to Establish a Standard for High Molecular Weight Urinary-Type Plasminogen Activator (HMW/u-PA)

A. Heath, P. Gaffney, 1990, Thrombosis and Haemostasis.

Activation of the intrinsic fibrinolytic pathway with normal extrinsic responses in a patient undergoing gastric surgery

P. Gaffney, P. Grant, C. Prentice, 1990 .

Acute Changes in Blood Glucose Concentration do not Promote Thrombin Generation or Fibrin Breakdown in Type 1 Diabetes

P. Gaffney, P. Grant, M. Stickland, 1988, Diabetic Medicine.

Heparin and a low molecular weight fraction enhances thrombolysis and by this pathway exercises a protective effect against thrombosis.

P. Gaffney, C. Doutremépuich, N. Marsh, 1983, Thrombosis research.

Increased release of tissue plasminogen activator and its inhibitor in human parotid saliva upon stimulation.

I. Johansson, F. Lagerlöf, P. Gaffney, 1992, Acta physiologica Scandinavica.

Quantitative immuno-recognition by a radial diffusion technique.

T. Kirkwood, P. Gaffney, M. Mahmoud, 1977, Journal of immunological methods.

Evaluation of the Fibrin Binding Profile of two Anti-fibrin Monoclonal Antibodies

P. Gaffney, S. Raut, 1996, Thrombosis and Haemostasis.

The relationship between plasma vasopressin and changes in coagulation and fibrinolysis during hip surgery.

P. Gaffney, P. Grant, C. Prentice, 1988, Thrombosis research.

A novel radioimmunometric approach to the assay of components of human haemostasis: 1. Assay of plasma fibrinopeptide A levels.

P. Gaffney, M. Spitz, C. A. Fossati, 1980, Thrombosis research.

Giant fibrin fragments derived from crosslinked fibrin: structure and clinical implication.

P. Gaffney, M. Mahmoud, F. Joe, 1980, Thrombosis research.

A Pig Collagen Peptide Fraction. A Unique Material for Maintaining Biological Activity During Lyophilization and During Storage in the Liquid State

P. Gaffney, P. Dawson, T. Edgell, 1996, The Journal of pharmacy and pharmacology.

The tissue plasminogen activator and urokinase response in vivo during natural resolution of venous thrombus.

L. Bobrow, K. Burnand, P. Gaffney, 1995, Journal of vascular surgery.

The relative inhibition by α2-antiplasmin and plasminogen activator inhibitor-1 of clot lysis in vitro

J. Paramo, P. Gaffney, P. Gascoine, 1990 .

Plasminogen activators inexperimental colorectal neoplasia: arole intheadenoma-carcinoma sequence?

P. Gaffney, M. Lewin, M. Mahmoud, 1987 .

Fibrin subunits in venous and arterial thromboembolism.

M. Scully, P. Gaffney, V. Kakkar, 1976, Cardiovascular research.

Plasma levels of fibrin fragments in men with myocardial infarction.

P. Gaffney, P. Sweetnam, M. Perry, 1986, Thrombosis research.

Tissue plasminogen activators in breast cancer.

K. Burnand, P. Gaffney, G. Layer, 1987, Thrombosis research.

A novel site-targeted ultrasonic contrast agent with broad biomedical application.

J. G. Miller, J G Miller, S A Wickline, 1996, Circulation.

Targeted acoustic contrast agents: New opportunities for ultrasound in medical diagnosis and therapy

J. H. Rose, S. Wickline, G. Lanza, 1998 .

Generation and partial characterization of five monoclonal antibodies with high affinities for fibrin

P. Gaffney, P. Tymkewycz, L. J. C. Kempsford, 1993, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Screening for Fibrin Specific Monoclonal Antibodies: The Development of a New Procedure

P. Gaffney, D. Hockley, L. Creighton-Kempsford, 1992, Thrombosis and Haemostasis.

D-dimer. History of the discovery, characterisation and utility of this and other fibrin fragments

P. Gaffney, 1993 .

Plasminogen activators in human colorectal neoplasia.

P. Gaffney, M. Lewin, M. Mahmoud, 1986, British medical journal.

The lysis of crosslinked human fibrin by plasmin yields initially a single molecular complex, D dimer-E.

P. Gaffney, F. Joe, 1979, Thrombosis research.

The Effect of Pentosan Polysulphate (SP54) on the Fibrinolytic Enzyme System - A Human Volunteer and Experimental Animal Study

P. Gaffney, M. Mahmoud, P. Peyser, 1985, Thrombosis and Haemostasis.

A Comparison of Pentosan Polysulphate and Heparin II: Effects of Subcutaneous Injection

P. Gaffney, S. Williams, T. Barrowcliffe, 1982, Thrombosis and Haemostasis.

An in vitro circulation model for thrombosis; influence of circulating plasmas on the binding of monoclonal antibodies to human fibrin clots

P. Gaffney, F. McEvoy, P. Webbon, 1995 .

Characterisation of the chains of human fibrinogen isolated by perfusion chromatography using fibrin specific monoclonal antibodies.

P. Corran, P. Gaffney, S. Raut, 1995, Thrombosis research.

Differences between neonates and adults in the urokinase-plasminogen activator (u-PA) pathway of the fibrinolytic system.

M. Zenker, P. Gaffney, M. Ries, 2000, Thrombosis research.

Letters to the EditorF.D.P.

P. Gaffney, 1972 .

Effectors of the activation of human [Glu1]plasminogen by human tissue plasminogen activator.

F. Castellino, P. Gaffney, T. Urano, 1988, Biochemistry.

Fibrinolysis: Current Prospects

P. Gaffney, E. Plow, F. J. Gastellino, 1988 .

Presence of a fast-acting specific inhibitor of plasminogen activator in human parotid saliva.

P. Gaffney, A. Kjaeldgaard, M. Kjaeldgaard, 1989, Acta physiologica Scandinavica.

Textilinin‐1, an alternative anti‐bleeding agent to aprotinin: Importance of plasmin inhibition in controlling blood loss

M. Trabi, M. Lavin, P. Gaffney, 2009, British journal of haematology.

The activation of human [Glu1]plasminogen by human single-chain urokinase

F. Castellino, P. Gaffney, T. Urano, 1988 .

Bioimmunoassay (BIA) of Tissue Plasminogen Activator (t-PA) and Its Specific Inhibitor (t-PA/INH)

P. Gaffney, M. Mahmoud, P J Gaffney, 1985, Thrombosis and Haemostasis.

Tissue and urokinase plasminogen activators in the environs of venous and ischaemic leg ulcers

K. Burnand, P. Gaffney, M. Stacey, 1993, The British journal of surgery.

Differences between neonates and adults in carbohydrate sequences and reaction kinetics of plasmin and alpha(2)-antiplasmin.

Anne Dell, Howard R Morris, Martin Zenker, 2002, Thrombosis research.

MOLECULAR ASPECTS OF FIBRINOLYSIS

P. Gaffney, 1981, Annals of the New York Academy of Sciences.

Thrombosis: a molecular approach to therapy

P. Gaffney, 1981, Nature.

Breakdown products of fibrin and fibrinogen: molecular mechanisms and clinical implications

P. Gaffney, 1980, Journal of clinical pathology. Supplement.

Discussion on the meeting on ‘Statistical modelling and analysis of genetic data’

Terence P. Speed, Peter Donnelly, Dirk Husmeier, 2002 .

Negative Cross-Resistance: History, Present Status, and Emerging Opportunities

Aaron J. Gassmann, Barry Robert Pittendrigh, Patrick J. Gaffney, 2013 .

Negative Cross-Resistance: Past, Present, and Future Potential

Barry Robert Pittendrigh, Joseph E. Huesing, Patrick J. Gaffney, 2007 .

Hyper-susceptibility to deltamethrin in parats-1 DDT resistant Drosophila melanogaster

R. Reenan, B. Pittendrigh, P. Gaffney, 2004 .

Comparative mapping of loci controlling winter survival and related traits in oilseed Brassica rapa and B. napus

B. Yandell, C. Kole, P. Gaffney, 2002, Molecular Breeding.

The activation of human [Glu1]plasminogen by human single-chain urokinase.

F. Castellino, P. Gaffney, T. Urano, 1988, Archives of biochemistry and biophysics.

Haemoglobin O Arab in Egypt and Aden: possible errors resulting from the use of haemoglobin variants as genetic markers in population surveys.

P. Gaffney, H. Lehmann, R. Huntsman, 1967, Zeitschrift fur Morphologie und Anthropologie.

A Coagulant Enzyme from Gaboon-Viper Venom: Some Aspects of its Mode of Action

P. Gaffney, N. Marsh, B. Whaler, 1973 .

Novel MRI Contrast Agent for Molecular Imaging of Fibrin: Implications for Detecting Vulnerable Plaques

S A Wickline, S. Flacke, P. Winter, 2001, Circulation.

The effect of pentosan polysulphate (SP54) on the human fibrinolytic system.

P. Gaffney, N. Marsh, 1986, Folia haematologica.

Identification of D-Dimer-E Complex in Disseminated Intravascular Coagulation (DIC)

P. Gaffney, P. Masci, A. Whitaker, 1979, Thrombosis and Haemostasis.

Snake venoms and haemostasis: some suggested mechanisms of action.

P. Gaffney, N. Marsh, P. Talalak, 1979, Southeast Asian Journal of Tropical Medicine and Public Health.

A Collaborative Study to Establish the Second International Standard for Streptokinase

A. Heath, P. Gaffney, 1990, Thrombosis and Haemostasis.

Problems in the assay of thrombin using synthetic peptides as substrates.

T. Kirkwood, P. Gaffney, M. Brasher, 1977, Thrombosis research.

Standards in Fibrinolysis – Current Status and Future Challenges

P. Gaffney, 1995, Thrombosis and Haemostasis.

Plasmin Potency Estimates: Influence of the Substrate Used in Assay

P. Gaffney, R. Philo, 1981, Thrombosis and Haemostasis.

A structural aspect of human fibrinogen suggested by its plasmin degradation

P. Gaffney, P. Dobos, 1971, FEBS letters.

The role of the monocyte in the generation and dissolution of arterial and venous thrombi.

J. Humphries, P. Gaffney, K. Burnand, 1998, Cardiovascular surgery.

Exercise-Induced Fibrinolysis – Fact or Fiction?

P. Gaffney, N. Marsh, 1982, Thrombosis and Haemostasis.

Origin of urinary fibrin-fibrinogen degradation products in renal glomerular disease.

P. Gaffney, J. Blainey, C. L. Hall, 1979, Nephron.

Subunit relationships between fibrinogen and fibrin degradation products

P. Gaffney, 1973 .

Molecular aspects of fibrin clot solubilization.

P. Gaffney, 1971, Nature: New biology.

Nature of the high molecular weight fraction of fibrinolytic digests of human fibrinogen.

P. Gaffney, G. Jamieson, 1968, Biochimica et biophysica acta.

The molecular and functional condition of plasma fibrinogen during thrombolytic therapy with streptokinase (SK)

P. Gaffney, 1973 .

A Collaborative Study to Establish an International Standard for Alpha-Thrombin

A. Heath, P. Gaffney, J. Fenton II, 1992, Thrombosis and Haemostasis.

International Collaborative Study for the Establishment of the Second International Reference Preparation of Plasmin

P. Gaffney, M. V. Mussett, 1983, Thrombosis and Haemostasis.

Standard for Human Thrombin

P. Gaffney, D. Bangham, I. Robertson, 1975, Thrombosis and Haemostasis.

Plasminogen activators and inhibitors in amniotic fluid

P. Gaffney, A. Kjaeldgaard, B. Åstedt, 1989 .

A novel serine protease inhibitor from the Australian brown snake, Pseudonaja textilis textilis: Inhibition kinetics

P. Gaffney, P. Masci, A. Whitaker, 1995 .

Monoclonal antibodies for the detection of thrombosis.

P. Gaffney, P. Gascoine, P. Tymkewycz, 1990, Advances in experimental medicine and biology.

Assay methodology for urokinase: its use in assessing the composition of mixtures of high- and low-molecular weight urokinase.

P. Gaffney, R. Philo, 1981, Thrombosis research.

A Standard for Human Plasmin

T. Kirkwood, P. Gaffney, P. Campbell, 1975, Thrombosis and Haemostasis.

The Establishment of a Standard for Plasminogen (Glu-Type)

P. Gaffney, A. Curtis, 1984, Thrombosis and Haemostasis.

The Stability of Tissue Plasminogen Activator (t-PA)

P. Gaffney, P. Campbell, A. Curtis, 1983, Thrombosis and Haemostasis.

Single shot intrasplenic immunization: an advantageous procedure for production of monoclonal antibodies specific for human fibrin fragments.

R. Thorpe, P. Gaffney, M. Spitz, 1984, Hybridoma.

Deterministic modeling of negative cross-resistance strategies for use in transgenic host-plant resistance.

B. Pittendrigh, P. Gaffney, L. Murdock, 2000, Journal of theoretical biology.

"Active" refuges can inhibit the evolution of resistance in insects towards transgenic insect-resistant plants.

D. Onstad, R. Roush, B. Pittendrigh, 2004, Journal of theoretical biology.

Pesticide resistance: can we make it a renewable resource?

B. Pittendrigh, P. Gaffney, 2001, Journal of theoretical biology.

The Haemophiliac in the Eighties

R. Abbate, G. Gensini, H. Hemker, 1982 .

Plasminogen activators in human colorectal neoplasia

P. Gaffney, M. Lewin, M. Mahmoud, 1986 .

Investigation by HPLC of the Catabolism of Recombinant Tissue Plasminogen Activator in the Rat

L. Creighton, P. Gaffney, S. Poole, 1988, Thrombosis and Haemostasis.

Collaborative Study of a Proposed International Standard for Plasma Fibrinogen Measurement

P. Gaffney, Melvin H. L. Wong, M. Y. Wong, 1992, Thrombosis and Haemostasis.

Thrombolytic Profiles of Clot-Targeted Plasminogen Activators

T. Tollenaere, M. Dewerchin, H. Lijnen, 2005 .

Thrombolytic Profiles of Clot‐Targeted Plasminogen Activators Parameters Determining Potency and Initial and Maximal Rates

M. Dewerchin, H. Lijnen, P. Gaffney, 1993, Circulation.

Bioavailability in Rats of Human Recombinant Tissue Plasminogen Activator After Subcutaneous and Intramuscular Injection

P. Gaffney, S. Poole, S. Hanley, 1986, Thrombosis and Haemostasis.

Soluble high-molecular-weight E fragments in the plasmin-induced degradation products of cross-linked human fibrin.

P. Gaffney, D. Lane, M. Brasher, 1975, Clinical science and molecular medicine.

The influence of various combinations of plasminogen and streptokinase on fibrinolysis. II. A mechanistic study.

P. Gaffney, A. Whitaker, E. A. Rowe, 1982, Haemostasis.

Kinetics of plasmin activation of single chain urinary-type plasminogen activator (scu-PA) and demonstration of a high affinity interaction between scu-PA and plasminogen.

P. Gaffney, C. Longstaff, A. M. Clough, 1992, The Journal of biological chemistry.

Activation of plasminogen as a feature in its assay.

T. Kirkwood, P. Gaffney, M. Brasher, 1977, Haemostasis.

Fibrin Degradation Products

P. Gaffney, 2001, Annals of the New York Academy of Sciences.

Effects of early plasmin digests of fibrinogen on isometric tension development in isolated rings of rat pulmonary artery.

P. McLoughlin, P. Gaffney, S. Raut, 1996, Thrombosis Research.

Further Physicochemical and Immunological Data Concerning the D-Dimer Complex

P. Gaffney, F. Joe, M. Brasher, 1977, Thrombosis and Haemostasis.

Heterogeneity of human fibrinogen.

P. Gaffney, 1971, Nature: New biology.

Standardization of plasminogen assays.

P. Gaffney, 1988, Haemostasis.

UROKINASE VERSUS TISSUE PLASMINOGEN ACTIVATOR IN PULMONARY EMBOLISM

J. Henkin, P. Gaffney, A. Sasahara, 1988, The Lancet.

Molecular Imaging of Human Thrombus with Computed Tomography

Himanshu P. Shukla, Patrick J. Gaffney, Samuel A. Wickline, 2005 .

High and constant plasma levels of tissue plasminogen activator and PEG-hirudin can be achieved by subcutaneous delivery.

J. Humphries, P. Gaffney, K. Burnand, 1997, Thrombosis research.

Roles for chloride ion and fibrinogen in the activation of [Glu1]plasminogen in human plasma.

F. Castellino, P. Gaffney, T. Urano, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Computed tomography in color: NanoK-enhanced spectral CT molecular imaging.

J. Schlomka, E. Roessl, R. Proksa, 2010, Angewandte Chemie.

Fibrin degradation products. A review of structures found in vitro and in vivo.

P. Gaffney, 2001, Annals of the New York Academy of Sciences.

The Rapid Fibrin Plate – a Method for Plasminogen Activator Assay

P. Gaffney, N. Marsh, 1977, Thrombosis and Haemostasis.

Studies on the mechanism of binding of serpins and serine proteases.

P. Gaffney, C. Longstaff, 1992, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Urokinase: the Enzyme Responsible for Invasion and Metastasis in Human Breast Carcinoma?

K. Burnand, P. Gaffney, G. Layer, 1987 .

LIPASE ACTIVITY IN SOMATIC CELLS FROM SEPARATOR SLIME.

W. J. Harper, P. Gaffney, 1965, Journal of dairy science.

Fibrin(-ogen) interactions with plasmin.

P. Gaffney, 1977, Haemostasis.

Residual enzyme activity in the serum of a homozygote for the silent pseudocholinesterase gene.

P. Gaffney, H. Lehmann, 1969, Human heredity.

The human pseudocholinesterase system.

P. Gaffney, 1968, The Biochemical journal.

Some aspects of the molecular pathology of thrombosis and haemorrhage

P. Gaffney, 1984, Irish journal of medical science.

Improvements in the ultrasonic contrast of targeted perfluorocarbon nanoparticles using an acoustic transmission line model

S. Wickline, G. Lanza, P. Gaffney, 2002, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

Quantitative “magnetic resonance immunohistochemistry” with ligand‐targeted 19F nanoparticles

Patrick J. Gaffney, Samuel A. Wickline, Patrick M. Winter, 2004 .

Improved molecular imaging contrast agent for detection of human thrombus

Sheng-Kwei Song, Shelton D Caruthers, Samuel A Wickline, 2003, Magnetic resonance in medicine.

High-frequency ultrasonic detection of thrombi with a targeted contrast system.

J. G. Miller, J G Miller, S A Wickline, 1997, Ultrasound in medicine & biology.

Plasminogen activation by recombinant tissue plasminogen activator and potentiation by fibrin: a refined kinetic analysis

P. Gaffney, N. Willmott, 1995 .

High Sensitivity: High-Resolution SPECT-CT/MR Molecular Imaging of Angiogenesis in the Vx2 Model

S. Caruthers, T. Williams, A. Schmieder, 2009, Investigative radiology.

Temperature dependence of ultrasonic enhancement with a site-targeted contrast agent.

S A Wickline, S. Wickline, G. Lanza, 2001, The Journal of the Acoustical Society of America.

Non-enzymatic glucosylation of fibrinogen.

P. Gaffney, S. Thorpe, B. Mcverry, 1981, Haemostasis.

Quantitative "magnetic resonance immunohistochemistry" with ligand-targeted (19)F nanoparticles.

Samuel A Wickline, Gregory M Lanza, Patrick M Winter, 2004, Magnetic resonance in medicine.

In vitro characterization of a novel, tissue-targeted ultrasonic contrast system with acoustic microscopy.

J. G. Miller, J G Miller, S A Wickline, 1998, The Journal of the Acoustical Society of America.

High‐resolution MRI characterization of human thrombus using a novel fibrin‐targeted paramagnetic nanoparticle contrast agent

Sheng-Kwei Song, S. Wickline, G. Lanza, 2000, Magnetic resonance in medicine.

In Vitro Demonstration Using 19F Magnetic Resonance to Augment Molecular Imaging With Paramagnetic Perfluorocarbon Nanoparticles at 1.5 Tesla

Shelton D Caruthers, Samuel A Wickline, Gregory M Lanza, 2006, Investigative radiology.

Synthesis of NanoQ, a copper-based contrast agent for high-resolution magnetic resonance imaging characterization of human thrombus.

S. Caruthers, D. Pan, G. Hu, 2011, Journal of the American Chemical Society.

Time evolution of enhanced ultrasonic reflection using a fibrin-targeted nanoparticulate contrast agent.

Patrick J. Gaffney, Jon N. Marsh, Samuel A. Wickline, 2000 .

Time-evolution of enhanced ultrasonic reflection using a fibrin-targeted nanoparticulate contrast agent

S. Wickline, G. Lanza, P. Gaffney, 2000, 2000 IEEE Ultrasonics Symposium. Proceedings. An International Symposium (Cat. No.00CH37121).

Monoclonal Antibodies to Human Fibrin: Interaction with other Animal Fibrins

P. Gaffney, P J Gaffney, F. McEvoy, 1996, Thrombosis and Haemostasis.

Fibrinolysis : current fundamental and clinical concepts

P. Gaffney, Ş. Balkuv-Ulutin, African Division, 1978 .

PGM Guidelines for Description of Criteria and Methods for Testing of Specificity of Assay Methods for Quantities in the Fibrinolytic System

C. Francis, P. Declerck, J. Jespersen, 2000, EJIFCC.

ANCROD AND ITS ACTIVITIES

P. Gaffney, M. Brasher, 1973 .

Detecting vascular biosignatures with a colloidal, radio-opaque polymeric nanoparticle.

Samuel A Wickline, Gregory M Lanza, Dipanjan Pan, 2009, Journal of the American Chemical Society.

The distribution of carbohydrate in the plasmin resistant core fragments (D,E) of human fibrinogen.

P. Gaffney, D. Pepper, H. Blume, 1974, Biochimica et biophysica acta.

IMMUNOASSAYS FOR SINGLE CHAIN URINARY-TYPE PLASMINOGEN ACTIVATOR (SCUPA) IN PLASMA AND IN CELL CULTURE SUPERNATANTS

H. Scheuerlein, P. Gaffney, F. Hammerschmidt, 1987, Thrombosis and Haemostasis.

Effects of reducing LDL and increasing HDL with gemfibrozil in experimental coronary lesion development and thrombotic risk.

L. Badimón, P. Gaffney, T. Royo, 1998, Atherosclerosis.

Aprotinin reduces cardiopulmonary bypass‐induced blood loss and inhibits fibrinolysis without influencing platelets

A. Michelson, P. Gaffney, C. Goodchild, 1993, British journal of haematology.

Breakdown products of fibrin and fibrinogen: molecular mechanisms and clinical implications

P. Gaffney, 1980, Journal of clinical pathology. Supplement.

Heterogeneity of fibrin polymerization inhibitor.

P. Gaffney, G. Jamieson, 1966, Biochimica et Biophysica Acta.

Urokinase: the Enzyme Responsible for Invasion and Metastasis in Human Breast Carcinoma?

K. Burnand, P. Gaffney, G. Layer, 1987 .

Sensitive and direct assays for functionally active plasminogen activators (tissue-type and urokinase-type) in plasma.

A. Heath, P. Gaffney, M. Mahmoud-alexandroni, 1989, American journal of clinical pathology.

The relationship of plasminogen activators and oncogenes to tumour invasion.

P. Gaffney, M. Lewin, M. Mahmoud, 1990, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

The ability of fibrinogen fragments to support ADP-induced platelet aggregation.

P. Gaffney, M. Mahmoud, J. Holt, 1979, Thrombosis research.

International Collaborative Study on the Assay of Commercially Available High and Low Molecular Weight Urokinases

T. Kirkwood, P. Gaffney, G. Murano, 1981, Thrombosis and Haemostasis.

Report of the Task Force on Standards for Thrombin and Thrombin-Like Enzymes

P. Gaffney, 1977, Thrombosis and Haemostasis.