H. Gewirtz

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In vivo 18F-fluorodeoxyglucose positron emission tomography imaging provides a noninvasive measure of carotid plaque inflammation in patients.

Ahmed Tawakol, Thomas J Brady, Henry Gewirtz, 2006, Journal of the American College of Cardiology.

Noninvasive in vivo measurement of vascular inflammation with F-18 fluorodeoxyglucose positron emission tomography

Ahmed Tawakol, James E. Muller, Udo Hoffmann, 2005, Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.

Prognostic value of coronary CTA vs. exercise treadmill testing: results from the Partners registry.

Nishant R. Shah, R. Blankstein, S. Abbara, 2015, European heart journal cardiovascular Imaging.

Integration of clinical and imaging data to predict the presence of coronary artery disease with the use of neural networks

James A Scott, T. Yasuda, H. Gewirtz, 2004, Coronary artery disease.

Adenosine-induced stress myocardial perfusion imaging using dual-source cardiac computed tomography.

R. Cury, G. Feuchtner, D. Okada, 2009, Journal of the American College of Cardiology.

Mechanism of persistent S-T segment elevation after anterior myocardial infarction.

E. R. Smith, P. Rautaharju, H. Wolf, 1979, The American journal of cardiology.

Anatomic versus physiologic assessment of coronary artery disease. Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making.

Juhani Knuuti, Robert Bober, Vasken Dilsizian, 2013, Journal of the American College of Cardiology.

Quantitative assessment of the effects of a fixed 50% coronary artery stenosis on regional myocardial flow reserve and transmural distribution of blood flow.

H. Gewirtz, D. Williams, A. S. Most, 1983, Journal of the American College of Cardiology.

Production of a critical coronary arterial stenosis in closed chest laboratory animals. Description of a new nonsurgical method based on standard cardiac catheterization techniques.

H. Gewirtz, A. S. Most, 1981, The American journal of cardiology.

PET measurement of adenosine stimulated absolute myocardial blood flow for physiological assessment of the coronary circulation

H. Gewirtz, 2012, Journal of Nuclear Cardiology.

Cardiac PET: a versatile, quantitative measurement tool for heart failure management.

H. Gewirtz, 2011, JACC. Cardiovascular imaging.

Coronary circulation: Pressure/flow parameters for assessment of ischemic heart disease

H. Gewirtz, 2019, Journal of Nuclear Cardiology.

Adaptation to the stress of tachycardia in patients with coronary artery disease: insight into the mechanism of the warm-up phenomenon.

H. Gewirtz, T. Bass, D. Williams, 1985, Circulation.

Mechanosensitive adenylate cyclase activity in coronary vascular smooth muscle cells.

B. Sumpio, H. Gewirtz, G. Letsou, 1990, Biochemical and biophysical research communications.

How close is close enough?

H. Gewirtz, 2014, JACC. Cardiovascular imaging.

Quantitative PET measurements of regional myocardial blood flow: observations in humans with ischemic heart disease.

N. Alpert, R. Dinsmore, A. Fischman, 1997, Cardiology.

From Physiology of the Coronary Circulation to Myocardial Perfusion Imaging

H. Gewirtz, 2015, Current Cardiovascular Imaging Reports.

Stress CMR myocardial perfusion imaging (CMR-MPI) is cost-effective compared to nuclear SPECT: a retrospective cost-effectiveness analysis

Joshua T. Cohen, R. Kwong, N. Olchanski, 2012, Journal of Cardiovascular Magnetic Resonance.

Chronic cyclic strain reduces adenylate cyclase activity and stimulatory G protein subunit levels in coronary smooth muscle cells.

B. Sumpio, H. Gewirtz, I. Mills, 1994, Experimental cell research.

PET 18F-flurpridaz quantitative measurements of myocardial blood flow: Added value for diagnosis of coronary artery disease? Of course!

H. Gewirtz, 2020, Journal of Nuclear Cardiology.

Effects of short-term treatment of hyperlipidemia on coronary vasodilator function and myocardial perfusion in regions having substantial impairment of baseline dilator reverse.

N. Alpert, A. Fischman, R. Pasternak, 1998, Circulation.

Value and limitations of myocardial thallium washout rate in the noninvasive diagnosis of patients with triple-vessel coronary artery disease.

H. Gewirtz, A. S. Most, M. Sullivan, 1983, American heart journal.

Effect of pressure-controlled intermittent coronary sinus occlusion on pacing-induced myocardial ischemia in domestic swine.

F. Fedele, H. Gewirtz, R. Capone, 1988, Circulation.

Prevalence and non-invasive predictors of left main or three-vessel coronary disease: evidence from a collaborative international meta-analysis including 22 740 patients

M. Budoff, R. Rubinshtein, F. Gaita, 2012, Heart.

Serious and potentially life threatening complications of cardiac stress testing: Physiological mechanisms and management strategies

N. Crone, V. Dilsizian, R. Schwartz, 2015, Journal of Nuclear Cardiology.

Homocysteine impairs coronary microvascular dilator function in humans.

N. Alpert, A. Fischman, J. Loscalzo, 2002, Journal of the American College of Cardiology.

Metabolic response to prolonged reduction of myocardial blood flow distal to a severe coronary artery stenosis.

F. Fedele, H. Gewirtz, R. Capone, 1988, Circulation.

Effect of intraaortic balloon counterpulsation on regional myocardial blood flow and oxygen consumption in the presence of coronary artery stenosis: observations in an awake animal model.

Ying Sun, W. Ohley, David O. Williams, 1982, The American journal of cardiology.

The Effect of Intraaortic Balloon Counterpulsation on Regional M4yocardial Blood Flow and Oxygen Consumption in the Presence of Coronary Artery Stenosis in Patients with Unstable Angina

H. Gewirtz, K. Korr, D. Williams, 1982, Circulation.

Origin of anterior interventricular vein blood in domestic swine.

H. Gewirtz, B. Sharaf, J. Bier, 1991, The American journal of physiology.

The Effect of Ischemia on Thallium-201 Clearance from the Myocardium

W. Daggett, G. Pohost, H. Strauss, 1978, Circulation.

Parametric images for quantitative measurements of regional myocardial blood flow in humans: a step in the right direction.

H. Gewirtz, 1993, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Details of coronary stenosis morphology influence its hemodynamic severity and distal flow reserve.

F. Fedele, H. Gewirtz, B. Sharaf, 1989, Circulation.

Cardiac Imaging for Coronary Heart Disease Risk Stratification in Chronic Kidney Disease.

M. Al-mallah, V. Dilsizian, T. Marwick, 2020, JACC. Cardiovascular imaging.

Exercise-induced ST-segment elevation in ECG lead aVR is a useful indicator of significant left main or ostial LAD coronary artery stenosis.

Hui Zheng, H. Gewirtz, M. Leavitt, 2011, JACC. Cardiovascular imaging.

Effect of a reduction in blood viscosity on maximal myocardial oxygen delivery distal to a moderate coronary stenosis.

H. Gewirtz, A. S. Most, N. Ruocco, 1986, Circulation.

Measurement by Electrical Impedance Aggregometry of Porcine Platelets Response to Selected Physiological Agonists 1

H. Gewirtz, M. Steiner, H. Sasken, 1985, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

High-dose folic acid acutely improves coronary vasodilator function in patients with coronary artery disease.

N. Alpert, A. Fischman, J. Muller, 2005, Journal of the American College of Cardiology.

Role of Adenosine in the Maintenance of Coronary Vasodilation Distal to a Severe Coronary Artery Stenosis

D. Brautigan, H. Gewirtz, A. S. Most, 1983, Circulation research.

Pattern of changes over time in myocardial blood flow and microvascular dilator capacity in patients with normally functioning cardiac allografts.

A. Fischman, N. Narula, S. Kushwaha, 1998, The American journal of cardiology.

Does CABG improve left ventricular ejection fraction in patients with ischemic cardiomyopathy, and does it matter?

A. Tawakol, H. Gewirtz, 2001, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Evidence of reduced resting blood flow in viable myocardial regions with chronic asynergy.

N. Alpert, A. Fischman, M. Picard, 2000, Journal of the American College of Cardiology.

Myocardial thallium-201 kinetics.

H. Gewirtz, A. S. Most, M. Sullivan, 1982, Circulation.

Thallium Redistribution in Dogs with Severe Coronary Artery Stenosis of Fixed Caliber

J. Leppo, W. Daggett, R. Okada, 1981, Circulation research.

Serial PET Measurements of Myocardial Blood Flow for Prognosis Assessment in Heart Transplant Patients: The Forest and the Trees.

H. Gewirtz, 2020, JACC. Cardiovascular imaging.

Influence of coronary vasodilation on the transmural distribution of myocardial blood flow distal to a severe fixed coronary artery stenosis.

H. Gewirtz, D. Williams, A. S. Most, 1983, American heart journal.

Evaluation of the role of coronary angioplasty in patients with unstable angina pectoris.

H. Gewirtz, D. Williams, R. S. Riley, 1981, American heart journal.

Regulating myocardial blood flow in health and disease

H. Gewirtz, 2009, Current cardiology reports.

Limitations of visual assessment of redistribution in thallium images.

H. Gewirtz, A. S. Most, M. Moore, 1984, American heart journal.

Differential myocardial washout of technetium-99m-teboroxime: mechanism and significance.

H. Gewirtz, 1991, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Myocardial imaging for mitochondrial membrane potential.

H. Gewirtz, 2012, JACC. Cardiovascular imaging.

Issues With Estimating “Diastolic Function” and Left Ventricular Filling Pressure Using the New Guidelines

F. Jaffer, R. Yeh, H. Gewirtz, 2022 .

Impaired arteriolar vasodilation induced by thrombosis of a coronary arterial stenosis.

H. Gewirtz, M. Steiner, H. Sasken, 1985, The American journal of physiology.

Utilization of stress testing for low-risk patients with chest discomfort in the emergency department

J. Wasfy, H. Gewirtz, R. Weiner, 2019, Journal of Nuclear Cardiology.

Reinnervation post-heart transplantation.

S. Kushwaha, H. Gewirtz, A. Grupper, 2017, European heart journal.

Cardiac Transplantation: Denervation, Reinnervation, and Myocardial Blood Flow

S. Kushwaha, H. Gewirtz, A. Grupper, 2017 .

Functional Versus Anatomic Imaging of CAD: Lessons Learned from Recent Clinical Trials

H. Gewirtz, 2015, Current Cardiology Reports.

Relation between coronary "steal" and contractile function at rest in collateral-dependent myocardium of humans with ischemic heart disease.

N. Alpert, A. Fischman, M. Picard, 1999, Circulation.

PET scanning in evaluation of ischemic heart disease.

H. Gewirtz, 1991, Rhode Island medical journal.

Comparison of positron emission tomography measurement of adenosine-stimulated absolute myocardial blood flow versus relative myocardial tracer content for physiological assessment of coronary artery stenosis severity and location.

A. Fischman, Hui Zheng, H. Gewirtz, 2009, JACC. Cardiovascular imaging.

Target Vessel Revascularization and Territory of Myocardial Ischemia in Patients With Chronic Total Occlusions.

F. Jaffer, R. Yeh, H. Gewirtz, 2017, Journal of the American College of Cardiology.

'Funny' current: if heart rate slowing is not the best answer, what might be?

H. Gewirtz, 2009, Cardiovascular research.

The “fixed” SPECT MPI defect: Where are we and where should we be going?

H. Gewirtz, 2020, Journal of Nuclear Cardiology.

Myocardial hibernation: unresolved physiological and clinical issues

H. Gewirtz, 1995, Basic Research in Cardiology.

Myocardial adaptation during and after sustained, demand-induced ischemia. Observations in closed-chest, domestic swine.

A. Fischman, A. Nunn, J. Southern, 1996, Circulation.

Effects of sildenafil on myocardial blood flow in humans with ischemic heart disease

N. Alpert, A. Fischman, R. Migrino, 2005, Coronary artery disease.

A phase I study evaluating dosimetry and myocardial pharmacokinetic behavior of BFPET, a new F-18 labeled tracer for myocardial perfusion imaging

S. Weise, A. Fischman, J. Correia, 2009 .

PET measurement of absolute myocardial blood flow and LV function in dilated cardiomyopathy.

H. Gewirtz, 2011, JACC. Cardiovascular imaging.

Adenosine's role in regulating basal coronary arteriolar tone.

D. Brautigan, H. Gewirtz, A. S. Most, 1986, The American journal of physiology.

Contrasting effects of nifedipine and adenosine on regional myocardial flow distribution and metabolism distal to a severe coronary arterial stenosis: observations in sedated, closed-chest, domestic swine.

H. Gewirtz, D. Williams, A. S. Most, 1984, Circulation.

The effect of transient ischemia with reperfusion on thallium clearance from the myocardium.

H. Gewirtz, A. S. Most, M. Sullivan, 1980 .

Positron-Emission Tomography Quantitative Measurements of Myocardial Blood Flow: Just the Facts….

C. Morgan, H. Schelbert, A. Iskandrian, 2019, JACC. Cardiovascular imaging.

Letter regarding article by Kaufmann et al, "systemic inhibition of nitric oxide synthase unmasks neural constraint of maximal myocardial blood flow in humans".

H. Gewirtz, 2005, Circulation.

The Effect of Intraaortic Balloon Counterpulsation

H. Gewirtz, K. Korr, 2005 .

Measurement of Plasma Adenosine Concentration: Methodological and Physiological Considerations 1

H. Gewirtz, A. S. Most, P. Brown, 1987, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Myocardial technetium-99m-teboroxime activity in acute coronary artery occlusion and reperfusion: relation to myocardial blood flow and viability.

A. Nunn, H. Strauss, H. Gewirtz, 1995, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Generation of 3-D cardiac images from magnetic resonance data

W. Ohley, H. Gewirtz, P. M. Daly, 1989, Images of the Twenty-First Century. Proceedings of the Annual International Engineering in Medicine and Biology Society,.

Quantitative PET measurements of myocardial blood flow in young, healthy volunteers what should we expect?

H. Gewirtz, 2011, JACC. Cardiovascular imaging.

Role of endogenous prostacyclin in myocardial blood flow regulation distal to a severe coronary stenosis.

H. Gewirtz, M. Steiner, H. Sasken, 1988, Cardiovascular research.

Influence of Serotonin on Myocardial Blood Flow in the Presence and Absence of a Coronary Arterial Stenosis: Observations in Domestic Swine 1

H. Gewirtz, M. Steiner, H. Sasken, 1988, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Role of adenosine in mediating the coronary vasodilative response to acute hypoxia.

H. Gewirtz, A. S. Most, R. Olsson, 1987, Cardiovascular research.

Tight software, methodological/physiological variation, less so

H. Gewirtz, 2018, Journal of Nuclear Cardiology.

Tissue acidosis: role in sustained arteriolar dilatation distal to a coronary stenosis.

F. Fedele, H. Gewirtz, B. Sharaf, 1989, Circulation.

Transient Defects of Resting Thallium Scans in Patients with Coronary Artery Disease

R. Dinsmore, G. Beller, G. Pohost, 1979, Circulation.

Use of the nasolabial flap for reconstruction of the floor of the mouth.

H. Zarem, H. Gewirtz, F. Eilber, 1978, American journal of surgery.

Observations in Conscious Domestic Swine

D. Brautigan, H. Gewirtz, A. S. Most, 2005 .

Role of pulmonary vascular resistance measurements in preoperative evaluation of candidates for pulmonary resection.

J. M. Alexander, E. Holmes, H. Gewirtz, 1978, The Journal of thoracic and cardiovascular surgery.

Importance of systematic review of rotating projection images from Tc99m-sestamibi cardiac perfusion imaging for noncardiac findings

James A Scott, Stephen E. Jones, T. Yasuda, 2008, Nuclear medicine communications.

Bilateral subclavian artery aneurysm associated with idiopathic cystic medial necrosis.

H. Gewirtz, J. H. Grollman, H. Fee, 1978, The Annals of thoracic surgery.

Impact of Myocardial Viability and Left Ventricular Lead Location on Clinical Outcome in Cardiac Resynchronization Therapy Recipients with Ischemic Cardiomyopathy

Jagmeet P. Singh, L. Mulligan, H. Gewirtz, 2014, Journal of cardiovascular electrophysiology.

Diagnosis of left-ventricular mural thrombus by means of radionuclide ventriculography.

H. Gewirtz, A. S. Most, A. Wilner, 1981, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

The Influence of Left Ventricular Volume and Wall Motion on Myocardial Images

G. Pohost, H. Strauss, H. Gewirtz, 1979, Circulation.

Clinical Quantification of Myocardial Blood Flow Using PET: Joint Position Paper of the SNMMI Cardiovascular Council and the ASNC

D. Berman, P. Slomka, A. Einstein, 2017, The Journal of Nuclear Medicine.

Clinical Quantification of Myocardial Blood Flow Using PET: Joint Position Paper of the SNMMI Cardiovascular Council and the ASNC

Venkatesh L. Murthy, Piotr J. Slomka, Daniel S. Berman, 2017, Journal of Nuclear Cardiology.

LABORATORY INVESTIGATION

F. Fedele, H. Gewirtz, R. Capone, 2005 .

Severe Coronary Artery Stenosis

F. Fedele, H. Gewirtz, R. Capone, 2005 .

Resolution of extensive left ventricular dyskinesis 3 months after acute myocardial infarction.

H. Gewirtz, E. Berger, A. S. Most, 1987, American heart journal.

Ischemia-induced impairment of left ventricular relaxation: relation to reduced diastolic filling rates of the left ventricle.

W. Ohley, H. Gewirtz, J. Walsh, 1983, American heart journal.

PET measurements of myocardial blood flow post myocardial infarction: Relationship to invasive and cardiac magnetic resonance studies and potential clinical applications

H. Gewirtz, 2017, Journal of Nuclear Cardiology.

Nuclear Cardiology and Exercise Stress Testing

H. Gewirtz, G. Upadhyay, Imad Ahmado, 2014 .

Factors influencing regional myocardial contractile response to inotropic stimulation. Analysis in humans with stable ischemic heart disease.

N. Alpert, A. Fischman, M. Picard, 1996, Circulation.

Positron emission tomographic measurements of absolute regional myocardial blood flow permits identification of nonviable myocardium in patients with chronic myocardial infarction.

N. Alpert, A. Fischman, H. Strauss, 1994, Journal of the American College of Cardiology.

Imaging perfusion deficits in ischemic heart disease with susceptibility-enhanced T2-weighted MRI: preliminary human studies.

B R Rosen, T J Brady, R M Weisskoff, 1998, Magnetic resonance imaging.

Myocardial Viability: Survival Mechanisms and Molecular Imaging Targets in Acute and Chronic Ischemia

V. Dilsizian, H. Gewirtz, 2017, Circulation research.

Integration of Quantitative Positron Emission Tomography Absolute Myocardial Blood Flow Measurements in the Clinical Management of Coronary Artery Disease

V. Dilsizian, H. Gewirtz, 2016, Circulation.

Direct comparison of rest and adenosine stress myocardial perfusion CT with rest and stress SPECT

Udo Hoffmann, Ammar Sarwar, Henry Gewirtz, 2009, Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.

Correction to: Clinical Quantification of Myocardial Blood Flow Using PET: Joint Position Paper of the SNMMI Cardiovascular Council and the ASNC

D. Berman, P. Slomka, M. Cerqueira, 2018, Journal of Nuclear Cardiology.

Henry Gewirtz and Vasken Dilsizian Flow Measurements in the Clinical Management of Coronary Artery Disease Integration of Quantitative Positron Emission Tomography Absolute Myocardial Blood

V. Dilsizian, H. Gewirtz, 2016 .

Myocardial blood flow and oxygen consumption in patients with Friedreich's ataxia prior to the onset of cardiomyopathy

Shawn A. Gregory, P. Ellinor, A. Fischman, 2006, Coronary artery disease.

ositron Emission Tomography maging Provides a Noninvasive Measure f Carotid Plaque Inflammation in Patients

R. Cury, K. Furie, T. Brady, 2006 .

Effects of dobutamine at maximally tolerated dose on myocardial blood flow in humans with ischemic heart disease.

N. Alpert, A. Fischman, M. Picard, 1997, Circulation.

Adaptive responses of coronary circulation and myocardium to chronic reduction in perfusion pressure and flow.

W. Gray, J. Fallon, H. Gewirtz, 1994, The American journal of physiology.

PET for Detection and Reporting Coronary Microvascular Dysfunction: A JACC: Cardiovascular Imaging Expert Panel Statement.

Deepak L. Bhatt, V. Dilsizian, R. Gropler, 2023, JACC. Cardiovascular imaging.

Sclerosing Cholangitis and Primary Biliary Cirrhosis—a Disease Spectrum?

W. Longmire, H. Gewirtz, H. Fee, 1977, Annals of surgery.

Role of right ventricular infarction in cardiogenic shock associated with inferior myocardial infarction.

H. Gold, J. Fallon, R. Pasternak, 1979, British heart journal.

4-[18F]-tetraphenylphosphonium as a PET tracer for myocardial mitochondrial membrane potential.

S. Weise, H. Gewirtz, T. Shoup, 2012, JACC. Cardiovascular imaging.

Coronary Stenosis

F. Fedele, H. Gewirtz, B. Sharaf, 2005 .

Cardiac PET-CT for Monitoring Medical and Interventional Therapy in Patients with CAD: PET Alone Versus Hybrid PET-CT?

H. Gewirtz, Q. Truong, 2014, Current Cardiology Reports.

CMR quantitative measurements of myocardial blood flow: Not ready for routine clinical application

H. Gewirtz, 2019, Journal of Nuclear Cardiology.

The effect of generalized alpha-receptor stimulation on regional myocardial blood flow distal to a severe coronary artery stenosis.

H. Gewirtz, D. Williams, A. S. Most, 1982, Circulation.

Role of myocardial ischemia in the genesis of stress-induced S-T segment elevation in previous anterior myocardial infarction.

H. Gewirtz, A. S. Most, M. Sullivan, 1983, The American journal of cardiology.

Heterogeneity of myocardial blood flow and metabolism: Review of physiologic principles and implications for radionuclide imaging of the heart

A. Tawakol, H. Gewirtz, Stephen L. Bacharach, 2002, Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.

Cultured vascular smooth muscle cells from porcine coronary artery possess A1 and A2 adenosine receptor activity.

H. Gewirtz, I. Mills, 1990, Biochemical and Biophysical Research Communications - BBRC.

Myocardial flow regulation in people with mitochondrial myopathy, encephalopathy, lactic acidosis, stroke‐like episodes/myoclonic epilepsy and ragged red fibers and other mitochondrial syndromes

N. Alpert, A. Fischman, J. Friedman, 2003, Coronary artery disease.

Delayed heart rate recovery after adenosine stress testing with supplemental arm exercise predicts mortality

Shawn A. Gregory, G. Thomas, Y. Akutsu, 2009, Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.

Fractional flow reserve.

H. Gewirtz, 1996, Circulation.

Coronary circulation: Pressure/flow parameters for assessment of ischemic heart disease.

H. Gewirtz, 2019, Journal of Nuclear Cardiology.

SPECT Myocardial Perfusion Imaging: Poststress, End Systolic Images and the Ongoing Effort to Improve Diagnostic Accuracy

H. Gewirtz, 2015, The Journal of Nuclear Medicine.