Wei Li

Duane D. Miller, Wei Li, A. Slominski, 2008, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

Enzymatic metabolism of ergosterol by cytochrome p450scc to biologically active 17alpha,24-dihydroxyergosterol.

Wei Li, A. Slominski, J. Wortsman, 2005, Chemistry & biology.

Discovery of a Highly Selective and Potent TRPC3 Inhibitor with High Metabolic Stability and Low Toxicity.

Duane D. Miller, Wei Li, F. Liao, 2021, ACS medicinal chemistry letters.

Design, synthesis and biological evaluation of selective survivin inhibitors

Zhe-Sheng Chen, Jin Wang, Wei Li, 2019, Journal of biomedical research.

Recent Advances on Small-Molecule Survivin Inhibitors

Wei Li, Min Xiao, 2015, Current medicinal chemistry.

A new steroidal 5,7-diene derivative, 3β-hydroxyandrosta-5,7-diene-17β-carboxylic acid, shows potent anti-proliferative activity

Duane D. Miller, Wei Li, A. Slominski, 2010, Steroids.

Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells

Wei Li, A. Slominski, K. Kleszczyński, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

pH-sensitive nanomedicine of novel tubulin polymerization inhibitor to lung metastatic melanoma.

R. Bhattarai, R. Mahato, Virender Kumar, 2022, Journal of controlled release : official journal of the Controlled Release Society.

Modulation by 17,20S(OH)2pD of Fibrosis-Related Mediators in Dermal Fibroblast Lines from Healthy Donors and from Patients with Systemic Sclerosis

Duane D. Miller, Wei Li, A. Slominski, 2021, International journal of molecular sciences.

The Roles of Vitamin D and Its Analogs in Inflammatory Diseases.

Wei Li, Zongtao Lin, 2016, Current topics in medicinal chemistry.

Medetomidine analogs as selective agonists for the human alpha2-adrenoceptors.

Duane D. Miller, S. Liggett, Wei Li, 2004, Biochemical pharmacology.

Nanoparticulate delivery of potent microtubule inhibitor for metastatic melanoma treatment.

R. Bhattarai, R. Mahato, Virender Kumar, 2019, Journal of controlled release : official journal of the Controlled Release Society.

Structure Activity Relationships Study of Novel 6 Aryl-2-Benzoyl-Pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties.

Duane D. Miller, S. White, G. Kumar, 2019, Journal of medicinal chemistry.

Discovery of novel 2-aryl-4-benzoyl-imidazoles targeting the colchicines binding site in tubulin as potential anticancer agents.

Duane D. Miller, B. Meibohm, J. Dalton, 2010, Journal of medicinal chemistry.

New substituted 4H-chromenes as anticancer agents.

Duane D. Miller, Jin Wang, Wei Li, 2012, Bioorganic & medicinal chemistry letters.

Design, Synthesis and Biological Evaluation of Novel 5H-Chromenopyridines as Potential Anti-Cancer Agents

Duane D. Miller, L. Pfeffer, S. Pfeffer, 2015, Molecules.

Cesium fluoride and tetra-n-butylammonium fluoride mediated 1,4-N-->O shift of disubstituted phenyl ring of a bicalutamide derivative.

Duane D. Miller, D. Cremer, E. Kraka, 2006, Tetrahedron letters.

Current advances of tubulin inhibitors as dual acting small molecules for cancer therapy

Souvik Banerjee, Duane D. Miller, Hao Chen, 2019, Medicinal research reviews.

A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance.

Duane D. Miller, F. Park, J. Dalton, 2018, Cancer research.

Synthesis, biological evaluation, and structural studies on N1 and C5 substituted cycloalkyl analogues of the pyrazole class of CB1 and CB2 ligands.

Wei Li, M. Krishnamurthy, B. Moore, 2004, Bioorganic & medicinal chemistry.

An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site

Yan Lu, Duane D. Miller, Wei Li, 2012, Pharmaceutical Research.

Structure determination of chiral sulfoxide in diastereomeric bicalutamide derivatives.

Elfi Kraka, Dieter Cremer, Duane D. Miller, 2009, Chirality.

Synthesis and evaluation of new 1,2,3,4-tetrahydroisoquinoline analogs as antiglioma agents

Duane D. Miller, W. E. Orr, E. Geisert, 2010, Medicinal Chemistry Research.

Calcium‐ and Voltage‐Gated Potassium (BK) Channel Activators in the 5β‐Cholanic Acid‐3α‐ol Analogue Series with Modifications in the Lateral Chain

Duane D. Miller, Wei Li, A. Dopico, 2012, ChemMedChem.

Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy.

Duane D. Miller, S. White, G. Kumar, 2018, Journal of medicinal chemistry.

In Silico Screening and In Vivo Evaluation of Potential CACNA2D1 Antagonists as Intraocular Pressure-Reducing Agents in Glaucoma Therapy

Wei Li, Hao Chen, M. Jablonski, 2021, Pharmaceuticals.

Ultra-performance LC separation and quadrupole time-of-flight MS identification of major alkaloids in Plumula Nelumbinis.

Wei Li, Ailiang Chen, Ruinan Yang, 2014, Phytochemical analysis : PCA.

Synthesis and antiproliferative activity of thiazolidine analogs for melanoma.

Duane D. Miller, J. Dalton, Yan Lu, 2007, Bioorganic & medicinal chemistry letters.

Discovery of 4-Aryl-2-benzoyl-imidazoles as tubulin polymerization inhibitor with potent antiproliferative properties.

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2013, Journal of medicinal chemistry.

N1-Acetyl-5-Methoxykynuramine (AMK) is produced in the human epidermis and shows antiproliferative effects.

R. Reiter, Wei Li, A. Slominski, 2015, Endocrinology.

An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site

Duane D. Miller, Yan Lu, Wei Li, 2012, Pharmaceutical Research.

Structure-activity relationship studies of arylthiazolidine amides as selective cytotoxic agents for melanoma.

Duane D. Miller, J. Dalton, Wei Li, 2007, Anticancer research.

Novel Tubulin Polymerization Inhibitors Overcome Multidrug Resistance and Reduce Melanoma Lung Metastasis

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2012, Pharmaceutical Research.

HIF-1α pathway: role, regulation and intervention for cancer therapy

Wei Li, Georgina N. Masoud, 2015, Acta pharmaceutica Sinica. B.

Synthesis and biological evaluation of indole-based UC-112 analogs as potent and selective survivin inhibitors.

Duane D. Miller, Zhe-Sheng Chen, Wei Li, 2018, European journal of medicinal chemistry.

Ribozyme Ablation Demonstrates That the Cardiac Subtype of the Voltage-sensitive Calcium Channel Is the Molecular Transducer of 1,25-Dihydroxyvitamin D3-stimulated Calcium Influx in Osteoblastic Cells*

Wei Li, J. Bergh, N. Karin, 2000, The Journal of Biological Chemistry.

Recent Progress on Tubulin Inhibitors with Dual Targeting Capabilities for Cancer Therapy.

Duane D. Miller, L. Ouyang, Guan Wang, 2021, Journal of medicinal chemistry.

Survivin Small Molecules Inhibitors: Recent Advances and Challenges

Wei Li, Najah Albadari, 2023, Molecules.

Structural Optimization of Indole Derivatives Acting at Colchicine Binding Site as Potential Anticancer Agents.

Duane D. Miller, Jin Wang, Wei Li, 2015, ACS medicinal chemistry letters.

Design, Synthesis and Structure-Activity Relationship Studies of Novel Survivin Inhibitors with Potent Anti-Proliferative Properties

Duane D. Miller, Jin Wang, S. White, 2015, PloS one.

Discovery of Novel Second Mitochondria-Derived Activator of Caspase Mimetics as Selective Inhibitor of Apoptosis Protein Inhibitors

Jin Wang, Wei Li, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Synergistic Combination of Novel Tubulin Inhibitor ABI-274 and Vemurafenib Overcomes Vemurafenib Acquired Resistance in BRAFV600E Melanoma

Duane D. Miller, Jin Wang, Wei Li, 2013, Molecular Cancer Therapeutics.

Recent Advances in Heterocyclic Tubulin Inhibitors Targeting the Colchicine Binding Site.

Wei Li, Qinghui Wang, Xiaoxin Wu, 2016, Anti-cancer agents in medicinal chemistry.

Synthesis and biological evaluation of selective survivin inhibitors derived from the MX-106 hydroxyquinoline scaffold.

Duane D. Miller, Guannan Zhao, J. Yue, 2021, European journal of medicinal chemistry.

Knockdown of survivin results in inhibition of epithelial to mesenchymal transition in retinal pigment epithelial cells by attenuating the TGFβ pathway.

Peng Zhang, E. Chaum, Guannan Zhao, 2018, Biochemical and biophysical research communications.

Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors

Wei Li, Santosh Kumar, Narasimha M. Midde, 2017, Pharmacology research & perspectives.

Non-Musculoskeletal Benefits of Vitamin D beyond the Musculoskeletal System

Duane D. Miller, Wei Li, Sicheng Zhang, 2021, International journal of molecular sciences.

Cytochromes p450 and skin cancer: role of local endocrine pathways.

Wei Li, A. Slominski, M. Żmijewski, 2014, Anti-cancer agents in medicinal chemistry.

Novel non-calcemic secosteroids that are produced by human epidermal keratinocytes protect against solar radiation

Wei Li, R. Sayre, J. Dowdy, 2015, The Journal of Steroid Biochemistry and Molecular Biology.

VERU-111 suppresses tumor growth and metastatic phenotypes of cervical cancer cells through the activation of p53 signaling pathway.

Duane D. Miller, N. Chauhan, M. Jaggi, 2019, Cancer letters.

The transcriptional factors HIF-1 and HIF-2 and their novel inhibitors in cancer therapy

Wei Li, Shanshan Deng, Najah Albadari, 2019, Expert opinion on drug discovery.

Ovarian Primary and Metastatic Tumors Suppressed by Survivin Knockout or a Novel Survivin Inhibitor

P. Dong, H. Watari, L. Pfeffer, 2019, Molecular Cancer Therapeutics.

An Orally Available Tubulin Inhibitor, VERU-111, Suppresses Triple-Negative Breast Cancer Tumor Growth and Metastasis and Bypasses Taxane Resistance

Duane D. Miller, Wei Li, Qinghui Wang, 2019, Molecular Cancer Therapeutics.

Multidimensional HRMAS NMR: a platform for in vivo studies using intact bacterial cells.

Wei Li, 2006, The Analyst.

Colchicine Binding Site Agent DJ95 Overcomes Drug Resistance and Exhibits Antitumor Efficacy

Duane D. Miller, Zhe-Sheng Chen, S. White, 2019, Molecular Pharmacology.

Synthesis and antiproliferative activity of novel 2-aryl-4-benzoyl-imidazole derivatives targeting tubulin polymerization.

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2011, Bioorganic & medicinal chemistry.

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–6

F. J. Luque, R. Capasso, C. Hulme, 2019, Molecules.

Polymer conjugate of a microtubule destabilizer inhibits lung metastatic melanoma

Duane D. Miller, R. Mahato, Wei Li, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Therapeutic Agents for Advanced Melanoma

Duane D. Miller, Wei Li, Zhao Wang, 2013 .

Nanoformulation design and therapeutic potential of a novel tubulin inhibitor in pancreatic cancer.

V. Bhatt, R. Bhattarai, R. Mahato, 2020, Journal of controlled release : official journal of the Controlled Release Society.

Polymeric Micellar Delivery of Novel Microtubule Destabilizer and Hedgehog Signaling Inhibitor for Treating Chemoresistant Prostate Cancer

Duane D. Miller, R. Mahato, Wei Li, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Hydroxylation of CYP11A1-Derived Products of Vitamin D3 Metabolism by Human and Mouse CYP27B1

Wei Li, A. Slominski, R. Tuckey, 2013, Drug Metabolism and Disposition.

DMD050955 1112..1124

Wei Li, A. Slominski, R. Tuckey, 2013 .

Hydroxylation of CYP 11 A 1-Derived Products of Vitamin D 3 Metabolism by Human and Mouse CYP 27 B 1

Wei Li, A. Slominski, R. Tuckey, 2013 .

Emerging Drug Combination Approaches in Melanoma Therapy

Duane D. Miller, Jin Wang, Wei Li, 2015 .

20S-Hydroxyvitamin D3, a Secosteroid Produced in Humans, Is Anti-Inflammatory and Inhibits Murine Autoimmune Arthritis

Wei Li, A. Slominski, R. Tuckey, 2021, Frontiers in Immunology.

Chemical synthesis of 20S-hydroxyvitamin D3, which shows antiproliferative activity

Duane D. Miller, Yan Lu, Wei Li, 2010, Steroids.

Berberine, A Phytoalkaloid, Inhibits Inflammatory Response Induced by LPS through NF-Kappaβ Pathway: Possible Involvement of the IKKα

Wei Li, K. Reddi, S. Tetali, 2021, Molecules.

Chapter 8 Emerging Drug Combination Approaches in Melanoma Therapy

Duane D. Miller, Jin Wang, Wei Li, 2018 .

Inhibition of TRPC3 channels by a novel pyrazole compound confers antiseizure effects

Wei Li, Jianxiong Jiang, Zhongzhi Wu, 2022, Epilepsia.

Systemic delivery of nanoparticle formulation of novel tubulin inhibitor for treating metastatic melanoma

Duane D. Miller, R. Mahato, Wei Li, 2015, Drug Delivery and Translational Research.

Synthesis and antiproliferative activity of imidazole and imidazoline analogs for melanoma.

Duane D. Miller, J. Dalton, Yan Lu, 2008, Bioorganic & medicinal chemistry letters.

Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid.

Duane D. Miller, G. Mills, M. Gotoh, 2010, Bioorganic & medicinal chemistry letters.

Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo.

Duane D. Miller, Rui Wang, Wei Li, 2023, ACS pharmacology & translational science.

X-ray Crystallography-Guided Design, Antitumor Efficacy, and QSAR Analysis of Metabolically Stable Cyclopenta-Pyrimidinyl Dihydroquinoxalinone as a Potent Tubulin Polymerization Inhibitor.

Duane D. Miller, B. Meibohm, S. White, 2021, Journal of medicinal chemistry.

X-Ray Crystal Structure Guided Discovery and Antitumor Efficacy of Dihydroquinoxalinone as Potent Tubulin Polymerization Inhibitors.

Duane D. Miller, Wei Li, Weimin Li, 2019, ACS chemical biology.

Synthesis and testing of novel classical cannabinoids: exploring the side chain ligand binding pocket of the CB1 and CB2 receptors.

Wei Li, M. Krishnamurthy, B. Moore, 2003, Bioorganic & medicinal chemistry.

Glyconanoparticle aided detection of β-amyloid by magnetic resonance imaging and attenuation of β-amyloid induced cytotoxicity.

David C. Zhu, Wei Li, Xuefei Huang, 2013, ACS chemical neuroscience.

Recent Advances in Elucidating Paclitaxel Resistance Mechanisms in Non-small Cell Lung Cancer and Strategies to Overcome Drug Resistance.

Duane D. Miller, Wei Li, K. Arnst, 2020, Current medicinal chemistry.

RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20‐hydroxy‐ and 20,23‐dihydroxyvitamin D

Jin Wang, Y. Takeda, A. Jetten, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions

Wei Li, A. Slominski, A. Yi, 2014, The Journal of Steroid Biochemistry and Molecular Biology.

Methods for acquisition and assignment of multidimensional high-resolution magic angle spinning NMR of whole cell bacteria.

Wei Li, Richard E. Lee, Robin E. B. Lee, 2005, Analytical chemistry.

Taxane resistance in castration-resistant prostate cancer: mechanisms and therapeutic strategies

Wei Li, Brandon Bumbaca, 2018, Acta pharmaceutica Sinica. B.

Discovery of antiglioma activity of biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues.

Duane D. Miller, E. Geisert, Wei Li, 2006, Journal of medicinal chemistry.

Abstract 1320: Effects of selective androgen-receptor and estrogen-receptor modulators on telomerase activity in melanoma and prostate cancer cells.

Duane D. Miller, Jin Wang, Yan Lu, 2013 .

Synthesis, in vitro structure-activity relationship, and in vivo studies of 2-arylthiazolidine-4-carboxylic acid amides as anticancer agents.

Duane D. Miller, J. Dalton, Yan Lu, 2010, Bioorganic & medicinal chemistry.

Discovery of N-(3,4-Dimethylphenyl)-4-(4-isobutyrylphenyl)-2,3,3a,4,5,9b-hexahydrofuro[3,2-c]quinoline-8-sulfonamide as a Potent Dual MDM2/XIAP Inhibitor.

B. Meibohm, L. Gu, Mu-xiang Zhou, 2021, Journal of medicinal chemistry.

A Luminacin D Analog HL142 Inhibits Ovarian Tumor Growth and Metastasis by Reversing EMT and Attenuating the TGFβ and FAK Pathways

P. Dong, H. Watari, Guannan Zhao, 2021, Journal of Cancer.

Therapeutic efficacy of a novel βIII/βIV-tubulin inhibitor (VERU-111) in pancreatic cancer

Duane D. Miller, N. Chauhan, M. Jaggi, 2019, Journal of experimental & clinical cancer research : CR.

The Effect of Arvanil on Prostate Cancer Cells Studied by Whole Cell High Resolution Magic Angle Spinning NMR

Wei Li, B. Moore, 2014 .

Orally Bioavailable Tubulin Antagonists for Paclitaxel-Refractory Cancer

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2012, Pharmaceutical Research.

Erratum: An alternative pathway of vitamin D2 metabolism. Cytochrome P450scc (CYP11A1)-mediated conversion to 20-hydroxyvitamin D 2 and 17,20-dihydroxyvitamin D2 (FEBS Journal (2006) 273 (2891-2901))

Wei Li, A. Slominski, J. Wortsman, 2006 .

1α,20S-Dihydroxyvitamin D3 Interacts with Vitamin D Receptor: Crystal Structure and Route of Chemical Synthesis

Duane D. Miller, N. Rochel, Wei Li, 2017, Scientific Reports.

Novel Tubulin Polymerization Inhibitors Overcome Multidrug Resistance and Reduce Melanoma Lung Metastasis

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2012, Pharmaceutical Research.

Benzimidazole analogs as potent hypoxia inducible factor inhibitors: synthesis, biological evaluation, and profiling drug-like properties.

Duane D. Miller, Jin Wang, L. Jennings, 2014, Anticancer research.

Design, Synthesis, and Biological Evaluation of Apcin-Based CDC20 Inhibitors.

F. Park, Wei Li, R. Bhuniya, 2022, ACS medicinal chemistry letters.

Structure guided design, synthesis, and biological evaluation of 2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) analogs targeting the colchicine binding site in tubulin.

Duane D. Miller, S. White, Wei Li, 2019, Journal of medicinal chemistry.

Investigation of 20S-hydroxyvitamin D3 analogs and their 1α-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities

Duane D. Miller, N. Rochel, Wei Li, 2018, Scientific Reports.

Medetomidine analogs as selective agonists for the human α2-adrenoceptors

Duane D. Miller, S. Liggett, Wei Li, 2004 .

Steroidogenesis in the skin: Implications for local immune functions

C. Zouboulis, P. Manna, Wei Li, 2013, Journal of Steroid Biochemistry and Molecular Biology.

Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytes.

Wei Li, A. Slominski, C. R. Yates, 2012, The international journal of biochemistry & cell biology.

Classical and non‐classical metabolic transformation of vitamin D in dermal fibroblasts

Wei Li, A. Slominski, R. Tuckey, 2016, Experimental dermatology.

Chemical synthesis of 20S-hydroxyvitamin D3, which shows antiproliferative activity

Duane D. Miller, Yan Lu, Wei Li, 2010, Steroids.

Colchicine-binding site agent CH-2-77 as a potent tubulin inhibitor suppressing triple-negative breast cancer.

Duane D. Miller, Hao Chen, B. Meibohm, 2022, Molecular cancer therapeutics.

Structure elucidation of major metabolites from medroxyprogesterone acetate by P450.

Wei Li, Ling Yang, Jianjun Chen, 2009, Chemical & pharmaceutical bulletin.

Endogenously produced nonclassical vitamin D hydroxy-metabolites act as “biased” agonists on VDR and inverse agonists on RORα and RORγ

A. Jetten, Wei Li, A. Slominski, 2017, The Journal of Steroid Biochemistry and Molecular Biology.

Discovery of Novel Second Mitochondria-Derived Activator of Caspase Mimetics as Selective Inhibitor of Apoptosis Protein Inhibitors

Jin Wang, Wei Li, 2014, The Journal of Pharmacology and Experimental Therapeutics.