N. Le

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Radiotracers for low density lipoprotein biodistribution studies in vivo: technetium-99m low density lipoprotein versus radioiodinated low density lipoprotein preparations.

V. Fuster, S. Vallabhajosula, J. Badimón, 1988, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Suppression of apolipoprotein B production during treatment of cholesteryl ester storage disease with lovastatin. Implications for regulation of apolipoprotein B synthesis.

R. Desnick, M. Short, H. Ginsberg, 1987, The Journal of clinical investigation.

Individual variation in macronutrient regulation measured by proton magnetic resonance spectroscopy of human plasma.

Dean P. Jones, R. Alexander, T. Ziegler, 2009, American journal of physiology. Regulatory, integrative and comparative physiology.

Effect of changing dietary fat saturation on low-density lipoprotein metabolism in man.

N. Le, W. Brown, J. Turner, 1981, The American journal of physiology.

Determinants of fasting plasma triglyceride levels: metabolism of hepatic and intestinal lipoproteins

J. Cortner, M. Bennett, N. Le, 1992, European journal of clinical investigation.

Glial cell line-derived neurotrophic factor protects against high-fat diet-induced obesity.

F. Anania, S. Srinivasan, M. Anitha, 2014, American journal of physiology. Gastrointestinal and liver physiology.

Protein and gene markers of metabolic dysfunction and inflammation together associate with functional connectivity in reward and motor circuits in depression

Zhihao Li, D. Goldsmith, N. Le, 2020, Brain, Behavior, and Immunity.

Polyunsaturated fatty acids acutely suppress antibodies to malondialdehyde-modified lipoproteins in patients with vascular disease.

W. Q. Gradek, N. Le, W. Brown, 2004, The American journal of cardiology.

Ultrastructural changes in Bruch's membrane of apolipoprotein E-deficient mice.

C. Curcio, H. Grossniklaus, N. Le, 2000, Investigative ophthalmology & visual science.

Direct measurement of apoprotein B specific activity in 125I-labeled lipoproteins.

N. Le, W. Brown, H. Ginsberg, 1978, Journal of lipid research.

Changes in Lipoprotein Particle Number With Ezetimibe/Simvastatin Coadministered With Extended‐Release Niacin in Hyperlipidemic Patients

P. Wilson, J. Tomassini, N. Le, 2013, Journal of the American Heart Association.

Juvenile neuronal ceroid-lipofuscinosis: Characterization of the dyslipoproteinaemia and demonstration of membrane phospholipid and phospholipid-dependent signal transduction abnormalities in cultured skin fibroblasts

M. Bennett, S. Majumdar, N. Le, 1993, Journal of Inherited Metabolic Disease.

Lipid and apolipoprotein levels and distribution in patients with hypertriglyceridemia: effect of triglyceride reductions with atorvastatin.

N. Le, Xiujun Li, W. Brown, 2000, Metabolism: clinical and experimental.

An efficient chromatographic system for lipoprotein fractionation using whole plasma.

N. Le, W. Brown, W. Innis-Whitehouse, 1998, Journal of lipid research.

Effect of acute intravenous alcohol on plasma lipoproteins in man.

N. Le, W. Brown, E. Mezey, 1991, Metabolism: clinical and experimental.

Heterogeneity of apolipoprotein A-I turnover in subjects with reduced concentrations of plasma high density lipoprotein cholesterol.

N. Le, H. Ginsberg, 1988, Metabolism: clinical and experimental.

Independent regulation of plasma apolipoprotein C-II and C-III concentrations in very low density and high density lipoproteins: implications for the regulation of the catabolism of these lipoproteins.

N. Le, J. Gibson, H. Ginsberg, 1988, Journal of lipid research.

Abnormalities in lipoprotein metabolism in Gaucher type 1 disease.

H. Ginsberg, N. Le, G. Grabowski, 1988, Metabolism: clinical and experimental.

Altered high density lipoprotein metabolism in patients with myeloproliferative disorders and hypocholesterolemia.

H. Ginsberg, N. Le, H. Gilbert, 1986, Metabolism: clinical and experimental.

Direct determination of apolipoprotein C-III specific activity using immunoaffinity chromatography.

N. Le, W. Brown, J. Gibson, 1986, Methods in enzymology.

Immunoaffinity isolation of apolipoprotein E-containing lipoproteins.

I. Goldberg, N. Le, W. Brown, 1985, Biochimica et biophysica acta.

Apo E-mediated uptake and degradation of normal very low density lipoproteins by human monocyte/macrophages: a saturable pathway distinct from the LDL receptor.

N. Le, W. Brown, L. Peteanu, 1985, Biochemical and biophysical research communications.

Evidence for non-equilibrating pools of apolipoprotein C-III in plasma lipoproteins.

N. Le, W. Brown, A. Rubinstein, 1985, Journal of lipid research.

Regulation of the production and catabolism of plasma low density lipoproteins in hypertriglyceridemic subjects. Effect of weight loss.

N. Le, J. Gibson, H. Ginsberg, 1985, The Journal of clinical investigation.

Binding affinity and particle size of LDL in subjects with moderate hypercholesterolemia: relationship with in vivo LDL metabolism.

B. Howard, M. Paidi, N. Le, 1996, Journal of lipid research.

Changes in plasma lipids and lipoproteins during isotretinoin therapy for acne.

N. Le, W. Brown, A. Rubinstein, 1985, New England Journal of Medicine.

Lipoprotein metabolism in nonresponders to increased dietary cholesterol.

N. Le, W. Brown, J. Gibson, 1981, Arteriosclerosis.

Apolipoprotein C-III protein concentrations and gene polymorphisms in type 1 diabetes: associations with lipoprotein subclasses.

A. Jenkins, T. Lyons, S. Hunter, 2004, Metabolism: clinical and experimental.

Lipoprotein-Associated Oxidative Stress: A New Twist to the Postprandial Hypothesis

N. Le, 2014, International journal of molecular sciences.

How do we find the best biomarkers for cardiovascular disease?

P. Wilson, N. Le, 2010, Clinical chemistry.

Association of Early-Onset Alzheimer Disease With Elevated Low-density Lipoprotein Cholesterol Levels and Rare Genetic Coding Variants of APOB.

B. Miller, A. Wingo, D. Cutler, 2019, JAMA neurology.

Association between plasminogen activator inhibitor‐1 and severity of liver injury and cardiovascular risk in children with non‐alcoholic fatty liver disease

A. Krasinskas, N. Le, M. Vos, 2018, Pediatric obesity.

Leptin partially mediates the association between early-life nutritional supplementation and long-term glycemic status among women in a Guatemalan longitudinal cohort.

R. Martorell, K. Narayan, A. Stein, 2020, The American journal of clinical nutrition.

Long-term effect of reduced carbohydrate or increased fiber intake on LDL particle size and HDL composition in subjects with type 2 diabetes

T. Wolever, M. McBurney, N. Le, 2003 .

Small, dense low-density lipoprotein: Risk or myth?

N. Le, 2003, Current atherosclerosis reports.

Dissociation of apoprotein B and triglyceride production in very-low-density lipoproteins.

D. Steinberg, N. Le, W. Brown, 1980, The American journal of physiology.

Cardiovascular Complications in CKD Patients: Role of Oxidative Stress

E. Gosmanova, N. Le, Elvira O. Gosmanova, 2011, Cardiology research and practice.

A sulfur amino acid-free meal increases plasma lipids in humans.

Dean P. Jones, Frederick H. Strobel, Tianwei Yu, 2011, The Journal of nutrition.

The role of hypertriglyceridemia in atherosclerosis

N. Le, M. Walter, 2007, Current atherosclerosis reports.

Lipoprotein-Associated Oxidative Stress

N. Le, 2016 .

Oxidized lipids and lipoproteins: indices of risk or targets for management

N. Le, 2009 .

Increased Catabolism of Native and Cyclohexanedione‐Modified Low Density Lipoprotein in Subjects with Myeloproliferative Diseases

I. Goldberg, H. Ginsberg, N. Le, 1983, Arteriosclerosis.

Increased low-density-lipoprotein catabolism in myeloproliferative disorders.

N. Le, W. Brown, H. Gilbert, 1982, Annals of internal medicine.

Cardiometabolic risks vary by weight status in pediatric kidney and liver transplant recipients: A cross‐sectional, single‐center study in the USA

N. Le, P. Winterberg, M. Vos, 2017, Pediatric transplantation.

Postprandial Triglycerides, Oxidative Stress, and Inflammation

N. Le, 2020, Apolipoproteins, Triglycerides and Cholesterol.

Children with NAFLD are more sensitive to the adverse metabolic effects of fructose beverages than children without NAFLD.

Dean P. Jones, C. McClain, T. Ziegler, 2012, The Journal of clinical endocrinology and metabolism.

Effect of somatostatin-induced suppression of postprandial insulin response upon the hypertriglyceridemia associated with a high carbohydrate diet.

N. Le, H. Ginsberg, J. Sandler, 1982, The Journal of clinical investigation.

Plasminogen Activator Inhibitor-1 Predicts Quantity of Hepatic Steatosis Independent of Insulin Resistance and Body Weight

C. McClain, G. Arteel, T. Ziegler, 2016, Journal of pediatric gastroenterology and nutrition.

Lipoprotein metabolism during acute inhibition of hepatic triglyceride lipase in the cynomolgus monkey.

I. Goldberg, H. Ginsberg, N. Le, 1982, The Journal of clinical investigation.

Intrinsic enzymes of high-density lipoprotein.

N. Le, M. Walter, 2007, Journal of clinical lipidology.

Low-density lipoprotein particle size, central obesity, cardiovascular fitness, and insulin resistance syndrome markers in obese youths

M. Litaker, B. Gutin, N. Le, 2002, International Journal of Obesity.

Antiretroviral Therapy in HIV-Positive Women Is Associated With Increased Apolipoproteins and Total Cholesterol

C. del Rio, J. Guest, D. Rimland, 2006, Journal of acquired immune deficiency syndromes.

Visceral adipose tissue and markers of the insulin resistance syndrome in obese black and white teenagers.

M. Litaker, B. Gutin, N. Le, 2000, Obesity research.

Reducing oxidized lipids to prevent cardiovascular disease

N. Le, 2008, Current treatment options in cardiovascular medicine.

Hyperlipidemia and cardiovascular disease.

N. Le, 2006, Current opinion in lipidology.

Relationship between risk factor control and vascular events in the SAMMPRIS trial

A. Nizam, T. Turan, B. Egan, 2017, Neurology.

Substitution of standard soybean oil with olive oil-based lipid emulsion in parenteral nutrition: comparison of vascular, metabolic, and inflammatory effects.

Dean P. Jones, A. Quyyumi, A. Gosmanov, 2011, The Journal of clinical endocrinology and metabolism.

Apolipoprotein C-III displacement of apolipoprotein E from VLDL: effect of particle size.

N. Le, Xiujun Li, W. Brown, 1999, Journal of lipid research.

Meal-Induced Oxidative Stress

N. Le, 2016 .

Chenodeoxycholic acid normalizes elevated lipoprotein secretion and catabolism in cerebrotendinous xanthomatosis.

N. Le, G. Tint, S. Shefer, 1989, Journal of lipid research.

Protocol for efficient plasma sampling for low density lipoprotein turnover studies.

N. Le, W. Brown, H. Ginsberg, 1984, Journal of lipid research.

Direct measurement of apoprotein C-III specific activity in 125I-labeled very low density lipoproteins using immunoaffinity chromatography.

N. Le, W. Brown, J. Gibson, 1983, Journal of lipid research.

Effect of a high carbohydrate diet on apoprotein-B catabolism in man.

D. Steinberg, N. Le, W. Brown, 1981, Metabolism: clinical and experimental.

Kinetic analysis using specific radioactivity data.

R. Ramakrishnan, R. Dell, N. Le, 1986, Methods in enzymology.

Metabolism of apoprotein B in cynomolgus monkey: evidence for independent production of low-density lipoprotein apoprotein B.

I. Goldberg, N. Le, W. Brown, 1983, The American journal of physiology.

Abnormal activation of lipoprotein lipase by non-equilibrating apoC-II: further evidence for the presence of non-equilibrating pools of apolipoproteins C-II and C-III in plasma lipoproteins.

I. Goldberg, N. Le, Xiujun Li, 1993, Journal of lipid research.

Antiretroviral therapy in HIV‐positive men is associated with increased apolipoprotein CIII in triglyceride‐rich lipoproteins

C. del Rio, J. Guest, D. Rimland, 2005, HIV medicine.

Protocol for the preparation of a segmental linear polyacrylamide gradient gel: simultaneous determination of Lp[a], LDL, and HDL particle sizes.

N. Le, W. Brown, W. Innis-Whitehouse, 1997, Journal of lipid research.

Evaluation of a novel colorimetric assay for free oxygen radicals as marker of oxidative stress.

N. Le, W. Brown, M. Garelnabi, 2008, Clinical biochemistry.

Marked overproduction of low density lipoprotein apolipoprotein B in a subject with heterozygous familial hypercholesterolemia. Effect of portacaval shunting.

N. Davidson, N. Le, W. Brown, 1982, Biochimica et biophysica acta.

Amount of hepatic fat predicts cardiovascular risk independent of insulin resistance among Hispanic-American adolescents

N. Le, M. Vos, J. Otvos, 2015, Lipids in Health and Disease.

Normalization of Lipoprotein Composition by Intraperitoneal Insulin in IDDM: Role of increased hepatic lipase activity

M. Taskinen, G. Pozza, N. Le, 1994, Diabetes Care.

Hyperlipidaemia and cardiovascular disease: oxidative damage and atherosclerosis.

N. Le, 2006, Current opinion in lipidology.

Protocol for the study of the metabolism of retinyl esters in plasma lipoproteins during postprandial lipemia.

N. Le, G. Ruotolo, H. Zhang, 1992, Journal of lipid research.

Kinetics of retinyl esters during postprandial lipemia in man: a compartmental model.

J. Cortner, P. Gallagher, N. Le, 1997, Metabolism: clinical and experimental.

Postprandial Clearance of Oxidized Low-Density Lipoprotein in Patients with Stroke Due to Atherosclerosis.

T. Turan, N. Le, Renee' H. Martin, 2017, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

Inflammation, oxidative stress, and atherosclerosis.

N. Le, 2004, Current opinion in lipidology.

Editorial comment Inflammation, oxidative stress, and atherosclerosis

N. Le, 2004 .

Lipoprotein metabolism during acute inhibition of lipoprotein lipase in the cynomolgus monkey.

R. Krauss, I. Goldberg, N. Le, 1988, The Journal of clinical investigation.

Cardiovascular disease.

N. Le, 2007, Current opinion in lipidology.

The differential effect of statins on oxidative stress and endothelial function: atorvastatin versus pravastatin.

Dean P. Jones, A. Quyyumi, J. Murrow, 2012, Journal of clinical lipidology.

Editorial comment Hyperlipidaemia and cardiovascular disease

N. Le, 2001 .

The effect of lovastatin on very low-density lipoprotein apolipoprotein B production by the liver in familial combined hyperlipidaemia

J. Cortner, M. Bennett, N. Le, 1993, Journal of Inherited Metabolic Disease.

Effect of ABT-335 (fenofibric acid) on meal-induced oxidative stress in patients with metabolic syndrome.

P. Wilson, N. Le, M. Sweeney, 2013, Atherosclerosis.

36 – A Reduced Model for Very Low Density Lipoprotein Triglyceride Metabolism

S. Grundy, N. Le, M. Berman, 1982 .

8 – Compartmental Models for the Study of Apoprotein B Catabolism in Man

H. Ginsberg, N. Le, W. Brown, 1982 .

Hyperlipidemia and cardiovascular disease: cardiovascular update.

N. Le, 2008, Current opinion in lipidology.

Lipoproteins as biosensors of endothelial oxidative status

N. Le, Monica Farkas-Epperson, 2012 .

What does plasma CRP tell us about peripheral and central inflammation in depression?

D. Goldsmith, M. Tansey, Andrew H. Miller, 2018, Molecular Psychiatry.

Soluble Urokinase Plasminogen Activator Receptor Level Is an Independent Predictor of the Presence and Severity of Coronary Artery Disease and of Future Adverse Events

A. Quyyumi, D. Kremastinos, N. Le, 2014, Journal of the American Heart Association.

Dietary Fructose Reduction Improves Markers of Cardiovascular Disease Risk in Hispanic-American Adolescents with NAFLD

Diego R. Martín, Puneet S. Sharma, N. Le, 2014, Nutrients.

Murine high-fat diet and laser photochemical model of basal deposits in Bruch membrane.

C. Curcio, H. Grossniklaus, N. Le, 2001, Archives of ophthalmology.

Baroreflex dysfunction and augmented sympathetic nerve responses during mental stress in veterans with post‐traumatic stress disorder

B. Rothbaum, S. Norrholm, N. Le, 2017, The Journal of physiology.

Underappreciated Opportunities for High-Density Lipoprotein Particles in Risk Stratification and Potential Targets of Therapy

R. Rosenson, N. Le, M. Davidson, 2015, Cardiovascular Drugs and Therapy.

Effects of oral and intravenous fat load on blood pressure, endothelial function, sympathetic activity, and oxidative stress in obese healthy subjects.

A. Quyyumi, A. Gosmanov, A. Kitabchi, 2010, American journal of physiology. Endocrinology and metabolism.

Risk Factors for Coronary Heart Disease in Diabetic and Nondiabetic Native Americans: The Strong Heart Study

P. Savage, B. Howard, R. Fabsitz, 1992, Diabetes.

Metabolism and proteomics of large and small dense LDL in combined hyperlipidemia: effects of rosuvastatin1[S]

E. Schaefer, S. Turner, N. Le, 2017, Journal of Lipid Research.

Apolipoprotein B metabolism in subjects with deficiency of apolipoproteins CIII and AI. Evidence that apolipoprotein CIII inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo.

R. Norum, I. Goldberg, N. Le, 1986, The Journal of clinical investigation.

CHAPTER 9 – Cholesterol: Concentration, Ratio, and Particle Number

P. Wilson, N. Le, 2009 .

Comparison of the relation of triglyceride-rich lipoproteins and muscular artery compliance in healthy women versus healthy men.

L. Mosca, S. Homma, D. Herrington, 2005, The American journal of cardiology.

Kinetics of chylomicron remnant clearance in normal and in hyperlipoproteinemic subjects.

J. Cortner, N. Le, P. Coates, 1987, Journal of lipid research.

Beneficial effects of designed dietary fatty acid compositions on lipids in triacylglycerol-rich lipoproteins among Chinese patients with type 2 diabetes mellitus.

V. Vaccarino, N. Le, E. Veledar, 2009, Metabolism: clinical and experimental.

Sympathoexcitation and impaired arterial baroreflex sensitivity are linked to vascular inflammation in individuals with elevated resting blood pressure

N. Le, Ida T. Fonkoue, P. Marvar, 2019, Physiological reports.

Effect of Switching From Statin Monotherapy to Ezetimibe/Simvastatin Combination Therapy Compared With Other Intensified Lipid‐Lowering Strategies on Lipoprotein Subclasses in Diabetic Patients With Symptomatic Cardiovascular Disease

P. Wilson, J. Tomassini, N. Le, 2015, Journal of the American Heart Association.

Rosuvastatin Enhances the Catabolism of LDL apoB-100 in Subjects with Combined Hyperlipidemia in a Dose Dependent Manner

E. Schaefer, N. Le, P. Barrett, 2015, Lipids.

Metabolic flexibility differs by body composition in adults.

R. Martorell, K. Narayan, A. Stein, 2021, Clinical nutrition ESPEN.

Symptom severity impacts sympathetic dysregulation and inflammation in post-traumatic stress disorder (PTSD)

B. Rothbaum, J. Bremner, S. Norrholm, 2020, Brain, Behavior, and Immunity.

Dyslipidemia in obese cats.

M. Hoenig, M. Waldron, N. Le, 2008, Domestic animal endocrinology.

The Role of Hepatic Triglyceride Lipase in Primates

I. Goldberg, H. Ginsberg, N. Le, 1983 .

Measuring Postprandial Metabolic Flexibility To Assess Metabolic Health and Disease.

A. Stein, N. Le, Elaine A Yu, 2021, The Journal of nutrition.

The impact of moderate distance recreational running and ageing on cardiac physiology

P. Wilson, Y. Ko, N. Le, 2016, Heart.

Apathy in a high prevalence population of moderate to severe traumatic brain injury: An investigation in Vietnam.

S. McDonald, F. Kumfor, N. Le, 2021, Neuropsychology.

Physical training improves insulin resistance syndrome markers in obese adolescents.

M. Litaker, B. Gutin, N. Le, 2002, Medicine and science in sports and exercise.

Evidence for heterogeneity of low-density lipoprotein metabolism in the cynomolgus monkey.

I. Goldberg, N. Le, W. Brown, 1986, Biochimica et Biophysica Acta.

Postprandial glycemic response differed by early life nutritional exposure in a longitudinal cohort: a single- and multi-biomarker approach

R. Martorell, K. Narayan, A. Stein, 2020, European Journal of Nutrition.

Apolipoprotein C-III protein concentrations and gene polymorphisms in Type 1 diabetes: associations with microvascular disease complications in the DCCT/EDIC cohort.

G. Page, A. Jenkins, T. Lyons, 2005, Journal of diabetes and its complications.

Effects of exercise training and its cessation on components of the insulin resistance syndrome in obese children

M. Litaker, B. Gutin, N. Le, 1999, International Journal of Obesity.

Familial combined hyperlipidaemia: Use of stable isotopes to demonstrate overproduction of very low-density lipoprotein apolipoprotein B by the liver

J. Cortner, M. Bennett, N. Le, 1991, Journal of Inherited Metabolic Disease.

Atherogenic lipid profiles in Filipino adolescents with low body mass index and low dietary fat intake

C. Kuzawa, L. Adair, N. Le, 2003, American journal of human biology : the official journal of the Human Biology Council.

Regulation of serine protease inhibitor Kazal type-5 (SPINK5) gene expression in the keratinocytes

H. Tanii, K. Saijoh, N. Le, 2014, Environmental Health and Preventive Medicine.

Rationale, design, and implementation of aggressive risk factor management in the Stenting and Aggressive Medical Management for Prevention of Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) trial.

A. Nizam, T. Turan, B. Egan, 2012, Circulation. Cardiovascular quality and outcomes.

Changes in lipoprotein concentrations during the development of noninsulin-dependent diabetes mellitus in obese rhesus monkeys (Macaca mulatta).

B. Howard, B. Hansen, N. Le, 1991, The Journal of clinical endocrinology and metabolism.

Glucose and lipid-related biomarkers and the antidepressant response to infliximab in patients with treatment-resistant depression

Andrew H. Miller, N. Le, E. Haroon, 2018, Psychoneuroendocrinology.

Reduced arterial compliance in patients with psychiatric diagnoses

D. Kelly, Erica Duncan, C. Qualls, 2012, Schizophrenia Research.

Quantitative study of alpha-synuclein prion-like spreading in fully oriented reconstructed neural networks reveals non-synaptic dissemination of seeding aggregates

N. Le, J. Peyrin, R. Melki, 2021, bioRxiv.

Effects of psyllium on cholesterol and low-density lipoprotein metabolism in subjects with hypercholesterolemia

B. Howard, T. Miettinen, N. Le, 1997 .

Free oxygen radicals in whole blood correlate strongly with high-sensitivity C-reactive protein.

N. Le, Barry E Eggleston, W. Brown, 2007, Journal of clinical lipidology.

Simvastatin Improved Arterial Compliance in High-Risk Patients

N. Le, W. Brown, Warren W Davis, 2004, Vascular and endovascular surgery.

Relationship between plasma apolipoprotein B concentrations and LDL particle number

N. Le, P. Morris, M. Shapiro, 2014 .

Cardiovascular disease risk factors among American Indians. The Strong Heart Study.

B. Howard, D. Robbins, R. Fabsitz, 1995, American journal of epidemiology.

The Strong Heart Study. A study of cardiovascular disease in American Indians: design and methods.

P. Savage, B. Howard, R. Fabsitz, 1990, American journal of epidemiology.

Visceral adipose tissue and cardiovascular risk factors in obese children.

B. Gutin, N. Le, J. Allison, 1998, The Journal of pediatrics.