P. Brooks

发表

Requirement of vascular integrin alpha v beta 3 for angiogenesis.

D. Cheresh, R. Clark, P. Brooks, 1994, Science.

Integrin alpha(v)beta3 promotes M21 melanoma growth in human skin by regulating tumor cell survival.

F. Mitjans, D. Cheresh, S. Strömblad, 1999, Cancer research.

Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels.

D. Cheresh, P. Brooks, R. Reisfeld, 1994, Cell.

Integrin α v β 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

D. Cheresh, P. Brooks, R. Reisfeld, 1994, Cell.

Temporal exposure of cryptic collagen epitopes within ischemic muscle during hindlimb reperfusion.

H. Yee, P. Brooks, P. Gagne, 2005, The American journal of pathology.

Challenges facing antiangiogenic therapy for cancer: impact of the tumor extracellular environment

P. Brooks, P. Gagne, A. Akalu, 2004, Expert review of anticancer therapy.

Matrix metalloproteinase-9-dependent exposure of a cryptic migratory control site in collagen is required before retinal angiogenesis.

Masanori Hangai, Zena Werb, Z. Werb, 2002, The American journal of pathology.

Vascular integrin alpha(v)beta3: a new prognostic indicator in breast cancer.

E Biganzoli, P. Vermeulen, L. Dirix, 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

Definition of two angiogenic pathways by distinct alpha v integrins.

D. Cheresh, P. Brooks, M. Friedlander, 1995, Science.

Suppression of p53 Activity and p21 WAF1/CIP1 Expression by Vascular Cell Integrin during Angiogenesis

J. Becker, D. Cheresh, S. Strömblad, 1996 .

Thrombin up-regulates cathepsin D which enhances angiogenesis, growth, and metastasis.

S. Karpatkin, P. Brooks, Liang Hu, 2008, Cancer research.

Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

W. Stetler-Stevenson, D. Cheresh, S. Strömblad, 1996, Cell.

New Functions for Non-collagenous Domains of Human Collagen Type IV

Peter C. Brooks, M. Sarras, J. Xu, 2000, The Journal of Biological Chemistry.

Identification of an Endogenously Generated Cryptic Collagen Epitope (XL313) That May Selectively Regulate Angiogenesis by an Integrin Yes-associated Protein (YAP) Mechano-transduction Pathway*

P. Brooks, R. Friesel, Xuehui Yang, 2015, The Journal of Biological Chemistry.

Generation of monoclonal antibodies to cryptic collagen sites by using subtractive immunization.

J. Xu, P. Brooks, J. J. Kim, 2000, Hybridoma.

Plasminogen Activator Inhibitor-1 Regulates Tumor Growth and Angiogenesis*

R. Westrick, D. Lawrence, M. Wong, 2001, The Journal of Biological Chemistry.

Increased shedding of HU177 correlates with worse prognosis in primary melanoma

M. Mazumdar, I. Osman, P. Christos, 2010, Journal of Translational Medicine.

Inhibition of Ovarian Tumor Growth by Targeting the HU177 Cryptic Collagen Epitope.

P. Brooks, F. Muggia, R. Friesel, 2016, The American journal of pathology.

a v b 3 during Angiogenesis

J. Becker, D. Cheresh, S. Strömblad, 1996 .

Cell adhesion molecules in angiogenesis

P. Brooks, 1996, Cancer and Metastasis Reviews.

Fibroblast Growth Factor Signaling in the Vasculature

L. Liaw, P. Brooks, R. Friesel, 2015, Current Atherosclerosis Reports.

Ionizing radiation modulates the exposure of the HUIV26 cryptic epitope within collagen type IV during angiogenesis.

K. Dewyngaert, S. Formenti, S. Lymberis, 2002, International journal of radiation oncology, biology, physics.

Reprogramming of the Ovarian Tumor Stroma by Activation of a Biomechanical ECM Switch

P. Brooks, 2015 .

Generation of a monoclonal antibody to a cryptic site common to both integrin beta1 as well as gelatinase MMP9.

P. Brooks, Jinsong Xu, D. Broek, 2003, Hybridoma and hybridomics.

The HU177 Collagen Epitope Controls Melanoma Cell Migration and Experimental Metastasis by a CDK5/YAP-Dependent Mechanism.

P. Brooks, C. Vary, Liangru Contois, 2018, The American journal of pathology.

An RGDKGE-Containing Cryptic Collagen Fragment Regulates Phosphorylation of Large Tumor Suppressor Kinase-1 and Controls Ovarian Tumor Growth by a Yes-Associated Protein-Dependent Mechanism

P. Sathyanarayana, P. Brooks, C. Vary, 2021 .

Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src

P. Brooks, R. Friesel, I. Prudovsky, 2013, Angiogenesis.

The vitamin-like dietary supplement para-aminobenzoic acid enhances the antitumor activity of ionizing radiation.

S. Formenti, P. Brooks, S. MacDonald, 2006, International journal of radiation oncology, biology, physics.

Contortrostatin, a Homodimeric Disintegrin, Binds to Integrin αvβ5

P. Brooks, F. Markland, M. R. Ritter, 2000 .

A Single Immunoglobulin-like Domain of the Human Neural Cell Adhesion Molecule L1 Supports Adhesion by Multiple Vascular and Platelet Integrins

D. Cheresh, P. Brooks, M. Ginsberg, 1997, The Journal of cell biology.

Vascular Integrin av 1 3 : A New Prognostic Indicator in Breast Cancer 1

P. Vermeulen, L. Dirix, R. Miceli, 2005 .

Use of the 10-day-old chick embryo model for studying angiogenesis.

D. Cheresh, P. Brooks, A. Montgomery, 1999, Methods in molecular biology.

Cooperative Molecular Interactions in the Regulation of Angiogenesis

P. Brooks, L. Hassanieh, Loubna Hassanieh, 2000 .

Consensus guidelines for the use and interpretation of angiogenesis assays

Robert J. Griffin, Federico Bussolino, Mark J. Post, 2018, Angiogenesis.

The chick embryo metastasis model.

P. Brooks, E. Petitclerc, P. C. Brooks, 2001, Methods in molecular medicine.

Role of integrins in angiogenesis.

P. Brooks, P C Brooks, Peter C. Brooks, 1996, European journal of cancer.

Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients

D. Polsky, H. Yee, I. Osman, 2008, Journal of Translational Medicine.

Growth Regulated Oncogene (GRO-α) Is Pivotal in Thrombin-Induced Angiogenesis.

S. Karpatkin, P. Brooks, Liang Hu, 2005 .

UV-Induced Triggering of a Biomechanical Initiation Switch within Collagen Promotes Development of a Melanoma-Permissive Microenvironment in the Skin

P. Brooks, 2012 .

Matrix, Extracellular and Interstitial

P. Brooks, A. Akalu, 2006 .

Procedes et compositions inhibant l'angiogenese

D. Cheresh, P. Brooks, 1997 .

Integrin αVβ3 Promotes M21 Melanoma Growth in Human Skin by Regulating Tumor Cell Survival

F. Mitjans, D. Cheresh, S. Strömblad, 1999 .

Localization of Matrix Metalloproteinase MMP-2 to the Surface of Invasive Cells by Interaction with Integrin αvβ3

W. Stetler-Stevenson, D. Cheresh, S. Strömblad, 1996, Cell.

Extracellular Matrix in the Regulation of Angiogenesis

P. Brooks, Jingsong Xu, J. Xu, 2002 .

Discovery of Novel Small Molecule Inhibitors of VEGF Expression in Tumor Cells Using a Cell-Based High Throughput Screening Platform

Jean Hedrick, S. Peltz, T. Davis, 2016, PloS one.

Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo

Jingsong Xu, Masanori Hangai, George E. Davis, 2001, The Journal of cell biology.

Impact of the non‐cellular tumor microenvironment on metastasis: Potential therapeutic and imaging opportunities

P. Brooks, Alexandra Cretu, 2007, Journal of cellular physiology.

Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin.

F. Sarkar, D. Visscher, R. Klemke, 1995, The Journal of clinical investigation.

CAS/Crk Coupling Serves as a “Molecular Switch” for Induction of Cell Migration

K. Vuori, R. Klemke, D. Cheresh, 1998, The Journal of cell biology.

Disruption of Angiogenesis by PEX, a Noncatalytic Metalloproteinase Fragment with Integrin Binding Activity

D. Cheresh, P. Brooks, M. Friedlander, 1998, Cell.

Review: The Integrin αvβ3: Angiogenesis and Apoptosis

D. Cheresh, P. Brooks, J. Varner, 1995 .

Definition of Two Angiogenic Pathways by Distinct αv Integrins

David A. Cheresh, Martin Friedlander, Peter C. Brooks, 1995, Science.

Rapid vascular regrowth in tumors after reversal of VEGF inhibition.

D. McDonald, T. Inai, B. Sennino, 2006, The Journal of clinical investigation.

Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo

Richard A. Lang, Peter C. Brooks, R. Lang, 2002, Proceedings of the National Academy of Sciences of the United States of America.

An RGDKGE containing cryptic collagen fragment regulates phosphorylation of LATS1 and controls ovarian tumor growth by a YAP-dependent mechanism.

P. Sathyanarayana, P. Brooks, C. Vary, 2020, The American journal of pathology.

Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis.

J. Becker, D. Cheresh, S. Strömblad, 1996, The Journal of clinical investigation.

Matrix metalloproteinases in peripheral vascular disease.

Robert W. Thompson, P. Brooks, B. Muhs, 2007, Journal of vascular surgery.

BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses

B. Conley, L. Liaw, P. Brooks, 2015, PloS one.

Cooperative Interactions Between Integrins and Growth Factor Signaling in Pathological Angiogenesis

P. Brooks, J. Roth, E. Tweedie, 2010 .

Effect of Reproductive Hormones on Ovarian Epithelial Tumors: II. Effect on Angiogenic Activity

Mimi C. Yu, P. Brooks, L. Dubeau, 2002, Cancer biology & therapy.

Cryptic collagen elements as signaling hubs in the regulation of tumor growth and metastasis

P. Brooks, Jennifer M. Caron, Xianghua Han, 2020, Journal of cellular physiology.

Inhibition of tumor-associated αvβ3 integrin regulates the angiogenic switch by enhancing expression of IGFBP-4 leading to reduced melanoma growth and angiogenesis in vivo

L. Liaw, P. Brooks, R. Friesel, 2014, Angiogenesis.

AP-1 (Fra-1/c-Jun)-mediated Induction of Expression of Matrix Metalloproteinase-2 Is Required for 15(S)-Hydroxyeicosatetraenoic Acid-induced Angiogenesis*

G. Rao, P. Brooks, Venkatesh Kundumani-Sridharan, 2010, The Journal of Biological Chemistry.

Biomechanical ECM Switches and Tumor Metastasis

P. Brooks, C. Vary, Jacquelyn J. Ames, 2011 .

REVIEW: the integrin alpha V beta 3: angiogenesis and apoptosis.

D. Cheresh, P. Brooks, J. Varner, 1995, Cell adhesion and communication.

Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo

C. Damsky, S. Deming, D. Cheresh, 1995, The Journal of cell biology.

The Cochaperone p23 Differentially Regulates Estrogen Receptor Target Genes and Promotes Tumor Cell Adhesion and Invasion

M. Garabedian, R. Schneider, S. Braunstein, 2006, Molecular and Cellular Biology.

Inhibition of experimental metastasis by targeting the HUIV26 cryptic epitope in collagen.

S. Formenti, P. Brooks, P. Gagne, 2006, The American journal of pathology.

Inhibition of angiogenesis and tumor metastasis by targeting a matrix immobilized cryptic extracellular matrix epitope in laminin.

P. Brooks, A. Akalu, L. Liebes, 2007, Cancer research.

Epitope in Laminin Targeting a Matrix Immobilized Cryptic Extracellular Matrix Inhibition of Angiogenesis and Tumor Metastasis

P. Brooks, A. Akalu, L. Liebes, 2007 .

Contact with fibrillar collagen inhibits melanoma cell proliferation by up-regulating p27KIP1.

K. Weinberg, P. Henriet, Y. DeClerck, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Cooperative Integrin Interactions in the Regulation of Tumor Metastasis

P. Brooks, 2002 .

Recombinant (cid:2) 2(IV)NC1 Domain Inhibits Tumor Cell-Extracellular Matrix Interactions, Induces Cellular Senescence, and Inhibits Tumor Growth in Vivo

S. Formenti, P. Brooks, S. MacDonald, 2005 .

Integrins as "functional hubs" in the regulation of pathological angiogenesis.

P. Brooks, A. Akalu, Liangru W. Contois, 2009, Seminars in cancer biology.

Inhibition of Angiogenesis in Vivo by Plasminogen Activator Inhibitor-1*

D. Lawrence, M. Wong, S. Stefansson, 2001, The Journal of Biological Chemistry.

The Role of Integrin αvβ3 in Cell Survival and Angiogenesis

J. Becker, D. Cheresh, S. Strömblad, 1997 .

Targeting integrins for the control of tumour angiogenesis

P. Brooks, A. Akalu, Alexandra Cretu, 2005, Expert opinion on investigational drugs.

Integrin Receptors and the Regulation of Angiogenesis

P. Brooks, D. Rodriguez, 2002 .

Thrombin induces neoangiogenesis in the chick chorioallantoic membrane

S. Karpatkin, P. Brooks, M. Caunt, 2003, Journal of thrombosis and haemostasis : JTH.

Shedding of Distinct Cryptic Collagen Epitope (HU177) in Sera of Melanoma Patients

M. Mazumdar, D. Polsky, D. Bajorin, 2008, Clinical Cancer Research.

Disruption of Endothelial Cell Interactions with the Novel HU177 Cryptic Collagen Epitope Inhibits Angiogenesis

S. Formenti, P. Brooks, P. Gagne, 2007, Clinical Cancer Research.

Twist is required for thrombin-induced tumor angiogenesis and growth.

S. Karpatkin, P. Brooks, Liang Hu, 2008, Cancer research.

Growth-regulated oncogene is pivotal in thrombin-induced angiogenesis.

Liang Hu, S. Karpatkin, P. Brooks, 2006, Cancer research.

Improved Survival Outcomes in Cancer Patients with Hereditary Hemorrhagic Telangiectasia

Kathleen M. Fairfield, K. Fairfield, P. Brooks, 2013, Cancer Epidemiology, Biomarkers & Prevention.

Insulin-like growth factor receptor cooperates with integrin alpha v beta 5 to promote tumor cell dissemination in vivo.

R. Klemke, M. Schwartz, D. Cheresh, 1997, The Journal of clinical investigation.

The chimeric human/mouse model of angiogenesis.

P. Brooks, E. Petitclerc, T. von Schalscha, 2000, Methods in molecular biology.

Contortrostatin, a homodimeric disintegrin, binds to integrin alphavbeta5.

Q. Zhou, P. Brooks, F. Markland, 2000, Biochemical and biophysical research communications.

Membrane Type I Matrix Metalloproteinase Usurps Tumor Growth Control Imposed by the Three-Dimensional Extracellular Matrix

S. Weiss, P. Brooks, M. Long, 2003, Cell.

Antiintegrin av,83 blocks human breast cancer growth and angiogenesis in human skin

F. Sarkar, D. Visscher, R. Klemke, 2013 .

Cryptic collagen IV promotes cell migration and adhesion in myeloid leukemia

P. Sathyanarayana, P. Brooks, Amanda J. Favreau, 2014, Cancer medicine.

Inhibition of tumor-associated αvβ3 integrin regulates the angiogenic switch by enhancing expression of IGFBP-4 leading to reduced melanoma growth and angiogenesis in vivo

L. Liaw, P. Brooks, R. Friesel, 2014, Angiogenesis.

Endoglin regulates cancer-stromal cell interactions in prostate tumors.

B. Conley, A. Terzić, R. Bergan, 2011, Cancer research.

Methods for Analyzing Tumor Angiogenesis in the Chick Chorioallantoic Membrane Model.

L. Liaw, P. Brooks, Jacquelyn J. Ames, 2016, Methods in molecular biology.

Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src

P. Brooks, R. Friesel, I. Prudovsky, 2013, Angiogenesis.

Recombinant alpha2(IV)NC1 domain inhibits tumor cell-extracellular matrix interactions, induces cellular senescence, and inhibits tumor growth in vivo.

S. Formenti, P. Brooks, S. MacDonald, 2005, The American journal of pathology.

Pathological Angiogenesis: An Overview

R. Desai, P. Brooks, R. Friesel, 2014 .

Eukaryotic expression cloning with an antimetastatic monoclonal antibody identifies a tetraspanin (PETA-3/CD151) as an effector of human tumor cell migration and metastasis.

J. M. Lin, J. Quigley, P. Brooks, 1999, Cancer research.