M. Scanlon

发表

A novel two-chain proteinase inhibitor generated by circularization of a multidomain precursor protein

David J. Craik, Marilyn A. Anderson, Martin J. Scanlon, 1999, Nature Structural Biology.

Substituted 1-methyl-4-phenylpyrrolidin-2-ones - Fragment-based design of N-methylpyrrolidone-derived bromodomain inhibitors.

R. Johnstone, I. Jennings, P. Thompson, 2020, European journal of medicinal chemistry.

Structure-Activity Studies of β-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.

R. Norton, R. Anders, S. McGowan, 2016, Journal of molecular biology.

Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1

Jennifer L. Martin, C. Morton, M. Scanlon, 2017, PloS one.

The solution structure of C1-T1, a two-domain proteinase inhibitor derived from a circular precursor protein from Nicotiana alata.

D. Craik, M. Anderson, H. Schirra, 2001, Journal of molecular biology.

Design and Evaluation of the Performance of an NMR Screening Fragment Library

Martin J. Scanlon, Bradley C. Doak, Craig J. Morton, 2013 .

Structure of a putative ancestral protein encoded by a single sequence repeat from a multidomain proteinase inhibitor gene from Nicotiana alata.

D. Craik, M. Anderson, M. Scanlon, 1999, Structure.

Solution structure and proposed binding mechanism of a novel potassium channel toxin κ-conotoxin PVIIA

David J. Craik, Martin J. Scanlon, David Naranjo, 1997 .

Design, Synthesis, and Characterization of Cyclic Peptidomimetics of the Inducible Nitric Oxide Synthase Binding Epitope That Disrupt the Protein-Protein Interaction Involving SPRY Domain-Containing Suppressor of Cytokine Signaling Box Protein (SPSB) 2 and Inducible Nitric Oxide Synthase.

J. Baell, R. Norton, P. Thompson, 2016, Journal of medicinal chemistry.

Backbone assignments of the 34 kDa ketopantoate reductase from E. coli

M. Scanlon, J. Simpson, S. Headey, 2008, Biomolecular NMR assignments.

A critical evaluation of pyrrolo[2,3-d]pyrimidine-4-amines as Plasmodium falciparum apical membrane antigen 1 (AMA1) inhibitors

Shane M. Devine, R. Norton, R. Anders, 2014 .

The ways and means of fragment-based drug design.

R. Norton, M. Scanlon, B. Doak, 2016, Pharmacology & therapeutics.

The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors

M. Scanlon, B. Heras, O. Ilyichova, 2019, Molecules.

Targeting Bacterial Dsb Proteins for the Development of Anti-Virulence Agents

M. Scanlon, B. Heras, J. Paxman, 2016, Molecules.

Application of fragment-based screening to the design of inhibitors of Escherichia coli DsbA.

Jennifer L. Martin, M. Scanlon, B. Heras, 2015, Angewandte Chemie.

A simplified liquid chromatography assay for the quantitation of halofantrine and desbutylhalofantrine in plasma and identification of a degradation product of desbutylhalofantrine formed under alkaline conditions.

C. Porter, M. Scanlon, W. Charman, 1995, Journal of pharmaceutical and biomedical analysis.

The Dotted Cap Notation: A concise notation for describing variegated dendrimers

Benjamin P. Roberts, D. Chalmers, G. Krippner, 2008 .

Parallel Screening of Low Molecular Weight Fragment Libraries

Olan Dolezal, Janet Newman, Jerome Wielens, 2013, Journal of biomolecular screening.

Fatty Acid-Binding Protein 5 Mediates the Uptake of Fatty Acids, but not Drugs, Into Human Brain Endothelial Cells.

C. Porter, M. Scanlon, J. Nicolazzo, 2017, Journal of Pharmacy and Science.

Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe

Shane M. Devine, R. Norton, S. McGowan, 2019, ChemMedChem.

Structure and dynamics of apical membrane antigen 1 from Plasmodium falciparum FVO.

Shane M. Devine, R. Norton, Wei Yang, 2014, Biochemistry.

Binding of a pyrimidine RNA base-mimic to SARS-CoV-2 nonstructural protein 9

S. Perlman, J. Rossjohn, D. Littler, 2021, Journal of Biological Chemistry.

Cyclic Hexapeptide Mimics of the LEDGF Integrase Recognition Loop in Complex with HIV‐1 Integrase

M. Parker, J. Wielens, P. Thompson, 2018, ChemMedChem.

Synthesis and elaboration of N-methylpyrrolidone as an acetamide fragment substitute in bromodomain inhibition.

R. Johnstone, I. Jennings, P. Thompson, 2019, Bioorganic & medicinal chemistry.

Fatty Acid-Binding Protein 5 at the Blood–Brain Barrier Regulates Endogenous Brain Docosahexaenoic Acid Levels and Cognitive Function

P. Marriott, C. Porter, M. Scanlon, 2016, The Journal of Neuroscience.

Fatty Acid Binding Proteins: Potential Chaperones of Cytosolic Drug Transport in the Enterocyte?

C. Porter, M. Scanlon, N. Trevaskis, 2011, Pharmaceutical Research.

Colloidal characteristics and formulation of pure protein particulate vaccines

P. White, C. Pouton, B. Boyd, 2012, The Journal of pharmacy and pharmacology.

Solution structure and proposed binding mechanism of a novel potassium channel toxin kappa-conotoxin PVIIA.

D. Craik, R. Lewis, M. Scanlon, 1997, Structure.

The Cysteine-rich Secretory Protein Domain of Tpx-1 Is Related to Ion Channel Toxins and Regulates Ryanodine Receptor Ca2+ Signaling*

M. O’Bryan, J. Swarbrick, M. Scanlon, 2006, Journal of Biological Chemistry.

Structural and functional analysis of the Josephin domain of the polyglutamine protein ataxin-3.

Michelle K. M. Chow, J. Whisstock, S. Bottomley, 2004, Biochemical and biophysical research communications.

Blind man's bluff - Elaboration of fragment hits in the absence of structure for the development of antitrypsin deficiency inhibitors

S. Bottomley, M. Scanlon, M. Pearce, 2013 .

Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens

Jennifer L. Martin, M. Scanlon, B. Heras, 2017, Antioxidants & redox signaling.

Complex with a Collagen-mimetic Peptide 1 I Domain in α The Structure of Integrin Protein Structure and Folding :

P. McEwan, J. Emsley, T. Mulhern, 2013 .

Inhibitors of BCATm: A Tough Nut To Crack.

M. Scanlon, 2015, Journal of medicinal chemistry.

Binding of CFA/I Pili of Enterotoxigenic Escherichia coli to Asialo-GM1 Is Mediated by the Minor Pilin CfaE

J. Riches, G. Ulett, M. Scanlon, 2016, Infection and Immunity.

Fatty Acid Binding Proteins Expressed at the Human Blood–Brain Barrier Bind Drugs in an Isoform-Specific Manner

C. Porter, M. Scanlon, J. Nicolazzo, 2015, Pharmaceutical Research.

Fatty Acid-Binding Protein 5 Facilitates the Blood-Brain Barrier Transport of Docosahexaenoic Acid.

Yui Yamamoto, C. Porter, M. Scanlon, 2015, Molecular pharmaceutics.

Self-Micellization of Gemfibrozil 1-O-β Acyl Glucuronide in Aqueous Solution

David M. Shackleford, R. Prankerd, M. Scanlon, 2003, Pharmaceutical Research.

Molecular Dynamics of Variegated Polyamide Dendrimers

Benjamin P. Roberts, D. Chalmers, G. Krippner, 2009 .

Molecular Dynamics of Poly(L-lysine) Dendrimers with Naphthalene Disulfonate Caps

Benjamin P. Roberts, D. Chalmers, G. Krippner, 2009 .

Molecular Insights into the Interaction Between the SPRY Domain-Containing SOCS Box Protein SPSB2 and Peptides Based on the Binding Motif from iNOS

R. Norton, M. Scanlon, S. Nicholson, 2017 .

19F NMR as a Probe of Ligand Interactions with the iNOS Binding site of SPRY Domain‐Containing SOCS Box Protein 2

J. Baell, R. Norton, M. Scanlon, 2014, Chemical biology & drug design.

Δ-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities.

I. Vetter, M. Aguilar, M. Cooper, 2017, Angewandte Chemie.

Applications of NMR spectroscopy in FBDD

M. Scanlon, B. Doak, B. Mohanty, 2018 .

HN, N, Cα and Cβ assignments of the two periplasmic domains of Neisseria meningitidis DsbD

M. Scanlon, B. Heras, B. Mohanty, 2017, Biomolecular NMR Assignments.

Determinants of Proteolysis and Cell-Binding for the Shigella flexneri Cytotoxin, SigA

E. Chua, M. Scanlon, B. Adler, 2015, Current Microbiology.

Determination of ligand binding modes in weak protein–ligand complexes using sparse NMR data

G. King, D. Chalmers, M. Scanlon, 2016, Journal of Biomolecular NMR.

Development of inhibitors of Plasmodium falciparum apical membrane antigen 1 based on fragment screening

Shane M. Devine, R. Norton, R. Anders, 2013 .

Methyl probes in proteins for determining ligand binding mode in weak protein–ligand complexes

M. Scanlon, M. Mobli, B. Doak, 2022, Scientific Reports.

The binding interaction of synthetic ozonide antimalarials with natural and modified beta-cyclodextrins.

Susan A Charman, Martin J Scanlon, R. Prankerd, 2006, Journal of pharmaceutical sciences.

Characterization of the DsbA oxidative folding catalyst from Pseudomonas aeruginosa reveals a highly oxidizing protein that binds small molecules.

Jennifer L. Martin, M. Scanlon, B. Heras, 2010, Antioxidants & redox signaling.

Difficult macrocyclizations: new strategies for synthesizing highly strained cyclic tetrapeptides.

Douglas A. Horton, Martin Scanlon, D. Craik, 2003, Organic letters.

Conformational selection of inhibitors and substrates by proteolytic enzymes: implications for drug design and polypeptide processing.

D. Fairlie, M. Scanlon, R. Reid, 2000, Journal of medicinal chemistry.

Assignments of human integrin α1I domain in the apo and Mg2+ bound states

J. Emsley, M. Scanlon, B. Mohanty, 2014, Biomolecular NMR assignments.

Characterization of the N-methyltransferase activities of the multifunctional polypeptide cyclosporin synthetase.

T. Velkov, M. Scanlon, E. Yuriev, 2011, Chemistry & biology.

DSB proteins and bacterial pathogenicity

Jennifer L. Martin, M. Scanlon, B. Heras, 2009, Nature Reviews Microbiology.

Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief

Pierangelo Geppetti, Martin J. Scanlon, Christopher J. H. Porter, 2017, Science Translational Medicine.

Pharmaceutical Applications of NMR

D. Craik, M. Scanlon, 2000 .

Conformationally constrained macrocycles that mimic tripeptide beta-strands in water and aprotic solvents.

Martin J Scanlon, D. Fairlie, M. Scanlon, 2002, Journal of the American Chemical Society.

Ligand-induced conformational change of Plasmodium falciparum AMA1 detected using 19F NMR.

Shane M. Devine, M. Foley, R. Norton, 2014, Journal of medicinal chemistry.

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

W. Alexander, R. Dobson, A. Wilks, 2014, Proceedings of the National Academy of Sciences.

Structure and function of the oxidoreductase DsbA1 from Neisseria meningitidis.

T. Beddoe, J. Rossjohn, J. Vivian, 2009, Journal of molecular biology.

Structural basis for the inhibition of poxvirus assembly by the antibiotic rifampicin

M. Gunzburg, M. Scanlon, D. Garriga, 2018, Proceedings of the National Academy of Sciences.

Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module

T. Lithgow, M. Wilce, M. Scanlon, 2015, Scientific Reports.

Isolation, solution structure, and insecticidal activity of kalata B2, a circular protein with a twist: do Möbius strips exist in nature?

Clement Waine, Cameron V. Jennings, Martin J Scanlon, 2005, Biochemistry.

Peptide epitope binding and fluorescence quenching with the anti-mucin antibody C595.

M. Price, M. Scanlon, S. Tendler, 1992, Cancer letters.

Structural and computational investigations of the conformation of antigenic peptide fragments of human polymorphic epithelial mucin.

D. Jackson, M. Price, M. Scanlon, 1992, The Biochemical journal.

The mucin antigens: what are we measuring?

M. Price, M. Scanlon, P. Sibley, 1991, Disease markers.

Primary sequence determination and molecular modelling of the variable region of an antiMUC1 mucin monoclonal antibody.

M. Price, M. Scanlon, G. Denton, 1995, European journal of cancer.

Characterization of the drug binding specificity of rat liver fatty acid binding protein.

T. Velkov, C. Porter, M. Scanlon, 2008, Journal of medicinal chemistry.

An improved method for the purification of rat liver-type fatty acid binding protein from Escherichia coli.

T. Velkov, R. Prankerd, C. Porter, 2005, Protein expression and purification.

Probing the fibrate binding specificity of rat liver fatty acid binding protein.

J. Wielens, T. Velkov, D. Chalmers, 2009, Journal of medicinal chemistry.

Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein.

Jerome Wielens, Christopher J H Porter, Martin J Scanlon, 2014, ACS chemical biology.

NMR solution structure of the RNA-binding peptide from human immunodeficiency virus (type 1) Rev.

D. Craik, D. Fairlie, M. West, 1995, Biochemistry.

Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation

Martin J. Scanlon, Amy L. Robertson, Stephen P. Bottomley, 2010, Proceedings of the National Academy of Sciences.

Probing the flexibility of the DsbA oxidoreductase from Vibrio cholerae--a 15N - 1H heteronuclear NMR relaxation analysis of oxidized and reduced forms of DsbA.

Edward J. d'Auvergne, T. Velkov, R. Prankerd, 2007, Journal of molecular biology.

Reduced blood‐brain barrier expression of fatty acid‐binding protein 5 is associated with increased vulnerability of APP/PS1 mice to cognitive deficits from low omega‐3 fatty acid diets

P. Marriott, C. Porter, M. Scanlon, 2018, Journal of neurochemistry.

Distinct binding properties of TIAR RRMs and linker region

M. Gorospe, Henry S. Kim, Yano M. K. Yoga, 2013, RNA biology.

Targeting virulence not viability in the search for future antibacterials.

Jennifer L. Martin, M. Scanlon, B. Heras, 2015, British journal of clinical pharmacology.

Dietary docosahexaenoic acid supplementation enhances expression of fatty acid‐binding protein 5 at the blood–brain barrier and brain docosahexaenoic acid levels

P. Marriott, C. Porter, M. Scanlon, 2018, Journal of neurochemistry.

Redox‐stable cyclic peptide inhibitors of the SPSB2–iNOS interaction

J. Baell, R. Norton, P. Thompson, 2016, FEBS letters.

Solution NMR characterization of apical membrane antigen 1 and small molecule interactions as a basis for designing new antimalarials

Shane M. Devine, R. Norton, H. Atreya, 2016, Journal of molecular recognition : JMR.

Enhancing the immunogenicity and modulating the fine epitope recognition of antisera to a helical group A streptococcal peptide vaccine candidate from the M protein using lipid‐core peptide technology

I. Toth, M. Good, M. Scanlon, 2002, Immunology and cell biology.

The 1.2 Å resolution crystal structure of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera-toxin production.

Jennifer L. Martin, M. Scanlon, B. Heras, 2012, Acta crystallographica. Section D, Biological crystallography.

The Interaction of Lipophilic Drugs with Intestinal Fatty Acid-binding Protein*

J. Wielens, T. Velkov, C. Porter, 2005, Journal of Biological Chemistry.

Sent packing: protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility

Jennifer L. Martin, C. Morton, M. Scanlon, 2015, Acta crystallographica. Section D, Biological crystallography.

Fatty acid binding proteins shape the cellular response to activation of the glucocorticoid receptor

R. Weaver, C. Porter, M. Scanlon, 2021, bioRxiv.

A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor alpha agonists.

R. Weaver, L. Vuillard, C. Porter, 2019 .

A ligand-induced structural change in fatty acid–binding protein 1 is associated with potentiation of peroxisome proliferator–activated receptor α agonists

R. Weaver, L. Vuillard, C. Porter, 2018, The Journal of Biological Chemistry.

Fatty Acid-binding Proteins 1 and 2 Differentially Modulate the Activation of Peroxisome Proliferator-activated Receptor α in a Ligand-selective Manner*

T. Velkov, D. Jans, K. Wagstaff, 2015, The Journal of Biological Chemistry.

Preparation, crystallization and preliminary X-ray diffraction analysis of two intestinal fatty-acid binding proteins in the presence of 11-(dansylamino)undecanoic acid.

M. Parker, J. Wielens, Aisha Laguerre, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Characterization of lipophilic drug binding to rat intestinal fatty acid binding protein

T. Velkov, C. Porter, M. Scanlon, 2009, Molecular and Cellular Biochemistry.

Examination of the role of intestinal fatty acid-binding protein in drug absorption using a parallel artificial membrane permeability assay.

T. Velkov, Aisha Laguerre, C. Porter, 2007, Chemistry & biology.

The Structure of Integrin α1I Domain in Complex with a Collagen-mimetic Peptide*

P. McEwan, J. Emsley, T. Mulhern, 2013, The Journal of Biological Chemistry.

The Role of Oxidoreductases in Determining the Function of the Neisserial Lipid A Phosphoethanolamine Transferase Required for Resistance to Polymyxin

Jhuma Ganguly, Martin J. Scanlon, Parastoo Azadi, 2014, PloS one.

The Structure of the Bacterial Oxidoreductase Enzyme DsbA in Complex with a Peptide Reveals a Basis for Substrate Specificity in the Catalytic Cycle of DsbA Enzymes*

S. Bottomley, J. Rossjohn, N. Borg, 2009, The Journal of Biological Chemistry.

Solution structure and DNA binding of the catalytic domain of the large serine resolvase TnpX

M. Wilce, J. Rood, M. Scanlon, 2015, Journal of molecular recognition : JMR.

The first total synthesis and solution structure of a polypeptin, PE2, a cyclic lipopeptide with broad spectrum antibiotic activity.

R. Nation, T. Velkov, Jian Li, 2017, Organic & biomolecular chemistry.

Structure of the Chicken CD3ϵδ/γ Heterodimer and Its Assembly with the αβT Cell Receptor*

J. Kaufman, J. McCluskey, J. Rossjohn, 2014, The Journal of Biological Chemistry.

HN, N, Cα and Cβ assignments of the two periplasmic domains of Neisseria meningitidis DsbD

M. Scanlon, B. Mohanty, Martin L. Williams, 2017, Biomolecular NMR Assignments.

Multidimensional Nuclear Magnetic Resonance of Biomolecules

D. Craik, M. Scanlon, J. Horne, 2008 .

Three-dimensional structure in solution of the polypeptide cardiac stimulant anthopleurin-A.

R. Norton, P. K. Pallaghy, M. Scanlon, 1995, Biochemistry.

Solution structure of BSTI: a new trypsin inhibitor from skin secretions of Bombina bombina.

D. Craik, K. Rosengren, N. Daly, 2001, Biochemistry.

Promiscuous 2-aminothiazoles (PrATs): a frequent hitting scaffold.

J Willem M Nissink, Jonathan B Baell, Martin J Scanlon, 2015, Journal of medicinal chemistry.

Crystal structure of the HIV‐1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site

M. Parker, J. Deadman, J. Wielens, 2010, FEBS letters.

Controlled Construction of Cyclic d / l Peptide Nanorods.

P. Thompson, D. Chalmers, M. Scanlon, 2018, Angewandte Chemie.

Controlled Construction of Cyclic d / l Peptide Nanorods

P. Thompson, D. Chalmers, M. Scanlon, 2018, Angewandte Chemie.

Interrogating fragments using a protein thermal shift assay

Jennifer L. Martin, M. Scanlon, R. McMahon, 2013 .

Detection and Prevention of Aggregation-based False Positives in STD-NMR-based Fragment Screening

M. Scanlon, E. Yuriev, B. Capuano, 2013 .

A Marine Snail Neurotoxin Shares with Scorpion Toxins a Convergent Mechanism of Blockade on the Pore of Voltage-Gated K Channels

M. Scanlon, Esperanza García, D. Naranjo, 1999, The Journal of general physiology.

Solution structure of the cardiostimulant polypeptide anthopleurin-B and comparison with anthopleurin-A.

R. Norton, P. K. Pallaghy, M. Scanlon, 1995, Structure.

Fatty Acid Binding Proteins Expressed at the Human Blood–Brain Barrier Bind Drugs in an Isoform-Specific Manner

C. Porter, M. Scanlon, J. Nicolazzo, 2015, Pharmaceutical Research.

Molecular Insights into the Interaction between Plasmodium falciparum Apical Membrane Antigen 1 and an Invasion-Inhibitory Peptide

R. Norton, N. Cowieson, R. Anders, 2014, PloS one.

Fragment-Based Discovery of Inhibitors of the Bacterial DnaG-SSB Interaction

N. Dixon, G. Otting, Zhi-Qiang Xu, 2018, Antibiotics.

The structural impact of a polyglutamine tract is location-dependent.

Amy L. Robertson, S. Bottomley, M. Scanlon, 2008, Biophysical journal.

The three-dimensional solution structure of NaD1, a new floral defensin from Nicotiana alata and its application to a homology model of the crop defense protein alfAFP.

D. Craik, H. Schirra, F. T. Lay, 2003, Journal of molecular biology.

Cyclooligomerization of Thiazole-Containing Tetrapeptides. Symmetrical Macrocycles with up to 76 Amino Acids

D. Fairlie, M. Scanlon, L. Gahan, 1999 .

Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor.

N. Daly, M. Scanlon, P. Kroon, 1995, Proceedings of the National Academy of Sciences of the United States of America.

A Backbone Linker for BOC-Based Peptide Synthesis and On-Resin Cyclization: Synthesis of Stylostatin 1(,).

W. Meutermans, M. Smythe, M. Scanlon, 1999, The Journal of organic chemistry.

Rapid elaboration of fragments into leads by X-ray crystallographic screening of parallel chemical libraries (REFiLx).

Jennifer L. Martin, M. Scanlon, B. Heras, 2020, Journal of medicinal chemistry.

Fragment‐Based Design of Ligands Targeting a Novel Site on the Integrase Enzyme of Human Immunodeficiency Virus 1

M. Parker, J. Deadman, J. Wielens, 2011, ChemMedChem.

Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores.

M. Scanlon, O. Ilyichova, B. Doak, 2023, RSC medicinal chemistry.

Structural and Biochemical Characterization of the Oxidoreductase NmDsbA3 from Neisseria meningitidis*

Amy L. Robertson, S. Bottomley, T. Beddoe, 2008, Journal of Biological Chemistry.

Propargyloxyproline Regio- and Stereoisomers for Click-Conjugation of Peptides: Synthesis and Application in Linear and Cyclic Peptides

M. Parker, J. Wielens, Lei Zhang, 2015 .

Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds.

M. Scanlon, O. Ilyichova, Geqing Wang, 2021, Bioorganic & medicinal chemistry.

Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes

Jennifer L. Martin, D. Fairlie, L. Premkumar, 2013, PloS one.

Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra-Terminal Domain.

J. Mackay, M. Gunzburg, M. Scanlon, 2020, Journal of medicinal chemistry.

Novel small molecules that increase the susceptibility of Neisseria gonorrhoeae to cationic antimicrobial peptides by inhibiting lipid A phosphoethanolamine transferase

M. Scanlon, K. Stubbs, A. Vrielink, 2022, The Journal of antimicrobial chemotherapy.

Fluoromethylketone-fragment conjugates designed as covalent modifiers of EcDsbA are atypical substrates

M. Scanlon, O. Ilyichova, J. Harper, 2022 .

NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide–dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei

Jennifer L. Martin, R. B. Fenwick, M. Scanlon, 2020, Journal of Biomolecular NMR.

Small molecule inhibitors of disulfide bond formation by the bacterial DsbA-DsbB dual enzyme system.

C. Robinson, Jennifer L. Martin, D. Fairlie, 2015, ACS chemical biology.

Protein unfolding is essential for cleavage within the α-helix of a model protein substrate by the serine protease, thrombin.

Amy L. Robertson, S. Bottomley, M. Scanlon, 2016, Biochimie.

Synthesis of unsymmetrical 1,1'-disubstituted bis(1,2,3-triazole)s using monosilylbutadiynes.

M. Scanlon, B. Doak, J. Simpson, 2011, Organic letters.