M. Saindane

发表

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice

Xiaotao Lu, Alexandra Schäfer, Ralph S. Baric, 2020, Science Translational Medicine.

Synthesis and Evaluation of Novel Tetrahydronaphthyridine CXCR4 Antagonists with Improved Drug-like Profiles.

Eric J Miller, Eric J. Miller, C. A. Derdeyn, 2022, Journal of medicinal chemistry.

Small-Molecule Antiviral β-d-N4-Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance

R. Baric, A. Kolykhalov, T. Sheahan, 2019, Journal of Virology.

Discovery of a Fluorinated Enigmol Analog with Enhanced in Vivo Pharmacokinetic and Anti-Tumor Properties.

Eric J Miller, D. Liotta, M. Natchus, 2016, ACS medicinal chemistry letters.

Discovery of Tetrahydroisoquinoline-Containing CXCR4 Antagonists with Improved in Vitro ADMET Properties.

Eric J Miller, D. Liotta, C. Sum, 2018, Journal of medicinal chemistry.

Discovery of tetrahydroisoquinoline-based CXCR4 antagonists.

J. Snyder, D. Liotta, M. Natchus, 2013, ACS medicinal chemistry letters.

Development of a novel progesterone analog in the treatment of traumatic brain injury

D. Stein, D. Liotta, I. Sayeed, 2019, Neuropharmacology.

SARS-CoV-2 VOC type and biological sex affect molnupiravir efficacy in severe COVID-19 dwarf hamster model

R. Plemper, Julien Sourimant, R. Cox, 2022, Nature Communications.

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 and multiple endemic, epidemic and bat coronavirus

Alexandra Schäfer, Ralph S. Baric, Amy C. Sims, 2020, bioRxiv.

A synthetic route to forskolin

M. Saindane, B. H. Jaynes, F. Ziegler, 1987 .

A simple, efficient synthesis of 3-substituted furans

D. Liotta, M. Saindane, W. Ott, 1983 .

Synthetic applications of 2-phenylselenenylenones—III

D. Liotta, M. Saindane, C. Barnum, 1985 .

A C6, C7 oxygen functionalized intermediate for the synthesis of forskolin: stereochemical control in an intramolecular Diels-Alder reaction

M. Saindane, B. H. Jaynes, F. Ziegler, 1985 .

3-Alkylfurans as useful synthetic equivalents for substituted δ2-butenolides

D. Liotta, M. Saindane, L. Waykole, 1983 .

Synthesis and antibacterial activity of some novel 1-substituted 1,4-dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic acids. Potent antistaphylococcal agents.

P. Pennock, M. Reuman, M. Saindane, 1995, Journal of medicinal chemistry.

A stereoselective synthesis of BMS-262084, an azetidinone-based tryptase inhibitor.

M. Saindane, B. Zheng, Brian Burke, 2002, The Journal of organic chemistry.

New probes for electron-transfer processes. Evidence supporting the single-electron-transfer mechanism in additions of carbanions to dienones

D. Liotta, M. Saindane, L. Waykole, 1983 .

Flavanoids-IV-stereochemistry of cyanomaclurin : Synthesis of trimethyl ether of (±) epicyanomaclurin☆

M. Saindane, K. G. Marathe, 1975 .

Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase: synthesis, structure-activity relationships, and pharmacokinetics.

J. Ndungu, J. Snyder, R. Plemper, 2012, Journal of medicinal chemistry.

Selective reactions of carbanions with p-quinones. The aggregate model

D. Liotta, M. Saindane, C. Barnum, 1981 .

2,6-Disubstituted aryl carboxylic acids, leaving groups "par excellence" for benzisothiazolone inhibitors of human leukocyte elastase.

R. Gordon, M. Saindane, D. Hlasta, 1994, Journal of medicinal chemistry.

Origins of regio- and stereoselectivity in additions of phenylselenenyl chloride to allylic alcohols and the applicability of these additions to a simple 1,3-enone transposition sequence

D. Liotta, M. Saindane, G. Zima, 1982 .

Reactions involving selenium metal as an electrophile. 2. A general procedure for the preparation of unsaturated β-dicarbonyl compounds

D. Liotta, M. Saindane, H. Ensley, 1981 .

SYNTHETIC APPLICATIONS OF 2-PHENYLSELENENYLENONES. 2. SYNTHESIS OF DIHYDROJASMONE AND CIS-JASMONE

D. Liotta, M. Saindane, C. Barnum, 1981 .

Trajectories of proton transfer reactions. Experimental determination of the magnitude of primary deuterium isotope effects for proton-transfers occuring at acute angles

D. Liotta, M. Saindane, L. Waykole, 1988 .

Simple, inexpensive procedure for the large-scale production of alkyl quinones

J. Arbiser, D. Liotta, M. Saindane, 1983 .

SELECTIVE REACTIONS OF CARBANIONS WITH P-QUINONES. THE AGGREGATE MODEL

D. Liotta, M. Saindane, C. Barnum, 1981 .

4’-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses

R. Plemper, Julien Sourimant, A. Kolykhalov, 2022, bioRxiv.

ATI-2173, a Novel Liver-Targeted Non-Chain-Terminating Nucleotide for Hepatitis B Virus Cure Regimens

K. Squires, A. Kolykhalov, Gregory R. Bluemling, 2020, Antimicrobial Agents and Chemotherapy.

Reactions involving selenium metal as an electrophile: Scope and limitations of the enolate‐selenolate transformation

D. Liotta, M. Saindane, C. Barnum, 1990 .

Reactions Involving Selenium Metal as an Electrophile: Scope and Limitations of the Enolate-Selenolate Transformation.

M. Saindane, C. Barnum, Woo-Baeg Choi, 1990 .

Rearrangement of a-Phenylselenenylketones

D. Liotta, M. Saindane, A. Fivush, 1986 .

Based-induced rearrangements of .alpha.-phenylselenenyl ketones

D. Liotta, M. Saindane, 1982 .

Reactions involving selenium metal as an electrophile. The enolate - selenolate transformation

D. Liotta, M. Saindane, C. Barnum, 1980 .

Asymmetric synthesis of host-directed inhibitors of myxoviruses

J. Ndungu, J. Snyder, P. Thepchatri, 2013, Beilstein journal of organic chemistry.

An Orally Available, Small-Molecule Polymerase Inhibitor Shows Efficacy Against a Lethal Morbillivirus Infection in a Large Animal Model

R. Plemper, D. Liotta, V. von Messling, 2014, Science Translational Medicine.

Krumm Against a Lethal Morbillivirus Infection in a Large Animal Model An Orally Available , Small-Molecule Polymerase Inhibitor Shows Efficacy

R. Plemper, D. Liotta, M. Natchus, 2014 .

SARS-CoV-2 variant of concern type and biological sex affect efficacy of molnupiravir in dwarf hamster model of severe COVID-19

R. Plemper, Julien Sourimant, R. Cox, 2022, bioRxiv.