James E. Melnyk

发表

A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing

Benjamin J. Polacco, Robyn M. Kaake, Gwendolyn M. Jang, 2020, Nature.

The Global Phosphorylation Landscape of SARS-CoV-2 Infection

Andrew R. Leach, Anna Gaulton, Aurelien Dugourd, 2020, Cell.

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

Trey Ideker, Claudia Hernandez-Armenta, Brian K. Shoichet, 2020, bioRxiv.

Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant

N. Krogan, K. Shokat, K. Obernier, 2021, bioRxiv.

The splicing modulator sulfonamide indisulam reduces AR-V7 in prostate cancer cells.

K. Shokat, B. Hann, F. Feng, 2020, Bioorganic & medicinal chemistry.

Peptidoglycan Modifications Tune the Stability and Function of the Innate Immune Receptor Nod2.

James E. Melnyk, C. Grimes, Ching‐Wen Hou, 2015, Journal of the American Chemical Society.

Targeting a splicing-mediated drug resistance mechanism in prostate cancer by inhibiting transcriptional regulation by PKCβ1

K. Shokat, B. Hann, F. Feng, 2022, Oncogene.

Pathogen- and Microbial- Associated Molecular Patterns (PAMPs/MAMPs) and the Innate Immune Response in Crohn’s Disease

James E. Melnyk, C. Grimes, Zhaoping He, 2018 .

The Innate Immune Protein Nod2 Binds Directly to MDP, a Bacterial Cell Wall Fragment

E. O’Shea, James E. Melnyk, C. Grimes, 2012, Journal of the American Chemical Society.

Membrane Association Dictates Ligand Specificity for the Innate Immune Receptor NOD2

M. Baksh, M. G. Finn, James E. Melnyk, 2017, ACS chemical biology.

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

Robyn M. Kaake, Gwendolyn M. Jang, Matthew J. O’Meara, 2020, Nature.

Crohn's Disease Variants of Nod2 Are Stabilized by the Critical Contact Region of Hsp70.

James E. Melnyk, C. Grimes, Mackenzie L Lauro, 2017, Biochemistry.