P. P. Sharp

发表

A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing

Benjamin J. Polacco, Robyn M. Kaake, Gwendolyn M. Jang, 2020, Nature.

BET bromodomain inhibitors: a patent review

P. P. Sharp, J. Garnier, C. Burns, 2014, Expert opinion on therapeutic patents.

Synthesis of a GlcNAcylated arginine building block for the solid phase synthesis of death domain glycopeptide fragments.

R. Payne, P. P. Sharp, L. Corcilius, 2017, Bioorganic & medicinal chemistry.

Signal peptide mimicry primes Sec61 for client-selective inhibition

J. Taunton, C. Kalyanaraman, J. Huiskonen, 2022, bioRxiv.

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

Trey Ideker, Claudia Hernandez-Armenta, Brian K. Shoichet, 2020, bioRxiv.

Mechanistic Studies on the Base-Promoted Conversion of Alkoxy-Substituted, Ring-Fused gem-Dihalocyclopropanes into Furans: Evidence for a Process Involving Electrocyclic Ring Closure of a Carbonyl Ylide Intermediate.

M. Coote, P. P. Sharp, Junming Ho, 2018, The Journal of organic chemistry.

Design, Synthesis, and Biological Activity of 1,2,3-Triazolobenzodiazepine BET Bromodomain Inhibitors.

M. Dawson, A. Garnham, D. Huang, 2017, ACS medicinal chemistry letters.

Evaluation of functional groups as acetyl-lysine mimetics for BET bromodomain inhibition

D. Huang, P. P. Sharp, J. Garnier, 2014 .

Simplified Silvestrol Analogues with Potent Cytotoxic Activity

David C. S. Huang, J. Chambers, J. White, 2014, ChemMedChem.

Consecutive gold(I)-catalyzed cyclization reactions of o-(buta-1,3-diyn-1-yl-)-substituted N-aryl ureas: a one-pot synthesis of pyrimido[1,6-a]indol-1(2H)-ones and related systems.

P. P. Sharp, A. Willis, M. Banwell, 2013, Organic letters.

Dichlorocarbene adducts of alkyl enol ethers as precursors to furans: application to a total synthesis of the furanosesquiterpene (±)-pallescensin A

P. P. Sharp, A. Willis, M. Banwell, 2006 .

Total Syntheses of the 3H-Pyrrolo[2,3-c]quinolone-containing Alkaloids Marinoquinolines A-F, K and Aplidiopsamine A Using a Palladium-catalysed Ullmann Cross-coupling/Reductive Cyclization Pathway.

C. Jackson, P. P. Sharp, P. Lan, 2019, The Journal of organic chemistry.

CIS is a potent checkpoint in NK cell–mediated tumor immunity

Laura F. Dagley, S. Li, W. Shi, 2016, Nature Immunology.

A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis

Erinna F. Lee, Laura F. Dagley, P. Colman, 2019, Nature Chemical Biology.

BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells

A. Chalk, A. Zannettino, M. Walia, 2015, Scientific Reports.

Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis

Priya S. Shah, Gwendolyn M. Jang, K. Pollard, 2018, Cell.

Inhibition of the Sec61 translocon overcomes cytokine‐induced glucocorticoid resistance in T‐cell acute lymphoblastic leukaemia

J. Taunton, D. Teachey, T. Ryan, 2022, British journal of haematology.

BET inhibition represses miR17-92 to drive BIM-initiated apoptosis of normal and transformed hematopoietic cells

Stefan P. Glaser, A. Strasser, P. P. Sharp, 2016, Leukemia.

A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production

J. Sandow, M. Parker, J. Holien, 2015, Nature Communications.

Inhibitors of Eukaryotic Translational Machinery as Therapeutic Agents.

P. P. Sharp, Angela Fan, 2021, Journal of medicinal chemistry.

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

Robyn M. Kaake, Gwendolyn M. Jang, Matthew J. O’Meara, 2020, Nature.