A. Bender

发表

Point-of-Care HIV Viral Load Testing: an Essential Tool for a Sustainable Global HIV/AIDS Response

P. Drain, N. Garrett, J. Posner, 2019, Clinical Microbiology Reviews.

Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use

J. Beavo, A. Bender, Andrew T. Bender, 2006, Pharmacological Reviews.

Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity

R. Walsky, J. Vlach, D. Musil, 2020, The Journal of Pharmacology and Experimental Therapeutics.

Efficacy and Pharmacodynamic Modeling of the BTK Inhibitor Evobrutinib in Autoimmune Disease Models

M. Camps, P. Schroeder, A. Bender, 2019, The Journal of Immunology.

Discovery of potent and selective reversible Bruton's tyrosine kinase inhibitors.

A. Bender, A. Goutopoulos, Xiaohua Zhu, 2021, Bioorganic & medicinal chemistry.

Ubiquitination of Neuronal Nitric-oxide Synthase in Vitro and in Vivo *

A. Bender, Andrew T. Bender, D. Demady, 2000, The Journal of Biological Chemistry.

PDE1B2 regulates cGMP and a subset of the phenotypic characteristics acquired upon macrophage differentiation from a monocyte.

J. Beavo, A. Bender, Andrew T. Bender, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Aminoguanidine-mediated Inactivation and Alteration of Neuronal Nitric-oxide Synthase*

A. Bender, S. Jianmongkol, Andrew T. Bender, 2000, The Journal of Biological Chemistry.

Elevated cyclic AMP and PDE4 inhibition induce chemokine expression in human monocyte-derived macrophages

Kimberly C. Smith, M. Gilchrist, A. Aderem, 2009, Proceedings of the National Academy of Sciences.

Differentiation of human monocytes in vitro with granulocyte-macrophage colony-stimulating factor and macrophage colony-stimulating factor produces distinct changes in cGMP phosphodiesterase expression.

J. Beavo, D. Giordano, A. Bender, 2004, Cellular signalling.

REverSe TRanscrIptase chain termination (RESTRICT) for selective measurement of nucleotide analogs used in HIV care and prevention

Alicia H Gim, Derin Sevenler, P. Drain, 2021, Bioengineering & translational medicine.

Guanabenz-mediated Inactivation and Enhanced Proteolytic Degradation of Neuronal Nitric-oxide Synthase*

A. Bender, S. Jianmongkol, Andrew T. Bender, 2000, The Journal of Biological Chemistry.

Discovery of Affinity‐Based Probes for Btk Occupancy Assays

Daigen Xu, A. Bender, A. Goutopoulos, 2019, ChemMedChem.

Btk inhibition treats TLR7/IFN driven murine lupus.

Daigen Xu, E. Samy, A. Bender, 2016, Clinical immunology.

Assembly and activation of heme-deficient neuronal NO synthase with various porphyrins.

A. Bender, Andrew T. Bender, Y. Kamada, 2002, Journal of inorganic biochemistry.

An enzymatic assay for rapid measurement of antiretroviral drug levels.

Derin Sevenler, P. Drain, J. Posner, 2020, ACS sensors.

Rapid detection of hepatitis C virus using recombinase polymerase amplification

A. Bender, L. Lillis, D. Boyle, 2022, PloS one.

Safety, Tolerability, Pharmacokinetics, Target Occupancy, and Concentration‐QT Analysis of the Novel BTK Inhibitor Evobrutinib in Healthy Volunteers

J. Laurent, A. Bender, D. Mitchell, 2019, Clinical and translational science.

Point-of-care HIV-1 diagnostic with integrated nucleic acid extraction and amplification from whole blood

J. Posner, A. Bender, D. Boyle, 2016, 2016 IEEE Healthcare Innovation Point-Of-Care Technologies Conference (HI-POCT).

TLR7 and TLR8 Differentially Activate the IRF and NF-κB Pathways in Specific Cell Types to Promote Inflammation

M. Jensen, S. Kasar, J. Vlach, 2020, ImmunoHorizons.

Agmatine enhances the NADPH oxidase activity of neuronal NO synthase and leads to oxidative inactivation of the enzyme.

A. Bender, S. Jianmongkol, Andrew T. Bender, 2001, Molecular pharmacology.

Discovery of Evobrutinib: An Oral, Potent and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases.

M. Camps, A. Follis, B. Huck, 2019, Journal of medicinal chemistry.

Ability of Bruton’s Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor Signaling

Theresa Johnson, Philipp Haselmayer, A. Bender, 2017, Molecular Pharmacology.

An enzymatic assay to measure long-term adherence to pre-exposure prophylaxis and antiretroviral therapy

Derin Sevenler, P. Drain, J. Posner, 2019, bioRxiv.

hsp90 Is Required for Heme Binding and Activation of Apo-Neuronal Nitric-oxide Synthase

W. Pratt, A. Bender, K. C. Kanelakis, 2002, The Journal of Biological Chemistry.

Quantitative Isothermal Amplification on Paper Membranes using Amplification Nucleation Site Analysis

J. Posner, A. Bender, Benjamin P. Sullivan, 2022, bioRxiv.

The ability of Btk inhibitors to sequester Y 551 and prevent phosphorylation determines potency for inhibition of FcR but not B cell receptor signaling

A. Bender, R. Grenningloh, A. Gardberg, 2016 .

Semiquantitative Nucleic Acid Test with Simultaneous Isotachophoretic Extraction and Amplification.

David S Boyle, Lorraine Lillis, Jonathan D Posner, 2018, Analytical chemistry.

Autoantibody repertoire characterization provides insight into the pathogenesis of monogenic and polygenic autoimmune diseases

M. Jensen, J. Nardone, J. Vlach, 2023, Frontiers in Immunology.

Alteration of the heme prosthetic group of neuronal nitric-oxide synthase during inactivation by N(G)-amino-L-arginine in vitro and in vivo.

A. Bender, P. Hollenberg, S. Jianmongkol, 2002, Molecular pharmacology.

Assessment of the translational value of mouse lupus models using clinically relevant biomarkers.

Yueyun Ding, A. Bender, S. Ishizaka, 2014, Translational research : the journal of laboratory and clinical medicine.

Selective up-regulation of PDE1B2 upon monocyte-to-macrophage differentiation.

J. Beavo, E. Wang, A. Bender, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Specific localized expression of cGMP PDEs in Purkinje neurons and macrophages

J. Beavo, A. Bender, Andrew T. Bender, 2004, Neurochemistry International.

HIV pre-exposure prophylaxis adherence test using reverse transcription isothermal amplification inhibition assay.

P. Drain, J. Posner, A. Bender, 2020, Analytical methods : advancing methods and applications.

Rosiglitazone Inhibits Acyl-CoA Synthetase Activity and Fatty Acid Partitioning to Diacylglycerol and Triacylglycerol via a Peroxisome Proliferator–Activated Receptor-γ–Independent Mechanism in Human Arterial Smooth Muscle Cells and Macrophages

Ashley M. Sherrid, R. Coleman, W. Hsueh, 2007, Diabetes.

Calmodulin-Stimulated Cyclic Nucleotide Phosphodiesterases

A. Bender, Andrew T. Bender, 2006 .

Rosiglitazone Inhibits Acyl-CoA Synthetase Activity and Fatty Acid Partitioning to Diacylglycerol and Triacylglycerol via a PPAR γ-Independent Mechanism in Human Arterial Smooth Muscle Cells and Macrophages

Ashley M. Sherrid, R. Coleman, W. Hsueh, 2006 .

Nucleic acid sample preparation from whole blood in a paper microfluidic device using isotachophoresis.

J. Posner, A. Bender, Benjamin P. Sullivan, 2020, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Neuronal Nitric-oxide Synthase Is Regulated by the hsp90-based Chaperone System in Vivo *

A. Silverstein, W. Pratt, A. Bender, 1999, The Journal of Biological Chemistry.

Current state of commercial point-of-care nucleic acid tests for infectious diseases.

P. Drain, J. Posner, A. Bender, 2021, The Analyst.

Heme Insertion, Assembly, and Activation of Apo-neuronal Nitric-oxide Synthase in Vitro *

A. Bender, Andrew T. Bender, M. Nakatsuka, 2000, The Journal of Biological Chemistry.

Enzymatic and chemical-based methods to inactivate endogenous blood ribonucleases for nucleic acid diagnostics.

J. Posner, A. Bender, L. Lillis, 2020, The Journal of molecular diagnostics : JMD.

HIV detection from human serum with paper-based isotachophoretic RNA extraction and reverse transcription recombinase polymerase amplification.

J. Posner, A. Bender, L. Lillis, 2021, The Analyst.

Evaluation of a candidate anti-arthritic drug using the mouse collagen antibody induced arthritis model and clinically relevant biomarkers.

T. Satoh, Yueyun Ding, A. Bender, 2013, American journal of translational research.