C. Xing

发表

A three-layer competition-based giant magnetoresistive assay for direct quantification of endoglin from human urine.

Jian-Ping Wang, Ying Jing, Jianping Wang, 2011, Analytical chemistry.

Nanomagnetic competition assay for low-abundance protein biomarker quantification in unprocessed human sera.

Jian-Ping Wang, Ying Jing, Xiaofeng Yao, 2010, Journal of the American Chemical Society.

A detection system based on giant magnetoresistive sensors and high-moment magnetic nanoparticles demonstrates zeptomole sensitivity: potential for personalized medicine.

Jian-Ping Wang, Ying Jing, Xiaofeng Yao, 2009, Angewandte Chemie.

Biomarkers identification and detection based on GMR sensor and sub 13 nm magnetic nanoparticles

Jian-Ping Wang, Ying Jing, Xiaofeng Yao, 2009, 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

Structure-activity relationship studies of chalcone leading to 3-hydroxy-4,3',4',5'-tetramethoxychalcone and its analogues as potent nuclear factor kappaB inhibitors and their anticancer activities.

B. Srinivasan, C. Xing, T. E. Johnson, 2009, Journal of medicinal chemistry.

Development of selective inhibitors for anti-apoptotic Bcl-2 proteins from BHI-1.

Y. Sham, Xiaohu Tang, C. Xing, 2007, Bioorganic & medicinal chemistry.

Structure-activity relationship and molecular mechanisms of ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4h-chromene-3-carboxylate (sha 14-1) and its analogues.

B. Srinivasan, C. Xing, S. Das, 2009, Journal of medicinal chemistry.

Structure-activity relationship studies of ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (HA 14-1), an antagonist for antiapoptotic Bcl-2 proteins to overcome drug resistance in cancer.

C. Xing, Jignesh M. Doshi, Defeng Tian, 2006, Journal of medicinal chemistry.

Inhibitor of Apoptosis Protein (IAP) Antagonists in Anticancer Agent Discovery: Current Status and Perspectives.

C. Xing, Wannian Zhang, Lijuan Xu, 2019, Journal of medicinal chemistry.

Chalcone: A Privileged Structure in Medicinal Chemistry.

C. Xing, Zhenyuan Miao, Wannian Zhang, 2017, Chemical reviews.

Reducing Chemotherapy-Induced DNA Damage via nAChR-Mediated Redox Reprograming—A New Mechanism for SCLC Chemoresistance Boosted by Nicotine

F. Kaye, Z. Huo, G. Warren, 2022, Cancers.

Chalcone-based inhibitors against hypoxia-inducible factor 1--structure activity relationship studies.

B. Srinivasan, C. Xing, T. E. Johnson, 2011, Bioorganic & medicinal chemistry letters.

Identification of methysticin as a potent and non-toxic NF-kappaB inhibitor from kava, potentially responsible for kava's chemopreventive activity.

C. Xing, David L. Hermanson, Ahmad Ali Shaik, 2009, Bioorganic & medicinal chemistry letters.

A stable isotope dilution tandem mass spectrometry method of major kavalactones and its applications

B. Avery, C. Xing, S. Eans, 2018, PloS one.

Measuring the Chemical and Cytotoxic Variability of Commercially Available Kava (Piper methysticum G. Forster)

Amanda C. Martin, C. Xing, A. Hegeman, 2014, PloS one.

Flavokawains A and B in Kava, Not Dihydromethysticin, Potentiate Acetaminophen-Induced Hepatotoxicity in C57BL/6 Mice

C. Xing, S. Narayanapillai, P. Leitzman, 2014, Chemical research in toxicology.

Identification of GAPDH as a protein target of the saframycin antiproliferative agents.

C. Xing, A. Myers, J. Barbay, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Preparation of penta-O-galloyl-β-D-glucose from tannic acid and plasma pharmacokinetic analyses by liquid-liquid extraction and reverse-phase HPLC.

Sung-Hoon Kim, J. Lü, Lei Wang, 2011, Journal of pharmaceutical and biomedical analysis.

A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy

X. Gou, Han-Ming Shen, B. Srinivasan, 2013, Oncogene.

LKB1 phosphorylation and deactivation in lung cancer by NNAL, a metabolite of tobacco-specific carcinogen, in an isomer-dependent manner

Z. Huo, R. Salloum, A. Zingone, 2022, Oncogene.

Characterization of the Fluorescence Properties of 4‐Dialkylaminochalcones and Investigation of the Cytotoxic Mechanism of Chalcones

C. Xing, Bo Zhou, Junxuan Lu, 2016, Archiv der Pharmazie.

Structure-activity relationship (SAR) study of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and the potential of the lead against multidrug resistance in cancer treatment.

C. Xing, Bo Zhou, G. Aridoss, 2012, Journal of medicinal chemistry.

Dihydromethysticin (DHM) Blocks Tobacco Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-Induced O6-Methylguanine in a Manner Independent of the Aryl Hydrocarbon Receptor (AhR) Pathway in C57BL/6 Female Mice.

C. Baglole, C. Xing, P. Upadhyaya, 2016, Chemical research in toxicology.

LKB1 phosphorylation and deactivation in lung cancer by NNAL, a metabolite of tobacco-specific carcinogen, in an isomer-dependent manner

Z. Huo, R. Salloum, A. Zingone, 2022, Oncogene.

Exploring the Structure-Activity Relationship and Mechanism of a Chromene Scaffold (CXL Series) for Its Selective Antiproliferative Activity toward Multidrug-Resistant Cancer Cells.

Haifeng Sun, C. Xing, C. Cogle, 2018, Journal of medicinal chemistry.

sHA 14-1, a stable and ROS-free antagonist against anti-apoptotic Bcl-2 proteins, bypasses drug resistances and synergizes cancer therapies in human leukemia cell.

Jun Peng, Jialing Lin, C. Xing, 2008, Cancer letters.

Crystallography-Guided Optimizations of the Keap1-Nrf2 Inhibitors on the Solvent Exposed Region: From Symmetric to Asymmetric Naphthalenesulfonamides.

Guodong Liu, C. Xing, Lijuan Xu, 2022, Journal of medicinal chemistry.

Cytochrome P450 Isoforms in the Metabolism of Decursin and Decursinol Angelate from Korean Angelica.

Cheng Jiang, J. Lü, C. Xing, 2015, The American journal of Chinese medicine.

Chemopreventive Effects of Korean Angelica versus Its Major Pyranocoumarins on Two Lineages of Transgenic Adenocarcinoma of Mouse Prostate Carcinogenesis

Sung-Hoon Kim, Cheng Jiang, J. Lü, 2015, Cancer Prevention Research.

Kava and its Kavalactones Inhibit Norepinephrine-induced Intracellular Calcium Influx in Lung Cancer Cells

C. Xing, Tengfei Bian, Jordy F. Botello, 2019, Planta Medica.

Quantitative profiling of cortisol metabolites in human urine by high-resolution accurate-mass MS.

C. Xing, N. Fujioka, Yi Wang, 2018, Bioanalysis.

Pyranocoumarin Tissue Distribution, Plasma Metabolome and Prostate Transcriptome Impacts of Sub-Chronic Exposure to Korean Angelica Supplement in Mice.

Cheng Jiang, J. Lü, C. Xing, 2016, The American journal of Chinese medicine.

Cancer Chemoprevention with Korean Angelica: Active Compounds, Pharmacokinetics, and Human Translational Considerations

Cheng Jiang, J. Lü, C. Xing, 2015, Current Pharmacology Reports.

Structure-activity relationship and molecular mechanisms of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and its analogues.

W. T. Beck, B. Srinivasan, C. Xing, 2011, Journal of medicinal chemistry.

Ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017): a novel scaffold that resensitizes multidrug resistant leukemia cells to chemotherapy.

Yunfang Li, C. Xing, A. Kelekar, 2013, ACS chemical biology.

Design, synthesis, and enzymatic characterization of quinazoline-based CYP1A2 inhibitors.

C. Xing, Jordy F. Botello, Pedro Corral, 2019, Bioorganic & medicinal chemistry letters.

CXL146, a Novel 4H-Chromene Derivative, Targets GRP78 to Selectively Eliminate Multidrug-Resistant Cancer Cells

C. Vulpe, C. Xing, A. Tagmount, 2020, Molecular Pharmacology.

4H-Chromene-based anticancer agents towards multi-drug resistant HL60/MX2 human leukemia: SAR at the 4th and 6th positions.

C. Xing, Bo Zhou, G. Aridoss, 2016, Bioorganic & medicinal chemistry.

Ethyl-2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H- chromene-3-carboxylate (HA 14-1), a prototype small-molecule antagonist against antiapoptotic Bcl-2 proteins, decomposes to generate reactive oxygen species that induce apoptosis.

C. Xing, Jignesh M. Doshi, Defeng Tian, 2007, Molecular pharmaceutics.

Inhibition of siderophore biosynthesis by 2-triazole substituted analogues of 5'-O-[N-(salicyl)sulfamoyl]adenosine: antibacterial nucleosides effective against Mycobacterium tuberculosis.

Courtney C Aldrich, C. Xing, C. Aldrich, 2008, Journal of medicinal chemistry.

Diverse Molecular Targets for Chalcones with Varied Bioactivities

C. Xing, Bo Zhou, Chengguo Xing, 2015, Medicinal chemistry.