P. Sims

发表

Phanerochaete chrysosporium and its natural substrate.

P. Birch, J. Copa-Patiño, P. Broda, 1994, FEMS microbiology reviews.

A mutation-specific PCR system to detect sequence variation in the dihydropteroate synthetase gene of Plasmodium falciparum.

J. E. Hyde, P. Sims, D. Brooks, 1995, Molecular and biochemical parasitology.

The identification, molecular cloning and characterisation of a gene from Phanerochaete chrysosporium that shows strong homology to the exo-cellobiohydrolase I gene from Trichoderma reesei.

P. Broda, P. Sims, C. James, 1988, Gene.

Identification of Asp-130 as the catalytic nucleophile in the main alpha-galactosidase from Phanerochaete chrysosporium, a family 27 glycosyl hydrolase.

S. Withers, H. Brumer, M. Sinnott, 2000, Biochemistry.

Green roots of malaria.

P. Sims, J. Hyde, M. Read, 1994, Parasitology today.

Functional expression of the dihydrofolate reductase and thymidylate synthetase activities of the human malaria parasite Plasmodium falciparum in Escherichia coli.

P. Sims, S. Hall, J. Hyde, 1991, Molecular and biochemical parasitology.

Lignocellulose degradation by Phanerochaete chrysosporium: purification and characterization of the main alpha-galactosidase.

H. Brumer, M. Sinnott, P. Sims, 1999, The Biochemical journal.

Lignin biodegradation: a molecular biological approach.

P. Broda, P. Sims, J. Mason, 1989, Essays in biochemistry.

A bifunctional dihydrofolate synthetase--folylpolyglutamate synthetase in Plasmodium falciparum identified by functional complementation in yeast and bacteria.

J. E. Hyde, C. Plowe, P. Sims, 2001, Molecular and biochemical parasitology.

Definition of the substrate specificity of the 'sensing' xylanase of Streptomyces cyaneus using xylooligosaccharide and cellooligosaccharide glycosides of 3,4-dinitrophenol.

M. Sinnott, P. Sims, C. Chany, 1997, Journal of biotechnology.

Development and comparison of quantitative assays for the dihydropteroate synthetase codon 540 mutation associated with sulfadoxine resistance in Plasmodium falciparum

P. Sims, J. Hyde, C. S. Lee, 1998, Parasitology.

On ;the efficacy of antifolate antimalarial combinations in Africa'.

P. Sims, J. Hyde, P. Wang, 1998, Parasitology today.

Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins.

J. E. Hyde, O. Doumbo, M. Tanner, 1997, Molecular and biochemical parasitology.

Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine.

J. E. Hyde, P. Sims, D. Brooks, 1994, European journal of biochemistry.

Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next?

J. E. Hyde, J. Kublin, A. Cowman, 2001, Trends in parasitology.

Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization

J. E. Hyde, P. Sims, J. Hyde, 1997, Molecular microbiology.

Selection and synergy in Plasmodium falciparum.

P. Sims, J. Hyde, P. Wang, 1999, Parasitology today.

A modified in vitro sulfadoxine susceptibility assay for Plasmodium falciparum suitable for investigating Fansidar resistance

J. E. Hyde, P. Sims, J. Hyde, 1997, Parasitology.

Characterisation of the dihydrofolate reductase-thymidylate synthetase gene from human malaria parasites highly resistant to pyrimethamine.

P. Sims, J. Hyde, V. A. Snewin, 1989, Gene.

Characterisation of the gene encoding an unusually divergent TATA-binding protein (TBP) from the extremely A+T-rich human malaria parasite Plasmodium falciparum.

J. E. Hyde, P. Sims, M Read, 1993, Gene.

Anomalous dinucleotide frequencies in both coding and non-coding regions from the genome of the human malaria parasite Plasmodium falciparum.

J. E. Hyde, P. Sims, J. Hyde, 1987, Gene.

Molecular characterisation of the enolase gene from the human malaria parasite Plasmodium falciparum. Evidence for ancestry within a photosynthetic lineage.

Kevin E. Hicks, J. E. Hyde, P. Sims, 1994, European journal of biochemistry.

Glycolytic pathway of the human malaria parasite Plasmodium falciparum: primary sequence analysis of the gene encoding 3-phosphoglycerate kinase and chromosomal mapping studies.

J. E. Hyde, S. Holloway, P. Sims, 1991, Gene.

Characterization of three genes encoding enzymes of the folate biosynthetic pathway in Plasmodium falciparum

J. E. Hyde, P. Sims, J. Hyde, 2001, Parasitology.

A general approach to isolating Plasmodium falciparum genes using non-redundant oligonucleotides inferred from protein sequences of other organisms.

S. Kelly, S. Holloway, P. Sims, 1989, Molecular and biochemical parasitology.

The tubulin genes of the human malaria parasite Plasmodium falciparum, their chromosomal location and sequence analysis of the alpha-tubulin II gene.

J. E. Hyde, S. Holloway, P. Sims, 1990, Molecular and biochemical parasitology.

Isolation and molecular characterization of the bifunctional hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase gene from Toxoplasma gondii.

J. E. Hyde, P. Sims, C. Delves, 1997, Molecular and biochemical parasitology.

Isolation of alpha-tubulin genes from the human malaria parasite, Plasmodium falciparum: sequence analysis of alpha-tubulin.

J. E. Hyde, S. Holloway, P. Sims, 1989, Molecular microbiology.