H. Qadota

发表

Bni1p implicated in cytoskeletal control is a putative target of Rho1p small GTP binding protein in Saccharomyces cerevisiae.

T Watanabe, K Tanaka, Y. Ohya, 1996, The EMBO journal.

Identification of Yeast Rho1p GTPase as a Regulatory Subunit of 1,3-β-Glucan Synthase

T Watanabe, Y. Anraku, D. E. Levin, 1996, Science.

Multiple Functional Domains of the Yeast l,3-β-Glucan Synthase Subunit Fks1p Revealed by Quantitative Phenotypic Analysis of Temperature-Sensitive Mutants

Y. Ohya, Hiroki Okada, A. Hirata, 2010, Genetics.

Twitchin kinase inhibits muscle activity

O. Mayans, Hang Lu, Hyundoo Hwang, 2017, Molecular biology of the cell.

UNC-45 has a crucial role in maintaining muscle sarcomeres during aging in Caenorhabditis elegans

A. Oberhauser, A. Bailey, H. Qadota, 2022, bioRxiv.

Phosphatidylinositol-4-phosphate 5-Kinase Localized on the Plasma Membrane Is Essential for Yeast Cell Morphogenesis*

Y. Anraku, Y. Ohya, Keiichi Homma, 1998, The Journal of Biological Chemistry.

Complementing Yeast rho1 Mutation Groups with Distinct Functional Defects*

Y. Ohya, H. Okano, A. Mino, 2001, The Journal of Biological Chemistry.

RHO gene products, putative small GTP‐binding proteins, are importnat for activation of the CAL1/CDC43 gene product, a protein geranylgeranyltransferase in Saccharomyces cerevisiae

Y. Anraku, A. Fujiyama, Y. Ohya, 1992, Yeast.

Signaling toward yeast 1,3-beta-glucan synthesis.

Y. Anraku, Y. Ohya, T. Watanabe, 1996, Cell structure and function.

The Rho GAP RRC-1 is a member of the PIX pathway and controls assembly or stability of integrin adhesion complexes in muscle

H. Qadota, G. Benian, Jasmine C. Moody, 2022 .

Immunofluorescent localization of proteins in Caenorhabditis elegans muscle.

H. Qadota, G. Benian, Kristy J. Wilson, 2012, Methods in molecular biology.

ROM7/BEM4 encodes a novel protein that interacts with the Rho1p small GTP-binding protein in Saccharomyces cerevisiae

Y. Ohya, T. Watanabe, K. Tanaka, 1996, Molecular and cellular biology.

Conditional lethality of a yeast strain expressing human RHOA in place of RHO1.

D. Botstein, Y. Anraku, Y. Ohya, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Suppression of yeast geranylgeranyl transferase I defect by alternative prenylation of two target GTPases, Rho1p and Cdc42p.

D. Botstein, Y. Anraku, Y. Ohya, 1993, Molecular biology of the cell.

Phytosphingosine Localized to the Endoplasmic Reticulum

Y. Ohya, Y. Seyama, I. Nishida, 2001 .

Prenylation of Rho1p is required for activation of yeast 1, 3-beta-glucan synthase.

Y. Ohya, T. Watanabe, M. Arisawa, 1999, The Journal of biological chemistry.

A LIM-9 (FHL)/SCPL-1 (SCP) complex interacts with the C-terminal protein kinase regions of UNC-89 (obscurin) in Caenorhabditis elegans muscle.

A. Oberhauser, H. Qadota, G. Benian, 2009, Journal of molecular biology.

Extensive and modular intrinsically disordered segments in C. elegans TTN-1 and implications in filament binding, elasticity and oblique striation.

H. Qadota, Kuan Wang, D. Flaherty, 2010, Journal of molecular biology.

Activation of Yeast Protein Kinase C by Rho1 GTPase (*)

Y. Anraku, D. E. Levin, Y. Ohya, 1996, The Journal of Biological Chemistry.

α-actinin is required for the proper assembly of Z-disk/focal-adhesion-like structures and for efficient locomotion in Caenorhabditis elegans.

Jeffrey N. Stirman, Hang Lu, G. Moulder, 2010, Journal of molecular biology.

UNC-89 (obscurin) binds to MEL-26, a BTB-domain protein, and affects the function of MEI-1 (katanin) in striated muscle of Caenorhabditis elegans

H. Qadota, P. Mains, G. Benian, 2012, Molecular biology of the cell.

The DH-PH region of the giant protein UNC-89 activates RHO-1 GTPase in Caenorhabditis elegans body wall muscle.

H. Qadota, A. Blangy, G. Benian, 2008, Journal of molecular biology.

The Caenorhabditis elegans paxillin orthologue, PXL-1, is required for pharyngeal muscle contraction and for viability

D. Moerman, A. Warner, H. Qadota, 2011, Molecular biology of the cell.

A novel protein phosphatase is a binding partner for the protein kinase domains of UNC-89 (Obscurin) in Caenorhabditis elegans.

H. Qadota, T. Stark, G. Benian, 2008, Molecular biology of the cell.

UNC-98 links an integrin-associated complex to thick filaments in Caenorhabditis elegans muscle

H. Qadota, G. Benian, M. Landsverk, 2006, The Journal of cell biology.

C . elegans UNC-98 , a C 2 H 2 Zn finger protein , is a novel partner of UNC-97 / PINCH in muscle adhesion complexes

D. Moerman, H. Qadota, D. Flaherty, 2003 .

The GEX-2 and GEX-3 proteins are required for tissue morphogenesis and cell migrations in C. elegans.

C. Mello, K. Kaibuchi, M. Soto, 2002, Genes & development.

morphogenesis and cell migrations in C . elegans The GEX-2 and GEX-3 proteins are required for tissue

C. Mello, K. Kaibuchi, M. Soto, 2002 .

ZYX-1, the unique zyxin protein of Caenorhabditis elegans, is involved in dystrophin-dependent muscle degeneration

Nicolas C. Rochette, L. Ségalat, H. Qadota, 2013, Molecular biology of the cell.

Neuronal C/EBPβ/AEP pathway shortens life span via selective GABAnergic neuronal degeneration by FOXO repression

S. Yu, K. Ye, Xia Liu, 2022, Science advances.

CPNA-1, a copine domain protein, is located at integrin adhesion sites and is required for myofilament stability in Caenorhabditis elegans

D. Moerman, T. Rogalski, A. Warner, 2013, Molecular biology of the cell.

Molecular cloning and characterization of Drosophila genes encoding small GTPases of the rab and rho families

Y. Ohya, Y. Hotta, H. Qadota, 1997, Molecular and General Genetics MGG.

CSN-5, a component of the COP9 signalosome complex, regulates the levels of UNC-96 and UNC-98, two components of M-lines in Caenorhabditis elegans muscle.

H. Qadota, T. Stark, G. Benian, 2009, Molecular biology of the cell.

UNC-98 and UNC-96 interact with paramyosin to promote its incorporation into thick filaments of Caenorhabditis elegans.

K. Gernert, H. Qadota, G. Benian, 2008, Molecular biology of the cell.

Caenorhabditis elegans UNC-96 is a new component of M-lines that interacts with UNC-98 and paramyosin and is required in adult muscle for assembly and/or maintenance of thick filaments.

Seema Sheth, H. Qadota, G. Benian, 2006, Molecular biology of the cell.

Caenorhabditis elegans UNC-98, a C2H2 Zn finger protein, is a novel partner of UNC-97/PINCH in muscle adhesion complexes.

D. Moerman, H. Qadota, D. Flaherty, 2003, Molecular biology of the cell.

UNC-97 / PINCH in muscle adhesion complexes

D. Moerman, H. Qadota, D. Flaherty, 2003 .

The C. elegans eyes absent ortholog EYA-1 is required for tissue differentiation and plays partially redundant roles with PAX-6.

A. Chisholm, H. Qadota, A. Sugimoto, 2005, Developmental biology.

C. elegans PAT-4/ILK Functions as an Adaptor Protein within Integrin Adhesion Complexes

D. Moerman, H. Qadota, B. D. Williams, 2002, Current Biology.

Development, Structure, and Maintenance of C. Elegans Body Wall Muscle *

H. Qadota, G. Benian, K. Gieseler, 2022 .

Yeast 1,3-β-Glucan Synthase Activity Is Inhibited by Phytosphingosine Localized to the Endoplasmic Reticulum*

Y. Ohya, Y. Seyama, I. Nishida, 2001, The Journal of Biological Chemistry.

Ultra-structural time-course study in the C. elegans model for Duchenne muscular dystrophy highlights a crucial role for sarcomere-anchoring structures and sarcolemma integrity in the earliest steps of the muscle degeneration process.

M. Labouesse, H. Qadota, M. Mariol, 2015, Human molecular genetics.

Suppressor Mutations Suggest a Surface on PAT-4 (Integrin-linked Kinase) That Interacts with UNC-112 (Kindlin)*

K. Gernert, H. Qadota, G. Benian, 2014, The Journal of Biological Chemistry.

A Molecular Mechanism for the Requirement of PAT-4 (Integrin-linked Kinase (ILK)) for the Localization of UNC-112 (Kindlin) to Integrin Adhesion Sites*

D. Moerman, H. Qadota, G. Benian, 2012, The Journal of Biological Chemistry.

Two LIM domain proteins and UNC-96 link UNC-97/pinch to myosin thick filaments in Caenorhabditis elegans muscle.

K. Kaibuchi, H. Qadota, G. Benian, 2007, Molecular biology of the cell.

UNC-97/PINCH is involved in the assembly of integrin cell adhesion complexes in Caenorhabditis elegans body wall muscle.

D. Moerman, H. Qadota, Kenneth R Norman, 2007, Developmental biology.

Regulatory machinery of UNC‐33 Ce‐CRMP localization in neurites during neuronal development in Caenorhabditis elegans

K. Kaibuchi, M. Amano, H. Qadota, 2005, Journal of neurochemistry.

Identification of a novel Cdc42 GEF that is localized to the PAT-3-mediated adhesive structure.

D. Moerman, K. Kaibuchi, H. Qadota, 2005, Biochemical and biophysical research communications.

Isolation of the interacting molecules with GEX-3 by a novel functional screening.

Kozo Kaibuchi, K. Kaibuchi, M. Amano, 2002, Biochemical and biophysical research communications.

Indoles from commensal bacteria extend healthspan

D. Kalman, H. Qadota, Anusmita Sahoo, 2017, Proceedings of the National Academy of Sciences.

Prenylation of Rho1p Is Required for Activation of Yeast 1,3-β-Glucan Synthase*

Y. Ohya, M. Arisawa, S. B. Inoue, 1999, The Journal of Biological Chemistry.

High‐resolution imaging of muscle attachment structures in Caenorhabditis elegans

D. Hall, K. Nguyen, H. Qadota, 2017, Cytoskeleton.

Caenorhabditis elegans SORB-1 localizes to integrin adhesion sites and is required for organization of sarcomeres and mitochondria in myocytes

J. Hardin, H. Qadota, G. Benian, 2017, Molecular biology of the cell.

Mutational analysis of theβ-subunit of yeast geranylgeranyl transferase I

Y. Anraku, Y. Ohya, J. Pringle, 1996, Molecular and General Genetics MGG.

An approach for exploring interaction between two proteins in vivo

H. Qadota, G. Benian, 2013, Front. Physiol..

Lack of GTP-bound Rho1p in secretory vesicles of Saccharomyces cerevisiae

Yoshikazu Ohya, Mitsuhiro Abe, Y. Ohya, 2003, The Journal of cell biology.

Establishment of a tissue-specific RNAi system in C. elegans.

D. Moerman, K. Kaibuchi, M. Amano, 2007, Gene.

Genetic analysis suggests a surface of PAT-4 (ILK) that interacts with UNC-112 (kindlin)

A. Oberhauser, H. Qadota, G. Benian, 2022, bioRxiv.

Investigating the correlation of muscle function tests and sarcomere organization in C. elegans

S. Vanapalli, N. Szewczyk, H. Qadota, 2021, bioRxiv.

Molecular Structure of Sarcomere-to-Membrane Attachment at M-Lines in C. elegans Muscle

H. Qadota, G. Benian, 2010, Journal of biomedicine & biotechnology.

C. elegans PAT-6/Actopaxin Plays a Critical Role in the Assembly of Integrin Adhesion Complexes In Vivo

D. Moerman, H. Qadota, B. D. Williams, 2003, Current Biology.

PKN-1, a homologue of mammalian PKN, is involved in the regulation of muscle contraction and force transmission in C. elegans.

Jeffrey N. Stirman, K. Kaibuchi, M. Amano, 2011, Journal of molecular biology.

Mutations in conserved residues of the myosin chaperone UNC-45 result in both reduced stability and chaperoning activity

A. Oberhauser, John Miller, H. Qadota, 2021, bioRxiv.

Conformational changes in twitchin kinase in vivo revealed by FRET imaging of freely moving C. elegans

Daniel A. Porto, O. Mayans, Hang Lu, 2021, bioRxiv.

The Rho GAP RRC-1 is required for the assembly or stability of integrin adhesion complexes and is a member of the PIX pathway in muscle

H. Qadota, G. Benian, Jasmine C. Moody, 2023, bioRxiv.

The Rho-GEF PIX-1 directs assembly or stability of lateral attachment structures between muscle cells

E. Ortlund, C. Okafor, H. Qadota, 2020, Nature Communications.

Protein phosphatase 2A is crucial for sarcomere organization in Caenorhabditis elegans striated muscle

D. Pallas, H. Qadota, M. Srayko, 2018, Molecular biology of the cell.

The SH3 domain of UNC-89 (obscurin) interacts with paramyosin, a coiled-coil protein, in Caenorhabditis elegans muscle

Jonathan L. McMurry, O. Mayans, J. McMurry, 2016, Molecular biology of the cell.

Twitchin kinase interacts with MAPKAP kinase 2 in Caenorhabditis elegans striated muscle

H. Qadota, G. Benian, Yohei Matsunaga, 2015, Molecular biology of the cell.

Bending amplitude - a new quantitative assay of C. elegans locomotion: identification of phenotypes for mutants in genes encoding muscle focal adhesion components.

Hang Lu, Jeffrey N. Stirman, Hang Lu, 2012, Methods.

Missense mutation of a conserved residue in UNC-112 (kindlin) eliminates binding to PAT-4 (ILK)

A. Oberhauser, H. Qadota, G. Benian, 2021, microPublication biology.

Genetic analysis of the interaction between the N- and C-terminal halves of UNC-112 (kindlin)

A. Oberhauser, H. Qadota, G. Benian, 2020, microPublication biology.

A Region of UNC-89 (Obscurin) Lying between Two Protein Kinase Domains Is a Highly Elastic Spring Required for Proper Sarcomere Organization.

A. Oberhauser, S. Vanapalli, H. Qadota, 2020, Journal of molecular biology.

A Region of UNC-89 (obscurin) Lying Between Two Protein Kinase Domains is a Highly Elastic Spring Required for Proper Sarcomere Assembly

A. Oberhauser, S. Vanapalli, H. Qadota, 2020, bioRxiv.

Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase

Klaus Schulten, Dmitri I Svergun, Olga Mayans, 2012, Proceedings of the National Academy of Sciences.

Geranylgeranyltransferase in Saccharornyces cerevisiae

A. Fujiyama, H. Qadota, I. Ishii, 2003 .

Mutational analysis of the structure and function of the chaperone domain of UNC-45B

A. Oberhauser, H. Qadota, G. Benian, 2020, bioRxiv.

Caenorhabditis elegans

H. Qadota, T. Stark, G. Benian, 2002 .

Extensive and modular intrinsically disordered segments in C. elegans TTN-1 and implications in filament binding, elasticity and oblique striation.

H. Qadota, Kuan Wang, D. Flaherty, 2010, Journal of molecular biology.

Diapause is associated with a change in the polarity of secretion of insulin-like peptides

H. Qadota, Takashi Iwasaki, T. Kawano, 2016, Nature Communications.