J. Konopka

发表

Iqg1p links spatial and secretion landmarks to polarity and cytokinesis

Richard A. Cerione, R. Cerione, Mahasin A. Osman, 2002, The Journal of cell biology.

The Sur7 protein resides in punctate membrane subdomains and mediates spatial regulation of cell wall synthesis in Candida albicans

J. Konopka, F. J. Alvarez, Lois M. Douglas, 2009, Communicative & integrative biology.

N-Acetylglucosamine Regulates Morphogenesis and Virulence Pathways in Fungi

J. Konopka, Kyunghun Min, Shamoon Naseem, 2019, Journal of fungi.

Pheromone Receptors (Yeast)

J. Konopka, 2004 .

A Microdomain Formed by the Extracellular Ends of the Transmembrane Domains Promotes Activation of the G Protein-Coupled α-Factor Receptor

J. Konopka, Jennifer C. Lin, James B. Konopka, 2004, Molecular and Cellular Biology.

Functional analysis of the interaction between Afr1p and the Cdc12p septin, two proteins involved in pheromone-induced morphogenesis.

L. Giot, J. Konopka, 1997, Molecular biology of the cell.

Conjugation in Saccharomyces cerevisiae.

F. Cross, L. Hartwell, J. Konopka, 1988, Annual review of cell biology.

Protection from Systemic Candida albicans Infection by Inactivation of the Sts Phosphatases

J. Konopka, Shamoon Naseem, D. Frank, 2014, Infection and Immunity.

Cell lines and clinical isolates derived from Ph1-positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration.

O. Witte, J. Singer, S. Collins, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Successful expression of a functional yeast G-protein-coupled receptor (Ste2) in mammalian cells.

E. Shumay, S. Gavi, Hsien-yu Wang, 2005, Biochemical and biophysical research communications.

An N-acetylglucosamine transporter required for arbuscular mycorrhizal symbioses in rice and maize

U. Paszkowski, C. Gutjahr, T. Brutnell, 2017, Nature Plants.

Erratum for Mor et al., “Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids”

Patrick Flaherty, G. Giaever, Xuewen Pan, 2018, mBio.

Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids

Patrick Flaherty, G. Giaever, Xuewen Pan, 2015, mBio.

Activation of the abl oncogene in murine and human leukemias.

O. Witte, J. Konopka, Owen N. Witte, 1985, Biochimica et biophysica acta.

Expression of a translocated c-abl gene in hybrids of mouse fibroblasts and chronic myelogenous leukaemia cells

O. Witte, L. Showe, J. Konopka, 1986, Nature.

Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products

O. Witte, J. Konopka, 1985, Molecular and cellular biology.

Only site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity

R. Davis, N. Rosenberg, O. Witte, 1984, Journal of virology.

Comparison of Experimental Approaches Used to Determine the Structure and Function of the Class D G Protein-Coupled Yeast α-Factor Receptor

M. Dumont, J. Konopka, 2022, Biomolecules.

Activation of the c-abl oncogene by viral transduction or chromosomal translocation generates altered c-abl proteins with similar in vitro kinase properties

R. Davis, O. Witte, J. Konopka, 1985, Molecular and cellular biology.

Sur7 Promotes Plasma Membrane Organization and Is Needed for Resistance to Stressful Conditions and to the Invasive Growth and Virulence of Candida albicans

J. Konopka, Lois M. Douglas, N. Dean, 2011, mBio.

The mitochondrial protein Mcu1 plays important roles in carbon source utilization, filamentation, and virulence in Candida albicans.

Guanghua Huang, J. Konopka, Guobo Guan, 2015, Fungal genetics and biology : FG & B.

Hyphal growth in Candida albicans does not require induction of hyphal-specific gene expression

J. Konopka, Shamoon Naseem, Esteban Araya, 2015, Molecular biology of the cell.

Candida albicans Septin Mutants Are Defective for Invasive Growth and Virulence

J. Becker, J. Konopka, S. Kauffman, 2003, Infection and Immunity.

Fungal Pathogens: Shape-Shifting Invaders.

A. Neiman, J. Konopka, Kyunghun Min, 2020, Trends in microbiology.

Regulation of the G-protein-coupled alpha-factor pheromone receptor by phosphorylation

Q. Chen, J. Konopka, Qijun Chen, 1996, Molecular and cellular biology.

Candida albicans Agar Invasion Assays.

J. Konopka, Lois M. Douglas, Shamoon Naseem, 2020, Bio-protocol.

The MARVEL Domain Protein Nce102 Regulates Actin Organization and Invasive Growth of Candida albicans

J. Konopka, Lois M. Douglas, Hong X. Wang, 2013, mBio.

N-Acetylglucosamine (GlcNAc) Induction of Hyphal Morphogenesis and Transcriptional Responses in Candida albicans Are Not Dependent on Its Metabolism*

A. Gunasekera, J. Konopka, Shamoon Naseem, 2011, The Journal of Biological Chemistry.

Identification of GIG1, a GlcNAc-Induced Gene in Candida albicans Needed for Normal Sensitivity to the Chitin Synthase Inhibitor Nikkomycin Z

Adam P. Rosebrock, A. Gunasekera, J. Konopka, 2010, Eukaryotic Cell.

Candida albicans rvs161Δ and rvs167Δ Endocytosis Mutants Are Defective in Invasion into the Oral Cavity

J. Konopka, Lois M. Douglas, Shamoon Naseem, 2019, mBio.

cAMP‐independent signal pathways stimulate hyphal morphogenesis in Candida albicans

J. Konopka, Haoyu Si, Shamoon Naseem, 2017, Molecular microbiology.

Flavodoxin-Like Proteins Protect Candida albicans from Oxidative Stress and Promote Virulence

J. Konopka, Sahil Sharma, Shamoon Naseem, 2015, PLoS pathogens.

Differential Roles of a Family of Flavodoxin-Like Proteins That Promote Resistance to Quinone-Mediated Oxidative Stress in Candida albicans

J. Konopka, Jenna E. Foderaro, 2021, Infection and Immunity.

A Candida albicans Temperature-Sensitive cdc12-6 Mutant Identifies Roles for Septins in Selection of Sites of Germ Tube Formation and Hyphal Morphogenesis

J. Konopka, Chengda Zhang, Chengda Zhang, 2012, Eukaryotic Cell.

Strategies for isolating constitutively active and dominant-negative pheromone receptor mutants in yeast.

J. Konopka, M. Dosil, 2010, Methods in enzymology.

BAR Domain Proteins Rvs161 and Rvs167 Contribute to Candida albicans Endocytosis, Morphogenesis, and Virulence

J. Konopka, Lois M. Douglas, Stephen W. Martin, 2009, Infection and Immunity.

Accessibility of cysteine residues substituted into the cytoplasmic regions of the alpha-factor receptor identifies the intracellular residues that are available for G protein interaction.

J. Konopka, Yunsook Choi, 2006, Biochemistry.

Cell Cycle Dynamics and Quorum Sensing in Candida albicans Chlamydospores Are Distinct from Budding and Hyphal Growth

J. Konopka, Lois M. Douglas, Stephen W. Martin, 2005, Eukaryotic Cell.

Comparison of class A and D G protein-coupled receptors: common features in structure and activation.

V. Hornak, M. Eilers, Steven O. Smith, 2005, Biochemistry.

N-acetylglucosamine Regulates Virulence Properties in Microbial Pathogens

J. Konopka, Shamoon Naseem, 2015, PLoS pathogens.

Phagocytes from Mice Lacking the Sts Phosphatases Have an Enhanced Antifungal Response to Candida albicans

J. Konopka, G. Russo, Kaustubh Parashar, 2018, mBio.

SUMO Modification of Septin-interacting Proteins in Candida albicans*

J. Konopka, Stephen W. Martin, 2004, Journal of Biological Chemistry.

N-Acetylglucosamine Metabolism Promotes Survival of Candida albicans in the Phagosome

M. Lorenz, J. Konopka, Robert B Williams, 2017, mSphere.

AFR1 acts in conjunction with the alpha-factor receptor to promote morphogenesis and adaptation

J. Konopka, 1993, Molecular and cellular biology.

Functional assays for mammalian G-protein-coupled receptors in yeast.

J. Konopka, M. Dosil, P. E. Mentesana, 2002, Methods in enzymology.

Aromatic residues at the extracellular ends of transmembrane domains 5 and 6 promote ligand activation of the G protein-coupled alpha-factor receptor.

W. Parrish, M. Eilers, Steven O. Smith, 2003, Biochemistry.

Two New S‐Phase‐Specific Genes from Saccharomyces cerevisiae

R. Sternglanz, J. Konopka, C. Davis, 1997, Yeast.

Fungal membrane organization: the eisosome concept.

J. Konopka, L. Douglas, 2014, Annual review of microbiology.

N-acetylglucosamine (GlcNAc) Triggers a Rapid, Temperature-Responsive Morphogenetic Program in Thermally Dimorphic Fungi

J. Konopka, Sarah A. Gilmore, A. Sil, 2013, PLoS genetics.

MCC/Eisosomes Regulate Cell Wall Synthesis and Stress Responses in Fungi

J. Konopka, Jenna E. Foderaro, L. Douglas, 2017, Journal of fungi.

Plasma membrane organization promotes virulence of the human fungal pathogen Candida albicans

J. Konopka, L. Douglas, 2016, Journal of Microbiology.

Membrane Compartment Occupied by Can1 (MCC) and Eisosome Subdomains of the Fungal Plasma Membrane

J. Konopka, Hong X. Wang, Lifang Li, 2011, Membranes.

N-Acetylglucosamine Functions in Cell Signaling

J. Konopka, 2012, Scientifica.

Novel roles for GlcNAc in cell signaling

J. Konopka, Shamoon Naseem, Salvatore M. Parrino, 2012, Communicative & integrative biology.

Distinct roles of cell wall biogenesis in yeast morphogenesis as revealed by multivariate analysis of high-dimensional morphometric data

Shinsuke Ohnuki, Yoshikazu Ohya, Y. Ohya, 2014, Molecular biology of the cell.

Sterol-Rich Plasma Membrane Domains in Fungi

J. Konopka, F. J. Alvarez, L. Douglas, 2007, Eukaryotic Cell.

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity

Susan M. Watanabe, O. Witte, J. Konopka, 1984, Cell.

Functional expression of mammalian receptors and membrane channels in different cells.

A. Lüthi, A. Engel, T. Egan, 2007, Journal of structural biology.

Lipid Raft Polarization Contributes to Hyphal Growth in Candida albicans

J. Konopka, Stephen W. Martin, 2004, Eukaryotic Cell.

S. cerevisiae α pheromone receptors activate a novel signal transduction pathway for mating partner discrimination

L. Hartwell, C. L. Jackson, J. Konopka, 1991, Cell.

Septin function in Candida albicans morphogenesis.

J. Konopka, Amy J Warenda, 2002, Molecular biology of the cell.

Raft-like membrane domains in pathogenic microorganisms.

M. Del Poeta, A. Farnoud, E. London, 2015, Current topics in membranes.

Identification of an N-acetylglucosamine transporter that mediates hyphal induction in Candida albicans.

J. Konopka, F. J. Álvarez, 2007, Molecular biology of the cell.

The C-terminus of the S. cerevisiae α-pheromone receptor mediates an adaptive response to pheromone

L. Hartwell, J. Konopka, D. Jenness, 1988, Cell.

Pathogenic Effects of IFIT2 and Interferon-β during Fatal Systemic Candida albicans Infection

N. Reich, D. Baker, J. Konopka, 2018, mBio.

Modulating Host Signaling Pathways to Promote Resistance to Infection by Candida albicans

J. Konopka, Shamoon Naseem, James B. Konopka, 2017, Front. Cell. Infect. Microbiol..

Monoclonal antibodies specific for v-abl- and c-abl-encoded molecules

N. Rosenberg, O. Witte, J. Konopka, 1986, Journal of virology.

Integrative multi-omics profiling reveals cAMP-independent mechanisms regulating hyphal morphogenesis in Candida albicans

K. Veeramah, J. Haley, J. Konopka, 2021, bioRxiv.

The pheromone signal pathway inSaccharomyces cerevisiae

S. Fields, J. Konopka, 1992, Antonie van Leeuwenhoek.

Plasma Membrane MCC/Eisosome Domains Promote Stress Resistance in Fungi

J. Konopka, Jenna E. Foderaro, Rafael M. Gandra, 2020, Microbiology and Molecular Biology Reviews.

One Health: Fungal Pathogens of Humans, Animals, and Plants

J. Heitman, A. Casadevall, L. Cowen, 2019 .

The cytoplasmic end of transmembrane domain 3 regulates the activity of the Saccharomyces cerevisiae G-protein-coupled alpha-factor receptor.

W. Parrish, M. Eilers, J. Konopka, 2002, Genetics.

Identification of a Polar Region in Transmembrane Domain 6 That Regulates the Function of the G Protein-Coupled α-Factor Receptor

J. Konopka, James B. Konopka, Peter Dube, 1998, Molecular and Cellular Biology.

Mutation of Pro-258 in transmembrane domain 6 constitutively activates the G protein-coupled alpha-factor receptor.

J. Konopka, P. Dube, S. Margarit, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Variable expression of the translocated c-abl oncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patients.

O. Witte, J. Konopka, A. Strife, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Plasma membrane architecture protects Candida albicans from killing by copper

J. Konopka, L. Douglas, 2019, PLoS genetics.

A Conserved Machinery Underlies the Synthesis of a Chitosan Layer in the Candida Chlamydospore Cell Wall

A. Neiman, J. Konopka, Kyunghun Min, 2021, mSphere.

Plasma membrane organization promotes virulence of the human fungal pathogen Candida albicans

J. Konopka, L. Douglas, 2016, Journal of Microbiology.

Microdomain Protein Nce102 Is a Local Sensor of Plasma Membrane Sphingolipid Balance

M. Del Poeta, J. Konopka, J. Malínský, 2021, bioRxiv.

Saccharomyces cerevisiae Afr1 Protein Is a Protein Phosphatase 1/Glc7-Targeting Subunit That Regulates the Septin Cytoskeleton during Mating

K. Tatchell, J. Konopka, Jennifer R. Larson, 2008, Eukaryotic Cell.

The C Terminus of the Saccharomyces cerevisiaeα-Factor Receptor Contributes to the Formation of Preactivation Complexes with Its Cognate G Protein

J. Konopka, D. Jenness, M. Dosil, 2000, Molecular and Cellular Biology.

Genetic Analysis of NDT80 Family Transcription Factors in Candida albicans Using New CRISPR-Cas9 Approaches

D. Hogan, J. Konopka, Amy R. Biermann, 2018, mSphere.

DEP-Domain-Mediated Regulation of GPCR Signaling Responses

Henrik G. Dohlman, J. Thorner, H. Dohlman, 2006, Cell.

Recognition of Yeast by Murine Macrophages Requires Mannan but Not Glucan

J. Konopka, N. Dean, L. Douglas, 2010, Eukaryotic Cell.

Combining mutations in the incoming and outgoing pheromone signal pathways causes a synergistic mating defect in Saccharomyces cerevisiae

L. Giot, J. Konopka, C. Demattei, 1999, Yeast.

AFR1 promotes polarized apical morphogenesis in Saccharomyces cerevisiae

J. Konopka, C. Davis, C. Davis, 1995, Molecular and cellular biology.

Constitutive activation of the Saccharomyces cerevisiae transcriptional regulator Ste12p by mutations at the amino‐terminus

S. Fields, J. Konopka, Juan A. Crosby, 2000, Yeast.

Identification of amino acids at two dimer interface regions of the alpha-factor receptor (Ste2).

J. Konopka, Hong X. Wang, 2009, Biochemistry.

Mutational analysis of the role of N-glycosylation in alpha-factor receptor function.

J. Konopka, J B Konopka, P E Mentesana, 2001, Biochemistry.

Genetic fine-structural analysis oftheSaccharomyces cerevisiaea-pheromone receptor

J. Konopka, Genetics andMicrobiology, 1991 .

Cell lines and clinical isolates derived from Ph '-positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration ( chromosome translocation / human leukemia / tyrosine kinase / oncogene )

O. Witte, J. Konopka, S. Watanabe, 2022 .

Dominant-Negative Mutations in the G-Protein-Coupled α-Factor Receptor Map to the Extracellular Ends of the Transmembrane Segments

L. Giot, J. Konopka, C. Davis, 1998, Molecular and Cellular Biology.

Afr1p regulates the Saccharomyces cerevisiae alpha-factor receptor by a mechanism that is distinct from receptor phosphorylation and endocytosis.

J. Konopka, P. Dube, C. Davis, 1998, Genetics.

Interaction between Transmembrane Domains Five and Six of the α-Factor Receptor*

J. Konopka, P. Dube, A. DeCostanzo, 2000, The Journal of Biological Chemistry.

Genetic fine-structural analysis of the Saccharomyces cerevisiae alpha-pheromone receptor.

J. Konopka, J B Konopka, D D Jenness, 1991, Cell regulation.

Eisosomes promote the ability of Sur7 to regulate plasma membrane organization in Candida albicans

R. Rachel, J. Konopka, J. Malínský, 2016, Molecular biology of the cell.

Septin Function in Yeast Model Systems and Pathogenic Fungi

J. Konopka, Cheryl McCreary, L. Douglas, 2005, Eukaryotic Cell.

Clathrin- and Arp2/3-Independent Endocytosis in the Fungal Pathogen Candida albicans

M. Whiteway, J. Vogel, J. Konopka, 2013, mBio.

Point mutations identify a conserved region of the saccharomyces cerevisiae AFR1 gene that is essential for both the pheromone signaling and morphogenesis functions.

J. Konopka, C. Davis, C. Davis, 2000, Genetics.

Regulation of Hyphal Growth and N-Acetylglucosamine Catabolism by Two Transcription Factors in Candida albicans

J. Konopka, Kyunghun Min, Shamoon Naseem, 2017, Genetics.

Identification of residues that contribute to receptor activation through the analysis of compensatory mutations in the G protein-coupled alpha-factor receptor.

J. Konopka, Jennifer C. Lin, M. Saracino, 2005, Biochemistry.

The Candida albicans Sur7 Protein Is Needed for Proper Synthesis of the Fibrillar Component of the Cell Wall That Confers Strength

J. Latgé, V. Aimanianda, J. Konopka, 2010, Eukaryotic Cell.

The Sur7 protein regulates plasma membrane organization and prevents intracellular cell wall growth in Candida albicans.

Adam P. Rosebrock, J. Konopka, L. Douglas, 2008, Molecular biology of the cell.

A Photostable Green Fluorescent Protein Variant for Analysis of Protein Localization in Candida albicans

J. Konopka, Chengda Zhang, 2009, Eukaryotic Cell.

Scanning mutagenesis of regions in the Galpha protein Gpa1 that are predicted to interact with yeast mating pheromone receptors.

J. Konopka, D. Gladue, 2008, FEMS yeast research.

The Candida albicans ζ-crystallin homolog Zta1 promotes resistance to oxidative stress

J. Konopka, J. Nett, Rafael M. Gandra, 2023, bioRxiv.

Candida albicans resistance to hypochlorous acid

J. Konopka, L. Douglas, Kyunghun Min, 2023, mBio.

An N-acetylglucosamine transporter required for arbuscular mycorrhizal symbioses in rice and maize

U. Paszkowski, C. Gutjahr, T. Brutnell, 2017, Nature Plants.

Visualization of receptor-mediated endocytosis in yeast.

D. Botstein, J. Mulholland, M. Zerial, 1999, Molecular biology of the cell.