D. Hoel

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A general scheme for the incorporation of pharmacokinetics in low-dose risk estimation for chemical carcinogenesis: example--vinyl chloride.

D G Hoel, M. Anderson, D. Hoel, 1980, Toxicology and applied pharmacology.

A Method for the Construction of Sequential Selection Procedures

D. Hoel, 1971 .

A Survey of Adaptive Sampling for Clinical Trials

G. Weiss, M. Sobel, D. Hoel, 1975 .

Sequential analysis of binomial clinical trials

G. Weiss, R. Simon, D. Hoel, 1975 .

Comparison of sampling methods for choosing the best binomial population with delayed observations

G. Weiss, M. Sobel, D. Hoel, 1975 .

Use of historical controls for animal experiments.

D. Hoel, T. Yanagawa, 1985, Environmental health perspectives.

Trends in cancer mortality in 15 industrialized countries, 1969-1986.

E. Sondik, A. Miller, A. Swerdlow, 1992, Journal of the National Cancer Institute.

Review and evaluation of updated research on the health effects associated with low-dose ionising radiation.

D. Stram, L. Dauer, A. Brooks, 2010, Radiation protection dosimetry.

Comparisons of sequential procedures for selecting the best binomial population

M. Sobel, D. Hoel, 1972 .

The role of dose rate in radiation cancer risk: evaluating the effect of dose rate at the molecular, cellular and tissue levels using key events in critical pathways following exposure to low LET radiation

R. Preston, A. Brooks, D. Hoel, 2016, International journal of radiation biology.

A representation of mortality data by competing risks.

D G Hoel, D. Hoel, 1972, Biometrics.

Modeling the low-LET dose-response of BCR-ABL formation: predicting stem cell numbers from A-bomb data.

D. Hoel, T. Radivoyevitch, 1999, Mathematical biosciences.

Recent data obtained by pulsed-field gel electrophoresis suggest two types of double-strand breaks.

P. Hahnfeldt, R. Sachs, D. Hoel, 1998, Radiation research.

Misrejoining of double-strand breaks after X irradiation: relating moderate to very high doses by a Markov model.

R. Sachs, D. Hoel, T. Radivoyevitch, 1998, Radiation research.

Size distributions of misrejoining DNA fragments in irradiated cells.

P. Hahnfeldt, R. Sachs, D. Hoel, 1998, Mathematical biosciences.

Special Scientific Advisors

Hiroshi Sasaki, John J. Mulvihill, Marianne Berwick, 2013 .

Guidance on radiation dose limits for the lens of the eye: overview of the recommendations in NCRP Commentary No. 26

B. Klein, L. Dauer, E. Vañó, 2017, International journal of radiation biology.

Predictive Strategies for Selecting 379 NCI/NTP Chemicals Evaluated for Carcinogenic Potential: Scientific and Public Health Impact

J. Huff, D. Hoel, E. Weisburger, 1993 .

International trends in cancer mortality in France, West Germany, Italy, Japan, England and Wales, and the USA

A. Lopez, D. Davis, D. Hoel, 1990, The Lancet.

Concordance of carcinogenic response between rodent species: potency dependence and potential underestimation.

C. Portier, W. Piegorsch, D. Hoel, 1992, Risk analysis : an official publication of the Society for Risk Analysis.

Trichloroethylene risk assessment: A review and commentary

J. Fisher, D. Hoel, L. Mohr, 2009, Critical reviews in toxicology.

Properties of noise emitted by vehicular queues

George H. Weiss, David G. Hoel, G. Weiss, 1977 .

Metabolite-based internal doses used in a risk assessment of benzene.

A. J. Bailer, D. Hoel, A. John Bailer, 1989, Environmental health perspectives.

Residential mobility and risk of childhood acute lymphoblastic leukaemia: an ecological study

D. Wartenberg, D. Hoel, F. Groves, 2007, British Journal of Cancer.

Studies of the mortality of A-bomb survivors. 9. Mortality, 1950-1985: Part 3. Noncancer mortality based on the revised doses (DS86).

H. Kato, W. Schull, D. Hoel, 1992, Radiation research.

Tobacco-associated deaths

T. Sterling, D. Hoel, J. Weinkam, 1992, The Lancet.

Mechanistic and statistical insight into the large carcinogenesis bioassays on N-nitrosodiethylamine and N-nitrosodimethylamine.

J. Swenberg, P. Magee, D. Hoel, 1991, Cancer research.

Commercial tanning salons and melanoma risk

D. Hoel, 2016, Dermato-endocrinology.

Relative Toxicity of Chronic Irradiation by 45Ca β Particles and 242Cm α Particles with Respect to the Production of Lung Tumors in CBA/Ca Mice

D. Hoel, N. Priest, P. N. Brooks, 2006 .

Questions about radiation and risk estimates that remain after BEIR V.

D. Hoel, 1993, Radiation research.

Radiation risk estimation models.

D. Hoel, 1987, Environmental health perspectives.

CORRECTIONS IN THE ATOMIC BOMB DATA TO EXAMINE LOW DOSE RISK

D. Hoel, Gizelle Baker, 2003, Health physics.

Threshold models in radiation carcinogenesis.

D. Hoel, P. Li, P. Li, 1998, Health physics.

Secular trends in the distributions of the breast cancer risk factors--menarche, first birth, menopause, and weight--in Hiroshima and Nagasaki, Japan.

M. Pike, D. Hoel, T. Wakabayashi, 1983, American journal of epidemiology.

Impact of race and baseline PSA on longitudinal PSA

S. Lipsitz, D. Hoel, N. Bissada, 2006, International journal of cancer.

Ionizing Radiation and Cardiovascular Disease

D. Hoel, 2006, Annals of the New York Academy of Sciences.

Index of Contributors

D. Davis, D. Hoel, 1990 .

Association between chloroform levels in finished drinking water supplies and various site-specific cancer mortality rates.

M. D. Hogan, T. J. Mitchell, M. Hogan, 1979, Journal of environmental pathology and toxicology.

Toxicity and carcinogenic potency.

M. Pike, B. Ames, L. Bernstein, 1985, Risk analysis : an official publication of the Society for Risk Analysis.

Cosmic radiation and magnetic field exposure to airline flight crews.

G. C. Butler, B. Grosche, D. Lackland, 1998, American journal of industrial medicine.

Status of NCRP Scientific Committee 1-23 Commentary on Guidance on Radiation Dose Limits for the Lens of the Eye.

B. Klein, L. Dauer, E. Vañó, 2016, Health physics.

Modeling time-to-tumor data: analysis of the ED01 study.

K. G. Brown, D. Hoel, 1983, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Racial and anthropometric differences in plasma levels of insulin-like growth factor I and insulin-like growth factor binding protein-3.

S. Lipsitz, D. Hoel, N. Bissada, 2005, Urology.

Estimated Cancer Risk Associated with Occupational Asbestos Exposure

M. D. Hogan, M. Hogan, D. Hoel, 1981 .

Early mortality rate of atomic bomb survivors based on House Reconstruction Survey.

Y. Okumura, H. Kondo, M. Mine, 1994, International journal of radiation biology.

Some applications of renewal theory on the whole line

D. Hoel, K. Crump, 1970, Journal of Applied Probability.

SAMPLE SIZE REQUIREMENTS: TESTS OF EQUALITY OF SEVERAL GAUSSIAN MEANS.

K. Bowman, D. Hoel, Kastenbaum, 1969 .

Cardiovascular effects of fission neutron or 60Co γ exposure in the B6CF1 mouse

B. Carnes, D. Hoel, 2017, International journal of radiation biology.

Mortality of Atomic Bomb Survivors Predicted from Laboratory Animals

B. Carnes, D. Hoel, D. Grahn, 2003, Radiation research.

‘Hormonal’ risk factors, ‘breast tissue age’ and the age-incidence of breast cancer

D. G. Hoel, M. C. Pike, J. T. Casagrande, 1983, Nature.

Age-specific models of mortality and tumor onset for historical control animals in the National Toxicology Program's carcinogenicity experiments.

D G Hoel, C J Portier, C. Portier, 1986, Cancer research.

Incorporating Historical Controls in Testing for a Trend in Proportions

Takashi Yanagawa, David G. Hoel, D. Hoel, 1986 .

Fundamental carcinogenic processes and their implications for low dose risk assessment.

D G Hoel, K S Crump, C. Langley, 1976, Cancer research.

Statistical analysis of survival experiments.

D G Hoel, D. Hoel, H E Walburg, 1972, Journal of the National Cancer Institute.

Optimal design of the chronic animal bioassay.

C. Portier, D. Hoel, Christopher J. Portier, 1983, Journal of toxicology and environmental health.

Biologically-based risk estimation for radiation-induced chronic myeloid leukemia

D. Hoel, T. Radivoyevitch, 2000, Radiation and environmental biophysics.

Agricultural exposures and cancer trends in developed countries.

A. Blair, D. Davis, D. Hoel, 1993, Environmental health perspectives.

Some Tautologous Aspects of the Comparison of Carcinogenic Potency in Rats and Mice

David G. Hoel, Malcolm C. Pike, Bruce N. Ames, 1985 .

Preparation of lung microsomes and a comparison of the distribution of enzymes between subcellular fractions of rabbit lung and liver.

G. Hook, D. Hoel, J. Bend, 1972, The Journal of pharmacology and experimental therapeutics.

APPENDIX A SIMPLE TWO-COMPARTMENTAL MODEL APPLICABLE TO ENZYME REGULATION

D. Hoel, 1970 .

Regulation of tyrosine alpha-ketoglutarate transaminase in rat liver. IX. Studies of the mechanisms of hormonal inductions in cultured hepatoma cells.

F. Kenney, K. L. Lee, D. Hoel, 1970, The Journal of biological chemistry.

Application of Cryopreserved Human Hepatocytes in Trichloroethylene Risk Assessment: Relative Disposition of Chloral Hydrate to Trichloroacetate and Trichloroethanol

J. McMillan, D. Hoel, L. Mohr, 2006, Environmental health perspectives.

Medical hypothesis: xenoestrogens as preventable causes of breast cancer.

D G Hoel, D L Davis, T Woodruff, 1993, Environmental health perspectives.

Tables of gehan's generalized Wilcoxon test with fixed point censoring

J. Haseman, D. Hoel, 1974 .

Nonlinearity of dose-response functions for carcinogenicity.

D G Hoel, C J Portier, C. Portier, 1994, Environmental health perspectives.

A review and critique of U.S. EPA's risk assessments for asbestos

E. Anderson, E. Lau, S. Moolgavkar, 2014, Critical reviews in toxicology.

New Models for Evaluation of Radiation-Induced Lifetime Cancer Risk and its Uncertainty Employed in the UNSCEAR 2006 Report

D. G. Hoel, R. Wakeford, C. R. Muirhead, 2008, Radiation research.

Statistical modeling of animal bioassay data with variable dosing regimens: example--vinyl chloride.

K. G. Brown, D. Hoel, 1986, Risk analysis : an official publication of the Society for Risk Analysis.

Animal experimentation and its relevance to man.

D. Hoel, 1979, Environmental health perspectives.

Biologically based models for risk assessment.

C. Portier, D. Hoel, N. Kaplan, 1990, IARC scientific publications.

Implication of nonlinear kinetics on risk estimation in carcinogenesis.

D G Hoel, M. Anderson, D. Hoel, 1983, Science.

Life-span exposure to sinusoidal-50 Hz magnetic field and acute low-dose γ radiation induce carcinogenic effects in Sprague-Dawley rats

D. Hoel, L. Giuliani, M. Soffritti, 2016, International journal of radiation biology.

The impact of toxicity on carcinogenicity studies: implications for risk assessment.

M. D. Hogan, J. Huff, J. Haseman, 1988, Carcinogenesis.

LUNG, LIVER AND BONE CANCER MORTALITY AFTER PLUTONIUM EXPOSURE IN BEAGLE DOGS AND NUCLEAR WORKERS

Dulaney A. Wilson, D. Lackland, D. Hoel, 2010, Health physics.

Lung Fibrosis and Lung Cancer Incidence in Beagle Dogs that Inhaled 238PuO2 or 239PuO2

Dulaney A. Wilson, D. Hoel, J. Diel, 2009, Health physics.

Comments on the DDREF Estimate of the BEIR VII Committee

D. Hoel, 2015, Health physics.

Dose-Response in Radiation Carcinogenesis: Animal Studies

D. Preston, D. Hoel, 1985 .

Insufficient Sun Exposure Has Become a Real Public Health Problem

D. Llewellyn, D. Butterfield, R. Chowdhury, 2020, International journal of environmental research and public health.

Influence of death certificate errors on cancer mortality trends.

E. Ron, K. Mabuchi, R. Carter, 1993, Journal of the National Cancer Institute.

Stable chromosome aberrations and ionizing radiation in airline pilots.

G. C. Butler, D. Hoel, E. Bryant, 2003, Aviation, space, and environmental medicine.

Meta-analysis of standardized incidence and mortality rates of childhood leukaemia in proximity to nuclear facilities.

P. J. Baker, D G Hoel, D. Hoel, 2007, European journal of cancer care.

Relative toxicity of 45Ca β-particles and 242Cm α-particles following their intravenous injection into mice as radiolabelled FAP

D. Hoel, N. Priest, P. N. Brooks, 2010, International journal of radiation biology.

137Cesium Exposure and Spirometry Measures in Ukrainian Children Affected by the Chernobyl Nuclear Incident

E. Svendsen, Timothy A Mousseau, D. Hoel, 2010, Environmental health perspectives.

Life table analysis with small numbers of cases: an example—multiple myeloma in hiroshima and nagasaki

R. Jennrich, D. Hoel, 1985 .

Studies of the mortality of A-bomb survivors. Report 7. Mortality, 1950-1978: Part II. Mortality from causes other than cancer and mortality in early entrants.

H. Kato, W. Schull, D. Hoel, 1982, Radiation research.

Unexplained increases in cancer incidence in the United States from 1975 to 1994: possible sentinel health indicators?

A. Sasco, G. Dinse, D. Umbach, 1999, Annual review of public health.

Administration of lower doses of radium-224 to ankylosing spondylitis patients results in no evidence of significant overall detriment

L. Dauer, D. Hoel, N. Priest, 2020, PloS one.

Nuclear epidemiologic studies and the estimation of DREF

D. Hoel, 2018, International journal of radiation biology.

Is occupational organic solvent exposure a risk factor for scleroderma?

M. Dosemeci, R. Knapp, R. Silver, 1998, Arthritis and rheumatism.

Estimation of risks of irreversible, delayed toxicity.

D G Hoel, U Saffiotti, D W Gaylor, 1975, Journal of toxicology and environmental health.

Childhood exposures to Rn-222 and background gamma radiation in the uranium provinces of south Kazakhstan and northern Kyrgyzstan.

D. Hoel, N. Priest, M. Burkitbayev, 2013, Journal of environmental radioactivity.

Ionizing radiation and cancer prevention.

D. Hoel, 1995, Environmental health perspectives.

The risks and benefits of sun exposure 2016

M. Holick, F. D. de Gruijl, M. Berwick, 2016, Dermato-endocrinology.

Mathematical models for estimating mutation rates in cell populations

David G. Hoel, Kenny S. Crump, D. Hoel, 1974 .

Impact of nutrients on insulin-like growth factor-I, insulin-like growth factor binding protein-3 and their ratio in African American and white males

S. Lipsitz, D. Hoel, B. Hoel, 2007, Public Health Nutrition.

Exploring relationships between mutagenic and carcinogenic potencies.

W W Piegorsch, D G Hoel, W. Piegorsch, 1988, Mutation research.

Using mortality data to estimate radiation effects on breast cancer incidence.

G. Dinse, D. Hoel, 1990, Environmental health perspectives.

Risk Quantitation and Regulatory Policy

Richard A. Merrill, D. G. Hoel, F. Perera, 1985 .

Applications of the Poly-K Statistical Test to Life-Time Cancer Bioassay Studies

M. Gebregziabher, D. Hoel, 2009, Human and ecological risk assessment : HERA.

A Balanced Approach To Risk Assessment

D. Hoel, 1991, Toxicology and industrial health.

Altitude, radiation, and mortality from cancer and heart disease.

K. G. Brown, C. Weinberg, D. Hoel, 1987, Radiation research.

Evidence of Health Impacts of Sulfate-and Nitrate-Containing Particles in Ambient Air

Richard Reiss, George Hidy, E. Anderson, 2007, Inhalation toxicology.

Statistical methods in cancer epidemiology : proceedings of a conference held at the Radiation Effects Research Foundation, Hiroshima, Japan, 1-2 March 1984

W. Blot, D. Hoel, 平山雄, 1985 .

Ligand/receptor binding for 2,3,7,8-TCDD: implications for risk assessment.

L Edler, G. Clark, M. Kohn, 1993, Fundamental and applied toxicology : official journal of the Society of Toxicology.

BEIR V Estimates of Excess Cancer Mortality

D. Hoel, R. Cooper, W. Ellett, 1991 .

Decreasing cardiovascular disease and increasing cancer among whites in the United States from 1973 through 1987. Good news and bad news.

G. Dinse, D. Davis, D. Hoel, 1994, JAMA.

DETERMINING THE RELATIVE TOXICITY AND RBE OF INTERNAL EMITTERS IN ANIMALS

D. Hoel, N. D. Priest, 2010, Health Physics.

Clinical breast examination practices among women undergoing screening mammography.

D. Hoel, L. Baron, K. McGreevy, 2002, Radiology.

Diesel Emissions and Lung Cancer : Epidemiology and Quantitative Risk Assessment

Daniel Krewski, Kyle Steenland, Dale Hattis, 1999 .

A theoretical study of the effect of methylation or ethylation at O6-guanine in the structure and energy of DNA double strands.

T. Darden, L. Pedersen, D. Deerfield, 1988, Carcinogenesis.

Uses of benchmark dose methodology in quantitative risk assessment.

T. Starr, D. Hoel, J. Goodman, 2005, Regulatory toxicology and pharmacology : RTP.

Omeprazole, cytochrome P450, and chemical carcinogenesis.

G. Lucier, D. Hoel, C. Thompson, 1992, Gastroenterology.

Comparing cancer risks between radiation and dioxin exposure based on two‐stage model

David G. Hoel, D. Hoel, Tsuyoshi Nakamura, 2003 .

Is brain cancer mortality increasing in industrial countries?

A. Ahlbom, C. Percy, D. Davis, 1991, American journal of industrial medicine.

An Extension of Paulson's Selection Procedure

M. Mazumdar, D. Hoel, 1968 .

Using median regression to obtain adjusted estimates of central tendency for skewed laboratory and epidemiologic data.

E. Rimm, S. Lipsitz, J. Linder, 2009, Clinical chemistry.

Sample size requirements: one-way analysis of variance

K. Bowman, M. Kastenbaum, D. Hoel, 1970 .

Mortality among US commercial pilots and navigators.

B. Grosche, D. Lackland, M. Dosemeci, 1998, Journal of occupational and environmental medicine.

Serial dilutions: Error effects and optimal designs

D. Hoel, G. Chase, 1975 .

Design of animal carcinogenicity studies for goodness-of-fit of multistage models.

D G Hoel, C J Portier, C. Portier, 1984, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Figuring out Cancer

D. Hoel, D. Davis, 1992, International journal of health services : planning, administration, evaluation.

Issues concerning the estimation of the TD50.

D G Hoel, C J Portier, C. Portier, 1987, Risk analysis : an official publication of the Society for Risk Analysis.

Some tautologous aspects of the comparison of carcinogenic potency in rats and mice.

M. Pike, B. Ames, L. Bernstein, 1985, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Sun Exposure Public Health Directives

F. D. de Gruijl, D. Hoel, 2018, International journal of environmental research and public health.

Residential radon exposure and lung cancer risk: commentary on Cohen's county-based study.

C. B. Meinhold, D G Hoel, C. Heath, 2004, Health physics.

Closed sequential tests of an exponential parameter

D. Hoel, 1968 .

A two-stage procedure for choosing the better of two binomial populations

George H. Weiss, David G. Hoel, Milton Sobel, 1972 .

An Inverse Stopping Rule for Play-the-Winner Sampling

D. Hoel, 1972 .

Statistical Aspects of Chemical Mixtures

David G. Hoel, D. Hoel, 1987 .

An empirical comparison of methods used to estimate carcinogenic potency in long-term animal bioassays: lifetable vs summary incidence data.

J. Kaldor, L. Bernstein, L. Gold, 1986, Fundamental and applied toxicology : official journal of the Society of Toxicology.

The use of covariate information in the sequential analysis of dichotomous response experiments

G. Weiss, R. Simon, D. Hoel, 1977 .

Synergism between sinusoidal-50 Hz magnetic field and formaldehyde in triggering carcinogenic effects in male Sprague-Dawley rats.

D. Hoel, L. Giuliani, M. Soffritti, 2016, American journal of industrial medicine.

Health among commercial airline pilots.

D T Lackland, D G Hoel, G. C. Butler, 2001, Aviation, space, and environmental medicine.

Flight deck magnetic fields in commercial aircraft.

G. C. Butler, D. Lackland, D. Hoel, 2000, American journal of industrial medicine.

Second Primary Cancers and Cardiovascular Disease after Radiation Therapy

D. Hoel, 2012 .

Comprehensive Evaluation of Human Data

P. Landrigan, D. Hoel, 1987 .

Comparison of Certain Small-Sample Poisson Probability Estimates

D. Gaver, D. Hoel, 1970 .

Predictive strategies for selecting 379 NCI/NTP chemicals evaluated for carcinogenic potential: scientific and public health impact.

D G Hoel, E K Weisburger, J. Huff, 1993, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Perspective and overview of the concepts and value of hazard identification as the initial phase of risk assessment for cancer and human health.

J. Huff, D. Hoel, 1992, Scandinavian journal of work, environment & health.

Racial, age, and rural/urban disparity in cervical cancer incidence.

S. Lipsitz, D. Lackland, D. Hoel, 2000, Annals of epidemiology.

Statistical design of toxicity assays: role of genetic structure of test animal population.

J. Haseman, D. Hoel, 1979, Journal of toxicology and environmental health.

Incorporation of background in dose-response models.

D. Hoel, 1980, Federation proceedings.

Low-dose-rate extrapolation using the multistage model.

C. Portier, D. Hoel, C Portier, 1983, Biometrics.

Comparisons of models for estimation of safe doses using measures of the heaviness of tail of a distribution

T. Yanagimoto, D. Hoel, 1980 .

STATISTICAL EXTRAPOLATION METHODS FOR ESTIMATING RISKS FROM ANIMAL DATA

D G Hoel, D. Hoel, 1976, Annals of the New York Academy of Sciences.

Statistical measures of risk.

D. Hoel, 1982, Drug metabolism reviews.

Some investigations and simulation studies of canonical analysis

J. Beauchamp, D. Hoel, 1973 .

Review and evaluation of updated research on the health effects associated with low-dose ionising radiation.

D. Stram, L. Dauer, A. Brooks, 2010, Radiation protection dosimetry.

Sample size requirements: randomized block designs

K. Bowman, M. Kastenbaum, D. Hoel, 1970 .

Type 1 error of trend tests in proportions and the design of cancer screens

David G. Hoel, Christopher J. Portier, C. Portier, 1984 .

Sequential Testing of Sample Size

D. Hoel, 1968 .

Quantitative Risk Assessment in the 1970s: A Personal Remembrance

D. Hoel, 2018, Dose-response : a publication of International Hormesis Society.

Properties of the Neyman-Scott carcinogenesis model at low dose rates

D. Hoel, C. Schoenfelder, 1979 .