J. Hall

发表

Catabolism of Tryptophan by Trypanosoma evansi

A. Sawalhy, J. Seed, H. Attar, 1995, The Journal of eukaryotic microbiology.

Inhibition by Dications of In Vitro Growth of Leishmania major and Leishmania tropica: Causative Agents of Old World Cutaneous Leishmaniasis

Arvind Kumar, D. Boykin, J. Hall, 2008, The Journal of parasitology.

In vitro activity of dicationic compounds against a North American foxhound isolate of Leishmania infantum.

Arvind Kumar, D. Boykin, J. Hall, 2007, Veterinary parasitology.

Development of Pentamidine Analogues as New Agents for the Treatment of Pneumocystis carinii Pneumonia a

B. Berger, J. Hall, R. Tidwell, 1990, Annals of the New York Academy of Sciences.

Anti-Pneumocystis Activities of Aromatic Diamidoxime Prodrugs

J. Kerrigan, J. Stanko, J. Hall, 1998, Antimicrobial agents and chemotherapy.

CYP1A1 and CYP1B1-mediated biotransformation of the antitrypanosomal methamidoxime prodrug DB844 forms novel metabolites through intramolecular rearrangement.

D. Boykin, J. Hall, R. Tidwell, 2014, Journal of pharmaceutical sciences.

UNUSUAL DEHYDROXYLATION OF ANTIMICROBIAL AMIDOXIME PRODRUGS BY CYTOCHROME b5 AND NADH CYTOCHROME b5 REDUCTASE

L. Trepanier, D. Boykin, J. R. Kurian, 2005, Drug Metabolism and Disposition.

Distribution and quantitation of the anti-trypanosomal diamidine 2,5-bis(4-amidinophenyl)furan (DB75) and its N-methoxy prodrug DB289 in murine brain tissue.

C. R. Bagnell, J. Hall, R. Tidwell, 2004, Acta tropica.

Transport of Dicationic Drugs Pentamidine and Furamidine by Human Organic Cation Transporters

X. Ming, J. Hall, D. Thakker, 2009, Drug Metabolism and Disposition.

Accumulation and Intracellular Distribution of Antitrypanosomal Diamidine Compounds DB75 and DB820 in African Trypanosomes

D. Boykin, J. Hall, R. Tidwell, 2006, Antimicrobial Agents and Chemotherapy.

Anti-pneumocystis activity of bis-amidoximes and bis-o-alkylamidoximes prodrugs

Arvind Kumar, D. Boykin, J. Hall, 1996 .

Structures and Rotational Barriers of a Diiodobinorsnoutane: Energetic Preference for Gauche Conformation.

J. Hall, J. McCauley, M. Forman, 2016, The Journal of organic chemistry.

Development and SAR of functionally selective allosteric modulators of GABAA receptors.

E. Christian, C. Alhambra, J. Arriza, 2011, Bioorganic & medicinal chemistry.

New Treatment Option for Second-Stage African Sleeping Sickness: In Vitro and In Vivo Efficacy of Aza Analogs of DB289

D. Boykin, J. Hall, R. Brun, 2009, Antimicrobial Agents and Chemotherapy.

Synthesis of three alpha 7 agonists in labeled form.

J. Hall, C. Elmore, S. Landvatter, 2014, Journal of labelled compounds & radiopharmaceuticals.

Carbamate prodrugs of N-alkylfuramidines.

D. Boykin, J. Hall, R. Tidwell, 2008, European journal of medicinal chemistry.

Anti-Pneumocystis carinii pneumonia activity of dicationic carbazoles

W. Wilson, D. Boykin, J. Hall, 1997 .

Synthesis and in vitro antiprotozoal activities of dicationic 3,5-diphenylisoxazoles.

J. Hall, R. Brun, R. Tidwell, 2007, Journal of medicinal chemistry.

Antiparasitic compounds that target DNA.

W. Wilson, D. Boykin, J. Hall, 2008, Biochimie.

Synthesis and in vitro antiprotozoal activity of bisbenzofuran cations.

J. Hall, R. Brun, K. Werbovetz, 2007, Journal of medicinal chemistry.

Dicationic dibenzofuran derivatives as anti-Pneumocystis carinii pneumonia agents: synthesis, DNA binding affinity, and anti-P. carinii activity in an immunosuppressed rat model

W. Wilson, J. Hall, R. Tidwell, 1999 .

Anti-Pneumocystis carinii Pneumonia Activity of Dicationic Carbazoles.

W. Wilson, D. Boykin, J. Hall, 1998 .

Synthesis, DNA affinity, and antiprotozoal activity of linear dications: Terphenyl diamidines and analogues.

W. Wilson, D. Boykin, J. Hall, 2006, Journal of medicinal chemistry.

Dications that target the DNA minor groove: compound design and preparation, DNA interactions, cellular distribution and biological activity.

W. Wilson, Binh Nguyen, D. Boykin, 2005, Current medicinal chemistry. Anti-cancer agents.

Chapter 3 – Trypanosomes Causing Disease in Man in Africa

J. Seed, J. Hall, 1992 .

Pharmacology of DB844, an Orally Active aza Analogue of Pafuramidine, in a Monkey Model of Second Stage Human African Trypanosomiasis

D. Boykin, J. Hall, R. Brun, 2012, PLoS neglected tropical diseases.

Diphenyl Furans and Aza Analogs: Effects of Structural Modification on In Vitro Activity, DNA Binding, and Accumulation and Distribution in Trypanosomes

W. Wilson, Arvind Kumar, D. Boykin, 2007, Antimicrobial Agents and Chemotherapy.

CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]

D. Boykin, D. Zeldin, J. Hall, 2006, Drug Metabolism and Disposition.

Synthesis of novel quinolone and quinoline-2-carboxylic acid (4-morpholin-4-yl-phenyl)amides: a late-stage diversification approach to potent 5HT1B antagonists.

J. Hall, J. McCauley, T. Hudzik, 2007, Bioorganic & medicinal chemistry.

Synthesis of the NK3 receptor antagonist AZD2624 in C‐14‐, H‐3‐ and C‐13‐labeled forms

J. Hall, C. Elmore, P. Dorff, 2011 .

Novel Arylimidamides for Treatment of Visceral Leishmaniasis

R. Madhubala, D. Kyle, W. Wilson, 2010, Antimicrobial Agents and Chemotherapy.

Efﬁcacy of the Novel Diamidine Compound 2,5-Bis(4-Amidinophenyl)-Furan-Bis- O -Methlylamidoxime (Pafuramidine, DB289) against Trypanosoma brucei rhodesiense Infection in Vervet Monkeys after Oral Administration (cid:1)

J. Hall, J. Ndung'u, R. Brun, 2009 .

In vitro tryptophan catabolism by Trypanosoma (trypanozoon) brucei gambiense, T.(T.) equiperdum, T. (herpetosoma) lewisi and T.(h.) musculi

J. Seed, J. Hall, K. Dahm, 1981 .

Quantification of tryptophan catabolites from Trypanosoma brucei gambiense in vitro

J. Seed, J. Hall, K. Dahm, 1981 .

Quantitation of aromatic amino acid catabolites in urine of mice acutely infected with Trypanosoma brucei gambiense

J. Seed, J. Hall, 1981 .

A Semiphysiologically Based Pharmacokinetic Modeling Approach to Predict the Dose-Exposure Relationship of an Antiparasitic Prodrug/Active Metabolite Pair

Harvey J. Clewell, Miyoung Yoon, Kim L. R. Brouwer, 2012, Drug Metabolism and Disposition.

Mechanisms Underlying Differences in Systemic Exposure of Structurally Similar Active Metabolites: Comparison of Two Preclinical Hepatic Models

K. Brouwer, J. Hall, M. Paine, 2011, Journal of Pharmacology and Experimental Therapeutics.

Human Enteric Microsomal CYP4F Enzymes O-Demethylate the Antiparasitic Prodrug Pafuramidine

S. Kornbluth, D. Zeldin, J. Hall, 2007, Drug Metabolism and Disposition.

Metabolites of an orally active antimicrobial prodrug, 2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime, identified by liquid chromatography/tandem mass spectrometry.

D. Boykin, Lianwen Zhou, J. Hall, 2002, Journal of mass spectrometry : JMS.

A gel‐free MS‐based quantitative proteomic approach accurately measures cytochrome P450 protein concentrations in human liver microsomes

Jennifer B Dennison, S. Kornbluth, J. Hall, 2008, Proteomics.

Anti-Pneumocystis carinii pneumonia activity of dicationic diaryl methylprimidines

W. Wilson, Arvind Kumar, D. Boykin, 1998 .

Safety, Pharmacokinetic, and Efficacy Studies of Oral DB868 in a First Stage Vervet Monkey Model of Human African Trypanosomiasis

D. Boykin, Qiang Liu, J. Hall, 2013, PLoS neglected tropical diseases.

O-alkoxyamidine prodrugs of furamidine: in vitro transport and microsomal metabolism as indicators of in vivo efficacy in a mouse model of Trypanosoma brucei rhodesiense infection.

D. Boykin, J. Hall, R. Brun, 2004, Journal of medicinal chemistry.

Enhanced Permeability of the Antimicrobial Agent 2,5-Bis(4-Amidinophenyl)Furan Across Caco-2 Cell Monolayers Via Its Methylamidoxime Prodrug

D. Boykin, Lianwen Zhou, J. Hall, 2002, Pharmaceutical Research.

Synthesis of a delta opioid agonist in [2H6], [2H4], [11C], and [14C] labeled forms

C. Halldin, J. Hall, C. Elmore, 2011 .

Extended Aromatic Furan Amidino Derivatives as Anti‐Pneumocystis carinii Agents.

W. Wilson, Arvind Kumar, D. Boykin, 1999 .

Late-occurring and Long-circulating Metabolites of GABAAα2,3 Receptor Modulator AZD7325 Involving Metabolic Cyclization and Aromatization: Relevance to MIST Analysis and Application for Patient Compliance

Mark A. Smith, R. Lewis, J. Hall, 2018, Drug Metabolism and Disposition.

Nucleoside analogues achieve high concentrations in seminal plasma: relationship between drug concentration and virus burden.

J. Hall, J. Eron, S. Fiscus, 1999, The Journal of infectious diseases.

Structure-activity relationships of analogs of pentamidine against Plasmodium falciparum and Leishmania mexicana amazonensis

D. Kyle, M. Grogl, J. Hall, 1990, Antimicrobial Agents and Chemotherapy.

Transport of Dicationic Drugs Pentamidine and Furamidine by Human Organic Cation Transporters

J. Hall, D. Thakker, R. Tidwell, 2009, Drug Metabolism and Disposition.

Analogues of 1,5-bis(4-amidinophenoxy)pentane (pentamidine) in the treatment of experimental Pneumocystis carinii pneumonia.

J. Hall, J. Hall, R. Tidwell, 1990, Journal of medicinal chemistry.

Simultaneous determination of lamivudine and zidovudine concentrations in human seminal plasma using high-performance liquid chromatography and tandem mass spectrometry.

J. Eron, J. Hall, J. Eron, 2000, Journal of chromatography. B, Biomedical sciences and applications.

1,5-Bis(4-amidinophenoxy)pentane (pentamidine) is a potent inhibitor of [3H]idazoxan binding to imidazoline I2 binding sites.

D. H. Wood, J. Hall, J. Hall, 1998, European journal of pharmacology.

Problems and Pitfalls in the Assay of Pentamidine

B. Berger, J. Hall, J. Hall, 1992, Clinical pharmacokinetics.

2,4-Diphenyl furan diamidines as novel anti-Pneumocystis carinii pneumonia agents.

W. Wilson, D. Boykin, J. Hall, 1999, Journal of medicinal chemistry.

Extended aromatic furan amidino derivatives as anti-Pneumocystis carinii agents.

W. Wilson, Arvind Kumar, D. Boykin, 1998, Journal of medicinal chemistry.

Primary and secondary metabolism of pentamidine by rats

B. Berger, J. Hall, J. Hall, 1992, Antimicrobial Agents and Chemotherapy.