Yan Xu

Pei Tang, Yan Xu, P. Tang, 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

White Matter Injury in Global Cerebral Ischemia

Yan Xu, Shinichi Nakao, 2014 .

Deferoxamine Improves Early Postresuscitation Reperfusion after Prolonged Cardiac Arrest in Rats

Yan Xu, P. Tang, S. Liachenko, 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Dominant Alcohol-Protein Interaction via Hydration-Enabled Enthalpy-Driven Binding Mechanism.

A. Kleinhammes, Yue Wu, Yan Xu, 2015, The journal of physical chemistry. B.

Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC.

A. Cohen, T. Tillman, Yan Xu, 2017, Structure.

Regulation and drug modulation of a voltage-gated sodium channel: Pivotal role of the S4–S5 linker in activation and slow inactivation

M. Klein, R. Eckenhoff, V. Carnevale, 2021, Proceedings of the National Academy of Sciences.

Fluorine-19 NMR and computational quantification of isoflurane binding to the voltage-gated sodium channel NaChBac

M. Klein, R. Eckenhoff, V. Carnevale, 2016, Proceedings of the National Academy of Sciences.

Stem Cells Decreased Neuronal Cell Death after Hypoxic Stress in Primary Fetal Rat Neurons in Vitro 1

Yan Xu, T. Sakai, 2012, Cell transplantation.

A Thermal Place Preference Test for Discovery of Neuropathic Pain Drugs.

T. Tillman, Yan Xu, P. Tang, 2020, ACS chemical neuroscience.

Anionic lipid and cholesterol interactions with alpha4beta2 nAChR: insights from MD simulations.

M. H. Cheng, Yan Xu, P. Tang, 2009, The journal of physical chemistry. B.

Predictors of Radiographic Knee Osteoarthritis After Anterior Cruciate Ligament Reconstruction

Freddie H. Fu, Ryan T. Li, J. Irrgang, 2011, The American journal of sports medicine.

Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine

A. Cohen, X. Kong, Jianjun Pan, 2012, Nature Communications.

Potential Therapeutic Targets for Cerebral Resuscitation After Global Ischemia

Yan Xu, 2012 .

Mechanistic insights into xenon inhibition of NMDA receptors from MD simulations.

Yan Xu, P. Tang, Lu Liu, 2010, The journal of physical chemistry. B.

Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites

M. Klein, R. Eckenhoff, V. Carnevale, 2018, The Journal of general physiology.

Immune Modulation by Volatile Anesthetics

B. Lu, Yan Xu, P. Tang, 2016, Anesthesiology.

Concentration‐dependent isoflurane effects on depolarization‐evoked glutamate and GABA outflows from mouse brain slices

Yan Xu, P. Tang, G. Somogyi, 1999, British journal of pharmacology.

Ketamine Inhibition of the Pentameric Ligand-Gated Ion Channel GLIC.

Yan Xu, P. Tang, Qiang Chen, 2017, Biophysical journal.

NMR resolved multiple anesthetic binding sites in the TM domains of the α4β2 nAChR.

V. Bondarenko, D. Mowrey, Yan Xu, 2013, Biochimica et biophysica acta.

NMR structures of the transmembrane domains of the α4β2 nAChR.

V. Bondarenko, D. Mowrey, T. Tillman, 2012, Biochimica et biophysica acta.

Direct Pore Binding as a Mechanism for Isoflurane Inhibition of the Pentameric Ligand-gated Ion Channel ELIC

A. Cohen, Yan Xu, P. Tang, 2015, Scientific Reports.

Large-scale molecular dynamics simulations of general anesthetic effects on the ion channel in the fully hydrated membrane: The implication of molecular mechanisms of general anesthesia

Pei Tang, Yan Xu, P. Tang, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Use of a problem-based learning discussion format to teach anesthesiology residents research fundamentals.

Yan Xu, T. Sakai, S. Valenti, 2013, Journal of clinical anesthesia.

NMR Studies of Drug Interaction with Membranes and Membrane-Associated Proteins

Yan Xu, P. Tang, V. Yushmanov, 2002, Bioscience reports.

Edaravone, a free radical scavenger, mitigates both gray and white matter damages after global cerebral ischemia in rats

K. Shingu, Yan Xu, H. Tomimoto, 2009, Brain Research.

Potential Treatment of Cerebral Global Ischemia with Oct‐4+ Umbilical Cord Matrix Cells

Claudia J. Bode, C. Bode, Marc Uy, 2007, Stem cells.

Four-alpha-helix bundle with designed anesthetic binding pockets. Part I: structural and dynamical analyses.

J. Johansson, V. Bondarenko, Yan Xu, 2008, Biophysical journal.

Four-alpha-helix bundle with designed anesthetic binding pockets. Part II: halothane effects on structure and dynamics.

J. Johansson, V. Bondarenko, Yan Xu, 2008, Biophysical journal.

NMR study of general anesthetic interaction with nAChR beta2 subunit.

V. Bondarenko, Yan Xu, P. Tang, 2008, Biophysical journal.

Four-α-Helix Bundle with Designed Anesthetic Binding Pockets I : Structural and Dynamical Analyses

J. Johansson, V. Bondarenko, Yan Xu, 2008 .

Structure of the first transmembrane domain of the neuronal acetylcholine receptor beta2 subunit.

V. Bondarenko, Yan Xu, P. Tang, 2008, Biophysical journal.

Structure and dynamics of the second and third transmembrane domains of human glycine receptor.

Yan Xu, P. Tang, Ling Li, 2005, Biochemistry.

Functional Tolerance to Cysteine Mutations in Human α7 Nicotinic Acetylcholine Receptors.

T. Tillman, Yan Xu, P. Tang, 2020, ACS chemical neuroscience.

Structures of highly flexible intracellular domain of human α7 nicotinic acetylcholine receptor

J. Coleman, V. Bondarenko, T. Tillman, 2022, Nature communications.

Functional Human α 7 nAChR from E . coli 1 Functional Human α 7 Nicotinic Acetylcholine Receptor ( nAChR ) Generated from E . coli

Peijun Zhang, K. Xiao, T. Tillman, 2016 .

Dynamics of firefly luciferase inhibition by general anesthetics: Gaussian and anisotropic network analyses.

Pei Tang, Agnieszka Szarecka, Yan Xu, 2007, Biophysical journal.

Delays in Cardiopulmonary Resuscitation, Defibrillation, and Epinephrine Administration All Decrease Survival in In-hospital Cardiac Arrest

J. Ornato, R. Berg, V. Nadkarni, 2019, Anesthesiology.

Functional Human α7 Nicotinic Acetylcholine Receptor (nAChR) Generated from Escherichia coli*

Peijun Zhang, K. Xiao, T. Tillman, 2016, The Journal of Biological Chemistry.

Homology modeling and molecular dynamics simulations of transmembrane domain structure of human neuronal nicotinic acetylcholine receptor.

Pei Tang, Yan Xu, P. Tang, 2005, Biophysical journal.

Critical role of water in the binding of volatile anesthetics to proteins.

A. Kleinhammes, Yue Wu, Yan Xu, 2013, The journal of physical chemistry. B.

Insights Into Distinct Modulation Of Î±7 And Î±7Î22 Nicotinic Acetylcholine Receptors By The Volatile Anesthetic

Qiang Liu, V. Bondarenko, D. Mowrey, 2021 .

Insights into Distinct Modulation of α7 and α7β2 Nicotinic Acetylcholine Receptors by the Volatile Anesthetic Isoflurane*

Pei Tang, Qiang Chen, Jie Wu, 2013, The Journal of Biological Chemistry.

Open-channel structures of the human glycine receptor α1 full-length transmembrane domain.

Peijun Zhang, A. Makhov, D. Mowrey, 2013, Structure.

ADC characterization of region‐specific response to cerebral perfusion deficit in rats by MRI at 9.4 T

Yan Xu, P. Tang, S. Liachenko, 2002, Magnetic resonance in medicine.

Parametrization of 2-Bromo-2-Chloro-1,1,1-Trifluoroethane (Halothane) and Hexafluoroethane for Nonbonded Interactions

Pei Tang, Troy Wymore, Yan Xu, 2004 .

Atomistic insights into human Cys-loop receptors by solution NMR.

D. Mowrey, Yan Xu, P. Tang, 2015, Biochimica et biophysica acta.

Structural basis of neurosteroid anesthetic action on GABAA receptors

A. Cohen, T. Tillman, Yan Xu, 2018, Nature Communications.

General Anesthetic Binding to α4β2 nAChR and Its Effects on Global Dynamics

Yan Xu, P. Tang, D. Willenbring, 2009 .

Steered molecular dynamics simulations of Na+ permeation across the gramicidin A channel.

Yan Xu, P. Tang, Zhanwu Liu, 2006, The journal of physical chemistry. B.

The role of structured water in mediating general anesthetic action on alpha4beta2 nAChR.

Yan Xu, P. Tang, D. Willenbring, 2010, Physical chemistry chemical physics : PCCP.

Percolation Model of Sensory Transmission and Loss of Consciousness Under General Anesthesia.

Pei Tang, Yan Xu, David D Mowrey, 2015, Physical review letters.

Anesthetic binding in a pentameric ligand-gated ion channel: GLIC.

M. H. Cheng, Yan Xu, P. Tang, 2010, Biophysical journal.

Faster Recovery of Cerebral Perfusion in SOD1-Overexpressed Rats After Cardiac Arrest and Resuscitation

P. Chan, Yan Xu, P. Tang, 2009, Stroke.

Structures of highly flexible intracellular domain of human α7 nicotinic acetylcholine receptor

J. Coleman, V. Bondarenko, T. Tillman, 2022, Nature Communications.

Conformational Changes Underlying Desensitization of the Pentameric Ligand-Gated Ion Channel ELIC.

D. Mowrey, Yan Xu, P. Tang, 2015, Structure.

Common Anesthetic-binding Site for Inhibition of Pentameric Ligand-gated Ion Channels

R. Eckenhoff, Yan Xu, P. Tang, 2016, Anesthesiology.

ELIC-α7 Nicotinic Acetylcholine Receptor (α7nAChR) Chimeras Reveal a Prominent Role of the Extracellular-Transmembrane Domain Interface in Allosteric Modulation*

D. Mowrey, T. Tillman, E. Seyoum, 2014, The Journal of Biological Chemistry.

Anesthetic effects on the structure and dynamics of the second transmembrane domains of nAChR alpha4beta2.

Yan Xu, P. Tang, C. Canlas, 2010, Biochimica et biophysica acta.

X-Ray Crystallographic Studies for Revealing Binding Sites of General Anesthetics in Pentameric Ligand-Gated Ion Channels.

Yan Xu, P. Tang, Qiang Chen, 2018, Methods in enzymology.

Reversal of ion-charge selectivity renders the pentameric ligand-gated ion channel GLIC insensitive to anaesthetics.

Pei Tang, Qiang Chen, M. H. Cheng, 2013, The Biochemical journal.

Ensemble-based virtual screening for cannabinoid-like potentiators of the human glycine receptor α1 for the treatment of pain.

Pei Tang, David D Mowrey, D. Mowrey, 2015, Journal of medicinal chemistry.

19F Paramagnetic Relaxation-Based NMR for Quaternary Structural Restraints of Ion Channels.

V. Bondarenko, Yan Xu, P. Tang, 2019, ACS chemical biology.

Cellular Registration without Behavioral Recall of Olfactory Sensory Input under General Anesthesia

Pei Tang, Yan Xu, P. Tang, 2014, Anesthesiology.

Photoaffinity labeling the propofol binding site in GLIC.

R. Eckenhoff, D. C. Chiara, Jonathan B. Cohen, 2013, Biochemistry.

In silico models for the human alpha4beta2 nicotinic acetylcholine receptor.

M. H. Cheng, E. Haddadian, R. Coalson, 2008, The journal of physical chemistry. B.

Anesthetic modulation of protein dynamics: insight from an NMR study.

Yan Xu, P. Tang, Ling Li, 2008, The journal of physical chemistry. B.

NMR studies of a channel protein without membranes: Structure and dynamics of water-solubilized KcsA

Pei Tang, R. Eckenhoff, E. Meirovitch, 2008, Proceedings of the National Academy of Sciences.

Molecular dynamics simulations of a fully hydrated dimyristoylphosphatidylcholine membrane in liquid-crystalline phase

Yan Xu, P. Tang, M. Madrid, 2000 .

Different distribution of fluorinated anesthetics and nonanesthetics in model membrane: a 19F NMR study.

Yan Xu, P. Tang, Y. Xu, 1997, Biophysical journal.

Dependence of Early Cerebral Reperfusion and Long-Term Outcome on Resuscitation Efficiency After Cardiac Arrest in Rats

Yan Xu, P. Tang, S. Liachenko, 2002, Stroke.

Effects of Propofol General Anesthesia on Olfactory Relearning

Buwei Yu, Yan Xu, P. Tang, 2016, Scientific Reports.

A reproducible model of circulatory arrest and remote resuscitation in rats for NMR investigation.

Yan Xu, P. Tang, S. Liachenko, 1998, Stroke.

Four-alpha-helix bundle with designed anesthetic binding pockets. Part II: halothane effects on structure and dynamics.

J. Johansson, V. Bondarenko, Yan Xu, 2008, Biophysical journal.

Anesthetic interaction with ketosteroid isomerase: insights from molecular dynamics simulations.

Michael J. Yonkunas, Yan Xu, P. Tang, 2005, Biophysical journal.

Molecular dynamics simulations of C2F6 effects on gramicidin A: implications of the mechanisms of general anesthesia.

Yan Xu, P. Tang, Zhanwu Liu, 2005, Biophysical journal.

MD simulations of C2F6 effects on gramicidin A: Implication of mechanisms of general anesthesia

Yan Xu, P. Tang, Zhanwu Liu, 2005 .

Immune Modulation by Volatile Anesthetics

B. Lu, Yan Xu, P. Tang, 2016, Anesthesiology.

Common Anesthetic-binding Site for Inhibition of Pentameric Ligand-gated Ion Channels

R. Eckenhoff, Yan Xu, P. Tang, 2016, Anesthesiology.

A601 BRAIN ADC MAPPING AFTER RESUSCITATION FROM ASPHYXIAL CARDIAC ARREST

Yan Xu, P. Tang, S. Liachenko, 1997 .

Molecular dynamics simulations of ternary membrane mixture: phosphatidylcholine, phosphatidic acid, and cholesterol.

M. H. Cheng, Yan Xu, P. Tang, 2007, The journal of physical chemistry. B.

Photoaffinity labeling the propofol binding site in GLIC.

R. Eckenhoff, D. C. Chiara, Jonathan B. Cohen, 2014, Biochemistry.