M. Bauer

发表

One target-two different binding modes: structural insights into gevokizumab and canakinumab interactions to interleukin-1β.

Mathias Hafner, Michaela Blech, H. Nar, 2013, Journal of molecular biology.

Structural basis for inhibition promiscuity of dual specific thrombin and factor Xa blood coagulation inhibitors.

H. Nar, M. Bauer, J. Stassen, 2001, Structure.

The X-ray crystal structure of thrombin in complex with N alpha-2-naphthylsulfonyl-L-3-amidino-phenylalanyl-4-methylpiperidide: the beneficial effect of filling out an empty cavity.

H Brandstetter, W. Bode, H. Brandstetter, 1995, Journal of enzyme inhibition.

Biophysical and structural investigation of the regulation of human GTP Cyclohydrolase I by its regulatory protein GFRP.

Annie B. Kersting, H. Nar, S. Huber, 2020, Journal of structural biology.

X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B.

H Brandstetter, R. Huber, W. Bode, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis

J. King, H. Nar, M. Bauer, 2020, Proceedings of the National Academy of Sciences.

Crystal structure of human macrophage elastase (MMP-12) in complex with a hydroxamic acid inhibitor.

H. Nar, M. Bauer, H Dollinger, 2001, Journal of molecular biology.

The Three-dimensional Structure of Recombinant Leech-derived Tryptase Inhibitor in Complex with Trypsin

R. Huber, W. Bode, E. Auerswald, 1997, The Journal of Biological Chemistry.

Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin.

W. Bode, R. Huber, W. Bode, 1995, The EMBO journal.

Protein Production for Three-Dimensional Structural Analysis

M. Bauer, G. Schnapp, 2007 .

Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation.

A. Gils, H. Nar, P. Declerck, 2000, Journal of molecular biology.

Molecular structure of human GM-CSF in complex with a disease-associated anti-human GM-CSF autoantibody and its potential biological implications.

H. Nar, B. Kistler, M. Hafner, 2012, The Biochemical journal.

A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I

H. Nar, M. Bauer, M. Zeeb, 2020, Proceedings of the National Academy of Sciences.

Pharmacological characterization of the new bace1 inhibitor bi 1181181

S. Venkatraman, S. Hobson, M. Bauer, 2015, Alzheimer's & Dementia.

Crystallographic Evidence That the F2 Kringle Catalytic Domain Linker of Prothrombin Does Not Cover the Fibrinogen Recognition Exosite (*)

W. Bode, M. Stubbs, M. Bauer, 1996, Journal of Biological Chemistry.

Crystallization of Proteinases

M. Stubbs, M. Bauer, 1999 .

Discovery and Structure-Based Optimization of Fragments Binding the Mixed Lineage Kinase Domain-like Protein Executioner Domain.

J. King, H. Nar, M. Bauer, 2021, Journal of medicinal chemistry.

Sequential Backbone Assignment of Peroxisome Proliferator-Activated Receptor-γ Ligand Binding Domain

H. Kalbitzer, H. Nar, S. Kauschke, 2005, Journal of biomolecular NMR.

The 2.3 A crystal structure of the catalytic domain of recombinant two-chain human tissue-type plasminogen activator.

D Lamba, R. Huber, Stefan Fischer, 1996, Journal of molecular biology.

Crystallographic determination of thrombin complexes with small synthetic inhibitors as a starting point for the receptor-based design of antithrombotics.

D. Turk, W. Bode, H. Brandstetter, 1993, Seminars in thrombosis and hemostasis.

A hybrid screening approach for very small fragments - X-ray and Computational Screening on FKBP51.

H. Nar, M. Bauer, M. Zeeb, 2020, Journal of medicinal chemistry.

Crystal Structure of the Antihaemophilic Clotting Factor IXa

R. Huber, W. Bode, H. Brandstetter, 1996 .