Lauric Haber

High Affinity Antigen Recognition of the Dual Specific Variants of Herceptin Is Entropy-Driven in Spite of Structural Plasticity

R. Kelley, G. Fuh, J. Bostrom, 2011, PloS one.

A general method for greatly improving the affinity of antibodies by using combinatorial libraries.

Guido Cappuccilli, Richard A Lerner, Toshihiko Takeuchi, 2005, Proceedings of the National Academy of Sciences of the United States of America.

A class of costimulatory CD28-bispecific antibodies that enhance the antitumor activity of CD3-bispecific antibodies

L. Havel, C. Siao, A. Murphy, 2020, Science Translational Medicine.

Translational findings for odronextamab: From preclinical research to a first‐in‐human study in patients with CD20+ B‐cell malignancies

John D. Davis, M. Retter, Lauric Haber, 2022, Clinical and translational science.

A novel, native-format bispecific antibody triggering T-cell killing of B-cells is robustly active in mouse tumor models and cynomolgus monkeys

Andrew D. Tustian, Andrew D Tustian, G. Yancopoulos, 2015, Scientific Reports.

Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning

Jason T Giurleo, M. Retter, R. Tavaré, 2021, Scientific Reports.

A PSMA-Targeting CD3 Bispecific Antibody Induces Antitumor Responses that Are Enhanced by 4-1BB Costimulation

Jason T Giurleo, R. Tavaré, G. Thurston, 2020, Cancer Immunology Research.

Tumor-targeted CD28 bispecific antibodies enhance the antitumor efficacy of PD-1 immunotherapy

C. Siao, L. Macdonald, A. Murphy, 2020, Science Translational Medicine.

A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.

M. Sliwkowski, D. Danilenko, C. Eigenbrot, 2011, Cancer cell.

Improving antibody binding affinity and specificity for therapeutic development.

G. Fuh, J. Bostrom, Lauric Haber, 2009, Methods in molecular biology.

A Mucin 16 bispecific T cell–engaging antibody for the treatment of ovarian cancer

M. Retter, G. Thurston, P. Duramad, 2019, Science Translational Medicine.