J. Sohn

发表

Experimental validation of the docking orientation of Cdc25 with its Cdk2-CycA protein substrate.

Jerry M. Parks, H. Edelsbrunner, J. Rudolph, 2005, Biochemistry.

Catalytic and chemical competence of regulation of cdc25 phosphatase by oxidation/reduction.

J. Rudolph, J. Sohn, 2003, Biochemistry.

Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones.

M. Pirrung, J. Rudolph, A. Safi, 2003, Journal of medicinal chemistry.

Allostery Is an Intrinsic Property of the Protease Domain of DegS

R. Sauer, R. Grant, J. Sohn, 2010, The Journal of Biological Chemistry.

A pyrophosphatase-coupled assay to monitor the NTase activity of cGAS.

J. Sohn, R. Hooy, 2019, Methods in enzymology.

The DNA sensors AIM2 and IFI16 are SLE autoantigens that bind neutrophil extracellular traps

M. Petri, J. Sohn, Jessica Li, 2022, eLife.

The DNA sensors AIM2 and IFI16 are NET-binding SLE autoantigens

M. Petri, J. Sohn, Jessica Li, 2021, bioRxiv.

Tracking the polymerization of DNA sensors and inflammasomes using FRET.

J. Sohn, Zachary Mazanek, 2019, Methods in Enzymology.

IFI16 filament formation in salivary epithelial cells shapes the anti-IFI16 immune response in Sjögren's syndrome.

J. Sohn, A. Rosen, L. Casciola-Rosen, 2018, JCI insight.

Chromatin‐bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death

P. Sung, N. Gekara, J. Sohn, 2019, The EMBO journal.

Design principles for inflammasome inhibition by pyrin-only-proteins

J. Sohn, Archit Garg, Zachary Mazanek, 2022, bioRxiv.

The allosteric activation of cGAS underpins its dynamic signaling landscape

J. Sohn, R. Hooy, 2018, eLife.

Allosteric coupling between Mn2+ and dsDNA controls the catalytic efficiency and fidelity of cGAS

J. Sohn, R. Hooy, M. Chattergoon, 2020, Nucleic acids research.

Distinct axial and lateral interactions within homologous filaments dictate the signaling specificity and order of the AIM2-ASC inflammasome

E. Egelman, Weili Zheng, J. Sohn, 2021, Nature Communications.

Cryo-EM structure of the NLRC4CARD filament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly

E. Egelman, Weili Zheng, J. Sohn, 2018, The Journal of Biological Chemistry.

Filament assemblies in foreign nucleic acid sensors.

S. Hur, J. Sohn, 2016, Current opinion in structural biology.

The Cooperative Assembly of IFI16 Filaments on dsDNA Provides Insights into Host Defense Strategy

S. Morrone, J. Sohn, R. Hooy, 2015 .

Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy

S. Morrone, J. Sohn, Leeza Constantoulakis, 2013, Proceedings of the National Academy of Sciences.

Filament assembly underpins the double-stranded DNA specificity of AIM2-like receptors

J. Sohn, Archit Garg, Christina M. Stallings, 2023, Nucleic acids research.

Digital signaling network drives the assembly of the AIM2-ASC inflammasome

S. Morrone, J. Sohn, M. Matyszewski, 2018, Proceedings of the National Academy of Sciences.

Signal integration by DegS and RseB governs the σE-mediated envelope stress response in Escherichia coli

R. Sauer, C. Gross, Rachna Chaba, 2011, Proceedings of the National Academy of Sciences.

OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism.

R. Sauer, R. Grant, J. Sohn, 2009, Structure.

Allosteric Activation of DegS, a Stress Sensor PDZ Protease

R. Sauer, R. Grant, J. Sohn, 2007, Cell.

A conserved activation cluster is required for allosteric communication in HtrA-family proteases.

T. Baker, R. Sauer, R. Grant, 2015, Structure.

OMP peptides modulate the activity of DegS protease by differential binding to active and inactive conformations.

R. Sauer, J. Sohn, 2009, Molecular cell.

Association of Antibodies to Interferon‐Inducible Protein‐16 With Markers of More Severe Disease in Primary Sjögren's Syndrome

M. Petri, J. Sohn, A. Rosen, 2016, Arthritis care & research.

Cadenza ad libitum: cGAS and STING showcase their versatile virtuosities in the Ca2+-dependent rescue of stalled replication forks

J. Sohn, 2023, Molecular Cell.

Assembly-driven activation of the AIM2 foreign-dsDNA sensor provides a polymerization template for downstream ASC

E. Egelman, Xiong Yu, S. Morrone, 2015, Nature Communications.

Structural mechanism of oxidative regulation of the phosphatase Cdc25B via an intramolecular disulfide bond.

Carla Mattos, Jungsan Sohn, J. Rudolph, 2005, Biochemistry.

The innate immune sensor IFI16 recognizes foreign DNA in the nucleus by scanning along the duplex

Antoine M. van Oijen, A. V. van Oijen, S. Morrone, 2015, eLife.

Single-molecule imaging at high fluorophore concentrations by local activation of dye.

Antoine M. van Oijen, A. V. van Oijen, W. Mcgrath, 2015, Biophysical journal.

The energetic network of hotspot residues between Cdc25B phosphatase and its protein substrate.

J. Rudolph, J. Sohn, 2006, Journal of molecular biology.

Remote hot spots mediate protein substrate recognition for the Cdc25 phosphatase.

J. Rudolph, A. Safi, J. Sohn, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Temperature dependence of binding and catalysis for the Cdc25B phosphatase.

Jungsan Sohn, J. Rudolph, J. Sohn, 2007, Biophysical chemistry.

Helping Scholars Overcome Socioeconomic Barriers to Medical and Biomedical Careers: Creating a Pipeline Initiative

D. Robinson, J. Sohn, A. Wolfe, 2020, Teaching and learning in medicine.

OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism.

R. Sauer, R. Grant, J. Sohn, 2009, Structure.

The innate immune sensor IFI16 recognizes foreign DNA in the nucleus by scanning along the duplex

Antoine M. van Oijen, S. Morrone, J. Sohn, 2015, eLife.

Author response: The innate immune sensor IFI16 recognizes foreign DNA in the nucleus by scanning along the duplex

A. Oijen, S. Morrone, J. Sohn, 2015 .

Preparation of filamentous proteins for electron microscopy visualization and reconstruction.

J. Sohn, M. Matyszewski, 2019, Methods in enzymology.