M. Takimoto-Kamimura

发表

Major antigen-induced domain rearrangements in an antibody.

R L Stanfield, I. Wilson, R. Stanfield, 1993, Structure.

Structure of the β-form of human MK2 in complex with the non-selective kinase inhibitor TEI-L03090.

M. Takimoto-Kamimura, A. Fujino, K. Fukushima, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Drug Discovery Screening by Combination of X-ray Crystal Structure Analysis and FMO Calculation

N. Kurita, M. Takimoto-Kamimura, 2021 .

Structural development of non-secosteroidal vitamin D receptor (VDR) ligands without any asymmetric carbon.

M. Takimoto-Kamimura, Takashi Misawa, Y. Demizu, 2018, Bioorganic & medicinal chemistry.

New C15-substituted active vitamin D3.

M. Takimoto-Kamimura, D. Sawada, Nozomi Saito, 2011, Organic letters.

Design, synthesis and X-ray crystallographic study of new nonsecosteroidal vitamin D receptor ligands.

M. Takimoto-Kamimura, Y. Demizu, H. Okuda, 2011, Bioorganic & medicinal chemistry letters.

Structure of macrophage migration inhibitory factor in complex with methotrexate.

M. Takimoto-Kamimura, T. Kamimura, K. Fukushima, 2021, Acta crystallographica. Section D, Structural biology.

Mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2) as an antiinflammatory target: discovery and in vivo activity of selective pyrazolo[1,5-a]pyrimidine inhibitors using a focused library and structure-based optimization approach.

C. Harris, Kei Imaizumi, J. Frearson, 2012, Journal of medicinal chemistry.

C15-functionalized 16-ene-1α,25-dihydroxyvitamin D3 is a new vitamin D analog with unique biological properties.

M. Takimoto-Kamimura, Tai-Chi Chen, D. Sawada, 2012, Anticancer research.

The difference between 14-epi-previtamin D3 and 14-epi-19-norprevitamin D3: their synthesis and binding affinity for human VDR.

M. Takimoto-Kamimura, D. Sawada, Nozomi Saito, 2012, Anticancer research.

Crystal structure of a complex of human chymase with its benzimidazole derived inhibitor

T. Kawamura, M. Takimoto-Kamimura, M. Koizumi, 2013, Journal of synchrotron radiation.

Synthesis of 14-epi-2α-hydroxypropoxy-1α,25-dihydroxy-19-nortachysterol and its hVDR binding

M. Takimoto-Kamimura, D. Sawada, A. Kittaka, 2013, The Journal of Steroid Biochemistry and Molecular Biology.

Structure of the ligand-binding domain of rat VDR in complex with the nonsecosteroidal vitamin D3 analogue YR301.

W. Hakamata, K. Okada, M. Takimoto-Kamimura, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structure basis 1/2SLPI and porcine pancreas trypsin interaction

M. Takimoto-Kamimura, T. Kamimura, K. Fukushima, 2013, Journal of synchrotron radiation.

Diffraction Structural Biology Synchrotron Radiation Complex of Human Neutrophil Elastase with 1/2slpi

M. Takimoto-Kamimura, M. Koizumi, T. Kamimura, 2022 .

Structural analysis of an MK2-inhibitor complex: insight into the regulation of the secondary structure of the Gly-rich loop by TEI-I01800.

M. Takimoto-Kamimura, A. Fujino, K. Fukushima, 2010, Acta crystallographica. Section D, Biological crystallography.

Crystal structure of human cyclin-dependent kinase-2 complex with MK2 inhibitor TEI-I01800: insight into the selectivity

M. Takimoto-Kamimura, A. Fujino, K. Fukushima, 2013, Journal of synchrotron radiation.

Solvent Effect on Polymorphism in Crystallization of BPT Propyl Ester

M. Takimoto-Kamimura, M. Kitamura, T. Hara, 2006 .

Structural change of retinoic-acid receptor-related orphan receptor induced by binding of inverse-agonist: Molecular dynamics and ab initio molecular orbital simulations

Kentaro Kawai, N. Kurita, M. Takimoto-Kamimura, 2020, Computational and structural biotechnology journal.

Computer-aided de novo ligand design and docking/molecular dynamics study of Vitamin D receptor agonists

Midori Takimoto-Kamimura, M. Takimoto-Kamimura, Qingzhi Gao, 2011, Journal of Molecular Modeling.

Development of 14-epi-19-nortachysterol and its unprecedented binding configuration for the human vitamin D receptor.

M. Takimoto-Kamimura, D. Sawada, A. Kittaka, 2011, Journal of the American Chemical Society.

FMODB: The World's First Database of Quantum Mechanical Calculations for Biomacromolecules Based on the Fragment Molecular Orbital Method

Noriyuki Kurita, Kaori Fukuzawa, Tatsuya Takagi, 2021, J. Chem. Inf. Model..

Structural basis of the histidine-mediated vitamin D receptor agonistic and antagonistic mechanisms of (23S)-25-dehydro-1alpha-hydroxyvitamin D3-26,23-lactone.

A. Norman, M. Takimoto-Kamimura, H. Eguchi, 2010, Acta crystallographica. Section D, Biological crystallography.

Specific interactions between vitamin-D receptor and its ligands: Ab initio molecular orbital calculations in water

Kentaro Kawai, N. Kurita, M. Takimoto-Kamimura, 2017, The Journal of Steroid Biochemistry and Molecular Biology.

24,24-Dimethylvitamin D3-26,23-lactones and their 2α-functionalized analogues as highly potent VDR antagonists ☆

M. Takimoto-Kamimura, Nozomi Saito, A. Kittaka, 2004 .

Molecular dynamics and ab initio FMO calculations on the effect of water molecules on the interactions between androgen receptor and its ligand and cofactor

Kentaro Kawai, N. Kurita, M. Takimoto-Kamimura, 2016, 2016 International Conference On Advanced Informatics: Concepts, Theory And Application (ICAICTA).

Proposal of novel inhibitors for vitamin-D receptor: Molecular docking, molecular mechanics and ab initio molecular orbital simulations.

N. Kurita, M. Takimoto-Kamimura, A. Kittaka, 2021, Biophysical chemistry.

Proposal of potent inhibitors for vitamin-D receptor based on ab initio fragment molecular orbital calculations.

Kentaro Kawai, N. Kurita, M. Takimoto-Kamimura, 2018, Journal of molecular graphics & modelling.

Synthesis of novel C-2 substituted vitamin D derivatives having ringed side chains and their biological evaluation on bone

Y. Harada, M. Takimoto-Kamimura, A. Kittaka, 2013, The Journal of Steroid Biochemistry and Molecular Biology.

Effects of 2-substitution on 14-epi-19-nortachysterol-mediated biological events: based on synthesis and X-ray co-crystallographic analysis with the human vitamin D receptor.

M. Takimoto-Kamimura, D. Sawada, A. Kittaka, 2018, Organic & biomolecular chemistry.

Synthesis of 2α-heteroarylalkyl active vitamin d3 with therapeutic effect on enhancing bone mineral density in vivo.

Y. Harada, M. Takimoto-Kamimura, D. Sawada, 2013, ACS medicinal chemistry letters.

Structure of N‐γ‐l‐glutamyl‐l‐cysteine ethyl ester monohydrate

M. Takimoto-Kamimura, K. Fujii, K. Koyano, 1990 .

Synthesis of 24,24-Ethanovitamin D3 Lactones Using Ruthenium-Catalyzed Intermolecular Enyne Metathesis: Potent Vitamin D Receptor Antagonists

M. Takimoto-Kamimura, Nozomi Saito, A. Kittaka, 2005 .

Dimer and superstructure of the active form of a vitamin D3; 1 alpha,24(R)dihydroxy-vitamin D3 monohydrate, C27O3H44.H2O.

M. Takimoto-Kamimura, K. Koyano, Y. Saitoh, 2001, Chemical & pharmaceutical bulletin.

Water molecule-mediated selective inhibition of bacterial zinc metalloproteinases by non-hydroxamate compounds: Ab initio molecular simulations.

N. Kurita, M. Takimoto-Kamimura, Kyohei Imai, 2022, Journal of molecular graphics & modelling.

Specific interactions between vitamin D receptor and ligand depending on its chirality: ab initio fragment molecular orbital calculations

Kentaro Kawai, N. Kurita, M. Takimoto-Kamimura, 2018 .