A. Steward

发表

Single-molecule fluorescence reveals sequence-specific misfolding in multidomain proteins

Jane Clarke, Robert B. Best, Annette Steward, 2011, Nature.

Folding pathway of an Ig domain is conserved on and off the ribosome

G. von Heijne, J. Clarke, R. Best, 2018, Proceedings of the National Academy of Sciences.

The Folding Pathway of an Ig Domain is Conserved On and Off the Ribosome

G. Heijne, J. Clarke, R. Best, 2018, bioRxiv.

Investigating the Effect of Chain Connectivity on the Folding of a Beta-Sheet Protein On and Off the Ribosome

J. Clarke, J. Hollins, A. Steward, 2018, Journal of molecular biology.

Investigating the Effect of Chain Connectivity on the Folding of a Beta-Sheet Protein On and Off the Ribosome

J. Clarke, J. Hollins, A. Steward, 2018, Journal of molecular biology.

Staphylococcal biofilm-forming protein has a contiguous rod-like structure

J. Clarke, R. Bingham, A. Leech, 2012, Proceedings of the National Academy of Sciences.

Understanding pathogenic single-nucleotide polymorphisms in multidomain proteins – studies of isolated domains are not enough

J. Clarke, L. G. Randles, Adrian A. Nickson, 2013, The FEBS journal.

Mechanical unfolding of TNfn3: the unfolding pathway of a fnIII domain probed by protein engineering, AFM and MD simulation.

E. Paci, J. Clarke, A. Steward, 2005, Journal of molecular biology.

Hidden complexity in the mechanical properties of titin

Jane Clarke, Robert B. Best, Annette Steward, 2003, Nature.

Chromatin accessibility dynamics across C. elegans development and ageing

J. Ahringer, S. Sauer, A. Appert, 2018, bioRxiv.

Chromatin accessibility is dynamically regulated across C. elegans development and ageing

J. Ahringer, A. Appert, P. Stempor, 2018, bioRxiv.

Evolution of oligomeric state through allosteric pathways that mimic ligand binding

Sarah A. Teichmann, Jane Clarke, Nathalie Reuter, 2014, Science.

Comparative assessment of fluorescent proteins for in vivo imaging in an animal model system

J. Ahringer, D. Dickinson, B. Goldstein, 2016, bioRxiv.

The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology.

J. Clarke, S. J. Hamill, A. Steward, 2000, Journal of molecular biology.

Titin; a multidomain protein that behaves as the sum of its parts.

J. Clarke, Kathryn A. Scott, S. Fowler, 2002, Journal of molecular biology.

Cotranslational folding of spectrin domains via partially structured states

G. von Heijne, J. Clarke, R. Beckmann, 2017, Nature Structural &Molecular Biology.

Self-consistent determination of the transition state for protein folding: Application to a fibronectin type III domain

M. Karplus, E. Paci, M. Vendruscolo, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Sequence conservation in Ig-like domains: the role of highly conserved proline residues in the fibronectin type III superfamily.

J. Clarke, A. Steward, S. Adhya, 2002, Journal of molecular biology.

The folding nucleus of a fibronectin type III domain is composed of core residues of the immunoglobulin-like fold.

E. Cota, J. Clarke, S. Fowler, 2001, Journal of molecular biology.

Mechanical unfolding of a titin Ig domain: structure of unfolding intermediate revealed by combining AFM, molecular dynamics simulations, NMR and protein engineering.

Jane Clarke, Robert B Best, Emanuele Paci, 2002, Journal of molecular biology.

Two Immunoglobulin Tandem Proteins with a Linking β-Strand Reveal Unexpected Differences in Cooperativity and Folding Pathways

J. Clarke, J. M. Rogers, M. Wilmanns, 2012, Journal of molecular biology.

Experimental evidence for a frustrated energy landscape in a 3-helix bundle protein family

Jane Clarke, Annette Steward, Sarah Batey, 2009, Nature.

The folding and unfolding behavior of ribonuclease H on the ribosome

S. Marqusee, J. Clarke, A. Steward, 2020, The Journal of Biological Chemistry.

Distinguishing specific and nonspecific interdomain interactions in multidomain proteins.

J. Clarke, L. G. Randles, Sarah Batey, 2008, Biophysical journal.

Cooperative folding in a multi-domain protein.

J. Clarke, L. G. Randles, Sarah Batey, 2005, Journal of molecular biology.

Mechanical unfolding of a titin Ig domain: structure of transition state revealed by combining atomic force microscopy, protein engineering and molecular dynamics simulations.

E. Paci, J. Clarke, R. Best, 2003, Journal of molecular biology.

Can non-mechanical proteins withstand force? Stretching barnase by atomic force microscopy and molecular dynamics simulation.

V. Daggett, J. Clarke, R. Best, 2001, Biophysical journal.

An Effective Strategy for the Design of Proteins with Enhanced Mechanical Stability**

Alessandro Borgia, J. Clarke, A. Steward, 2008, Angewandte Chemie.

Versatile cloning system for construction of multimeric proteins for use in atomic force microscopy

J. Toca-Herrera, J. Clarke, A. Steward, 2002, Protein science : a publication of the Protein Society.

Thermodynamic characterisation of two transition states along parallel protein folding pathways.

J. Clarke, C. Wright, A. Steward, 2004, Journal of molecular biology.

Folding and Binding of an Intrinsically Disordered Protein: Fast, but Not ‘Diffusion-Limited’

Jane Clarke, Annette Steward, J. Clarke, 2013, Journal of the American Chemical Society.

Topology is the Principal Determinant in the Folding of a Complex All-alpha Greek Key Death Domain from Human FADD

Jane Clarke, Gary S. McDowell, Annette Steward, 2009, Journal of molecular biology.