M. Gelin

发表

In-plate protein crystallization, in situ ligand soaking and X-ray diffraction.

G. Labesse, S. Pochet, J. Ferrer, 2011, Acta crystallographica. Section D, Biological crystallography.

Combining 'dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography.

G. Labesse, J. Ferrer, F. Hoh, 2015, Acta crystallographica. Section D, Biological crystallography.

Toward the Design of Ligands Selective for the C-Terminal Domain of TEADs.

F. Allemand, M. Gelin, J. Guichou, 2022, Journal of medicinal chemistry.

Discovery of a cryptic site at the interface 2 of TEAD - Towards a new family of YAP/TAZ-TEAD inhibitors.

X. Thuru, F. Bailly, F. Allemand, 2021, European journal of medicinal chemistry.

Characterization of the Anti-Hepatitis C Virus Activity of New Nonpeptidic Small-Molecule Cyclophilin Inhibitors with the Potential for Broad Anti-Flaviviridae Activity

J. Pawlotsky, N. Jouvenet, P. Bruscella, 2018, Antimicrobial Agents and Chemotherapy.

A NEW APPROACH TO A DISACCHARIDIC HAPTEN CONTAINING A GALACTOFURANOSYL ENTITY1-2

V. Ferrières, D. Plusquellec, M. Gelin, 2001 .

A convenient synthesis of disaccharides containing furanoside units

T. Benvegnu, D. Plusquellec, M. Gelin, 1997 .

Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation.

G. Labesse, G. Hoxhaj, C. Lionne, 2022, Molecular cell.

Dimerization of the Pragmin pseudo-kinase regulates protein tyrosine phosphorylation

G. Labesse, J. Pons, S. Urbach, 2017, bioRxiv.

Small-molecule inhibitors of cyclophilins block opening of the mitochondrial 1 permeability transition pore and protect mice from hepatic ischemia – reperfusion injury 2 3

Jean-François, J. Pawlotsky, J. Calderaro, 2022 .

An efficient route to per- O -acetylated hexofuranoses

V. Ferrières, D. Plusquellec, M. Gelin, 1998 .

Screening and in situ synthesis using crystals of a NAD kinase lead to a potent antistaphylococcal compound.

G. Labesse, S. Pochet, L. Dugué, 2012, Structure.

First Intramolecular Aglycon Delivery onto a D‐Fucofuranosyl Entity for the Synthesis of α‐D‐Fucofuranose‐Containing Disaccharides

V. Ferrières, D. Plusquellec, M. Gelin, 2003 .

A General and Diastereoselective Synthesis of 1,2-cis-Hexofuranosides from 1,2-trans-Thiofuranosyl Donors

V. Ferrières, D. Plusquellec, M. Gelin, 2000 .

Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.

G. Labesse, S. Pochet, J. Pons, 2022, European journal of medicinal chemistry.

8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode.

G. Labesse, S. Pochet, M. Nahori, 2016, European journal of medicinal chemistry.

Small-molecule inhibitors of cyclophilins block opening of the mitochondrial permeability transition pore and protect mice from hepatic ischemia-reperfusion injury.

J. Pawlotsky, J. Calderaro, F. Allemand, 2019, Gastroenterology.

Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities

J. Pawlotsky, D. Douguet, W. Bourguet, 2016, Nature Communications.

Effect of bombesin on gastric secretion and motility in the cat.

T. McDonald, M. Vagne, M. Gelin, 1982, Digestion.

Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding.

G. Labesse, J. Pons, W. Bourguet, 2021, Journal of medicinal chemistry.

New Chemical Probe Targeting Bacterial NAD Kinase

G. Labesse, S. Pochet, C. Lionne, 2020, Molecules.

From substrate to fragments to inhibitor active in vivo against Staphylococcus aureus.

G. Labesse, S. Pochet, L. Dugué, 2020, ACS infectious diseases.

Structure‐based design, synthesis and biological evaluation of a NAD + analogue targeting Pseudomonas aeruginosa NAD kinase

G. Labesse, S. Pochet, C. Lionne, 2022, The FEBS journal.

Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation.

G. Labesse, J. Pons, S. Urbach, 2018, Structure.

First-in-class allosteric inhibitors of bacterial IMPDHs.

G. Labesse, H. Munier-Lehmann, L. Dugué, 2019, European journal of medicinal chemistry.

Crystallographic studies of two variants of Pseudomonas aeruginosa IMPDH with impaired allosteric regulation.

G. Labesse, H. Munier-Lehmann, A. Haouz, 2015, Acta crystallographica. Section D, Biological crystallography.

Effect of cholecystokinin and pentagastrin on motility and gastric secretion in the cat.

M. Vagne, M. Gelin, M. Roche, 1980, Digestion.

ROP2 from Toxoplasma gondii: a virulence factor with a protein-kinase fold and no enzymatic activity.

G. Labesse, S. Arold, J. Dubremetz, 2008, Structure.

Kinetic study of the interaction between rat haptoglobin and rat liver cathepsin B.

M. Pagano, M. Gelin, M. Jayle, 1980, Canadian journal of biochemistry.

Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases

G. Labesse, H. Munier-Lehmann, B. Raynal, 2023, Protein science : a publication of the Protein Society.

A General and Diastereoselective Synthesis of 1,2-cis-Hexofuranosides from 1,2-trans-Thiofuranosyl Donors.

V. Ferrières, D. Plusquellec, M. Gelin, 2001 .

wTSA-CRAFT: an open-access web server for rapid analysis of thermal shift assay experiments

C. Lionne, M. Gelin, Victor Reys, 2023, bioRxiv.