W. Rypniewski

发表

Crystals of cytochrome c‐553 from Bacillus pasteurii show diffraction to 0.97 å resolution

K. Wilson, S. Ciurli, S. Benini, 1997, Proteins.

Crystallization and preliminary X-ray diffraction studies of a toxic phospholipase A2 from the venom of Vipera ammodytes meridionalis complexed to a synthetic inhibitor.

M. Perbandt, C. Betzel, Mahendra K. Jain, 2003, Biochimica et biophysica acta.

The 10.8-A structure of Saccharomyces cerevisiae phosphofructokinase determined by cryoelectron microscopy: localization of the putative fructose 6-phosphate binding sites.

M. Radermacher, W. Rypniewski, G. Kopperschläger, 2003, Journal of structural biology.

Crystallographic characterization of CCG repeats

R. Kierzek, W. Krzyzosiak, W. Rypniewski, 2012, Nucleic acids research.

Structural insights into CUG repeats containing the ‘stretched U–U wobble’: implications for myotonic dystrophy

R. Kierzek, W. Krzyzosiak, W. Rypniewski, 2009, Nucleic acids research.

Structural studies of CNG repeats

W. Rypniewski, A. Kiliszek, 2014, Nucleic acids research.

Structure-based rationalization of urease inhibition by phosphate: novel insights into the enzyme mechanism

K. Wilson, S. Ciurli, S. Mangani, 2001, JBIC Journal of Biological Inorganic Chemistry.

Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS.

S. Filipek, P. Maj, A. Bronowska, 2017, Journal of molecular graphics & modelling.

Structural consequences of reductive methylation of lysine residues in hen egg white lysozyme: an X-ray analysis at 1.8-A resolution.

I. Rayment, H. Holden, W. Rypniewski, 1993 .

Molecular details of urease inhibition by boric acid: insights into the catalytic mechanism.

K. Wilson, S. Ciurli, S. Mangani, 2004, Journal of the American Chemical Society.

Mouse thymidylate synthase does not show the inactive conformation, observed for the human enzyme

W. Rypniewski, P. Wilk, T. Frączyk, 2017, Structural Chemistry.

Crystal structures of complexes of mouse thymidylate synthase crystallized with N4-OH-dCMP alone or in the presence of N5,10-methylenetetrahydrofolate

W. Rypniewski, B. Kierdaszuk, P. Wilk, 2013 .

Noncanonical G(syn)-G(anti) base pairs stabilized by sulphate anions in two X-ray structures of the (GUGGUCUGAUGAGGCC) RNA duplex.

R. Adamiak, W. Rypniewski, J. Milecki, 2008, RNA.

The mistletoe lectin I--phloretamide structure reveals a new function of plant lectins.

J. Barciszewski, C. Betzel, V. Erdmann, 2007, Biochemical and biophysical research communications.

Crystal structures of substrate-bound chitinase from the psychrophilic bacterium Moritella marina and its structure in solution.

D. Svergun, M. Petoukhov, C. Vorgias, 2014, Acta crystallographica. Section D, Biological crystallography.

Design, Synthesis, and Evaluation of Novel 3-Carboranyl-1,8-Naphthalimide Derivatives as Potential Anticancer Agents

M. Giel-Pietraszuk, A. Bąk, W. Rypniewski, 2021, International journal of molecular sciences.

Exploring structural determinants and the role of nucleolin in formation of the long-range interactions between untranslated regions of p53 mRNA

W. Rypniewski, A. Kiliszek, L. Błaszczyk, 2022, bioRxiv.

Crystallization and Structure Determination to 2 . 581 Resolution of the Oxidized [ 2 Fe2 SI Ferredoxin Isolated from Anabaena 7 120 t

B. Oh, I. Rayment, J. Markley, 2001 .

Engineering N-(2-pyridyl)aminoethyl alcohols as potential precursors of thermolabile protecting groups

M. Chmielewski, W. Rypniewski, W. Markiewicz, 2012 .

The hydration and unusual hydrogen bonding in the crystal structure of an RNA duplex containing alternating CG base pairs

R. Adamiak, W. Rypniewski, J. Milecki, 2010 .

The complex of Bacillus pasteurii urease with acetohydroxamate anion from X-ray data at 1.55 Å resolution

K. Wilson, S. Ciurli, S. Mangani, 2000, JBIC Journal of Biological Inorganic Chemistry.

RNA duplex anions in two X-ray structures of the ( GUGGUCUGAUGAGGCC ) Noncanonical G ( syn )-G ( anti ) base pairs stabilized by sulphate data

R. Adamiak, W. Rypniewski, J. Milecki, 2022 .

Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)–G(syn) pair

W. Rypniewski, A. Kiliszek, Martyna Pluta, 2022, bioRxiv.

Crystallization and preliminary X-ray analysis of the isomerase domain of glucosamine-6-phosphate synthase from Candida albicans.

R. Jedrzejczak, W. Rypniewski, S. Milewski, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Preliminary X-ray diffraction studies of the external functional unit RtH2-e from the Rapana thomasiana.

M. Perbandt, C. Betzel, W. Rypniewski, 2001, Acta crystallographica. Section D, Biological crystallography.

Crystallization, preliminary X-ray analysis and amino acid sequence studies of an “external” functional unit from the Rapana thomasiana grosse (mollusc, gastropod) hemocyanin

M. Perbandt, C. Betzel, W. Rypniewski, 2001 .

Crystal structure of unliganded phosphofructokinase from Escherichia coli.

P. Evans, W. Rypniewski, 1989, Journal of molecular biology.

The structure of a functional unit from the wall of a gastropod hemocyanin offers a possible mechanism for cooperativity.

M. Perbandt, C. Betzel, E. Guthöhrlein, 2003, Biochemistry.

Design of DNA Intercalators Based on 4-Carboranyl-1,8-Naphthalimides: Investigation of Their DNA-Binding Ability and Anticancer Activity

M. Giel-Pietraszuk, W. Rypniewski, A. Kowalczyk, 2022, International journal of molecular sciences.

Synthetic human prion protein octapeptide repeat binds to the proteinase K active site.

M. Perbandt, C. Betzel, L. Redecke, 2004, Biochemical and biophysical research communications.

Structural, Thermodynamic and Enzymatic Characterization of N,N-Diacetylchitobiose Deacetylase from Pyrococcus chitonophagus

D. Svergun, W. Rypniewski, D. Baranowski, 2022, International journal of molecular sciences.

A new proposal for urease mechanism based on the crystal structures of the native and inhibited enzyme from Bacillus pasteurii: why urea hydrolysis costs two nickels.

K. Wilson, S. Ciurli, S. Mangani, 1999, Structure.

Spider Chitin: An Ultrafast Microwave-Assisted Method for Chitin Isolation from Caribena versicolor Spider Molt Cuticle

S. Bornstein, H. Ehrlich, O. Pokrovsky, 2019, Molecules.

The complex of Bacillus pasteurii urease with β-mercaptoethanol from X-ray data at 1.65-Å resolution

K. Wilson, S. Ciurli, S. Mangani, 1998, JBIC Journal of Biological Inorganic Chemistry.

Crystallization and preliminary high-resolution X-ray diffraction analysis of native and beta-mercaptoethanol-inhibited urease from Bacillus pasteurii.

S Mangani, K S Wilson, K. Wilson, 1998, Acta crystallographica. Section D, Biological crystallography.

Structural properties of the nickel ions in urease: novel insights into the catalytic and inhibition mechanisms

K. Wilson, S. Ciurli, S. Mangani, 1999 .

Novel Isoniazid-Carborane Hybrids Active In Vitro against Mycobacterium tuberculosis

J. Dziadek, M. Korycka-Machala, W. Rypniewski, 2020, Pharmaceuticals.

Crystal structure of reduced bovine erythrocyte superoxide dismutase at 1.9 A resolution.

K. Wilson, S. Mangani, W. Rypniewski, 1995, Journal of molecular biology.

Carboranyl-1,8-naphthalimide intercalators induce lysosomal membrane permeabilization and ferroptosis in cancer cell lines

W. Rypniewski, A. Kowalczyk, P. Stączek, 2023, Journal of enzyme inhibition and medicinal chemistry.

Helix-loop-helix peptide foldamers and their use in the construction of hydrolase mimetics.

Jakub M. Tomczak, W. Rypniewski, K. Ożga, 2018, Bioorganic chemistry.

Synthesis of naphthalimide-carborane and metallacarborane conjugates: Anticancer activity, DNA binding ability.

M. Giel-Pietraszuk, W. Rypniewski, A. Kiliszek, 2019, Bioorganic chemistry.

A computationally designed β-amino acid-containing miniprotein.

W. Rypniewski, Łukasz Berlicki, Jacek Plewka, 2021, Chemical communications.

Selectivity of Ni(II) and Zn(II) binding to Sporosarcina pasteurii UreE, a metallochaperone in the urease assembly: a calorimetric and crystallographic study

S. Ciurli, W. Rypniewski, B. Zambelli, 2013, JBIC Journal of Biological Inorganic Chemistry.

The crystal and solution studies of glucosamine-6-phosphate synthase from Candida albicans.

D. Svergun, W. Rypniewski, S. Milewski, 2007, Journal of molecular biology.

Plant growth promoting N-alkyltropinium bromides enhance seed germination, biomass accumulation and photosynthesis parameters of maize (Zea mays)

K. Myszka, W. Rypniewski, Ł. Chrzanowski, 2019, New Journal of Chemistry.

Analysis of the complete genome sequence of the archaeon Pyrococcus chitonophagus DSM 10152 (formerly Thermococcus chitonophagus)

M. Engel, M. Schloter, J. Blom, 2016, Extremophiles.

Evolutionary divergence and conservation of trypsin.

K S Wilson, A Perrakis, K. Wilson, 1994, Protein engineering.

Broken symmetry between RNA enantiomers in a crystal lattice

W. Rypniewski, A. Kiliszek, L. Błaszczyk, 2021, Nucleic acids research.

Three-dimensional structure of myosin subfragment-1: a molecular motor.

D A Winkelmann, H M Holden, I. Rayment, 1993, Science.

Crystal structure of 2'-O-Me(CGCGCG)2, an RNA duplex at 1.30 A resolution. Hydration pattern of 2'-O-methylated RNA.

R. Adamiak, Z. Dauter, M. Popenda, 1997, Nucleic acids research.

Molecular Mechanism of Thymidylate Synthase Inhibition by N4-Hydroxy-dCMP in View of Spectrophotometric and Crystallographic Studies

A. Bzowska, P. Maj, W. Rypniewski, 2021, International journal of molecular sciences.

Crystal structures of thymidylate synthase from nematodes, Trichinella spiralis and Caenorhabditis elegans, as a potential template for species-specific drug design

W. Rypniewski, P. Wilk, T. Frączyk, 2013 .

Nucleoside bearing boron clusters and their phosphoramidites – building blocks for modified oligonucleotide synthesis

W. Rypniewski, A. Kiliszek, Z. Leśnikowski, 2015 .

The 1.19 A X-ray structure of 2'-O-Me(CGCGCG)(2) duplex shows dehydrated RNA with 2-methyl-2,4-pentanediol in the minor groove.

R. Adamiak, W. Rypniewski, J. Milecki, 2001, Nucleic acids research.

The molecular structure of insecticyanin from the tobacco hornworm Manduca sexta L. at 2.6 A resolution.

I. Rayment, J. H. Law, H. Holden, 1987, The EMBO journal.

Structure of inhibited trypsin from Fusarium oxysporum at 1.55 A.

K. Wilson, W. Rypniewski, C. Dambmann, 1995, Acta crystallographica. Section D, Biological crystallography.

Crystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndrome

R. Kierzek, W. Krzyzosiak, W. Rypniewski, 2011, Nucleic acids research.

Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseases

Wlodzimierz J. Krzyzosiak, R. Kierzek, W. Krzyzosiak, 2010, Nucleic acids research.

First look at RNA in L-configuration.

M. Vallazza, M. Perbandt, C. Betzel, 2004, Acta crystallographica. Section D, Biological crystallography.

The crystal structures of eukaryotic phosphofructokinases from baker's yeast and rabbit skeletal muscle.

M. Radermacher, G. Obmolova, W. Rypniewski, 2011, Journal of molecular biology.

High-resolution native and complex structures of thermostable beta-mannanase from Thermomonospora fusca - substrate specificity in glycosyl hydrolase family 5.

W. Zimmermann, K. Piontek, S. Gloor, 1998, Structure.

The first crystal structure of an RNA racemate.

M. Vallazza, M. Perbandt, L. DeLucas, 2006, Acta crystallographica. Section D, Biological crystallography.

Comparative crystallization and preliminary X-ray diffraction studies of locked nucleic acid and RNA stems of a tenascin C-binding aptamer.

M. Perbandt, C. Betzel, V. Erdmann, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural insights into synthetic ligands targeting A–A pairs in disease-related CAG RNA repeats

R. Micura, C. Dohno, K. Nakatani, 2019, Nucleic acids research.

Crystallographic and X-ray absorption spectroscopic characterization of Helicobacter pylori UreE bound to Ni²⁺ and Zn²⁺ reveals a role for the disordered C-terminal arm in metal trafficking.

S. Ciurli, W. Rypniewski, B. Zambelli, 2012, The Biochemical journal.

High-resolution X-ray structure of the DNA-binding protein HU from the hyper-thermophilic Thermotoga maritima and the determinants of its thermostability

C. Vorgias, E. Christodoulou, W. Rypniewski, 2003, Extremophiles.

Asp49 phospholipase A(2)-elaidoylamide complex: a new mode of inhibition.

C. Betzel, W. Rypniewski, D. Georgieva, 2004, Biochemical and biophysical research communications.

Structures of RNA repeats associated with neurological diseases

W. Rypniewski, A. Kiliszek, L. Błaszczyk, 2017, Wiley interdisciplinary reviews. RNA.

Structural consequences of reductive methylation of lysine residues in hen egg white lysozyme: an X-ray analysis at 1.8-A resolution.

I. Rayment, H. Holden, W. Rypniewski, 1993, Biochemistry.

Fusarium oxysporum trypsin at atomic resolution at 100 and 283 K: a study of ligand binding.

K. Wilson, W. Rypniewski, P. Ostergaard, 2001, Acta crystallographica. Section D, Biological crystallography.

X-ray Crystal and Ab Initio Structures of 3′,5′-di-O-Acetyl-N(4)-Hydroxy-2′-Deoxycytidine and Its 5-Fluoro Analogue: Models of the N(4)-OH-dCMP and N(4)-OH-FdCMP Molecules Interacting with Thymidylate Synthase

W. Rypniewski, K. Felczak, W. Rode, 2005 .

Watson–Crick-like pairs in CCUG repeats: evidence for tautomeric shifts or protonation

T. Kulinski, W. Rypniewski, A. Kiliszek, 2016, RNA.

Structure of mistletoe lectin I from Viscum album in complex with the phytohormone zeatin.

J. Barciszewski, C. Betzel, A. Meyer, 2008, Biochimica et biophysica acta.

The crystal structure of the monomeric human SOD mutant F50E/G51E/E133Q at atomic resolution. The enzyme mechanism revisited.

M. Ferraroni, I. Bertini, K. Wilson, 1999, Journal of molecular biology.

Structure of a complete four-domain chitinase from Moritella marina, a marine psychrophilic bacterium.

C. Vorgias, W. Rypniewski, P. Małecki, 2013, Acta crystallographica. Section D, Biological crystallography.

Trypsin Revisited

Andrea Schmidt, Christian Jelsch, Victor S. Lamzin, 2003, Journal of Biological Chemistry.

The Crystal Structure of a Streptomyces thermoviolaceus Thermophilic Chitinase Known for Its Refolding Efficiency

C. Vorgias, W. Rypniewski, P. Małecki, 2020, International journal of molecular sciences.

The stability of the TIM-barrel domain of a psychrophilic chitinase

C. Vorgias, W. Rypniewski, M. Theodoridou, 2015, Biochemistry and biophysics reports.

Crystallographic determination of reduced bovine superoxide dismutase at pH 5.0 and of anion binding to its active site

Bruno Bruni, M. Ferraroni, S. Mangani, 1998, JBIC Journal of Biological Inorganic Chemistry.

X-ray, NMR and molecular dynamics studies on reduced bovine superoxide dismutase: implications for the mechanism.

I. Bertini, C. Luchinat, P. Carloni, 1994, Biochemical and Biophysical Research Communications - BBRC.

High resolution crystal structure of Rubrivivax gelatinosus cytochrome c'.

K. Wilson, S. Ciurli, S. Benini, 2008, Journal of inorganic biochemistry.

Crystal structure of oxidized Bacillus pasteurii cytochrome c553 at 0.97-A resolution.

Keith S. Wilson, Stefano Ciurli, J. V. Van Beeumen, 2000, Biochemistry.

The first crystal structures of RNA–PNA duplexes and a PNA-PNA duplex containing mismatches—toward anti-sense therapy against TREDs

Z. Dauter, W. Rypniewski, A. Kiliszek, 2015, Nucleic acids research.

The sequence and X-ray structure of the trypsin from Fusarium oxysporum.

C. Betzel, Z. Dauter, S. Hastrup, 1993, Protein engineering.

Oxyonium phosphobetaines – unusually stable nucleophilic catalyst–phosphate complexes formed from H-phosphonates and N-oxides

W. Rypniewski, A. Kiliszek, J. Stawinski, 2016 .

Stabilization of RNA hairpins using non-nucleotide linkers and circularization

R. Kierzek, W. Rypniewski, A. Kiliszek, 2017, Nucleic acids research.

Crystal structure of phosphoramide-phosphorylated thymidylate synthase reveals pSer127, reflecting probably pHis to pSer phosphotransfer.

W. Rypniewski, T. Ruman, P. Wilk, 2014, Bioorganic chemistry.

Studies on synthesis and structure of O-beta-D-ribofuranosyl(1"-->2')ribonucleosides and oligonucleotides.

Z. Dauter, M. Chmielewski, W. Rypniewski, 1998, Nucleosides & nucleotides.

Crystallization and preliminary X-ray diffraction analysis of cytochrome c' from Rubrivivax gelatinosus at 1.3 A resolution.

K. Wilson, S. Ciurli, S. Benini, 1998, Acta crystallographica. Section D, Biological crystallography.

Crystallographic analysis of a thermoactive nitrilase.

Garabed Antranikian, Joanna E Raczynska, C. Vorgias, 2011, Journal of structural biology.

Structural insights into CUG repeats containing the 'stretched U-U wobble': implications for myotonic dystrophy.

R. Kierzek, W. Krzyzosiak, W. Rypniewski, 2009, Nucleic acids research.

Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties.

W. Rypniewski, A. Kiliszek, S. Milewski, 2019, Journal of structural biology.

Analysis of the complete genome sequence of the archaeon Pyrococcus chitonophagus DSM 10152 (formerly Thermococcus chitonophagus)

M. Engel, M. Schloter, J. Blom, 2016, Extremophiles.

Crystallization and structure determination to 2.5-A resolution of the oxidized [2Fe-2S] ferredoxin isolated from Anabaena 7120.

B. Oh, I. Rayment, H. Holden, 1991 .

The crystal structures of eukaryotic phosphofructokinases from baker's yeast and rabbit skeletal muscle.

M. Radermacher, G. Obmolova, W. Rypniewski, 2011, Journal of molecular biology.

The crystal structure of the reduced disulphide bond isomerase, DsbC, from Escherichia coli

W. Rypniewski, I. Mechin, K. Banaszak, 2004 .

Binding of the plant hormone kinetin in the active site of Mistletoe Lectin I from Viscum album.

J. Barciszewski, A. Meyer, W. Rypniewski, 2012, Biochimica et biophysica acta.

CRYSTALLOGRAPHY AT (SUB) ATOMIC RESOLUTION AND QUANTUM CHEMISTRY REVEALING DETAILS OF CATALYSIS

A. Schmidt, P. Østergaard, V. Lamzin, 2003 .