M. Bowler

发表

Improving diffraction by humidity control: a novel device compatible with X-ray beamlines.

Florent Cipriani, Matthew W Bowler, Bernard Lavault, 2009, Acta crystallographica. Section D, Biological crystallography.

Direct cryocooling of naked crystals: are cryoprotection agents always necessary?

M. Bowler, E. Pellegrini, D. Piano, 2011, Acta crystallographica. Section D, Biological crystallography.

Inducing phase changes in crystals of macromolecules: status and perspectives for controlled crystal dehydration.

Florent Cipriani, Matthew W Bowler, Franck Felisaz, 2011, Journal of structural biology.

Measurement of the equilibrium relative humidity for common precipitant concentrations: facilitating controlled dehydration experiments.

S. Russi, M. Bowler, M. J. Wheeler, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural and functional comparison of fumarylacetoacetate domain containing protein 1 in human and mouse

B. Rupp, P. Jansen-Dürr, M. Bowler, 2020, Bioscience reports.

CrystalDirect-To-Beam: Opening the shortest path from crystal to data

J. Marquez, U. Zander, O. Svensson, 2019 .

Controlled dehydration, structural flexibility and gadolinium MRI contrast compound binding in the human plasma glycoprotein afamin

B. Rupp, M. Bowler, A. Naschberger, 2019, Acta crystallographica. Section D, Structural biology.

Structural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist

A. Bougdour, U. Kapp, A. Palencia, 2017, Structure.

Automation and Experience of Controlled Crystal Dehydration: Results from the European Synchrotron HC1 Collaboration

S. Brockhauser, O. Svensson, M. Weiss, 2015 .

Measurement of the intrinsic variability within protein crystals: implications for sample-evaluation and data-collection strategies.

M. Bowler, M. Bowler, 2014, Acta crystallographica. Section F, Structural biology communications.

Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF 3 - rather than by phosphoranes

N. J. Baxter, A. Hounslow, J. Waltho, 2010, Proceedings of the National Academy of Sciences.

Transition state analogue structures of human phosphoglycerate kinase establish the importance of charge balance in catalysis.

Matthew W Bowler, N. J. Baxter, A. Hounslow, 2010, Journal of the American Chemical Society.

A Spring-loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase*

Adam Round, Matthew W Bowler, Gunnar F Schröder, 2011, The Journal of Biological Chemistry.

Cyanine Conformational Restraint in the Far-Red Range.

Markus Sauer, Nikita Kumari, Valentin Magidson, 2017, Journal of the American Chemical Society.

Raoult’s law revisited: accurately predicting equilibrium relative humidity points for humidity control experiments

D. Bowler, M. Bowler, M. Bowler, 2016, Journal of applied crystallography.

Ground State Structure of F1-ATPase from Bovine Heart Mitochondria at 1.9 Å Resolution*

A. Leslie, John E. Walker, M. G. Montgomery, 2007, Journal of Biological Chemistry.

Near attack conformers dominate β-phosphoglucomutase complexes where geometry and charge distribution reflect those of substrate

C. E. Webster, N. J. Baxter, A. Hounslow, 2012, Proceedings of the National Academy of Sciences.

Structural basis for reactivating the mutant TERT promoter by cooperative binding of p52 and ETS1

Haiwei Song, V. Tergaonkar, M. Bowler, 2018, Nature Communications.

QsIA disrupts LasR dimerization in antiactivation of bacterial quorum sensing

Haiwei Song, M. Bowler, Yihu Dong, 2013, Proceedings of the National Academy of Sciences.

Computational design of amyloid self-assembling peptides bearing aromatic residues and the cell adhesive motif Arg-Gly-Asp

V. T. Forsyth, Asuka A. Orr, E. Mitchell, 2017 .

A drug repurposing screen identifies altiratinib as a selective inhibitor of a key regulatory splicing kinase and a potential therapeutic for toxoplasmosis and malaria

A. Bougdour, C. Mas, Y. Couté, 2021 .

Lsm2 and Lsm3 bridge the interaction of the Lsm1-7 complex with Pat1 for decapping activation

R. Parker, Haiwei Song, M. Bowler, 2013, Cell Research.

Recent improvements to the automatic characterization and data collection algorithms on MASSIF-1

D. Nurizzo, O. Svensson, M. Bowler, 2017, bioRxiv.

Structural Evidence for a Role of the Multi-functional Human Glycoprotein Afamin in Wnt Transport.

M. Keller, B. Rupp, D. Nurizzo, 2017, Structure.

Structural basis for the bi-functionality of human oxaloacetate decarboxylase FAHD1.

K. Scheffzek, K. Liedl, P. Jansen-Dürr, 2018, The Biochemical journal.

Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation

F. Gervasio, Ioannis Galdadas, M. Bowler, 2023, bioRxiv.

Raoult’s law revisited: accurately predicting equilibrium relative humidity points for humidity control experiments

D. Bowler, M. Bowler, M. Bowler, 2016, bioRxiv.

Two Ligand-Binding Sites on SARS-CoV-2 Non-Structural Protein 1 Revealed by Fragment-Based X-ray Screening

S. Haider, F. Kozielski, M. Bowler, 2022, bioRxiv.

Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase

A. Bougdour, C. Mas, Y. Couté, 2022, Science Translational Medicine.

Controlled dehydration, structural flexibility and gadolinium MRI contrast compound binding in the human plasma glycoprotein afamin

B. Rupp, M. Bowler, A. Naschberger, 2019, bioRxiv.

α-Fluorophosphonates reveal how a phosphomutase conserves transition state conformation over hexose recognition in its two-step reaction

N. J. Baxter, J. Waltho, M. Bowler, 2014, Proceedings of the National Academy of Sciences.

Deep mining of early antibody response in COVID-19 patients yields potent neutralisers and reveals high level of convergence

R. Cowan, J. Galson, W. Lee, 2020, bioRxiv.

Increasing the diffraction limit and internal order of a membrane protein crystal by dehydration.

D. Doyle, A. Kuo, M. Bowler, 2003, Journal of structural biology.

Structural insights into the substrate-bound condensation domains of non-ribosomal peptide synthetase AmbB

Haiwei Song, Sheena Wee, J. Gunaratne, 2022, Scientific Reports.

Why did Nature select phosphate for its dominant roles in biology

J. Waltho, M. Bowler, M. Cliff, 2010 .

Reflections on biocatalysis involving phosphorus

J. Waltho, M. Bowler, G. Blackburn, 2012, Biochemistry (Moscow).

Structural and biochemical studies of the regulation and catalytic mechanism of ATP synthase

M. Bowler, 2005 .

RoboDiff: combining a sample changer and goniometer for highly automated macromolecular crystallography experiments

Didier Nurizzo, Matthew W. Bowler, Nicolas Guichard, 2016, Acta crystallographica. Section D, Structural biology.

ISPyB for BioSAXS, the gateway to user autonomy in solution scattering experiments

Adam Round, Matthew W. Bowler, Daniel Franke, 2015, Acta crystallographica. Section D, Biological crystallography.

The Ighmbp2 helicase structure reveals the molecular basis for disease-causing mutations in DMSA1

Matthew W. Bowler, Haiwei Song, Haiwei Song, 2012, Nucleic acids research.

The Ighmbp2 helicase structure reveals the molecular basis for disease-causing mutations in DMSA1

Haiwei Song, M. Bowler, S. Lim, 2012, Nucleic acids research.

A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma

A. Bougdour, C. Mas, G. Communie, 2021, eLife.

A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental genes partitioning in Toxoplasma

A. Bougdour, C. Mas, G. Communie, 2021, bioRxiv.

How azide inhibits ATP hydrolysis by the F-ATPases.

A. Leslie, M. G. Montgomery, M. Bowler, 2006, Proceedings of the National Academy of Sciences of the United States of America.

MASSIF-1: a beamline dedicated to the fully automatic characterization and data collection from crystals of biological macromolecules

D. Nurizzo, O. Svensson, C. Mueller-Dieckmann, 2015, Journal of synchrotron radiation.

New features of the cell wall of the radio-resistant bacterium Deinococcus radiodurans.

S. McSweeney, Joanna M. Kirkpatrick, M. Bowler, 2014, Biochimica et biophysica acta.

Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses

J. Galson, W. Lee, P. Pfeffer, 2021, Frontiers in Immunology.

A novel amyloid designable scaffold and potential inhibitor inspired by GAIIG of amyloid beta and the HIV‐1 V3 loop

Joseph M Jakubowski, Asuka A. Orr, E. Mitchell, 2018, FEBS letters.

Structural basis of the PNRC2-mediated link between mrna surveillance and decapping.

R. Parker, Yoon Ki Kim, Haiwei Song, 2012, Structure.

Structural basis for Scc3-dependent cohesin recruitment to chromatin

D. Panne, C. Haering, M. Bowler, 2018, eLife.

Structural basis for blocking PD-1-mediated immune suppression by therapeutic antibody pembrolizumab

Haiwei Song, M. Bowler, S. R. Bharath, 2016, Cell Research.

MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments

Didier Nurizzo, Matthew W. Bowler, Christoph Mueller-Dieckmann, 2010, Journal of synchrotron radiation.

Identification, binding, and structural characterization of single domain anti-PD-L1 antibodies inhibitory of immune regulatory proteins PD-1 and CD80

M. Carr, F. Muskett, P. Coombs, 2022, The Journal of biological chemistry.

Conformational dynamics in phosphoglycerate kinase, an open and shut case?

M. Bowler, 2013, FEBS letters.

Fully automatic macromolecular crystallography: the impact of MASSIF-1 on the optimum acquisition and quality of data

Olof Svensson, Didier Nurizzo, Matthew W. Bowler, 2016 .

The structural mechanism of MCIA complex assembly links mitochondrial redox pathways

M. Soler‐Lopez, G. Leonard, I. Gutsche, 2023, bioRxiv.

A molecular mechanism for transthyretin amyloidogenesis

B. L. de Groot, E. Mitchell, P. Mas, 2019, Nature Communications.

Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus

S. Goff, Haiwei Song, M. Bowler, 2016, Nature Communications.

A new MR-SAD algorithm for the automatic building of protein models from low-resolution X-ray data and a poor starting model

Pavol Skubák, Demet Araç, Matthew W Bowler, 2018, IUCrJ.

Reproducible improvements in order and diffraction limit of crystals of bovine mitochondrial F(1)-ATPase by controlled dehydration.

A. Leslie, M. G. Montgomery, M. Bowler, 2006, Acta crystallographica. Section D, Biological crystallography.

Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans

S. McSweeney, M. Bowler, D. Piano, 2015, Front. Microbiol..

Charge-balanced metal fluoride complexes for protein kinase A with adenosine diphosphate and substrate peptide SP20.

N. J. Baxter, A. Hounslow, J. Waltho, 2012, Angewandte Chemie.

Fully Autonomous Characterization and Data Collection from Crystals of Biological Macromolecules.

Didier Nurizzo, Matthew W Bowler, Christoph Mueller-Dieckmann, 2019, Journal of visualized experiments : JoVE.

Interaction of human 3-phosphoglycerate kinase with its two substrates: is substrate antagonism a kinetic advantage?

C. Lionne, L. Chaloin, P. Lallemand, 2011, Journal of molecular biology.

Self-Assembled Amyloid Peptides with Arg-Gly-Asp (RGD) Motifs As Scaffolds for Tissue Engineering.

E. Mitchell, P. Tamamis, E. Mossou, 2017, ACS biomaterials science & engineering.

The Upgrade Programme for the Structural Biology beamlines at the European Synchrotron Radiation Facility – High throughput sample evaluation and automation

Didier Nurizzo, Matthew W. Bowler, Sean McSweeney, 2013 .

Structural studies of a membrane embedded chloride channel from E.Coli, a prokaryotic homologue of ClC channels

M. Bowler, 2001 .

Fully automatic characterization and data collection from crystals of biological macromolecules

Olof Svensson, Stéphanie Malbet-Monaco, Alexander Popov, 2015, Acta crystallographica. Section D, Biological crystallography.

Finding order in chaos – nanocrystals in amorphous protein gels

M. Bowler, 2021, Acta crystallographica. Section F, Structural biology communications.

A comparative anatomy of protein crystals: lessons from the automatic processing of 56 000 samples

Didier Nurizzo, Matthew W. Bowler, Olof Svensson, 2019, IUCrJ.

MXCuBE2: the dawn of MXCuBE Collaboration

Thomas Schneider, Manfred S Weiss, Olof Svensson, 2019, Journal of synchrotron radiation.

High-confidence placement of difficult-to-fit fragments into electron density by using anomalous signals - a case study using hits targeting SARS-CoV-2 non-structural protein 1

F. Kozielski, M. Bowler, V. Mykhaylyk, 2023, bioRxiv.

The status of the macromolecular crystallography beamlines at the European Synchrotron Radiation Facility

Adam Round, Didier Nurizzo, Matthew W. Bowler, 2015 .

Automatic processing of macromolecular crystallography X-ray diffraction data at the ESRF

Olof Svensson, Matthew W. Bowler, Gordon Leonard, 2013, Journal of applied crystallography.

Assessing the Influence of Mutation on GTPase Transition States by Using X‐ray Crystallography, 19F NMR, and DFT Approaches

N. Richards, J. Waltho, M. Bowler, 2017, Angewandte Chemie.

Observing enzyme ternary transition state analogue complexes by 19F NMR spectroscopy† †Electronic supplementary information (ESI) available: Supporting Figures, HQSC NMR spectra, LC-MS/MS data and X-ray diffraction refinement data are described. See DOI: 10.1039/c7sc04204c

M. Bowler, Jill von Velsen, D. Jakeman, 2017, Chemical science.

Recent progress in robot-based systems for crystallography and their contribution to drug discovery

Didier Nurizzo, Matthew W Bowler, Jean-Luc Ferrer, 2013, Expert opinion on drug discovery.

Diffraction cartography: applying microbeams to macromolecular crystallography sample evaluation and data collection.

Sebastien Petitdemange, Olof Svensson, Matthew W Bowler, 2010, Acta crystallographica. Section D, Biological crystallography.

The sweet quartet: Binding of fucose to the norovirus capsid.

Matthew W Bowler, Anna D Koromyslova, M. Bowler, 2015, Virology.

A comparative anatomy of protein crystals: lessons from the automatic processing of 56 000 samples

Olof Svensson, Didier Nurizzo, Maciej Gilski, 2019, bioRxiv.

Assessing the Influence of Mutation on GTPase Transition States by Using X‐ray Crystallography, 19F NMR, and DFT Approaches

N. Richards, J. Waltho, M. Bowler, 2017, Angewandte Chemie.

van der Waals Contact between Nucleophile and Transferring Phosphorus Is Insufficient To Achieve Enzyme Transition-State Architecture

L. A. Johnson, C. R. Trevitt, N. J. Baxter, 2018, ACS Catalysis.

Transition state analogue structures of human phosphoglycerate kinase establish the importance of charge balance in catalysis.

N. J. Baxter, A. Hounslow, J. Waltho, 2010, Journal of the American Chemical Society.

MgF(3)(-) and alpha-galactose 1-phosphate in the active site of beta-phosphoglucomutase form a transition state analogue of phosphoryl transfer.

N. J. Baxter, A. Hounslow, J. Waltho, 2009, Journal of the American Chemical Society.

Direct cryocooling of naked crystals: are cryoprotection agents always necessary?

M. Bowler, E. Pellegrini, D. Piano, 2011, Acta crystallographica. Section D, Biological crystallography.

The use of workflows in the design and implementation of complex experiments in macromolecular crystallography

Olof Svensson, Alexander Popov, Matthew W. Bowler, 2012, Acta crystallographica. Section D, Biological crystallography.

Multi-position data collection and dynamic beam sizing: recent improvements to the automatic data-collection algorithms on MASSIF-1

Olof Svensson, Didier Nurizzo, Matthew W Bowler, 2018, Acta crystallographica. Section D, Structural biology.

Crystal Structures of Lsm3, Lsm4 and Lsm5/6/7 from Schizosaccharomyces pombe

Haiwei Song, M. Bowler, Donghui Wu, 2012, PloS one.

MASSIF-1 : a beamline dedicated to the fully automatic characterization and data collection from crystals of biological macromolecules

D. Nurizzo, O. Svensson, A. Beteva, 2015 .