B. Gopal

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Crystallization and preliminary X-ray diffraction studies of Staphylococcus aureus homoserine dehydrogenase.

V. Navratna, B. Gopal, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

The crystal structure of NusB from Mycobacterium tuberculosis

S. Smerdon, J. Brannigan, L. Haire, 2000, Nature Structural Biology.

Crystal structure of the transcription elongation/anti-termination factor NusA from Mycobacterium tuberculosis at 1.7 A resolution.

A. Lane, S. Gamblin, E. Dodson, 2001, Journal of molecular biology.

Structure-Based Phylogeny as a Diagnostic for Functional Characterization of Proteins with a Cupin Fold

Narayanaswamy Srinivasan, Balasubramanian Gopal, N. Srinivasan, 2009, PloS one.

Crystallization and preliminary X-ray diffraction studies on the N-utilizing substance-B (NusB) from Mycobacterium tuberculosis.

S. Smerdon, L. Haire, B. Gopal, 2000, Acta crystallographica. Section D, Biological crystallography.

The mechanism of upstream activation in the rrnB operon of Mycobacterium smegmatis is different from the Escherichia coli paradigm.

B. Gopal, R. Cox, K. Papavinasasundaram, 2005, Microbiology.

The fused SnoaL_2 domain in the Mycobacterium tuberculosis sigma factor σJ modulates promoter recognition

A. Gupta, B. Gopal, K. Goutam, 2017, Nucleic acids research.

AZOLLA PRIMAEVA AND ITS PHYLOGENETIC SIGNIFICANCE

B. Gopal, L. Hills, 1967 .

Inter-domain interactions influence the stability and catalytic activity of the bi-domain protein tyrosine phosphatase PTP99A.

B. Gopal, K. Goutam, L. Madan, 2012, Biochimica et biophysica acta.

Design, Synthesis, and Experimental Validation of Peptide Ligands Targeting Mycobacterium tuberculosis σ Factors.

N. Srinivasan, Sneha Vishwanath, J. Chatterjee, 2017, Biochemistry.

Redox Regulation of the Quorum-sensing Transcription Factor AgrA by Coenzyme A

I. Gout, V. Filonenko, S. Wigneshweraraj, 2021, Antioxidants.

Evaluation of specificity determinants in Mycobacterium tuberculosis σ/anti-σ factor interactions.

B. Gopal, Ashish Runthala, A. Jamithireddy, 2019, Biochemical and biophysical research communications.

Structural insights into the catalytic mechanism of Bacillus subtilis BacF.

B. Gopal, A. Deshmukh, 2020, Acta crystallographica. Section F, Structural biology communications.

The crystal structure of a quercetin 2,3-dioxygenase from Bacillus subtilis suggests modulation of enzyme activity by a change in the metal ion at the active site(s).

S. Betz, A. Kossiakoff, B. Gopal, 2005, Biochemistry.

Refolding and simultaneous purification by three‐phase partitioning of recombinant proteins from inclusion bodies

R. Varadarajan, M. N. Gupta, Kanika Bajaj, 2008, Protein science : a publication of the Protein Society.

Cavity Waters Govern Insulin Association and Release: Inferences from Experimental Data and Molecular Dynamics Simulations

B. Bagchi, Saumyak Mukherjee, Sayantan Mondal, 2017, 1710.08443.

Structural basis for the catalytic mechanism of homoserine dehydrogenase.

G. Reddy, V. Navratna, B. Gopal, 2015, Acta crystallographica. Section D, Biological crystallography.

Particle Uptake Driven Phagocytosis in Macrophages and Neutrophils Enhances Bacterial Clearance

Sveta Chakrabarti, S. Jhunjhunwala, B. Gopal, 2021, bioRxiv.

Mycobacterium tuberculosis Transcription Factor EmbR Regulates the Expression of Key Virulence Factors That Aid in Ex Vivo and In Vivo Survival

Suresh Kumar, V. Nandicoori, B. Gopal, 2022, mBio.

Structure of an amidohydrolase, SACOL0085, from methicillin-resistant Staphylococcus aureus COL.

B. Gopal, S. Misquith, Melwin Colaço, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Identification of a new and diverse set of Mycobacterium tuberculosstais uracil-DNA glycosylase (MtUng) inhibitors using structure-based virtual screening: experimental validation and molecular dynamics studies.

B. Gopal, U. Varshney, S. Sundriyal, 2022, Bioorganic & medicinal chemistry letters.

Use of a molecular beacon based fluorescent method for assaying uracil DNA glycosylase (Ung) activity and inhibitor screening

B. Gopal, U. Varshney, S. Sundriyal, 2021, Biochemistry and biophysics reports.

Crystallization and preliminary X-ray diffraction studies on the bicupin YwfC from Bacillus subtilis.

B. Gopal, M. Rajavel, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Tackling both the player and the ball: lessons from crystallographic studies on the N-utilization substance B (NusB) from Mycobacterium tuberculosis

L. Haire, B. Gopal, 2001 .

Variability of calcium binding to EF-hand motifs probed by electrospray ionization mass spectrometry

A. Surolia, B. Gopal, M. Murthy, 2001, Journal of the American Society for Mass Spectrometry.

Correlation between the Sucrose Synthase Protein Subfamilies, Variations in Structure and Expression in Stress-derived Expressed Sequence Tag Datasets

Anil Kumar, B. Gopal, B. Jayashree, 2008 .

Curation and cheminformatics analysis of a Ugi-reaction derived library (URDL) of synthetically tractable small molecules for virtual screening application.

B. Gopal, S. Sundriyal, Nancy Tripathi, 2022, Molecular diversity.

Molecular Basis for the Role of Staphylococcus aureus Penicillin Binding Protein 4 in Antimicrobial Resistance

Varun Sood, V. Navratna, B. Gopal, 2009, Journal of bacteriology.

Thermodynamics of target peptide recognition by calmodulin and a calmodulin analogue: implications for the role of the central linker

M. Murthy, A. Surolia, A. Bhattacharya, 1999, FEBS letters.

Induction of a spectroscopically defined transition by guanidinium hydrochloride on a recombinant calcium binding protein from Entamoeba histolytica

A. Surolia, A. Bhattacharya, B. Gopal, 1998, FEBS letters.

Crystallization and preliminary X-ray studies of a recombinant calcium-binding protein from Entamoeba histolytica.

A. Bhattacharya, B. Gopal, S. Bhattacharya, 1998, Acta Crystallographica Section D: Biological Crystallography.

Thermodynamics of metal ion binding and denaturation of a calcium binding protein from Entamoeba histolytica.

A. Surolia, A. Bhattacharya, B. Gopal, 1997, Biochemistry.

The unique N-terminal region of Mycobacterium tuberculosis sigma factor A plays a dominant role in the essential function of this protein

Divya Tej Sowpati, V. Nandicoori, D. T. Sowpati, 2023, The Journal of biological chemistry.

Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues

S. Ramachandran, V. Navratna, B. Gopal, 2016, Scientific Reports.

Structure and nucleotide specificity of Staphylococcus aureus dihydrodipicolinate reductase (DapB)

V. Navratna, B. Gopal, T. Girish, 2011, FEBS letters.

The Topology of the l-Arginine Exporter ArgO Conforms to an Nin-Cout Configuration in Escherichia coli: Requirement for the Cytoplasmic N-Terminal Domain, Functional Helical Interactions, and an Aspartate Pair for ArgO Function

A. Gupta, S. Dubey, B. Gopal, 2016, Journal of bacteriology.

Over-expression and purification strategies for recombinant multi-protein oligomers: a case study of Mycobacterium tuberculosis σ/anti-σ factor protein complexes.

B. Gopal, K. Thakur, T. Praveena, 2010, Protein expression and purification.

Conformational basis for substrate recruitment in protein tyrosine phosphatase 10D.

B. Gopal, L. Madan, 2011, Biochemistry.

Crystal Structure of Staphylococcus aureus Metallopeptidase (Sapep) Reveals Large Domain Motions between the Manganese-bound and Apo-states*

B. Gopal, T. Girish, 2010, The Journal of Biological Chemistry.

Structural and Biochemical Bases for the Redox Sensitivity of Mycobacterium tuberculosis RslA

B. Gopal, K. Thakur, T. Praveena, 2010, Journal of molecular biology.

Structural biology of Mycobacterium tuberculosis proteins: the Indian efforts.

N. Chandra, M. Vijayan, K. Sekar, 2011, Tuberculosis.

What Gives an Insulin Hexamer Its Unique Shape and Stability? Role of Ten Confined Water Molecules.

B. Bagchi, Saumyak Mukherjee, Sayantan Mondal, 2018, The journal of physical chemistry. B.

Role of Bacillus subtilis BacB in the Synthesis of Bacilysin

A. Mitra, B. Gopal, M. Rajavel, 2009, The Journal of Biological Chemistry.

Selectivity among Anti-σ Factors by Mycobacterium tuberculosis ClpX Influences Intracellular Levels of Extracytoplasmic Function σ Factors

V. Nandicoori, B. Gopal, Prabhjot Kaur, 2018, bioRxiv.

The crystal structure of Mycobacterium tuberculosis high-temperature requirement A protein reveals an autoregulatory mechanism.

A. Gupta, B. Gopal, D. Behera, 2018, Acta crystallographica. Section F, Structural biology communications.

Novel insights into ATP-stimulated cleavage of branched DNA and RNA substrates through structure-guided studies of the Holliday junction resolvase RuvX.

B. Gopal, K. Muniyappa, Manoj Thakur, 2021, Journal of molecular biology.

Bi-domain protein tyrosine phosphatases reveal an evolutionary adaptation to optimize signal transduction.

Lalima G. Ahuja, B. Gopal, 2014, Antioxidants & redox signaling.

Metallopeptidase (Sapep) Staphylococcus Aureus

B. Gopal, T. Girish, 2012 .

Structural and functional characterization of Staphylococcus aureus dihydrodipicolinate synthase

B. Gopal, E. Sharma, T. Girish, 2008, FEBS letters.

Modulation of Catalytic Activity in Multi-Domain Protein Tyrosine Phosphatases

R. Sowdhamini, K. Shameer, B. Gopal, 2011, PloS one.

Effect of amino acid substitutions at the subunit interface on the stability and aggregation properties of a dimeric protein: Role of Arg 178 and Arg 218 at the dimer interface of thymidylate synthase

D. Santi, P. Balaram, B. Gopal, 1999, Proteins.

Mycobacterium tuberculosis Rv2704 is a member of the YjgF/YER057c/UK114 family

B. Gopal, K. Thakur, T. Praveena, 2010, Proteins.

Draft Genome Sequence of the Community-Associated Staphylococcus aureus Sequence Type 88 Strain LVP-7, Isolated from an Ocular Infection

H. Subramanya, S. Vembar, B. Gopal, 2021, Microbiology Resource Announcements.

Draft Genome Sequence of the Community-Associated Staphylococcus aureus Sequence Type 88 Strain LVP-7, Isolated from an Ocular Infection

H. Subramanya, B. Gopal, S. Nadig, 2021 .

Disulfide engineering at the dimer interface of lactobacillus casei thymidylate synthase: Crystal structure of the T155C/E188C/C244T mutant

S. Parthasarathy, D. Santi, S. Ray, 2008, Protein science : a publication of the Protein Society.

X‐ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate

S. Sarma, B. Gopal, K. Thakur, 2010, The FEBS journal.

Probing the influence of non-covalent contact networks identified by charge density analysis on the oxidoreductase BacC

T. N. Guru Row, H. Balaram, B. Gopal, 2017, Protein engineering, design & selection : PEDS.

Structural and biochemical characteristics of two Staphylococcus epidermidis RNase J paralogs RNase J1 and RNase J2

B. Gopal, S. Nadig, R. Raj, 2020, The Journal of Biological Chemistry.

Mycobacterium tuberculosis SufR Responds to Nitric oxide via its 4Fe-4S cluster and Regulates Fe-S cluster Biogenesis for Persistence in Mice

V. Nagaraja, Amit Singh, A. Seshasayee, 2020 .

Role of a PAS sensor domain in the Mycobacterium tuberculosis transcription regulator Rv1364c.

B. Gopal, R. Jaiswal, G. Manjeera, 2010, Biochemical and biophysical research communications.

A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains

F. Vandenesch, A. Norrby-Teglund, M. Svensson, 2016, Scientific Reports.

Spectroscopic and thermodynamic characterization of the transcription antitermination factor NusE and its interaction with NusB from Mycobacterium tuberculosis.

A. Lane, B. Gopal, M. Colston, 2001, Biochemistry.

Crystallization and preliminary X-ray diffraction studies of two domains of a bilobed extra-cytoplasmic function sigma factor SigC from Mycobacterium tuberculosis.

B. Gopal, K. Thakur, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Analysis of Conformational Variation in Macromolecular Structural Models

Babu A. Manjasetty, Balasubramanian Gopal, B. Manjasetty, 2012, PloS one.

Structural and Biophysical Studies on Two Promoter Recognition Domains of the Extra-cytoplasmic Function σ Factor σC from Mycobacterium tuberculosis*

Balasubramanian Gopal, B. Gopal, K. Thakur, 2007, Journal of Biological Chemistry.

Structural and biophysical studies on two promoter recognition domains of the extra-cytoplasmic function sigma factor sigma(C) from Mycobacterium tuberculosis.

B. Gopal, K. Thakur, B Gopal, 2007, The Journal of biological chemistry.

Mycobacterium tuberculosis RsdA provides a conformational rationale for selective regulation of σ-factor activity by proteolysis

B. Gopal, R. Jaiswal, G. Manjeera, 2013, Nucleic acids research.

Influence of the AgrC-AgrA Complex on the Response Time of Staphylococcus aureus Quorum Sensing

Aneesa Fasim, B. Gopal, G. Arakere, 2014, Journal of bacteriology.

Nitric oxide-inducible Fe-S cluster biogenesis enables Mycobacterium tuberculosis to persist in mice

V. Nagaraja, Amit Singh, R. Jha, 2020, bioRxiv.

The crystal structure of NusB from Mycobacterium tuberculosis.

S. Smerdon, J. Brannigan, L. Haire, 2000 .

A high-affinity interaction between NusA and the rrn nut site in Mycobacterium tuberculosis.

B. Gopal, M. Colston, S. Pennell, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Destabilization of Insulin Hexamer in Water-Ethanol Binary Mixture.

B. Bagchi, Saumyak Mukherjee, Sayantan Mondal, 2019, The journal of physical chemistry. B.

Titania nanotube-modified screen printed carbon electrodes enhance the sensitivity in the electrochemical detection of proteins.

A. J. Bhattacharyya, V. Navratna, B. Gopal, 2014, Bioelectrochemistry.

Determination of Redox Sensitivity in Structurally Similar Biological Redox Sensors.

A. J. Bhattacharyya, B. Gopal, A. Jamithireddy, 2017, The journal of physical chemistry. B.

The crystal structure of the catalytic domain of the chick retinal neurite inhibitor—receptor protein tyrosine phosphatase CRYP‐2/cPTPRO

B. Gopal, T. Girish, 2007, Proteins: Structure, Function, and Bioinformatics.

Crystallization and preliminary X-ray diffraction studies on the catalytic domain of the chick retinal neurite-inhibitory factor CRYP-2.

B. Gopal, T. Girish, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural basis for the redox sensitivity of the Mycobacterium tuberculosis SigK-RskA σ-anti-σ complex.

B. Gopal, Radhika Gupta, R. Gokhale, 2014, Acta crystallographica. Section D, Biological crystallography.

Conformational basis for substrate recognition and regulation of catalytic activity in Staphylococcus aureus nucleoside di-phosphate kinase.

B. Gopal, S. Srivastava, K. Rajasree, 2011, Biochimica et biophysica acta.

Allosteric Determinants in High Temperature Requirement A Enzymes Are Conserved and Regulate the Population of Active Conformations.

A. Gupta, G. Reddy, B. Gopal, 2023, ACS chemical biology.

Fruit Development and Structure in Some Indian Bamboos

B. Gopal, H. Ram, 1987 .

Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment.

B. Gopal, U. Varshney, S. Sundriyal, 2023, European journal of medicinal chemistry.

Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution

E. Woo, B. Gopal, U. Varshney, 2023, Nucleic acids research.

PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactomes

Khader Shameer, Ramanathan Sowdhamini, Lalima L. Madan, 2010, BMC Bioinformatics.

Old fold in a new X‐ray diffraction dataset? Low‐resolution molecular replacement using representative structural templates can provide phase information

B. Gopal, M. Rajavel, Thulasi Warrier, 2006, Proteins.

Characterization of Staphylococcus epidermidis Polynucleotide phosphorylase and its interactions with ribonucleases RNase J1 and RNase J2.

B. Gopal, R. Raj, Sharmistha Mitra, 2018, Biochemical and biophysical research communications.

Inter-domain interactions influence the stability and catalytic activity of the bi-domain protein tyrosine phosphatase PTP99A.

B. Gopal, K. Goutam, L. Madan, 2012, Biochimica et biophysica acta.

Addition of a polypeptide stretch at the N-terminus improves the expression, stability and solubility of recombinant protein tyrosine phosphatases from Drosophila melanogaster.

B. Gopal, L. Madan, 2008, Protein expression and purification.

Crystallographic studies of the extracytoplasmic function σ factor σ(J) from Mycobacterium tuberculosis.

A. Gupta, B. Gopal, K. Goutam, 2015, Acta crystallographica. Section F, Structural biology communications.

Conformational features of the Staphylococcus aureus AgrA-promoter interactions rationalize quorum-sensing triggered gene expression

Aneesa Fasim, B. Gopal, K. Rajasree, 2016, Biochemistry and biophysics reports.