P. Řezáčová

发表

Molecular analysis of the HIV-1 resistance development: enzymatic activities, crystal structures, and thermodynamics of nelfinavir-resistant HIV protease mutants.

Lubomír Rulísek, Jana Pokorná, Jenelle Bray, 2007, Journal of molecular biology.

Mutations in HIV-1 gag and pol Compensate for the Loss of Viral Fitness Caused by a Highly Mutated Protease

J. Konvalinka, V. Müller, H. Kräusslich, 2012, Antimicrobial Agents and Chemotherapy.

Thermodynamic and structural analysis of HIV protease resistance to darunavir – analysis of heavily mutated patient‐derived HIV‐1 proteases

J. Konvalinka, J. Brynda, M. Kožíšek, 2014, The FEBS journal.

Differences in crystallization of two LinB variants from Sphingobium japonicum UT26.

J. Damborský, R. Chaloupkova, M. Kutý, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallographic analysis of new psychrophilic haloalkane dehalogenases: DpcA from Psychrobacter cryohalolentis K5 and DmxA from Marinobacter sp. ELB17.

J. Damborský, R. Chaloupkova, M. Kutý, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structure-aided design of novel inhibitors of HIV protease based on a benzodiazepine scaffold.

J. Konvalinka, J. Brynda, I. Císařová, 2012, Journal of medicinal chemistry.

Regular arrangement of periodates bound to lysozyme.

J. Fiala, M. Weiss, J. Brynda, 2005, Acta crystallographica. Section D, Biological crystallography.

QM/MM calculations reveal the different nature of the interaction of two carborane-based sulfamide inhibitors of human carbonic anhydrase II.

P. Mader, J. Brynda, P. Hobza, 2013, The journal of physical chemistry. B.

Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus.

J. Konvalinka, J. Pokorná, M. Kožíšek, 2018 .

Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus

J. Konvalinka, J. Pokorná, M. Kožíšek, 2018, Viruses.

A novel structurally characterized haloacid dehalogenase superfamily phosphatase from Thermococcus thioreducens with diverse substrate specificity.

M. Pusey, J. Brynda, J. Mesters, 2019, Acta crystallographica. Section D, Structural biology.

Atomic resolution crystal structure of Sapp2p, a secreted aspartic protease from Candida parapsilosis.

I. Pichová, J. Brynda, L. Marečková, 2015, Acta crystallographica. Section D, Biological crystallography.

Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation

V. Veverka, M. Hubálek, K. Cermakova, 2018, Proceedings of the National Academy of Sciences.

Structural and functional analysis of a novel haloalkane dehalogenase with two halide-binding sites.

Yukari Sato, J. Damborský, R. Chaloupkova, 2014, Acta crystallographica. Section D, Biological crystallography.

Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch.

J. Vondrášek, J. McKerrow, J. Brynda, 2014, Structure.

Structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor.

J. Konvalinka, J. Hodek, M. Kožíšek, 2020, Antiviral research.

Ranking Power of the SQM/COSMO Scoring Function on Carbonic Anhydrase II-Inhibitor Complexes.

Ramachandran Gnanasekaran, J. Brynda, V. Veverka, 2018 .

The crystal structure of the effector‐binding domain of the trehalose repressor TreR from Bacillus subtilis 168 reveals a unique quarternary assembly

A. Joachimiak, Z. Otwinowski, D. Borek, 2007, Proteins.

Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery

H. Madhani, C. Craik, J. Konvalinka, 2021, Journal of medicinal chemistry.

3,5,7-Substituted Pyrazolo[4,3-d]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders.

M. Strnad, L. Havlícek, V. Kryštof, 2022, Journal of medicinal chemistry.

Inhibitors of CA IX Enzyme Based on Polyhedral Boron Compounds

V. Král, J. Brynda, M. Hajdúch, 2021, Chembiochem : a European journal of chemical biology.

Carborane-based carbonic anhydrase inhibitors.

P. Mader, J. Brynda, P. Cígler, 2013, Angewandte Chemie.

Crystal structure of native β‐N‐acetylhexosaminidase isolated from Aspergillus oryzae sheds light onto its substrate specificity, high stability, and regulation by propeptide

Z. Otwinowski, J. Brynda, P. Man, 2018, The FEBS journal.

Structural and catalytic effects of surface loop-helix transplantation within haloalkane dehalogenase family

Yukari Sato, J. Damborský, R. Chaloupkova, 2020, Computational and structural biotechnology journal.

Crystallization of the Effector-Binding Domain of Repressor DeoR from Bacillus subtilis

K. Procházková, P. Řezáčová, M. Fábry, 2013 .

Crystal structure of the cold-adapted haloalkane dehalogenase DpcA from Psychrobacter cryohalolentis K5.

J. Damborský, R. Chaloupkova, J. Brynda, 2019, Acta crystallographica. Section F, Structural biology communications.

Crystal structure of native α-L-rhamnosidase from Aspergillus terreus.

Z. Otwinowski, P. Mader, V. Křen, 2018, Acta crystallographica. Section D, Structural biology.

Inhibitor binding at the protein interface in crystals of a HIV-1 protease complex.

J. Konvalinka, J. Brynda, P. Řezáčová, 2004, Acta crystallographica. Section D, Biological crystallography.

Recombinant fragment of an antibody tailored for direct radioiodination

V. Král, R. Mikołajczak, P. Řezáčová, 2012 .

The structure and function of Iristatin, a novel immunosuppressive tick salivary cystatin

J. Kopecký, E. Schmitt, P. Řezáčová, 2019, Cellular and Molecular Life Sciences.

Crystallization and preliminary crystallographic characterization of the iron-regulated outer membrane lipoprotein FrpD from Neisseria meningitidis.

D. Kavan, M. Kutý, P. Šebo, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists

Vojtěch Havlíček, Michal Hocek, J. Brynda, 2022, Journal of medicinal chemistry.

Crystallization and diffraction analysis of thioredoxin reductase from Streptomyces coelicolor.

J. Brynda, P. Řezáčová, M. Kollarova, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and diffraction analysis of the serpin IRS-2 from the hard tick Ixodes ricinus.

J. Brynda, P. Řezáčová, J. Chmelař, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

The structure and function of Iristatin, a novel immunosuppressive tick salivary cystatin

J. Kopecký, E. Schmitt, P. Řezáčová, 2019, Cellular and Molecular Life Sciences.

3H-Pyrazolo[4,3-f]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo.

V. Kryštof, P. Řezáčová, M. Lepšík, 2021, Journal of Medicinal Chemistry.

Conformationally constrained nucleoside phosphonic acids--potent inhibitors of human mitochondrial and cytosolic 5'(3')-nucleotidases.

J. Brynda, V. Veverka, P. Řezáčová, 2014, Organic & biomolecular chemistry.

Molecular mechanism for the action of the anti-CD44 monoclonal antibody MEM-85.

V. Král, D. Svergun, Zdeněk Tošner, 2015, Journal of structural biology.

Design of HIV protease inhibitors based on inorganic polyhedral metallacarboranes.

J. Konvalinka, H. Kräusslich, J. Brynda, 2009, Journal of medicinal chemistry.

From nonpeptide toward noncarbon protease inhibitors: Metallacarboranes as specific and potent inhibitors of HIV protease

J. Konvalinka, Z. Otwinowski, H. Kräusslich, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Medicinal Application of Carboranes: Inhibition of HIV Protease

J. Konvalinka, Pavel Matějíček, P. Cígler, 2011 .

Inorganic polyhedral metallacarborane inhibitors of HIV protease: a new approach to overcoming antiviral resistance.

J. Konvalinka, J. Brynda, V. Král, 2008, Journal of medicinal chemistry.

Cobalt Bis(dicarbollide) Alkylsulfonamides: Potent and Highly Selective Inhibitors of Tumor Specific Carbonic Anhydrase IX.

V. Král, J. Brynda, P. Řezáčová, 2020, ChemPlusChem.

In situ proteolysis of an N-terminal His tag with thrombin improves the diffraction quality of human aldo-keto reductase 1C3 crystals.

J. Brynda, Z. Voburka, E. Petri, 2018, Acta crystallographica. Section F, Structural biology communications.

Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX.

M. Havranek, V. Král, J. Brynda, 2020, European journal of medicinal chemistry.

Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni*

Jindrich Fanfrlík, Jana Váchová, J. McKerrow, 2011, The Journal of Biological Chemistry.

Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(Het)aryl-7-deazaadenine ribonucleosides.

Helena Zábranská, I. Pichová, R. Pohl, 2014, Journal of medicinal chemistry.

A phenylnorstatine inhibitor binding to HIV-1 protease: geometry, protonation, and subsite-pocket interactions analyzed at atomic resolution.

Milan Soucek, J. Konvalinka, J. Brynda, 2004, Journal of medicinal chemistry.

Direct Introduction of an Alkylsulfonamido Group on C-sites of Isomeric Carboranes; the Influence of Stereochemistry on Inhibitory Activity Against Cancer-associated Carbonic Anhydrase IX Isoenzyme.

J. Brynda, P. Řezáčová, J. Holub, 2020, Chemistry.

Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms.

C. Supuran, J. Brynda, S. Ferro, 2015, European journal of medicinal chemistry.

Synthesis, structure-activity relationship studies, and X-ray crystallographic analysis of arylsulfonamides as potent carbonic anhydrase inhibitors.

C. Supuran, P. Mader, D. Vullo, 2012, Journal of medicinal chemistry.

DNA-linked inhibitor antibody assay (DIANA) as a new method for screening influenza neuraminidase inhibitors.

J. Konvalinka, I. Císařová, M. Kožíšek, 2018 .

DNA-linked inhibitor antibody assay (DIANA) as a new method for screening influenza neuraminidase inhibitors

J. Konvalinka, I. Císařová, M. Kožíšek, 2018, The Biochemical journal.

Investigation of flexibility of neuraminidase 150-loop using tamiflu derivatives in influenza A viruses H1N1 and H5N1.

J. Konvalinka, M. Kožíšek, P. Řezáčová, 2019, Bioorganic & medicinal chemistry.

Kinetic, thermodynamic and structural analysis of tamiphosphor binding to neuraminidase of H1N1 (2009) pandemic influenza.

J. Konvalinka, M. Kožíšek, P. Řezáčová, 2016, European journal of medicinal chemistry.

Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure.

V. Kryštof, P. Řezáčová, J. Jansa, 2021, European journal of medicinal chemistry.

The crystal structure of the secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A.

I. Pichová, J. Brynda, P. Řezáčová, 2009, Journal of structural biology.

3,5,7-Substituted Pyrazolo[4,3- d]pyrimidine Inhibitors of Cyclin-Dependent Kinases and Their Evaluation in Lymphoma Models.

M. Strnad, L. Havlícek, V. Kryštof, 2019, Journal of medicinal chemistry.

Crystal structure of a cross-reaction complex between an anti-HIV-1 protease antibody and an HIV-2 protease peptide.

J. Lescar, J. Brynda, P. Řezáčová, 2005, Journal of structural biology.

Structural basis for the interaction between carbonic anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides.

C. Supuran, P. Mader, J. Brynda, 2011, Journal of medicinal chemistry.

A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation.

P. Kopacek, J. Ribeiro, J. Kopecký, 2011, Blood.

An evolutionary molecular adaptation of an unusual stefin from the liver fluke Fasciola hepatica redefines the cystatin superfamily

P. Řezáčová, Pavla Bartošová-Sojková, M. Horn, 2023, The Journal of biological chemistry.

The crystal structure of protease Sapp1p from Candida parapsilosis in complex with the HIV protease inhibitor ritonavir

I. Pichová, J. Brynda, P. Řezáčová, 2012, Journal of enzyme inhibition and medicinal chemistry.

Structural insights into tick-borne encephalitis virus neutralization and animal protection by a therapeutic antibody

G. Chojnowski, V. Lamzin, P. Řezáčová, 2021, bioRxiv.

Stabilization of antibody structure upon association to a human carbonic anhydrase IX epitope studied by X‐ray crystallography, microcalorimetry, and molecular dynamics simulations

V. Král, P. Mader, J. Brynda, 2007, Proteins.

Characterization of new highly selective pyrazolo[4,3-d]pyrimidine inhibitor of CDK7

L. Havlícek, V. Kryštof, P. Řezáčová, 2023, bioRxiv.

Validation and structural characterization of the LEDGF/p75-MLL interface as a new target for the treatment of MLL-dependent leukemia.

J. Schwaller, V. Veverka, K. Cermakova, 2014, Cancer research.

Crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata.

J. Andersen, J. Kopecký, G. Paesen, 2010, The Biochemical journal.

Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors

A. Renslo, J. Brynda, C. Caffrey, 2020, ACS infectious diseases.

Link between a novel human gammaD-crystallin allele and a unique cataract phenotype explained by protein crystallography.

J. Brynda, S. Kmoch, P. Řezáčová, 2000, Human molecular genetics.

Engineering a de Novo Transport Tunnel

Jan Brezovsky, Zbynek Prokop, Artur Gora, 2016 .

Structural basis of HIV-1 and HIV-2 protease inhibition by a monoclonal antibody.

J. Lescar, J. Brynda, P. Řezáčová, 2001, Structure.

Inhibition of the HIV‐1 and HIV‐2 proteases by a monoclonal antibody

J. Lescar, J. Brynda, P. Řezáčová, 1999, Protein science : a publication of the Protein Society.

Crystal structure and putative function of small Toprim domain‐containing protein from Bacillus stearothermophilus

Zbyszek Otwinowski, Dominika Borek, Andrzej Joachimiak, 2007, Proteins.

Oligomeric interface modulation causes misregulation of purine 5´-nucleotidase in relapsed leukemia

V. Veverka, P. Man, P. Řezáčová, 2016, BMC Biology.

N-Glycosylation can selectively block or foster different receptor–ligand binding modes

I. Vattulainen, V. Veverka, P. Řezáčová, 2021, Scientific Reports.

N-glycosylation blocks and simultaneously fosters different receptor-ligand binding sites: the chameleonic CD44–hyaluronan interaction

I. Vattulainen, V. Veverka, P. Řezáčová, 2020, bioRxiv.

Current and Novel Inhibitors of HIV Protease

J. Konvalinka, P. Řezáčová, L. Machala, 2009, Viruses.

Ninety-Nine Is Not Enough: Molecular Characterization of Inhibitor-Resistant Human Immunodeficiency Virus Type 1 Protease Mutants with Insertions in the Flap Region

Monique Nijhuis, Ron M. Kagan, Charles A. Boucher, 2008, Journal of Virology.

Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif

V. Veverka, K. Cermakova, K. Procházková, 2015, Nature Communications.

Metallacarborane sulfamides: unconventional, specific, and highly selective inhibitors of carbonic anhydrase IX.

V. Král, J. Brynda, P. Džubák, 2019, Journal of medicinal chemistry.

Capturing a dynamically interacting inhibitor by paramagnetic NMR spectroscopy.

J. Konvalinka, J. Brynda, V. Veverka, 2019, Physical chemistry chemical physics : PCCP.

Rutinosidase from Aspergillus niger: Crystal structure and insight into the enzymatic activity.

V. Křen, J. Brynda, L. Biedermannová, 2020, The FEBS journal.

Triggering HIV polyprotein processing by light using rapid photodegradation of a tight-binding protease inhibitor

J. Konvalinka, H. Kräusslich, B. Müller, 2015, Nature Communications.

Crystal structures of the effector‐binding domain of repressor Central glycolytic gene Regulator from Bacillus subtilis reveal ligand‐induced structural changes upon binding of several glycolytic intermediates

Zbyszek Otwinowski, Andrzej Joachimiak, A. Joachimiak, 2008, Molecular microbiology.

Backbone resonance assignments of the outer membrane lipoprotein FrpD from Neisseria meningitidis

V. Veverka, L. Bumba, P. Řezáčová, 2014, Biomolecular NMR assignments.

Azanitrile Inhibitors of the SmCB1 Protease Target Are Lethal to Schistosoma mansoni: Structural and Mechanistic Insights into Chemotype Reactivity

M. Gütschow, C. Caffrey, P. Řezáčová, 2020, ACS infectious diseases.

Kinetic and structural characterization of an alternatively spliced variant of human mitochondrial 5′(3′)-deoxyribonucleotidase

J. Brynda, V. Veverka, P. Řezáčová, 2015, Journal of Enzyme Inhibition and Medicinal Chemistry.

Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel.

Jan Brezovsky, Zbynek Prokop, Eva Sebestova, 2013, Angewandte Chemie.

Highly Mutated Protease for the Loss of Viral Fitness Caused by a Compensate pol and gag Mutations in HIV-1

J. Konvalinka, V. Müller, H. Kräusslich, 2012 .

Structure-Based Optimization of Bisphosphonate Nucleoside Inhibitors of Human 5′(3′)-deoxyribonucleotidases

J. Brynda, P. Řezáčová, M. Buděšínský, 2018, European Journal of Organic Chemistry.

Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.

V. Veverka, J. Trka, D. Ascher, 2018 .

Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation

David B. Ascher, Petr Novák, William L. Carroll, 2018, Leukemia.

Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors

I. Pichová, J. Brynda, P. Řezáčová, 2023, Journal of medicinal chemistry.

Balancing the Stability–Activity Trade‐Off by Fine‐Tuning Dehalogenase Access Tunnels

Eva Sebestova, David Bednář, Jiří Damborský, 2015 .

Feasibility and constraints of particle targeting using the antigen–antibody interaction† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c3nr04340a Click here for additional data file.

V. Tokárová, F. Štěpánek, V. Král, 2013, Nanoscale.

Oligomeric interface modulation causes misregulation of purine 5´-nucleotidase in relapsed leukemia

V. Veverka, P. Man, P. Řezáčová, 2016, BMC Biology.

X-ray structure of human aldo–keto reductase 1C3 in complex with a bile acid fused tetrazole inhibitor: experimental validation, molecular docking and structural analysis

J. Brynda, Maja A. Marinović, E. Petri, 2022, RSC medicinal chemistry.

Optimization of the crystallizability of a single-chain antibody fragment.

V. Král, V. Veverka, P. Řezáčová, 2014, Acta crystallographica. Section F, Structural biology communications.

New techniques for membrane protein crystallization tested on photosystem II core complex of Pisum sativum

J. García‐Ruiz, P. Řezáčová, F. Vácha, 2007, Photosynthesis Research.

Potent inhibition of drug-resistant HIV protease variants by monoclonal antibodies.

V. Král, J. Konvalinka, J. Brynda, 2008, Antiviral research.

The structural basis for the selectivity of sulfonamido dicarbaboranes toward cancer-associated carbonic anhydrase IX

M. Havranek, V. Král, J. Brynda, 2020, Journal of enzyme inhibition and medicinal chemistry.

Structures of human cytosolic and mitochondrial nucleotidases: implications for structure-based design of selective inhibitors.

J. Brynda, P. Řezáčová, I. Rosenberg, 2014, Acta crystallographica. Section D, Biological crystallography.

Structure-based design of a bisphosphonate 5′(3′)-deoxyribonucleotidase inhibitor

J. Brynda, P. Řezáčová, M. Buděšínský, 2015 .

Structure of a single-chain Fv fragment of an antibody that inhibits the HIV-1 and HIV-2 proteases.

J. Lescar, J. Brynda, P. Řezáčová, 2003, Acta crystallographica. Section D, Biological crystallography.

Inhibition of HIV protease by monoclonal antibodies

J. Lescar, J. Brynda, P. Řezáčová, 2002, Journal of molecular recognition : JMR.

Anti-HIV proteinase monoclonal antibody F11.2.32 that inhibits enzyme activity.

J. Lescar, J. Brynda, P. Řezáčová, 1998, General physiology and biophysics.

Structure of the effector‐binding domain of deoxyribonucleoside regulator DeoR from Bacillus subtilis

Z. Otwinowski, M. Hubálek, P. Řezáčová, 2014, The FEBS journal.

Molecular Characterization of Clinical Isolates of Human Immunodeficiency Virus Resistant to the Protease Inhibitor Darunavir

J. Konvalinka, R. Kagan, J. Brynda, 2009, Journal of Virology.

Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir

Jana Václavíková, J. Konvalinka, R. Kagan, 2008, Protein science : a publication of the Protein Society.

B-H⋯π and C-H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides.

J. Brynda, P. Řezáčová, J. Holub, 2023, Physical Chemistry, Chemical Physics - PCCP.

Structure of the mouse galectin-4 N-terminal carbohydrate-recognition domain reveals the mechanism of oligosaccharide recognition.

J. Brynda, P. Malý, P. Řezáčová, 2011, Acta crystallographica. Section D, Biological crystallography.

Crystallization and preliminary X-ray diffraction analysis of mouse galectin-4 N-terminal carbohydrate recognition domain in complex with lactose.

J. Brynda, P. Malý, P. Řezáčová, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and diffraction analysis of β-N-acetylhexosaminidase from Aspergillus oryzae.

Ondřej Vaněk, Zdeněk Kukačka, J. Brynda, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Inhibitor–Polymer Conjugates as a Versatile Tool for Detection and Visualization of Cancer-Associated Carbonic Anhydrase Isoforms

V. Šubr, V. Král, J. Konvalinka, 2019, ACS Omega.

Ranking Power of the SQM/COSMO Scoring Function on Carbonic Anhydrase II-Inhibitor Complexes.

Ramachandran Gnanasekaran, J. Brynda, V. Veverka, 2018, Chemphyschem : a European journal of chemical physics and physical chemistry.

Structural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis

D. Svergun, V. Veverka, L. Bumba, 2017, Scientific Reports.

Mialostatin, a Novel Midgut Cystatin from Ixodes ricinus Ticks: Crystal Structure and Regulation of Host Blood Digestion

P. Řezáčová, J. Chmelař, J. Kotál, 2021, International journal of molecular sciences.

GS-8374, a Prototype Phosphonate-Containing Inhibitor of HIV-1 Protease, Effectively Inhibits Protease Mutants with Amino Acid Insertions

J. Konvalinka, J. Brynda, T. Cihlar, 2013, Journal of Virology.

Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus

J. Konvalinka, M. Kožíšek, P. Řezáčová, 2018, Viruses.

Complex of H275Y/I223V mutant variant of neuraminidase from H1N1 influenza virus with oseltamivir

J. Konvalinka, M. Kožíšek, P. Řezáčová, 2018 .

Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel.

U. Bornscheuer, J. Damborský, R. Ettrich, 2013, Angewandte Chemie.

In situ proteolysis of an N-terminal His tag with thrombin improves the diffraction quality of human aldo-keto reductase 1C3 crystals.

J. Brynda, Z. Voburka, E. Petri, 2018, Acta crystallographica. Section F, Structural biology communications.

Atomic resolution crystal structure of Sapp2p, a secreted aspartic protease from Candida parapsilosis.

I. Pichová, J. Brynda, L. Marečková, 2015, Acta crystallographica. Section D, Biological crystallography.

The crystal structure of protease Sapp1p from Candida parapsilosis in complex with the HIV protease inhibitor ritonavir

I. Pichová, J. Brynda, P. Řezáčová, 2012, Journal of enzyme inhibition and medicinal chemistry.

Crystal structure of rutinosidase from Aspergillus niger

J. Brynda, L. Biedermannová, P. Řezáčová, 2020 .

Development of a Crystallization Protocol for the DbeA1 Variant of Novel Haloalkane Dehalogenase from Bradyrhizobium elkani USDA94

Yukari Sato, J. Damborský, R. Chaloupkova, 2011 .

Crystallization and preliminary X-ray analysis of a novel haloalkane dehalogenase DbeA from Bradyrhizobium elkani USDA94.

Yukari Sato, J. Damborský, R. Chaloupkova, 2009, Acta Crystallographica. Section F : Structural Biology and Crystallization Communications.

Triggering HIV polyprotein processing by light using rapid photodegradation of a tight-binding protease inhibitor

J. Konvalinka, H. Kräusslich, B. Müller, 2015, Nature Communications.

Complex of H275Y/I223V mutant variant of neuraminidase from H1N1 influenza virus with oseltamivir

J. Konvalinka, M. Kožíšek, P. Řezáčová, 2018 .

Carborane-Based Carbonic Anhydrase Inhibitors: Insight into CAII/CAIX Specificity from a High-Resolution Crystal Structure, Modeling, and Quantum Chemical Calculations

P. Mader, J. Brynda, P. Hobza, 2014, BioMed research international.

Identification of carbonic anhydrase I immunodominant epitopes recognized by specific autoantibodies which indicate an improved prognosis in patients with malignancy after autologous stem cell transplantation.

P. Mader, Z. Bílková, P. Řezáčová, 2010, Journal of proteome research.

Structural characterization of two prototypical repressors of SorC family reveals tetrameric assemblies on DNA and mechanism of function

L. Krásný, P. Řezáčová, P. Pachl, 2024, Nucleic acids research.

Structure and function of bacterial transcription regulators of the SorC family.

P. Řezáčová, M. Šoltysová, 2024, Transcription.