Zhong-yu Hu

发表

A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71

Gwyndaf Evans, Zihe Rao, David I. Stuart, 2012, Nature Structural &Molecular Biology.

Neutralization of SARS-CoV-2 VOC 501Y.V2 by human antisera elicited by both inactivated BBIBP-CorV and recombinant dimeric RBD ZF2001 vaccines

G. Gao, Baoying Huang, W. Tan, 2021, bioRxiv.

Advances in aluminum hydroxide-based adjuvant research and its mechanism

Zhong-yu Hu, P. He, Yening Zou, 2015, Human vaccines & immunotherapeutics.

More powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules

D. Stuart, D. Rowlands, Z. Rao, 2014, Nature Structural &Molecular Biology.

Recombinant vaccine containing an RBD-Fc fusion induced protection against SARS-CoV-2 in nonhuman primates and mice

Hao Li, X. Wang, Yan Li, 2021, Cellular & Molecular Immunology.

Recombinant Fc-fusion vaccine of RBD induced protection against SARS-CoV-2 in non-human primate and mice

Yan Li, X. Fang, Yuwei Gao, 2020, bioRxiv.

Robust Antibody and Cytokine Response to Hepatitis B Vaccine Among Not-in-Treatment Patients With Chronic Hepatitis C: An Open-Label Control Study in China

Yi Feng, X. Fang, Li Li, 2017, The Journal of infectious diseases.

Enhanced specific immune responses by CpG DNA in mice immunized with recombinant hepatitis B surface antigen and HB vaccine

Zhenglun Liang, Zhong-yu Hu, Xingtai Wang, 2011, Virology Journal.

Analysis of immunological mechanisms exerted by HBsAg-HBIG therapeutic vaccine combined with Adefovir in chronic hepatitis B patients

Y. Wen, Zhong-yu Hu, S. Geng, 2017, Human vaccines & immunotherapeutics.

A randomized, double‐blind, placebo‐controlled phase 1 and phase 2 clinical trial to evaluate efficacy and safety of a SARS‐CoV‐2 vaccine SCoK in adults

X. Wang, Y. Li, X. Fang, 2022, Clinical and translational medicine.

A potent, broadly protective vaccine against SARS-CoV-2 variants of concern

X. Fang, L. Bao, Jiang Fan, 2022, npj Vaccines.

Immunogenicity and safety of the homogenous booster shot of a recombinant fusion protein vaccine (V-01) against COVID-19 in healthy adult participants primed with a two-dose regimen

Jianfeng He, X. Fang, yang-xin fu, 2021, medRxiv.

Immunogenicity and safety of a recombinant fusion protein vaccine (V-01) against coronavirus disease 2019 in healthy adults: a randomized, double-blind, placebo-controlled, phase II trial

Jianfeng He, F. Dèng, W. Guan, 2021, Chinese medical journal.

Safety and immunogenicity of a recombinant interferon-armed RBD dimer vaccine (V-01) for COVID-19 in healthy adults: a randomized, double-blind, placebo-controlled, Phase I trial

Jianfeng He, X. Fang, F. Dèng, 2021, Emerging microbes & infections.

Recombinant vaccine containing an RBD-Fc fusion induced protection against SARS-CoV-2 in nonhuman primates and mice

Yan Li, X. Fang, Yuwei Gao, 2021, Cellular & molecular immunology.

Significant transcriptome and cytokine changes in hepatitis B vaccine non-responders revealed by genome-wide comparative analysis

X. Zhai, X. Fang, Zhong-yu Hu, 2018, Human vaccines & immunotherapeutics.

Safety and immunogenicity of a protein subunit COVID-19 vaccine (ZF2001) in healthy children and adolescents aged 3–17 years in China: a randomised, double-blind, placebo-controlled, phase 1 trial and an open-label, non-randomised, non-inferiority, phase 2 trial

Zhong-yu Hu, Xilu Wang, Z. Ying, 2023, The Lancet Child & Adolescent Health.

Efficacy and Safety of the RBD-Dimer–Based Covid-19 Vaccine ZF2001 in Adults

Ibrokhim Y. Abdurakhmonov, Jinghua Yan, D. Dalimova, 2022, The New England journal of medicine.

Design of a mutation-integrated trimeric RBD with broad protection against SARS-CoV-2

Zhixin Ma, Shi Chen, Zhong-yu Hu, 2022, Cell Discovery.

Design of a mutation-integrated trimeric RBD with broad protection against SARS-CoV-2

Zhixin Ma, Shi Chen, Zhong-yu Hu, 2022, Cell discovery.

Development of recombinant COVID-19 vaccine based on CHO-produced, prefusion spike trimer and alum/CpG adjuvants

Chao Zhang, Yunqi Yang, Jianqing Xu, 2021, Vaccine.

Structure and computation-guided design of a mutation-integrated trimeric RBD candidate vaccine with broad neutralization against SARS-CoV-2

Wei-min Zhou, Zhixin Ma, Wei Huang, 2021, bioRxiv.

Safety and immunogenicity of a recombinant tandem-repeat dimeric RBD-based protein subunit vaccine (ZF2001) against COVID-19 in adults: two randomised, double-blind, placebo-controlled, phase 1 and 2 trials

Yan Liu, G. Gao, Jinghua Yan, 2021, The Lancet Infectious Diseases.

Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity

D. Stuart, Z. Rao, Xiangxi Wang, 2015, Journal of Virology.

Biodegradable polylactide microspheres enhance specific immune response induced by Hepatitis B surface antigen

Guanghui Ma, X. Fang, G. Ma, 2014, Human vaccines & immunotherapeutics.

Hepatitis A virus and the origins of picornaviruses

Qiang Gao, Zihe Rao, David I. Stuart, 2014, Nature.

Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site

D. Stuart, Z. Rao, T. Walter, 2017, Proceedings of the National Academy of Sciences.

Serum sample neutralisation of BBIBP-CorV and ZF2001 vaccines to SARS-CoV-2 501Y.V2

G. Gao, Baoying Huang, W. Tan, 2021, The Lancet Microbe.

The antigenicity of SARS-CoV-2 Delta variants aggregated 10 high-frequency mutations in RBD has not changed sufficiently to replace the current vaccine strain

Hao Song, Qihui Wang, J. Nie, 2022, Signal Transduction and Targeted Therapy.

Near-atomic structure of Japanese encephalitis virus reveals critical determinants of virulence and stability

D. Stuart, Z. Rao, J. Huiskonen, 2017, Nature Communications.

Safety and immunogenicity of a bivalent SARS-CoV-2 recombinant protein vaccine, SCTV01C in unvaccinated adults: A randomized, double-blinded, placebo-controlled, phase I clinical trial

Tianzuo Zhang, Zhong-yu Hu, Yi-min Cui, 2022, Journal of Infection.

[Study on the kinesis of cellular immunity in adults vaccinated with recombinant hepatitis B vaccine].

X. Zhai, F. Zhu, Zhong-yu Hu, 2007, Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi.

Research Progress of Aluminum Phosphate Adjuvants and Their Action Mechanisms

Zhong-yu Hu, P. He, Yening Zou, 2023, Pharmaceutics.

Safety and immunogenicity of a recombinant interferon-armed RBD dimer vaccine (V-01) for COVID-19 in healthy adults: a randomized, double-blind, placebo-controlled, Phase I trial

Jianfeng He, X. Fang, F. Dèng, 2021, Emerging Microbes & Infections.

Safety and immunogenicity of a recombinant tandem-repeat dimeric RBD protein vaccine against COVID-19 in adults: pooled analysis of two randomized, double-blind, placebo-controlled, phase 1 and 2 trials

Yan Liu, G. Gao, X. Fang, 2020, medRxiv.