M. Cliff

发表

Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF 3 - rather than by phosphoranes

N. J. Baxter, A. Hounslow, J. Waltho, 2010, Proceedings of the National Academy of Sciences.

Transition state analogue structures of human phosphoglycerate kinase establish the importance of charge balance in catalysis.

Matthew W Bowler, N. J. Baxter, A. Hounslow, 2010, Journal of the American Chemical Society.

Proteoglycans and their heterogeneous glycosaminoglycans at the atomic scale.

B. Sattelle, M. Cliff, J. Shakeri, 2015, Biomacromolecules.

Mapping Hidden Residual Structure within the Myc bHLH-LZ Domain Using Chemical Denaturant Titration.

M. Blackledge, J. Nissink, M. R. Jensen, 2019, Structure.

Near attack conformers dominate β-phosphoglucomutase complexes where geometry and charge distribution reflect those of substrate

C. E. Webster, N. J. Baxter, A. Hounslow, 2012, Proceedings of the National Academy of Sciences.

Real-time pure shift 15N HSQC of proteins: a real improvement in resolution and sensitivity

M. Foroozandeh, M. Nilsson, G. Morris, 2015, Journal of Biomolecular NMR.

Simultaneously Enhancing Spectral Resolution and Sensitivity in Heteronuclear Correlation NMR Spectroscopy

M. Foroozandeh, M. Nilsson, G. Morris, 2013, Angewandte Chemie.

Nonequivalence of Second Sphere “Noncatalytic” Residues in Pentaerythritol Tetranitrate Reductase in Relation to Local Dynamics Linked to H-Transfer in Reactions with NADH and NADPH Coenzymes

N. Scrutton, N. J. Baxter, J. Waltho, 2018, ACS catalysis.

Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining

H. Mootz, J. Stark, S. Jackson, 2022, Nucleic acids research.

Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining

S. Jackson, C. Loch, C. K. Schmidt, 2021, bioRxiv.

Structural and biochemical characterisation of the prenylated flavin mononucleotide-dependent indole-3-carboxylic acid decarboxylase.

K. Fisher, M. Cliff, D. Leys, 2022, The Journal of biological chemistry.

A Kinetic Model of Intermediate Formation during Assembly of Cholera Toxin B-subunit Pentamers*

A. Clarke, C. Lesieur, T. Hirst, 2002, The Journal of Biological Chemistry.

The role of conserved residues in Fdc decarboxylase in prenylated flavin mononucleotide oxidative maturation, cofactor isomerization, and catalysis

K. Fisher, D. Parker, M. Cliff, 2017, The Journal of Biological Chemistry.

Structural Basis for Selective Interaction between the ESCRT Regulator HD-PTP and UBAP1

L. Tabernero, J. Bella, P. Woodman, 2016, Structure.

Crystal structure of tobacco etch virus protease shows the protein C terminus bound within the active site.

R. George, C. M. Nunn, S. Djordjević, 2005, Journal of molecular biology.

Prioritization of charge over geometry in transition state analogues of a dual specificity protein kinase.

N. J. Baxter, A. Hounslow, J. Waltho, 2011, Journal of the American Chemical Society.

α-Fluorophosphonates reveal how a phosphomutase conserves transition state conformation over hexose recognition in its two-step reaction

N. J. Baxter, J. Waltho, M. Bowler, 2014, Proceedings of the National Academy of Sciences.

Volume-sensitive taurine efflux from mammary tissue is not obliged to utilize volume-activated anion channels

M. Cliff, D. Shennan, P. Hawkins, 1996, Bioscience reports.

A survey of the year 2002 literature on applications of isothermal titration calorimetry.

J. Ladbury, M. Cliff, 2003, Journal of molecular recognition : JMR.

A role for tungsten in the biology of Campylobacter jejuni: tungstate stimulates formate dehydrogenase activity and is transported via an ultra‐high affinity ABC system distinct from the molybdate transporter

M. Cliff, D. Kelly, J. Smart, 2009, Molecular microbiology.

Making the longest sugars: a chemical synthesis of heparin-related [4]n oligosaccharides from 16-mer to 40-mer† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc02091c

G. Jayson, J. Gardiner, M. Cliff, 2015, Chemical science.

A Chiral 19F NMR Reporter of Foldamer Conformation in Bilayers

I. Vitorica-Yrezabal, M. Cliff, G. Whitehead, 2022, Journal of the American Chemical Society.

Why did Nature select phosphate for its dominant roles in biology

J. Waltho, M. Bowler, M. Cliff, 2010 .

Molecular basis for TPR domain‐mediated regulation of protein phosphatase 5

D. Barford, Mark A. Williams, J. Ladbury, 2005, The EMBO journal.

Fhit proteins can also recognize substrates other than dinucleoside polyphosphates

W. Stec, A. Guranowski, M. Cliff, 2008, FEBS letters.

1H, 13C, 15N backbone resonance assignment for the 1–164 construct of human XRCC4

C. K. Schmidt, M. Cliff, M. J. Cabello-Lobato, 2021, Biomolecular NMR Assignments.

Allomorphy as a mechanism of post-translational control of enzyme activity

C. R. Trevitt, N. J. Baxter, A. Hounslow, 2020, Nature Communications.

The CouPSTU and TarPQM Transporters in Rhodopseudomonas palustris: Redundant, Promiscuous Uptake Systems for Lignin-Derived Aromatic Substrates

J. Rafferty, M. Cliff, D. Kelly, 2013, PloS one.

Domain rotations between open, closed and bullet-shaped forms of the thermosome, an archaeal chaperonin.

H. Saibil, A. Clarke, G. Schoehn, 2000, Journal of molecular biology.

A kinetic analysis of the nucleotide-induced allosteric transitions of GroEL.

A. Clarke, S. Burston, N. Hay, 1999, Journal of molecular biology.

Asymmetry, commitment and inhibition in the GroE ATPase cycle impose alternating functions on the two GroEL rings.

A. Clarke, M. Cliff, N. Kad, 1998, Journal of molecular biology.

Spinning sugars in antigen biosynthesis: a direct study of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases

M. Rejžek, R. Field, S. Nepogodiev, 2021, bioRxiv.

Structural effects of the highly protective V127 polymorphism on human prion protein

J. Collinge, G. Jackson, D. Sangar, 2020, Communications Biology.

Structural effects of the highly protective V127 polymorphism on human prion protein

J. Collinge, G. Jackson, D. Sangar, 2020, Communications Biology.

Isotopically labeled flavoenzymes and their uses in probing reaction mechanisms.

N. Scrutton, J. Waltho, M. Cliff, 2019, Methods in enzymology.

Myc phosphorylation in its basic helix–loop–helix region destabilizes transient α-helical structures, disrupting Max and DNA binding

J. Nissink, J. Waltho, M. Cliff, 2018, The Journal of Biological Chemistry.

Low Energy Pathways and Non-native Interactions

A. Clarke, R. Sessions, M. Cliff, 2005, Journal of Biological Chemistry.

An Enzyme with High Catalytic Proficiency Utilizes Distal Site Substrate Binding Energy to Stabilize the Closed State but at the Expense of Substrate Inhibition

N. J. Baxter, A. Hounslow, J. Waltho, 2022, ACS catalysis.

Elucidation of Steps in the Capture of a Protein Substrate for Efficient Encapsulation by GroE *

A. Clarke, S. Burston, M. Cliff, 2006, Journal of Biological Chemistry.

Nonequilibrium self-association of a cpn60 chaperonin induced by tryptophan mutation

A. Clarke, S. Harding, M. Cliff, 1999 .

Characterizing monoclonal antibody formulations in arginine glutamate solutions using 1H NMR spectroscopy

Shahid Uddin, Alexander P. Golovanov, C. F. van der Walle, 2016, mAbs.

Molecular recognition via coupled folding and binding in a TPR domain.

D. Barford, Mark A. Williams, J. Ladbury, 2005, Journal of molecular biology.

Conformational changes in the AAA ATPase p97–p47 adaptor complex

R. Isaacson, P. Freemont, J. Ladbury, 2006, The EMBO journal.

Structural tightening and interdomain communication in the catalytic cycle of phosphoglycerate kinase.

M. Reed, A. Hounslow, J. Waltho, 2010, Journal of molecular biology.

Charge-balanced metal fluoride complexes for protein kinase A with adenosine diphosphate and substrate peptide SP20.

N. J. Baxter, A. Hounslow, J. Waltho, 2012, Angewandte Chemie.

Equatorial Active Site Compaction and Electrostatic Reorganization in Catechol-O-methyltransferase

N. Scrutton, L. Johannissen, N. J. Baxter, 2019, ACS catalysis.

Trp203 mutation in GroEL promotes a self-association reaction: a hydrodynamic study

A. Clarke, S. Harding, P. Lund, 2000, European Biophysics Journal.

The denatured state under native conditions: a non-native-like collapsed state of N-PGK.

M. Reed, A. Clarke, A. Hounslow, 2006, Journal of molecular biology.

Enzymatic properties of the lactate dehydrogenase enzyme from Plasmodium falciparum

A. Clarke, R. Sessions, D. Shoemark, 2007, The FEBS journal.

Conformational diversity in the TPR domain-mediated interaction of protein phosphatase 5 with Hsp90.

D. Barford, Mark A. Williams, J. Ladbury, 2006, Structure.

Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases

M. Rejžek, R. Field, S. Nepogodiev, 2022, The Journal of biological chemistry.

Enzymatic Carboxylation of 2-Furoic Acid Yields 2,5-Furandicarboxylic Acid (FDCA)

K. Fisher, D. Parker, M. Cliff, 2019, ACS catalysis.

1H, 15N and 13C backbone resonance assignments of pentaerythritol tetranitrate reductase from Enterobacter cloacae PB2

N. Scrutton, N. J. Baxter, J. Waltho, 2017, Biomolecular NMR assignments.

Molecular architecture of the tyrosine phosphatase HD-PTP and the structural basis for its specific interaction with UBAP1

Bella, L. Tabernero, T. Jowitt, 2018 .

Assessing the Influence of Mutation on GTPase Transition States by Using X‐ray Crystallography, 19F NMR, and DFT Approaches

N. Richards, J. Waltho, M. Bowler, 2017, Angewandte Chemie.

Redox-state-dependent complex formation between pseudoazurin and nitrite reductase.

J. Ladbury, M. Ubbink, A. Impagliazzo, 2007, Journal of the American Chemical Society.

Beyond the EX1 limit: probing the structure of high-energy states in protein unfolding.

A. Clarke, R. Sessions, J. Waltho, 2004, Journal of molecular biology.

Mapping local structural perturbations in the native state of stefin B (cystatin B) under amyloid forming conditions

A. Hounslow, J. Waltho, M. Cliff, 2012, Front. Mol. Neurosci..

Anionic charge is prioritized over geometry in aluminum and magnesium fluoride transition state analogs of phosphoryl transfer enzymes.

F. Hollfelder, D. Wemmer, N. J. Baxter, 2008, Journal of the American Chemical Society.

A survey of the year 2003 literature on applications of isothermal titration calorimetry

J. Ladbury, M. Cliff, A. Gutierrez, 2004, Journal of molecular recognition : JMR.

Assessing the Influence of Mutation on GTPase Transition States by Using X‐ray Crystallography, 19F NMR, and DFT Approaches

N. Richards, J. Waltho, M. Bowler, 2017, Angewandte Chemie.

A thiol labelling competition experiment as a probe for sidechain packing in the kinetic folding intermediate of N-PGK.

J. Waltho, Tooba Alizadeh, M. Cliff, 2006, Journal of molecular biology.

1H, 15N, 13C backbone resonance assignments of human soluble catechol O-methyltransferase in complex with S-adenosyl-l-methionine and 3,5-dinitrocatechol

N. Scrutton, N. J. Baxter, J. Waltho, 2016, Biomolecular NMR Assignments.

The Relationship between Enzyme Conformational Change, Proton Transfer, and Phosphoryl Transfer in β-Phosphoglucomutase

P. Popelier, J. Waltho, M. Cliff, 2021, ACS Catalysis.

van der Waals Contact between Nucleophile and Transferring Phosphorus Is Insufficient To Achieve Enzyme Transition-State Architecture

L. A. Johnson, C. R. Trevitt, N. J. Baxter, 2018, ACS Catalysis.

1H, 15N, 13C backbone resonance assignments of human phosphoglycerate kinase in a transition state analogue complex with ADP, 3-phosphoglycerate and magnesium trifluoride

N. J. Baxter, J. Waltho, M. Cliff, 2017, Biomolecular NMR Assignments.

Transition state analogue structures of human phosphoglycerate kinase establish the importance of charge balance in catalysis.

N. J. Baxter, A. Hounslow, J. Waltho, 2010, Journal of the American Chemical Society.

Anionic charge is prioritized over geometry in aluminum and magnesium fluoride transition state analogs of phosphoryl transfer enzymes.

F. Hollfelder, N. J. Baxter, A. Hounslow, 2008, Journal of the American Chemical Society.

Deposited in DRO : 15 October 2015 Version of attached le : Published Version Peer-review status of attached le : Peer-reviewed Citation for published item :

M. Foroozandeh, M. Nilsson, J. Waltho, 2014 .

Photocobilins integrate B12 and bilin photochemistry for enzyme control

L. Johannissen, M. Cliff, M. Sakuma, 2024, Nature communications.

Fhit proteins can also recognize substrates other than dinucleoside polyphosphates

W. Stec, A. Guranowski, M. Cliff, 2008, FEBS letters.