P. Högger

发表

Validation of a liquid chromatography assay for the quantification of the Raf kinase inhibitor BAY 43-9006 in small volumes of mouse serum.

U. Rapp, S. Afify, P. Högger, 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Comparative permeability and diffusion kinetics of cyclosporine A liposomes and propylene glycol solution from human lung tissue into human blood ex vivo.

P. Högger, E. Haltner-Ukomadu, Beatrice Trammer, 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Inhibition of NF-κB activation and MMP-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract (Pycnogenol)

J. Muchova, Z. Ďuračková, P. Högger, 2006, Journal of Inflammation.

Relationship Between Amphetamine Concentrations in Saliva and Serum in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder

M. Gerlach, M. Romanos, P. Högger, 2020, Therapeutic drug monitoring.

Binding kinetics of fluticasone propionate to the human glucocorticoid receptor

P. Högger, P. Rohdewald, 1994, Steroids.

Constituents and Metabolites of a French Oak Wood Extract (Robuvit®) in Serum and Blood Cell Samples of Women Undergoing Hysterectomy

Z. Ďuračková, P. Högger, O. Scherf-Clavel, 2020, Frontiers in Pharmacology.

Coronary heart disease Effects of Pycnogenol on endothelial function in patients with stable coronary artery disease : a double-blind , randomized , placebo-controlled , cross-over study

F. Ruschitzka, T. Lüscher, G. Noll, 2012 .

Scavenger Receptor Cysteine-Rich Family Glucocorticoid-Inducible Member of the Protein RM 3 / 1 on Human Monocytes as a Identification of the Integral Membrane Clemens

P. Högger, F. Buck, J. Dreier, 1998 .

Highly sensitive analysis of polyphenols and their metabolites in human blood cells using dispersive SPE extraction and LC-MS/MS

P. Högger, Melanie Mülek, 2015, Analytical and Bioanalytical Chemistry.

Fluorescence interference of polyphenols in assays screening for dipeptidyl peptidase IV inhibitory activity

P. Högger, Stoyan Dirimanov, 2020 .

Screening of Inhibitory Effects of Polyphenols on Akt-Phosphorylation in Endothelial Cells and Determination of Structure-Activity Features

P. Högger, Stoyan Dirimanov, 2019, Biomolecules.

Distribution of Constituents and Metabolites of Maritime Pine Bark Extract (Pycnogenol®) into Serum, Blood Cells, and Synovial Fluid of Patients with Severe Osteoarthritis: A Randomized Controlled Trial

P. Högger, L. Seefried, F. Genest, 2017, Nutrients.

Facilitated Uptake of a Bioactive Metabolite of Maritime Pine Bark Extract (Pycnogenol) into Human Erythrocytes

P. Högger, M. Kurlbaum, Melanie Mülek, 2013, PloS one.

Facilitated cellular uptake and suppression of inducible nitric oxide synthase by a metabolite of maritime pine bark extract (Pycnogenol).

P. Högger, Klaus Uhlenhut, 2012, Free radical biology & medicine.

Inhibition of COX-1 and COX-2 activity by plasma of human volunteers after ingestion of French maritime pine bark extract (Pycnogenol).

J. Muchova, Z. Ďuračková, P. Högger, 2006, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Oxidative stress and 8-iso-prostaglandin F2α induce ectodomain shedding of CD163 and release of tumor necrosis factor-α from human monocytes

P. Högger, Meike Timmermann, 2005 .

Oxidative stress and 8-iso-prostaglandin F(2alpha) induce ectodomain shedding of CD163 and release of tumor necrosis factor-alpha from human monocytes.

P. Högger, Meike Timmermann, 2005, Free radical biology & medicine.

Stability of dietary polyphenols under the cell culture conditions: avoiding erroneous conclusions.

Jianbo Xiao, P. Högger, 2015, Journal of agricultural and food chemistry.

Methacholine delays pulmonary absorption of inhaled β(2)-agonists due to competition for organic cation/carnitine transporters.

P. Högger, M. Bayliss, G. Friedel, 2012, Pulmonary pharmacology & therapeutics.

Monitoring the initial pulmonary absorption of two different beclomethasone dipropionate aerosols employing a human lung reperfusion model

A. Kirschbaum, P. Fritz, P. Högger, 2005, Respiratory research.

Metabolism of dietary flavonoids in liver microsomes.

Jianbo Xiao, P. Högger, 2013, Current drug metabolism.

Dietary polyphenols and type 2 diabetes: current insights and future perspectives.

Jianbo Xiao, P. Högger, J. Xiao, 2014, Current medicinal chemistry.

Effects of Pycnogenol on Endothelial Function in Patients with Stable Coronary Artery Disease-A Double-blind , Randomized , Placebo-controlled , Crossover Study Pycnogenol improves endothelial function

F. Ruschitzka, T. Lüscher, G. Noll, 2017 .

Human receptor kinetics and lung tissue retention of the enhanced-affinity glucocorticoid fluticasone furoate

P. Högger, Anagnostis Valotis, 2007, Respiratory research.

Binding kinetics of budesonide to the human glucocorticoid receptor.

P. Högger, P. Rohdewald, N. Esmailpour, 1998, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Regioselective synthesis of 7-O-esters of the flavonolignan silibinin and SARs lead to compounds with overadditive neuroprotective effects.

M. Decker, R. Sabaté, P. Maher, 2018, European journal of medicinal chemistry.

Dose response and therapeutic index of inhaled corticosteroids in asthma

P. Högger, 2003, Current opinion in pulmonary medicine.

Distribution of inhaled fluticasone propionate between human lung tissue and serum in vivo.

K. Rabe, P. Högger, P. Rohdewald, 1997, The European respiratory journal.

Dissolution in nasal fluid, retention and anti‐inflammatory activity of fluticasone furoate in human nasal tissue ex vivo

C. Bachert, P. Högger, D. Baumann, 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Surfactant Protein A (SP-A) and Angiotensin Converting Enzyme (ACE) as Early Biomarkers for Pulmonary Edema Formation in Ventilated Human Lung Lobes

P. Högger, Michael Schmidt, M. Gnadt, 2012, Lung.

Biochemical Characterization of a Glucocorticoid-Induced Membrane Protein (RM3/1) in Human Monocytes and Its Application as Model System for Ranking Glucocorticoid Potency

P. Högger, P. Rohdewald, C. Sorg, 1998, Pharmaceutical Research.

Stability profiling and degradation products of dihydromyricetin in Dulbecco's modified eagle's medium.

J. Simal-Gándara, P. Högger, V. Bajpai, 2022, Food chemistry.

The influence of methotrexate on the gene expression of the pro-inflammatory cytokine IL-12A in the therapy of rheumatoid arthritis.

M. Kalipciyan, R. Mader, P. Högger, 2011, Clinical and experimental rheumatology.

A short-chain methotrexate polyglutamate as outcome parameter in rheumatoid arthritis patients receiving methotrexate.

B. Rizovski, R. Mader, P. Högger, 2012, Clinical and experimental rheumatology.

Molecular modeling of G-protein coupled receptor kinase 2: Docking and biochemical evaluation of inhibitors

Daniel A. Gschwend, K. Kameyama, W. Sadee, 2000, AAPS PharmSci.

[Mechanism of action of nasal glucocorticosteroids in the treatment of allergic rhinitis. Part 2: Practical aspects of application].

O. Pfaar, L. Klimek, P. Högger, 2012, HNO.

Significant receptor affinities of metabolites and a degradation product of mometasone furoate

P. Högger, Anagnostis Valotis, 2004, Respiratory research.

Human receptor kinetics, tissue binding affinity, and stability of mometasone furoate.

P. Högger, O. Elert, K. Neukam, 2004, Journal of pharmaceutical sciences.

Comparison of the Tissue Affinity of Glucocorticoids to Human Lung, Nasal and Skin Tissue in vitro

P. Högger, 2001, Arzneimittelforschung.

Oligomeric procyanidins of French maritime pine bark extract (Pycnogenol) effectively inhibit alpha-glucosidase.

P. Högger, A. Schäfer, 2007, Diabetes research and clinical practice.

Interaction of soluble CD163 with activated T lymphocytes involves its association with non‐muscle myosin heavy chain type A

P. Högger, F. Buck, C. Sorg, 2004, Immunology and cell biology.

Determination of Guanfacine in Oral Fluid and Serum of Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: A Short Communication

M. Gerlach, M. Romanos, P. Högger, 2021, Therapeutic drug monitoring.

Design, synthesis and biological activity of azasugar-based CD163 ectodomain shedding inhibitors

P. Högger, M. Attia, C. Herdeis, 2007 .

Analgesic and antiinflammatory activity of Morinda citrifolia L. (Noni) fruit

P. Högger, J. Westendorf, Klaus Uhlenhut, 2010, Phytotherapy research : PTR.

Antioxidant activity and inhibition of matrix metalloproteinases by metabolites of maritime pine bark extract (pycnogenol).

P. Högger, Tanja Grimm, A. Schäfer, 2004, Free radical biology & medicine.

The muscarinic acetylcholine receptors

W. Sadee, J. Lameh, P. Högger, 1996 .

Regulation of CD163 on human macrophages: cross‐linking of CD163 induces signaling and activation

R. Beelen, P. Högger, E. Döpp, 1999, Journal of leukocyte biology.

Plasma protein binding of polyphenols from maritime pine bark extract (USP).

P. Högger, M. Kurlbaum, 2011, Journal of pharmaceutical and biomedical analysis.

The algal polysaccharide ulvan suppresses growth of hepatoma cells

J. Simal-Gándara, Jianbo Xiao, Chao Zhao, 2020, Food Frontiers.

Nutrition-derived bioactive metabolites produced by gut microbiota and their potential impact on human health

P. Högger, 2013 .

Human monocytes express CD163, which is upregulated by IL-10 and identical to p155.

P. Wallace, P. Högger, M. Stehling, 2000, Cytokine.

Activating and Inactivating Mutations in N- and C-terminal i3 Loop Junctions of Muscarinic Acetylcholine Hm1 Receptors (*)

W. Sadee, J. Lameh, P. Högger, 1995, The Journal of Biological Chemistry.

Soluble CD163 inhibits phorbol ester-induced lymphocyte proliferation.

P. Högger, C. Sorg, 2001, Biochemical and biophysical research communications.

Analysis of metformin, sitagliptin and creatinine in human dried blood spots.

P. Högger, M. Scherf-Clavel, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Cellular pharmacodynamic effects of Pycnogenol® in patients with severe osteoarthritis: a randomized controlled pilot study

D. Salter, P. Högger, L. Seefried, 2017, BMC Complementary and Alternative Medicine.

Hydrophobic amino acid in the i2 loop plays a key role in receptor-G protein coupling.

W. Sadee, J. Lameh, P. Högger, 1993, The Journal of biological chemistry.

A randomized, double-blind, parallel, single-site pilot trial to compare two different starting doses of methotrexate in methotrexate-naïve adult patients with rheumatoid arthritis.

R. Mader, P. Högger, B. Jilma, 2012, Clinical therapeutics.

Effects of Pycnogenol on endothelial function in patients with stable coronary artery disease: a double-blind, randomized, placebo-controlled, cross-over study.

F. Ruschitzka, T. Lüscher, G. Noll, 2012, European heart journal.

Identification of the integral membrane protein RM3/1 on human monocytes as a glucocorticoid-inducible member of the scavenger receptor cysteine-rich family (CD163).

P. Högger, F. Buck, J. Dreier, 1998, Journal of immunology.

Shedding of CD163, a novel regulatory mechanism for a member of the scavenger receptor cysteine-rich family.

P. Högger, C. Sorg, A. Droste, 1999, Biochemical and biophysical research communications.

Binding of Glucocorticoids to Human Nasal Tissue in vitro

P. Högger, P. Rohdewald, N. Esmailpour, 2000, International Archives of Allergy and Immunology.

Stability and antioxidant capacity of epigallocatechin gallate in Dulbecco's modified eagle medium.

J. Simal-Gándara, Lunzhao Yi, M. Prieto, 2021, Food chemistry.

Influence of diabetes on the pharmacokinetic behavior of natural polyphenols.

Jianbo Xiao, P. Högger, 2014, Current drug metabolism.

Investigation of new products and reaction kinetics for myricetin in DMEM via an in situ UPLC–MS–MS analysis

J. Simal-Gándara, Lunzhao Yi, M. Prieto, 2020 .

Stability of quercetin in DMEM and cell culture with A549 cells

J. Simal-Gándara, M. Prieto, Jianbo Xiao, 2022, eFood.

Pharmacokinetics of bromfenac in healthy subjects after single oral administration of three different doses.

P. Högger, P Högger, P. Rohdewald, 1993, Arzneimittel-Forschung.

Suppression of Cytokine Release by Fluticasone Furoate vs. Mometasone Furoate in Human Nasal Tissue Ex-Vivo

C. Bachert, G. Holtappels, Luo Zhang, 2014, PloS one.

Insulin-like growth factor-I aerosol formulations for pulmonary delivery.

L. Meinel, Isabel Schultz, M. Beck-Broichsitter, 2013, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Pitfalls and limitations in using 4,5-diaminofluorescein for evaluating the influence of polyphenols on nitric oxide release from endothelial cells.

P. Högger, Klaus Uhlenhut, 2012, Free radical biology & medicine.

Current Concepts for Optimizing the Therapeutic Index of Glucocorticoid Receptor Ligands for Oral and Inhalative Use: Basic Considerations and Clinical Reality

P. Högger, Petra Högger, 2003 .

Single and multiple dose pharmacokinetics of maritime pine bark extract (Pycnogenol) after oral administration to healthy volunteers

J. Muchova, Z. Ďuračková, P. Högger, 2006, BMC clinical pharmacology.

Development of an in vitro model to assess deposition of aerosol particles in a representative replica of the rat's respiratory tract.

P. Högger, D. Prime, P. Burnell, 2012, Journal of aerosol medicine and pulmonary drug delivery.

Investigations into neuroprotectivity, stability, and water solubility of 7‐O‐cinnamoylsilibinin, its hemisuccinate and dehydro derivatives

M. Decker, L. Meinel, P. Högger, 2018, Archiv der Pharmazie.

Rapid method for isolation of total RNA from eukaryotic cell lines and leukocytes.

P. Högger, C. Sorg, J. Dreier, 1998, DNA and cell biology.

Dried blood spot testing for estimation of renal function and analysis of metformin and sitagliptin concentrations in diabetic patients: a cross-sectional study

P. Högger, M. Scherf-Clavel, Anagnostis Valotis, 2019, European Journal of Clinical Pharmacology.

Development of a novel model for comparative evaluation of intranasal pharmacokinetics and effects of anti-allergic nasal sprays.

Claus Bachert, Daniel Baumann, C. Bachert, 2012, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Comparison of tilidine/naloxone, tramadol and bromfenac in experimental pain: a double-blind randomized crossover study in healthy human volunteers.

P. Högger, P. Rohdewald, 1999, International journal of clinical pharmacology and therapeutics.

Comparison of the bronchodilating effects of inhaled β₂-agonists after methacholine challenge in a human lung reperfusion model.

P. Högger, M. Bayliss, Chris D. Edwards, 2012, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Flavonols with a catechol or pyrogallol substitution pattern on ring B readily form stable dimers in phosphate buffered saline at four degrees celsius.

Jianbo Xiao, H. Cao, P. Högger, 2019, Food chemistry.

Insulin-like growth factor-I aerosol formulations for pulmonary delivery.

L. Meinel, Isabel Schultz, M. Beck-Broichsitter, 2013, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Dried blood spot testing for estimation of renal function and analysis of metformin and sitagliptin concentrations in diabetic patients: a cross-sectional study

P. Högger, Anagnostis Valotis, T. Hickethier, 2019, European Journal of Clinical Pharmacology.