D. Kozbor

发表

Targeting CXCL12/CXCR4 signaling with oncolytic virotherapy disrupts tumor vasculature and inhibits breast cancer metastases

M. Seshadri, S. Abrams, M. Gil, 2013, Proceedings of the National Academy of Sciences.

Recruitment of Intratumoral CD103+ Dendritic Cells by a CXCR4 Antagonist-Armed Virotherapy Enhances Antitumor Immunity

M. Opyrchal, K. Odunsi, H. Rokita, 2019, Molecular therapy oncolytics.

AWARD NUMBER: W81XWH-16-1-0146 TITLE: CXCR4 Antagonist as an Adjuvant in Immunotherapy of Epithelial Ovarian Cancer PRINCIPAL INVESTIGATOR:

D. Kozbor, 2017 .

Immunization with a Mimotope of GD2 Ganglioside Induces CD8+ T Cells That Recognize Cell Adhesion Molecules on Tumor Cells1

H. Rokita, J. Lau, M. Gil, 2008, The Journal of Immunology.

Targeting a Mimotope Vaccine to Activating Fcγ Receptors Empowers Dendritic Cells to Prime Specific CD8+ T Cell Responses in Tumor-Bearing Mice1

H. Rokita, M. Gil, D. Kozbor, 2009, The Journal of Immunology.

Amplification of the c-myc oncogene in one of five human breast carcinoma cell lines.

D. Kozbor, C. Croce, 1984, Cancer research.

Competitor mRNA fragments for quantitation of cytokine specific transcripts in cell lysates.

Z. Wang, M. Wang, D. Kozbor, 1993, Molecular immunology.

The production of monoclonal antibodies from human lymphocytes.

J. Roder, D. Kozbor, Danuta Kozbor, 1983, Immunology today.

Immunization strategies to augment oral vaccination with DNA and viral vectors expressing HIV envelope glycoprotein.

D. Kozbor, A. Wierzbicki, Y. Kaneko, 2002, Vaccine.

Oral vaccination with modified vaccinia virus Ankara attached covalently to TMPEG-modified cationic liposomes overcomes pre-existing poxvirus immunity from recombinant vaccinia immunization.

D. Kozbor, Y. Kaneko, T. Naito, 2007, The Journal of general virology.

Delivery Gene IL-15 and IL-21 Combined with Expressing the HIV-1 Env Glycoprotein when Immune Responses Induced by DNA Vaccine Increased Level and Longevity of Protective

L. Stamatatos, P. Shrikant, D. Kozbor, 2006 .

Comparative phenotypic analysis of available human hybridoma fusion partners.

J. Roder, S. Cole, D. Kozbor, 1986, Methods in enzymology.

Strategies for Production of Human Monoclonal Antibodies

J. Roder, S. Cole, D. Kozbor, 1985 .

Fusion Partners for Production of Human Monoclonal Antibodies

D. Kozbor, C. Croce, 1985 .

Tumor-Bearing Mice T Cell Responses in + Prime Specific CD8 Receptors Empowers Dendritic Cells to g FcTargeting a Mimotope Vaccine to Activating

H. Rokita, M. Gil, D. Kozbor, 2009 .

Expression of a translocated c-abl gene in hybrids of mouse fibroblasts and chronic myelogenous leukaemia cells

O. Witte, L. Showe, J. Konopka, 1986, Nature.

Inhibition of T cell antigen receptor-dependent phosphorylation of CD4 in human immunodeficiency virus type 1 infected cells.

J. Hoxie, L. Brass, D. Kozbor, 1992, Journal of Biological Chemistry.

A human hybrid myeloma for production of human monoclonal antibodies.

J. Roder, D. Kozbor, P. Tripputi, 1984, Journal of immunology.

Requirements for the establishment of high-titered human monoclonal antibodies against tetanus toxoid using the Epstein-Barr virus technique.

J. Roder, D. Kozbor, 1981, Journal of immunology.

and Targeting Cancer-Initiating Cells Growth by Decreasing Immunosuppression Virotherapy Inhibits Ovarian Cancer CXCL12/CXCR4 Blockade by Oncolytic

M. Seshadri, M. Opyrchal, H. Rokita, 2014 .

A prime/boost vaccine platform efficiently identifies CD27 agonism and depletion of myeloid-derived suppressor cells as therapies that rationally combine with checkpoint blockade in ovarian cancer

K. Odunsi, D. Kozbor, T. Keler, 2021, Cancer Immunology, Immunotherapy.

The GD2-specific 14G2a monoclonal antibody induces apoptosis and enhances cytotoxicity of chemotherapeutic drugs in IMR-32 human neuroblastoma cells.

H. Rokita, D. Kozbor, A. Kowalczyk, 2009, Cancer letters.

Tp44 molecules involved in antigen-independent T cell activation are expressed on human plasma cells.

L. Moretta, D. Kozbor, A. Moretta, 1987, Journal of immunology.

Enhanced human immunodeficiency virus infection in macrophages by high-molecular-weight dextran sulfate is associated with conformational changes of gp120 and expression of the CCR5 receptor.

P. Jagodziński, Y. Kaneko, D. Kozbor, 1999, Viral immunology.

Further studies of natural killer cell function in Chediak-Higashi patients.

J. White, J. Roder, D. Kozbor, 1982, Immunology.

Carboplatin enhances lymphocyte-endothelial interactions to promote CD8+ T cell trafficking into the ovarian tumor microenvironment.

Daniel T. Fisher, K. Odunsi, Minhyung Kim, 2022, Gynecologic oncology.

Cytokine patterns during progression to AIDS in children with perinatal HIV infection.

G. Trinchieri, D. Kozbor, M. Kubin, 1995, Journal of immunology.

A comparative analysis of the phenotypic characteristics of available fusion partners for the construction of human hybridomas.

J. Roder, D. Kozbor, D. Dexter, 1983, Hybridoma.

The EBV-hybridoma technique.

J. Roder, S. Cole, D. Kozbor, 1986, Methods in enzymology.

Selection of novel peptide mimics of the GD2 ganglioside from a constrained phage-displayed peptide library.

H. Rokita, D. Kozbor, A. Kowalczyk, 2007, International journal of molecular medicine.

Human monoclonal antibodies against Mycobacterium leprae

J. Roder, D. Kozbor, T. Atlaw, 1985, Infection and immunity.

The gene encoding the T4 antigen maps to human chromosome 12.

P. Nowell, D. Kozbor, J. Finan, 1986, Journal of immunology.

The Epstein—Barr Virus-Hybridoma Technique

J. Roder, R. Mcgarry, S. Cole, 1985 .

Human monoclonal antibodies

J. Roder, S. Cole, D. Kozbor, 1984, Molecular and Cellular Biochemistry.

Role of the V2, V3, and CD4-binding domains of GP120 in curdlan sulfate neutralization sensitivity of HIV-1 during infection of T lymphocytes.

P. Jagodziński, M. Gorny, A. Sieron, 1996, Virology.

Specific immunoglobulin production and enhanced tumorigenicity following ascites growth of human hybridomas.

J. Roder, S. Cole, D. Kozbor, 1985, Journal of immunological methods.

Protective role of beta-chemokines associated with HIV-specific Th responses against perinatal HIV transmission.

M. Polansky, S. Douglas, D. Kozbor, 1999, Journal of immunology.

Oncolytic Maraba virus armed with tumor antigen boosts vaccine priming and reveals diverse therapeutic response patterns when combined with checkpoint blockade in ovarian cancer

M. Seshadri, K. Odunsi, S. Battaglia, 2019, Journal of Immunotherapy for Cancer.

Modulation of the Tumor Microenvironment by CXCR4 Antagonist-Armed Viral Oncotherapy Enhances the Antitumor Efficacy of Dendritic Cell Vaccines against Neuroblastoma in Syngeneic Mice

Marcin Komorowski, D. Kozbor, R. Drożdż, 2018, Viruses.

DNA vaccine expressing the mimotope of GD2 ganglioside induces protective GD2 cross-reactive antibody responses.

A. Kolinski, P. Rotkiewicz, S. Ferrone, 2005, Cancer research.

Human hybridomas constructed with antigen-specific Epstein-Barr virus-transformed cell lines.

J. Roder, D. Kozbor, A. Lagarde, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Human anti-tetanus toxoid monoclonal antibody secreted by EBV-transformed human B cells fused with murine myeloma.

J. Roder, H. Koprowski, D. Kozbor, 1982, Hybridoma.

Establishment of Anti‐TNP Antibody‐producing Human Lymphoid Lines by Preselection for Hapten Binding followed by EBV Transformation

G. Klein, D. Kozbor, M. Steinitz, 1979, Scandinavian journal of immunology.

The Epstein-Barr Virus-Hybridoma Technique for Production of Human Monoclonal Antibodies

J. Roder, R. Burioni, D. Kozbor, 1988 .

CXCL12/CXCR4 Blockade by Oncolytic Virotherapy Inhibits Ovarian Cancer Growth by Decreasing Immunosuppression and Targeting Cancer-Initiating Cells

M. Seshadri, M. Opyrchal, K. Odunsi, 2014, The Journal of Immunology.

Induction of protective immune responses against NXS2 neuroblastoma challenge in mice by immunotherapy with GD2 mimotope vaccine and IL-15 and IL-21 gene delivery

E. Repasky, H. Rokita, M. Gil, 2007, Cancer Immunology, Immunotherapy.

Reprogramming the tumor microenvironment leverages CD8+ T cell responses to a shared tumor/self antigen in ovarian cancer

Jianmin Wang, A. Gambotto, K. Odunsi, 2023, Molecular therapy oncolytics.

The effect of epitope variation on the profile of cytotoxic T lymphocyte responses to the HIV envelope glycoprotein.

H. Teppler, Y. Kaneko, D. Kozbor, 1998, International immunology.

Reprogramming antitumor immunity against chemoresistant ovarian cancer by a CXCR4 antagonist-armed viral oncotherapy

M. Opyrchal, K. Odunsi, K. Eng, 2016, Molecular therapy oncolytics.

Association between HIV‐specific T helper responses and CTL activities in pediatric AIDS

G. Trinchieri, D. Kozbor, A. Wierzbicki, 2000, European journal of immunology.

Diminished HIV-specific CTL activity is associated with lower type 1 and enhanced type 2 responses to HIV-specific peptides during perinatal HIV infection.

P. Jagodziński, G. Trinchieri, D. Kozbor, 1997, Journal of immunology.

Human TCR-gamma+/delta+, CD8+ T lymphocytes recognize tetanus toxoid in an MHC-restricted fashion

M. Isobe, G. Russo, D. Monos, 1989, The Journal of experimental medicine.

Selective natural killer resistance in a clone of YAC lymphoma cells.

J. Roder, R. Kerbel, T. Beaumont, 1981, Proceedings of the National Academy of Sciences of the United States of America.

The effect of deletion of the V3 loop of gp120 on cytotoxic T cell responses and HIV gp120-mediated pathogenesis.

H. Teppler, K. Okumura, D. Kozbor, 1998, Journal of immunology.

The Effect of Deletion of the V 3 Loop of gp 120 on and Danuta Kozbor

H. Teppler, K. Okumura, D. Kozbor, 1998 .

A strategy for the production of human monoclonal antibodies reactive with lung tumor cell lines.

J. Roder, S. Cole, D. Kozbor, 1984, Cancer research.

Increased Level and Longevity of Protective Immune Responses Induced by DNA Vaccine Expressing the HIV-1 Env Glycoprotein when Combined with IL-21 and IL-15 Gene Delivery1

L. Stamatatos, P. Shrikant, D. Kozbor, 2006, The Journal of Immunology.

Cancer vaccine with mimotopes of tumor-associated carbohydrate antigens

D. Kozbor, 2010, Immunologic research.

Therapeutic effect of a T helper cell supported CTL response induced by a survivin peptide vaccine against murine cerebral glioma

T. Barone, D. Kozbor, M. Ciesielski, 2008, Cancer Immunology, Immunotherapy.

Evidence for B cell-mediated activation of V delta 1+ T lymphocytes during progression of HIV infection.

Y. Kaneko, D. Kozbor, E. Hyjek, 1997, Journal of immunology.

Effect of the V3 Loop Deletion of Envelope Glycoprotein on Cellular Responses and Protection against Challenge with Recombinant Vaccinia Virus Expressing gp160 of Primary Human Immunodeficiency Virus Type 1 Isolates

G. Trinchieri, A. Sieron, A. Srinivasan, 2002, Journal of Virology.

Oral DNA vaccination promotes mucosal and systemic immune responses to HIV envelope glycoprotein.

D. Kozbor, Y. Kaneko, I. Bednarek, 2000, Virology.

Photodynamic therapy augments the efficacy of oncolytic vaccinia virus against primary and metastatic tumours in mice

R. K. Pandey, M. Seshadri, M. Gil, 2011, British Journal of Cancer.

In vitro stimulated lymphocytes as a source of human hybridomas

J. Roder, D. Kozbor, 1984, European journal of immunology.

Induction of cell death in ovarian cancer cells by doxorubicin and oncolytic vaccinia virus is associated with CREB3L1 activation

Song Liu, K. Odunsi, H. Rokita, 2021, Molecular therapy oncolytics.

Clustered epitopes within the Gag-Pol fusion protein DNA vaccine enhance immune responses and protection against challenge with recombinant vaccinia viruses expressing HIV-1 Gag and Pol antigens.

A. Srinivasan, D. Kozbor, A. Wierzbicki, 2005, Virology.

Effect of partial and complete variable loop deletions of the human immunodeficiency virus type 1 envelope glycoprotein on the breadth of gp160-specific immune responses.

K. Komuro, D. Kozbor, Y. Kaneko, 2004, Virology.

Analysis of γδ+ T cells in peripheral blood of children with perinatal human immunodeficiency virus (HIV) infection

D. Kozbor, E. Hyjek, G. Kurzawski, 1993, Journal of Clinical Immunology.

Curdlan sulphate in human severe/cerebral Plasmodium falciparum malaria.

S. Krudsood, P. Thuma, D. Kozbor, 2005, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Enhancement of cellular and humoral immune responses to human immunodeficiency virus type 1 Gag and Pol by a G/P-92 fusion protein expressing highly immunogenic Gag p17/p24 and Pol p51 antigens.

D. Kozbor, Y. Kaneko, D. Kmieciak, 2001, Journal of human virology.

BiTE secretion by adoptively transferred stem-like T cells improves FRα+ ovarian cancer control

K. Odunsi, S. Rosario, M. Long, 2023, Journal for ImmunoTherapy of Cancer.

Modulation of the Tumor Microenvironment by CXCR4 Antagonist-Armed Viral Oncotherapy Enhances the Antitumor Efficacy of Dendritic Cell Vaccines against Neuroblastoma in Syngeneic Mice

Marcin Komorowski, D. Kozbor, R. Drożdż, 2018, Viruses.

A strategy for the production of human monoclonal antibodies reactive with lung tumor cell lines.

J. Roder, S. Cole, D. Kozbor, 1984, Cancer Research.

Expression and function of gamma delta- and alpha beta-T cell receptor heterodimers on human somatic T cell hybrids.

G. Trinchieri, D. Kozbor, M. Cassatella, 1990, Journal of immunology.