S. Cooper

发表

Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist

Christie M. Orschell, B. Graham-Evans, H. Broxmeyer, 2005, The Journal of experimental medicine.

Mouse hematopoietic cell-targeted STAT3 deletion: stem/progenitor cell defects, mitochondrial dysfunction, ROS overproduction, and a rapid aging-like phenotype.

Xin-Yuan Fu, H. Broxmeyer, C. Mantel, 2012, Blood.

Essential Role of Signal Transducer and Activator of Transcription (Stat)5a but Not Stat5b for Flt3-Dependent Signaling

W. Leonard, H. Broxmeyer, Younghee Lee, 2000, The Journal of experimental medicine.

Impaired Host Defense, Hematopoiesis, Granulomatous Inflammation and Type 1–Type 2 Cytokine Balance in Mice Lacking CC Chemokine Receptor 1

H. Broxmeyer, T. Wynn, H. Westphal, 1997, The Journal of experimental medicine.

Mast cell growth factor (c-kit ligand) supports the growth of human multipotential progenitor cells with a high replating potential.

D. Williams, H. Broxmeyer, G. Hangoc, 1991 .

Mast cell growth factor (c-kit ligand) supports the growth of human multipotential progenitor cells with a high replating potential.

D. Williams, H. Broxmeyer, G. Hangoc, 1991, Blood.

Myelosuppressive effects in vivo with very low dosages of monomeric recombinant murine macrophage inflammatory protein-1 alpha.

H. Broxmeyer, C. Mantel, S. Cooper, 1994, Experimental hematology.

DPP4 truncated GM-CSF and IL-3 manifest distinct receptor-binding and regulatory functions compared with their full-length forms

Boswell, H. Broxmeyer, C. Mantel, 2022 .

DPP4 Truncated GM-CSF & IL-3 Manifest Distinct Receptor Binding & Regulatory Functions Compared to their Full Length Forms

H. Broxmeyer, H. Boswell, C. Mantel, 2017, Leukemia.

Synergistic myelopoietic actions in vivo after administration to mice of combinations of purified natural murine colony-stimulating factor 1, recombinant murine interleukin 3, and recombinant murine granulocyte/macrophage colony-stimulating factor.

D. Williams, H. Broxmeyer, G. Hangoc, 1987, Proceedings of the National Academy of Sciences of the United States of America.

The influence in vivo of murine colony-stimulating factor-1 on myeloid progenitor cells in mice recovering from sublethal dosages of cyclophosphamide

D. Williams, H. Broxmeyer, A. Waheed, 1987 .

Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock

M. Ivan, N. Bardeesy, H. Broxmeyer, 2015, Cell.

Th1 cells regulate hematopoietic progenitor cell homeostasis by production of oncostatin M.

L. Naeger, M. Kaplan, T. Hoey, 2002, Immunity.

A novel chemokine, macrophage inflammatory protein-related protein-2, inhibits colony formation of bone marrow myeloid progenitors.

N. Copeland, D. Gilbert, N. Jenkins, 1995, Journal of immunology.

Involvement of Interleukin (IL) 8 receptor in negative regulation of myeloid progenitor cells in vivo: evidence from mice lacking the murine IL-8 receptor homologue

H. Broxmeyer, M. Moore, S. Cooper, 1996, The Journal of experimental medicine.

Isolation and characterization of Exodus-2, a novel C-C chemokine with a unique 37-amino acid carboxyl-terminal extension.

M. Klemsz, R. Hromas, H. Broxmeyer, 1997, Journal of immunology.

Characterization of CKbeta8 and CKbeta8-1: two alternatively spliced forms of human beta-chemokine, chemoattractants for neutrophils, monocytes, and lymphocytes, and potent agonists at CC chemokine receptor 1.

B. Kwon, H. Broxmeyer, M. Fraser, 1998, Blood.

Characterization of CKβ8 and CKβ8-1: Two Alternatively Spliced Forms of Human β-Chemokine, Chemoattractants for Neutrophils, Monocytes, and Lymphocytes, and Potent Agonists at CC Chemokine Receptor 1

B. Kwon, H. Broxmeyer, M. Fraser, 1998 .

TIP 110 / p 110 nrb / SART 3 / p 110 regulation of hematopoiesis through CMYC

Y. Liu, K. Timani, Yan Fan, 2011 .

COMPARATIVE ANALYSIS OF THE HUMAN MACROPHAGE INFLAMMATORY PROTEIN FAMILY OF CYTOKINES (CHEMOKINES) ON PROLIFERATION OF HUMAN MYELOID PROGENITOR CELLS

A. Cerami, H. Broxmeyer, P. Ralph, 1993 .

Comparative analysis of the human macrophage inflammatory protein family of cytokines (chemokines) on proliferation of human myeloid progenitor cells. Interacting effects involving suppression, synergistic suppression, and blocking of suppression.

A. Cerami, H. Broxmeyer, P. Ralph, 1993, Journal of immunology.

Low levels of erythroid and myeloid progenitors in thrombopoietin-and c-mpl-deficient mice.

H. Broxmeyer, F. D. de Sauvage, H. Broxmeyer, 1996, Blood.

TIP110/p110nrb/SART3/p110 regulation of hematopoiesis through CMYC.

Y. Liu, K. Timani, Yan Fan, 2011, Blood.

Human Hematopoietic Stem, Progenitor, and Immune Cells Respond Ex Vivo to SARS-CoV-2 Spike Protein

H. Broxmeyer, S. Cooper, Maegan L Capitano, 2020, Stem cell reviews and reports.

Multiple inhibitory cytokines induce deregulated progenitor growth and apoptosis in hematopoietic cells from Fac-/- mice.

M. Buchwald, H. Broxmeyer, D. Clapp, 1998, Blood.

Selective and indirect modulation of human multipotential and erythroid hematopoietic progenitor cell proliferation by recombinant human activin and inhibin.

A. Mason, H. Broxmeyer, L. Lu, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist.

B. Wood, H. Broxmeyer, G. Bridger, 2003, Blood.

Dipeptidylpeptidase 4 negatively regulates colony-stimulating factor activity and stress hematopoiesis

H. Broxmeyer, S. Farag, C. Mantel, 2012, Nature Medicine.

Angiopoietin-like-2 and -3 act through their coiled-coil domains to enhance survival and replating capacity of human cord blood hematopoietic progenitors.

H. Broxmeyer, G. Hangoc, S. Cooper, 2012, Blood cells, molecules & diseases.

Chemically-defined generation of human hemogenic endothelium and definitive hematopoietic progenitor cells.

S. Kuang, Xuepeng Wang, H. Broxmeyer, 2022, Biomaterials.

Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling.

D. Markovitz, N. Mor-Vaknin, H. Broxmeyer, 2019, The Journal of clinical investigation.

SDF-1α/CXCL12 enhances retroviral-mediated gene transfer into immature subsets of human and murine hematopoietic progenitor cells

H. Broxmeyer, H. Broxmeyer, G. Hangoc, 2004 .

CD166 Engagement Augments Mouse and Human Hematopoietic Progenitor Function via Activation of Stemness and Cell Cycle Pathways

H. Broxmeyer, S. Cooper, E. Srour, 2019, Stem cells.

Abrogating chemotherapy-induced myelosuppression by recombinant granulocyte-macrophage colony-stimulating factor in patients with sarcoma: protection at the progenitor cell level.

R. Frenck, W. Hittelman, H. Broxmeyer, 1992, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A positive effect of p21cip1/waf1 in the colony formation from murine myeloid progenitor cells as assessed by retroviral-mediated gene transfer.

R. Hromas, S. Braun, H. Broxmeyer, 1998, Blood cells, molecules & diseases.

The neurotransmitter receptor Gabbr1 regulates proliferation and function of hematopoietic stem and progenitor cells.

Katherine E. Zink, B. Cox, K. Pollok, 2019, Blood.

Myelopoietic enhancing effects of murine macrophage inflammatory proteins 1 and 2 on colony formation in vitro by murine and human bone marrow granulocyte/macrophage progenitor cells

A. Cerami, H. Broxmeyer, B. Sherry, 1989, The Journal of experimental medicine.

Ames hypopituitary dwarf mice demonstrate imbalanced myelopoiesis between bone marrow and spleen.

H. Broxmeyer, A. Bartke, S. Cooper, 2015, Blood cells, molecules & diseases.

AMD3100 and CD26 Modulate Mobilization, Engraftment, and Survival of Hematopoietic Stem and Progenitor Cells Mediated by the SDF‐1/CXCL12‐CXCR4 Axis

H. Broxmeyer, C. Mantel, S. Ito, 2007, Annals of the New York Academy of Sciences.

Enhanced myeloid progenitor cell cycling and apoptosis in mice lacking the chemokine receptor, CCR2.

A. Ritchie, H. Broxmeyer, I. Charo, 1999, Blood.

Stromal cell-derived factor-1/CXCL12 selectively counteracts inhibitory effects of myelosuppressive chemokines on hematopoietic progenitor cell proliferation in vitro.

H. Broxmeyer, G. Hangoc, S. Cooper, 2005, Stem cells and development.

Stromal cell‐derived factor‐1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and Gαi proteins and enhances engraftment of competitive, repopulating stem cells

H. Broxmeyer, C. Mantel, Younghee Lee, 2003, Journal of leukocyte biology.

Myeloid progenitor cell regulatory effects of vascular endothelial cell growth factor.

D. Donner, H. Broxmeyer, H. Y. Song, 1995, International journal of hematology.

Purified murine granulocyte/macrophage progenitor cells express a high-affinity receptor for recombinant murine granulocyte/macrophage colony-stimulating factor.

D. Williams, H. Broxmeyer, S. Cooper, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Altered responsiveness to chemokines due to targeted disruption of SHIP.

H. Broxmeyer, G. Krystal, C. Helgason, 1999, The Journal of clinical investigation.

Adipose stem cell treatment in mice attenuates lung and systemic injury induced by cigarette smoking.

H. Broxmeyer, I. Petrache, A. Fisher, 2011, American journal of respiratory and critical care medicine.

Cloning and Characterization of Exodus, a Novel β-Chemokine

M. Klemsz, R. Hromas, G. Bell, 1997 .

Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines.

A. Gotoh, H. Broxmeyer, C. Mantel, 2002, Blood.

Flt3 ligand stimulates/costimulates the growth of myeloid stem/progenitor cells.

H. Broxmeyer, L. Lu, S. Cooper, 1995, Experimental hematology.

The kit receptor and its ligand, steel factor, as regulators of hemopoiesis.

H. Broxmeyer, L. Lu, G. Hangoc, 1991, Cancer cells.

Synergistic effects of purified recombinant human and murine B cell growth factor-1/IL-4 on colony formation in vitro by hematopoietic progenitor cells. Multiple actions.

D. Williams, H. Broxmeyer, L. Lu, 1988, Journal of immunology.

A role for natural killer T cells and CD1d molecules in counteracting suppression of hematopoiesis in mice induced by infection with murine cytomegalovirus.

H. Broxmeyer, A. Dent, G. Hangoc, 2007, Experimental hematology.

Concise Review: Role of DEK in Stem/Progenitor Cell Biology

D. Markovitz, N. Mor-Vaknin, H. Broxmeyer, 2013, Stem cells.

Cloning and characterization of exodus, a novel beta-chemokine.

M. Klemsz, R. Hromas, G. Bell, 1997, Blood.

CD1d expression on and regulation of murine hematopoietic stem and progenitor cells.

H. Broxmeyer, C. Mantel, G. Hangoc, 2012, Blood.

T-cell growth factor P40 promotes the proliferation of myeloid cell lines and enhances erythroid burst formation by normal murine bone marrow cells in vitro.

D. Williams, P. Morrissey, H. Broxmeyer, 1990, Blood.

Distinct requirements for Stat4 and Stat6 in hematopoietic progenitor cell responses to growth factors and chemokines.

M. Kaplan, H. Broxmeyer, Younghee Lee, 2003, Journal of hematotherapy & stem cell research.

Dominant Myelopoietic Effector Functions Mediated by Chemokine Receptor CCR1

H. Broxmeyer, G. Hangoc, S. Cooper, 1999, The Journal of experimental medicine.

The opposing actions in vivo on murine myelopoiesis of purified preparations of lactoferrin and the colony stimulating factors.

D. Williams, P. Ralph, H. Broxmeyer, 1987, Blood cells.

Hematopoietic colony formation from human growth factor-dependent TF1 cells and human cord blood myeloid progenitor cells depends on SHP2 phosphatase function.

A. Gotoh, S. Braun, H. Broxmeyer, 2013, Stem cells and development.

Adeno-associated virus 2-mediated gene transfer in murine hematopoietic progenitor cells.

H. Broxmeyer, A. Srivastava, A. Srivastava, 1993, Experimental hematology.

Macrophage Inflammatory Protein-1α and Interferon-Inducible Protein 10 Inhibit Synergistically Induced Growth Factor Stimulation of MAP Kinase Activity and Suppress Phosphorylation of Eukaryotic Initiation Factor 4E and 4E Binding Protein 1

A. Gingras, N. Sonenberg, H. Broxmeyer, 1997 .

Cell surface peptidase CD26/DPPIV mediates G-CSF mobilization of mouse progenitor cells.

H. Broxmeyer, S. Cooper, K. Christopherson, 2003, Blood.

Human gamma interferon enhances release from phytohemagglutinin-stimulated T4+ lymphocytes of activities that stimulate colony formation by granulocyte-macrophage, erythroid, and multipotential progenitor cells.

D. Williams, H. Broxmeyer, W. Piacibello, 1986, Blood.

Effects of Eupalinilide E and UM171, alone and in combination on cytokine stimulated ex-vivo expansion of human cord blood hematopoietic stem cells.

D. Siegel, H. Broxmeyer, S. Cooper, 2020, Blood cells, molecules & diseases.

Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment

H. Broxmeyer, S. Cooper, Xinxin Huang, 2017, Nature Medicine.

TGF-beta combined with M-CSF and IL-4 induces generation of immune inhibitory cord blood dendritic cells capable of enhancing cytokine-induced ex vivo expansion of myeloid progenitors.

B. Graham-Evans, H. Broxmeyer, Young‐June Kim, 2007, Blood.

Cord blood stem and progenitor cells.

Christie M. Orschell, H. Broxmeyer, M. Yoder, 2006, Methods in enzymology.

Chromatin remodeling subunit BRM and valine regulate hematopoietic stem/progenitor cell function and self-renewal via intrinsic and extrinsic effects

H. Broxmeyer, S. Cooper, Xinxin Huang, 2021, Leukemia.

Modulation of Hematopoietic Chemokine Effects In Vitro and In Vivo by DPP-4/CD26.

H. Broxmeyer, G. Hangoc, S. Cooper, 2016, Stem cells and development.

Mitigating oxygen stress enhances aged mouse hematopoietic stem cell numbers and function.

Christie M. Orschell, H. Broxmeyer, S. Cooper, 2021, The Journal of clinical investigation.

Human interferon-inducible protein 10: expression and purification of recombinant protein demonstrate inhibition of early human hematopoietic progenitors

J. Krueger, H. Broxmeyer, A. Sarris, 1993, The Journal of experimental medicine.

The IL-17 cytokine family members are inhibitors of human hematopoietic progenitor proliferation.

R. Hromas, E. Williamson, H. Broxmeyer, 2006, Blood.

Enhancing and suppressing effects of recombinant murine macrophage inflammatory proteins on colony formation in vitro by bone marrow myeloid progenitor cells.

A. Cerami, H. Broxmeyer, B. Sherry, 1990, Blood.

Collection and Processing of Mobilized Mouse Peripheral Blood at Lowered Oxygen Tension Yields Enhanced Numbers of Hematopoietic Stem Cells

H. Broxmeyer, S. Cooper, Arafat Aljoufi, 2020, Stem Cell Reviews and Reports.

High Activity Suppression of Myeloid Progenitor Proliferation by Chimeric Mutants of Interleukin 8 and Platelet Factor 4 (*)

H. Broxmeyer, S. Cooper, G. Larosa, 1995, The Journal of Biological Chemistry.

Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21- to 23.5-year cryopreserved cord blood.

S. Witting, K. Cornetta, H. Broxmeyer, 2011, Blood.

cryopreserved cord blood stem cells, and isolation of endothelial progenitors from 21- to 23.5-year Hematopoietic stem/progenitor cells, generation of induced pluripotent

S. Witting, K. Cornetta, H. Broxmeyer, 2011 .

Cyclin dependent kinase inhibitors differentially modulate synergistic cytokine responsiveness of hematopoietic progenitor cells.

D. Franklin, H. Broxmeyer, C. Mantel, 2012, Stem cells and development.

Enhanced collection of phenotypic and engrafting human cord blood hematopoietic stem cells at 4°C

H. Broxmeyer, S. Cooper, Maegan L Capitano, 2020, Stem cells.

Macrophage-stimulating protein, a ligand for the RON receptor protein tyrosine kinase, suppresses myeloid progenitor cell proliferation and synergizes with vascular endothelial cell growth factor and members of the chemokine family

D. Donner, E. Leonard, A. Sarris, 1996, Annals of Hematology.

The IL-33 Receptor/ST2 acts as a positive regulator of functional mouse bone marrow hematopoietic stem and progenitor cells

H. Broxmeyer, S. Paczesny, S. Cooper, 2020, Blood cells, molecules & diseases.

Leukocytosis and Mobilization of CD34+ Hematopoietic Progenitor Cells by AMD3100, a CXCR4 Antagonist.

B. Wood, H. Broxmeyer, G. Bridger, 2004, Supportive cancer therapy.

Involvement o f lnterleukin ( IL ) 8 Receptor in Negative Regulat ion o f Myeloid Progenitor Cells In Vivo : Evidence from Mice Lacking the Murine IL-8 Receptor H o m o l o g u e By

H. Broxmeyer, M. Moore, S. Cooper, 2022 .

Measurement of Interleukin 3 and Other Hematopoietic Cytokines, such as GM‐CSF, G‐CSF, M‐CSF, Erythropoietin, Steel Factor, and Flt‐3 Ligand

H. Broxmeyer, S. Cooper, 2000, Current protocols in immunology.

Nonmarrow hematopoiesis occurs in a hyaluronic-acid-rich node and duct system in mice.

H. Broxmeyer, G. Hangoc, S. Cooper, 2014, Stem cells and development.

Mild Heat Treatment Primes Human CD34+ Cord Blood Cells for Migration Toward SDF‐1α and Enhances Engraftment in an NSG Mouse Model

H. Broxmeyer, G. Hangoc, S. Cooper, 2015, Stem cells.

SDF-1/CXCL12 enhances in vitro replating capacity of murine and human multipotential and macrophage progenitor cells.

M. Dinauer, H. Broxmeyer, G. Hangoc, 2007, Stem cells and development.

Myelopoiesis In Vivo to Growth Factor Withdrawal and Enhances Survival/Antiapoptosis In Vitro in Response Ligand 12 Enhances Myeloid Progenitor Cell Cell-Derived Factor-1/CXC Chemokine Transgenic Expression of Stromal

H. Broxmeyer, C. Mantel, Younghee Lee, 2002 .

T-cell growth factor P40 promotes the proliferation of myeloid cell lines and enhances erythroid burst formation by normal murine bone marrow cells in vitro

David A. Williams, Diana Anderson, P. Morrissey, 1990 .

Inhibit Synergistically Induced Growth Factor Stimulation of MAP Kinase Activity and Suppress Phosphorylation of Eukaryotic Initiation Factor 4E and 4E Binding Protein 1

A. Gingras, N. Sonenberg, H. Broxmeyer, 1997 .

Estrogen loss upregulates hematopoiesis in the mouse: a mediating role of IL-6.

H. Broxmeyer, J. Abrams, G. Passeri, 1995, Experimental hematology.

Cloning and Characterization of Exodus , a Novel b-Chemokine

M. Klemsz, R. Hromas, G. Bell, 1997 .

Macrophage inflammatory protein-1 alpha enhances growth factor-stimulated phosphatidylcholine metabolism and increases cAMP levels in the human growth factor-dependent cell line M07e, events associated with growth suppression.

M. Marshall, C. Mantel, H. Broxmeyer, 1995, Journal of immunology.

Identification of a massive reserve of hematopoietic progenitors in mice.

H. Broxmeyer, L. Lasky, F. D. de Sauvage, 2005, Stem cells and development.

Phosphatidylinositol transfer proteins regulate megakaryocyte TGF-β1 secretion and hematopoiesis in mice.

M. Marks, H. Broxmeyer, A. Dent, 2018, Blood.

Effects of hematopoietic suppressor molecules on the in vitro proliferation of purified murine granulocyte-macrophage progenitor cells.

D. Williams, H. Broxmeyer, S. Cooper, 1988, Cancer research.

Polymerization of murine macrophage inflammatory protein 1 alpha inactivates its myelosuppressive effects in vitro: the active form is a monomer.

H. Broxmeyer, C. Mantel, S. Cooper, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Lymphocytes, and Potent Agonists at CC Chemokine Receptor 1 -Chemokine, Chemoattractants for Neutrophils, Monocytes, and β Human 8-1: Two Alternatively Spliced Forms of β 8 and CK β Characterization of CK

B. Kwon, H. Broxmeyer, M. Fraser, 2013 .

The influence of purified recombinant human heavy-subunit and light-subunit ferritins on colony formation in vitro by granulocyte-macrophage and erythroid progenitor cells.

D. Williams, H. Broxmeyer, H. Broxmeyer, 1986, Blood.

Effect of murine mast cell growth factor (c-kit proto-oncogene ligand) on colony formation by human marrow hematopoietic progenitor cells.

D. Williams, H. Broxmeyer, L. Lu, 1991, Blood.

Influence of murine mast cell growth factor (c-kit ligand) on colony formation by mouse marrow hematopoietic progenitor cells.

D. Williams, H. Broxmeyer, G. Hangoc, 1991, Experimental hematology.

Comparative effects in vivo of recombinant murine interleukin 3, natural murine colony-stimulating factor-1, and recombinant murine granulocyte-macrophage colony-stimulating factor on myelopoiesis in mice.

D. Williams, H. Broxmeyer, A. Waheed, 1987, The Journal of clinical investigation.

The suppressive influences of human tumor necrosis factors on bone marrow hematopoietic progenitor cells from normal donors and patients with leukemia: synergism of tumor necrosis factor and interferon-gamma.

D. Williams, R. Hoffman, H. Broxmeyer, 1986, Journal of immunology.

High-efficiency recovery of functional hematopoietic progenitor and stem cells from human cord blood cryopreserved for 15 years

D. Bodine, H. Broxmeyer, S. Anderson, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Activation of OCT4 enhances ex vivo expansion of human cord blood hematopoietic stem and progenitor cells by regulating HOXB4 expression

H. Broxmeyer, G. Hangoc, S. Cooper, 2015, Leukemia.

Profiling of differentially expressed apoptosis-related genes by cDNA arrays in human cord blood CD34+ cells treated with etoposide.

H. Broxmeyer, G. Hangoc, S. Cooper, 2003, Experimental hematology.

Hematopoietic defects in mice lacking the sialomucin CD34.

H. Broxmeyer, L. Lasky, H. Broxmeyer, 1996, Blood.

Mutated recombinant human heavy-chain ferritins and myelosuppression in vitro and in vivo: a link between ferritin ferroxidase activity and biological function.

H. Broxmeyer, S. Cooper, P. Arosio, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Comparative Proteomic Analysis of Human CD34+ Stem/Progenitor Cells and Mature CD15+ Myeloid Cells

Mu Wang, H. Broxmeyer, S. Cooper, 2004, Stem cells.

Fanconi anemia type C and p53 cooperate in apoptosis and tumorigenesis.

H. Broxmeyer, D. Clapp, S. Cooper, 2003, Blood.

Adeno-associated virus 2-mediated high efficiency gene transfer into immature and mature subsets of hematopoietic progenitor cells in human umbilical cord blood

S. Heimfeld, H. Broxmeyer, A. Srivastava, 1994, The Journal of experimental medicine.

SIRT1 deficiency compromises mouse embryonic stem cell differentiation, and embryonic and adult hematopoiesis in the mouse

C. Deng, H. Broxmeyer, H. Chae, 2012 .

Human recombinant interferon-inducible protein-10: intact disulfide bridges are not required for inhibition of hematopoietic progenitors and chemotaxis of T lymphocytes and monocytes.

D. Taub, H. Broxmeyer, A. Sarris, 2001, Journal of hematotherapy & stem cell research.

Leptin receptor, a surface marker for a subset of highly engrafting long-term functional hematopoietic stem cells

H. Broxmeyer, S. Cooper, E. Srour, 2020, Leukemia.

Enhanced Green Fluorescent Protein Is a Nearly Ideal Long‐Term Expression Tracer for Hematopoietic Stem Cells, Whereas DsRed‐Express Fluorescent Protein Is Not

K. Cornetta, H. Broxmeyer, G. Hangoc, 2007, Stem cells.

The effects of purified recombinant murine interleukin-3 and/or purified natural murine CSF-1 in vivo on the proliferation of murine high- and low-proliferative potential colony-forming cells: demonstration of in vivo synergism.

D. Williams, H. Broxmeyer, A. Waheed, 1987, Blood.

Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis.

E. Richfield, D. Stumpo, P. Blackshear, 2008, Blood.

Suppressive effects in vivo of purified recombinant human H-subunit (acidic) ferritin on murine myelopoiesis.

D. Williams, H. Broxmeyer, G. Hangoc, 1989, Blood.

and in vivo by IL-20 Selective enhancement of multipotential hematopoietic progenitors in vitro

Dan Liu, D. Witcher, V. Wroblewski, 2013 .

Selective enhancement of multipotential hematopoietic progenitors in vitro and in vivo by IL-20.

H. Broxmeyer, D. Witcher, V. Wroblewski, 2003, Blood.

Synergistic inhibition in vivo of bone marrow myeloid progenitors by myelosuppressive chemokines and chemokine-accelerated recovery of progenitors after treatment of mice with Ara-C.

R. Hromas, H. Broxmeyer, G. Hangoc, 2006, Experimental hematology.

Effects of CC, CXC, C, and CX3C Chemokines on Proliferation of Myeloid Progenitor Cells, and Insights into SDF‐1‐Induced Chemotaxis of Progenitors a

R. Hromas, H. Broxmeyer, G. Hangoc, 1999, Annals of the New York Academy of Sciences.

Functional activities of acidic isoferritins and lactoferrin in vitro and in vivo.

L. Juliano, W. Piacibello, H. Broxmeyer, 1984, Blood cells.

Class II transactivator-mediated regulation of major histocompatibility complex class II antigen expression is important for hematopoietic progenitor cell suppression by chemokines and iron-binding proteins.

H. Broxmeyer, G. Hangoc, S. Cooper, 2006, Experimental hematology.

In vivo effects of recombinant interleukin-11 on myelopoiesis in mice.

H. Broxmeyer, G. Hangoc, S. Cooper, 1993, Blood.

Regulation of myeloid progenitor cell proliferation/survival by IL-31 receptor and IL-31.

B. Graham-Evans, H. Broxmeyer, F. D. de Sauvage, 2007, Experimental hematology.

Transgenic Expression of Stromal Cell-Derived Factor-1/CXC Chemokine Ligand 12 Enhances Myeloid Progenitor Cell Survival/Antiapoptosis In Vitro in Response to Growth Factor Withdrawal and Enhances Myelopoiesis In Vivo

H. Broxmeyer, C. Mantel, Younghee Lee, 2003, The Journal of Immunology.

Altered Hematopoiesis, Behavior, and Sexual Function in μ Opioid Receptor–deficient Mice

H. Jansen, M. Lehman, J. Tischfield, 1997, The Journal of experimental medicine.

CD45 cell surface antigens are linked to stimulation of early human myeloid progenitor cells by interleukin 3 (IL-3), granulocyte/macrophage colony-stimulating factor (GM-CSF), a GM-CSF/IL- 3 fusion protein, and mast cell growth factor (a c-kit ligand)

D. Williams, H. Broxmeyer, J. Ledbetter, 1991, The Journal of experimental medicine.

Enhanced stimulation of human bone marrow macrophage colony formation in vitro by recombinant human macrophage colony-stimulating factor in agarose medium and at low oxygen tension.

C. Langefeld, H. Broxmeyer, P. Ralph, 1990, Blood.

Multiple Inhibitory Cytokines Induce Deregulated Progenitor Growth and Apoptosis in Hematopoietic Cells from Fac -/- Mice • 765

H. Broxmeyer, D. Clapp, G. Hangoc, 1998, Pediatric Research.

Qualitative functional deficiency of affinity-purified lactoferrin from neutrophils of patients with chronic myelogenous leukemia, and lactoferrin/H-ferritin-cell interactions in a patient with lactoferrin-deficiency with normal numbers of circulating leukocytes.

D. Williams, H. Broxmeyer, T. Coates, 1991, Pathobiology : journal of immunopathology, molecular and cellular biology.

AMD 3100 and CD 26 Modulate Mobilization , Engraftment , and Survival of Hematopoietic Stem and Progenitor Cells Mediated by the SDF-1 / CXCL 12-CXCR 4 Axis

H. Broxmeyer, C. Mantel, S. Ito, 2007 .

Mad2 is required for optimal hematopoiesis: Mad2 associates with c-Kit in MO7e cells.

H. Broxmeyer, C. Mantel, S. Ito, 2007, Blood.

Pak2 Regulates Hematopoietic Progenitor Cell Proliferation, Survival, and Differentiation

G. Sandusky, H. Broxmeyer, J. Chernoff, 2015, Stem cells.

The effects in vivo of purified preparations of murine macrophage colony stimulating factor-1, recombinant murine granulocyte-macrophage colony stimulating factor and natural and recombinant murine interleukin 3 without and with pretreatment of mice with purified iron-saturated human lactoferrin.

D. Williams, A. Waheed, H. Boswell, 1986, Immunobiology.

Abnormal Chemokine-Induced Responses of Immature and Mature Hematopoietic Cells from Motheaten Mice Implicate the Protein Tyrosine Phosphatase Shp-1 in Chemokine Responses

H. Broxmeyer, G. Feng, G. Hangoc, 1999, The Journal of experimental medicine.

Chemokine Regulation of Hematopoiesis and the Involvement of Pertussis Toxin‐Sensitive Gαi Proteins

H. Broxmeyer, C. Mantel, G. Hangoc, 2001, Annals of the New York Academy of Sciences.

Human Hematopoietic Stem, Progenitor, and Immune Cells Respond Ex Vivo to SARS-CoV-2 Spike Protein

H. Broxmeyer, S. Cooper, James P. Ropa, 2020, Stem Cell Reviews and Reports.

SIRT1 deficiency compromises mouse embryonic stem cell hematopoietic differentiation, and embryonic and adult hematopoiesis in the mouse.

C. Deng, H. Broxmeyer, H. Chae, 2011, Blood.

Clonogenic methods in vitro for the enumeration of granulocyte-macrophage progenitor cells (CFU-GM) in human bone marrow and mouse bone marrow and spleen

H. Broxmeyer, S. Cooper, 1991 .

The Effects of Oxidizing Species Derived from Molecular Oxygen on the Proliferation In Vitro of Human Granulocyte‐Macrophage Progenitor Cells a

H. Broxmeyer, S. Cooper, Theodore Gabic, 1989, Annals of the New York Academy of Sciences.

Influence of purified recombinant human macrophage colony stimulating factor in mice.

D. Williams, H. Broxmeyer, S. Cooper, 1989, Biotechnology therapeutics.

Interactions between purified murine colony-stimulating factors (natural CSF-1, recombinant GM-CSF, and recombinant IL-3) on the in vitro proliferation of purified murine granulocyte-macrophage progenitor cells.

D. Williams, H. Broxmeyer, A. Waheed, 1987, Experimental hematology.

The influence in vivo of murine colony-stimulating factor-1 on myeloid progenitor cells in mice recovering from sublethal dosages of cyclophosphamide.

D. Williams, A. Waheed, H. Broxmeyer, 1987, Blood.

Adeno-associated Virus 2-mediated High Et ~ ciency Gene Transfer into Irm , nature and Mature Subsets of Hematopoietic Progenitor Cells in Human Umbilical Cord Blood

S. Heimfeld, H. Broxmeyer, S. Cooper, 2003 .

A phase III, randomized, multicenter, open-label study of venetoclax or pomalidomide in combination with dexamethasone in patients with t(11;14)-positive relapsed/refractory multiple myeloma.

M. Dimopoulos, Shaji K. Kumar, E. Arriola, 2020 .

Macrophage inflammatory protein (MIP)-1 beta abrogates the capacity of MIP-1 alpha to suppress myeloid progenitor cell growth.

D. Williams, A. Cerami, H. Broxmeyer, 1991, Journal of immunology.

The synergistic influence of human interferon-gamma and interferon-alpha on suppression of hematopoietic progenitor cells is additive with the enhanced sensitivity of these cells to inhibition by interferons at low oxygen tension in vitro.

H. Broxmeyer, S. Cooper, B. Rubin, 1985, Journal of immunology.

Interferon-inducible Protein 10 and Macrophage Inflammatory Protein-1α Inhibit Growth Factor Stimulation of Raf-1 Kinase Activity and Protein Synthesis in a Human Growth Factor-dependent Hematopoietic Cell Line (*)

H. Broxmeyer, M. Marshall, A. Sarris, 1995, The Journal of Biological Chemistry.

The chemokine CCL21 protects normal marrow progenitors from Ara-C cytotoxicity

R. Hromas, H. Broxmeyer, S. Cooper, 2002, Cancer Chemotherapy and Pharmacology.

Effects of in vivo treatment with PIXY321 (GM-CSF/IL-3 fusion protein) on proliferation kinetics of bone marrow and blood myeloid progenitor cells in patients with sarcoma.

R. Benjamin, H. Broxmeyer, S. Cooper, 1995, Experimental hematology.

DEK regulates hematopoietic stem engraftment and progenitor cell proliferation.

D. Markovitz, H. Broxmeyer, G. Hangoc, 2012, Stem cells and development.

Numbers of long-term hematopoietic stem cells from bone marrow of fanca and fancc knockout mice can be greatly enhanced by their collection and processing in physioxia conditions.

H. Broxmeyer, D. Clapp, S. Cooper, 2020, Blood Cells, Molecules & Diseases.

Combinations of antioxidants and/or of epigenetic enzyme inhibitors allow for enhanced collection of mouse bone marrow hematopoietic stem cells in ambient air.

H. Broxmeyer, S. Cooper, Xinxin Huang, 2018, Blood cells, molecules & diseases.

The exodus subfamily of CC chemokines inhibits the proliferation of chronic myelogenous leukemia progenitors.

R. Hromas, H. Broxmeyer, L. Cripe, 2000, Blood.

STAT3-dependent IL-21 production from T helper cells regulates hematopoietic progenitor cell homeostasis.

D. Levy, M. Kaplan, H. Broxmeyer, 2011, Blood.

The Brain: Is it a Next Frontier to Better Understand the Regulation and Control of Hematopoiesis for Future Modulation and Treatment?

Karmen K. Yoder, G. Hutchins, Yu-chien Wu, 2021, Stem Cell Reviews and Reports.

Nuclear translocation of TFE3 under hypoxia enhances the engraftment of human hematopoietic stem cells

Xuepeng Wang, H. Broxmeyer, S. Cooper, 2022, Leukemia.

(acidic) ferritin on murine myelopoiesis Suppressive effects in vivo of purified recombinant human H-subunit

H. Broxmeyer, G. Hangoc, S. Cooper, 2011 .

Suppressive effects in vivo of purified recombinant human H-subunit (acidic) ferritin on murine myelopoiesis

David A. Williams, H. Broxmeyer, G. Hangoc, 1989 .

The influence in vivo of natural murine interleukin-3 on the proliferation of myeloid progenitor cells in mice recovering from sublethal dosages of cyclophosphamide.

D. Williams, H. Broxmeyer, S. Cooper, 1987, Leukemia research.

Activities derived from established human myeloid cell lines reverse the suppression of cell line colony formation by lactoferrin and transferrin.

L. Juliano, J. Singer, H. Broxmeyer, 1986, Experimental hematology.

and erythroid progenitor cells subunit ferritins on colony formation in vitro by granulocyte- macrophage The influence of purified recombinant human heavy-subunit and light-

H. Broxmeyer, S. Cooper, P. Arosio, 2011 .

Chemokine regulation of hematopoiesis and the involvement of pertussis toxin-sensitive G alpha i proteins.

H. Broxmeyer, C. Mantel, G. Hangoc, 2001, Annals of the New York Academy of Sciences.

Effect in vivo of multiple injections of purified murine and recombinant human macrophage colony-stimulating factor to mice.

D. Williams, H. Broxmeyer, A. Waheed, 1989, Cancer research.

Mad 2 is required for optimal hematopoiesis : Mad 2 associates with c-Kit in MO 7 e cells

H. Broxmeyer, C. Mantel, S. Ito, 2006 .

Umbilical cord blood hematopoietic stem and repopulating cells in human clinical transplantation.

J. Kurtzberg, J. Falkenburg, H. Broxmeyer, 1991, Blood cells.

Growth characteristics of marrow hematopoietic progenitor/precursor cells from patients on a phase I clinical trial with purified recombinant human granulocyte-macrophage colony-stimulating factor.

D. Williams, J. Gutterman, H. Broxmeyer, 1988, Experimental hematology.

Phosphatidylinositol transfer proteins regulate megakaryocyte TGF-β1 secretion and hematopoiesis in mice.

M. Marks, H. Broxmeyer, A. Dent, 2018, Blood.

Physioxia-induced downregulation of Tet2 in hematopoietic stem cells contributes to enhanced self-renewal

H. Broxmeyer, S. Cooper, Baskar Ramdas, 2022, Blood.

Angiopoietin-like-2 and -3 act through their coiled-coil domains to enhance survival and replating capacity of human cord blood hematopoietic progenitors.

H. Broxmeyer, G. Hangoc, S. Cooper, 2012, Blood cells, molecules & diseases.

DEK Regulates Hematopoietic Stem Engraftment and Progenitor Cell Proliferation

D. Markovitz, H. Broxmeyer, G. Hangoc, 2011 .

Fanconi anemia type C and p53 cooperate in apoptosis and tumorigenesis.

H. Broxmeyer, S. Cooper, Xiaxin Li, 2003, Blood.

in MO7e cells Mad2 is required for optimal hematopoiesis: Mad2 associates with c-Kit

C. Mantel, S. Ito, S. Cooper, 2013 .

Mad 2 is required for optimal hematopoiesis : Mad 2 associates with c-Kit in MO 7 e cells

H. Broxmeyer, C. Mantel, S. Ito, 2007 .

Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21- to 23.5-year cryopreserved cord blood.

S. Witting, K. Cornetta, H. Broxmeyer, 2011, Blood.