J. Swartz

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Engineered clostridial [FeFe]-hydrogenase shows improved O2 tolerance in Chlamydomonas reinhardtii

Noam Shahar, I. Yacoby, Tamar Elman, 2020 .

Toward a genome scale sequence specific dynamic model of cell-free protein synthesis in Escherichia coli

J. Varner, J. Wayman, J. Swartz, 2019, Metabolic engineering communications.

Toward a genome scale sequence specific dynamic model of cell-free protein synthesis in Escherichia coli

J. Varner, J. Wayman, J. Swartz, 2017, bioRxiv.

Atypical Combinations and Scientific Impact

W. Myers, R. D. Britt, J. Swartz, 2013 .

Development of an In Vitro Compartmentalization Screen for High-Throughput Directed Evolution of [FeFe] Hydrogenases

James A. Stapleton, James R. Swartz, J. Stapleton, 2010, PloS one.

Sequence Specific Modeling of E. coli Cell-Free Protein Synthesis

J. Varner, J. Wayman, J. Swartz, 2017, bioRxiv.

Prolonging cell-free protein synthesis with a novel ATP regeneration system.

Dong-Myung Kim, J. Swartz, D. M. Kim, 1999, Biotechnology and bioengineering.

Substrate replenishment extends protein synthesis with an in vitro translation system designed to mimic the cytoplasm

M. Jewett, J. Swartz, James R. Swartz, 2004, Biotechnology and bioengineering.

Streamlined circular proximity ligation assay provides high stringency and compatibility with low-affinity antibodies

Ronald W. Davis, Henrik H. J. Persson, J. Horecka, 2018, Proceedings of the National Academy of Sciences.

Multiply mutated Gaussia luciferases provide prolonged and intense bioluminescence.

Karthish Manthiram, Kedar G. Patel, J. Swartz, 2009, Biochemical and biophysical research communications.

Continued Protein Synthesis at Low [ATP] and [GTP] Enables Cell Adaptation during Energy Limitation

Michael C. Jewett, James R. Swartz, M. Jewett, 2008, Journal of bacteriology.

Overexpression of Escherichia coli oxidoreductases increases recombinant insulin-like growth factor-I accumulation.

J. Joly, J. Swartz, W. S. Leung, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Construction of expression vectors for secretion of human interferons by yeast.

L. J. Perry, W. Kohr, C. Y. Chen, 1986, Methods in enzymology.

Protein folding activities of Escherichia coli protein disulfide isomerase.

J. Joly, J. Swartz, John C. Joly, 1994, Biochemistry.

Effect of Sequences of the Active-Site Dipeptides of DsbA and DsbC on In Vivo Folding of Multidisulfide Proteins inEscherichia coli

Paul H. Bessette, J. Bardwell, J. Swartz, 2001, Journal of bacteriology.

Cell-free biomanufacturing

Bradley C. Bundy, G. Rao, D. Wood, 2018, Current Opinion in Chemical Engineering.

High-Density, Defined Media Culture for the Production ofEscherichia coliCell Extracts

J. Swartz, J. Zawada, B. Richter, 2003 .

Rapid expression of functional genomic libraries.

K. Woodrow, J. Swartz, Isoken O Airen, 2006, Journal of proteome research.

Universal cell-free protein synthesis

J. Swartz, 2009, Nature Biotechnology.

Using E. coli-based cell-free protein synthesis to evaluate the kinetic performance of an orthogonal tRNA and aminoacyl-tRNA synthetase pair.

Cem Albayrak, J. Swartz, 2013, Biochemical and biophysical research communications.

Generation of hydrogen from NADPH using an [FeFe] hydrogenase

James R. Swartz, J. Swartz, Phillip R. Smith, 2012 .

Opportunities toward hydrogen production biotechnologies.

J. Swartz, 2020, Current opinion in biotechnology.

High-Throughput Screening of Catalytic H2 Production.

Sylvie Liong, J. Swartz, Ja-Hyup Koo, 2017, Angewandte Chemie.

Efficient , Highly Productive Hydrogen Production from Glucose Annual Report 5 / 1 / 12 to 4 / 30 / 13

Sylvie Liong, J. Swartz, Franklin Lu, 2013 .

Cell‐free production of active E. coli thioredoxin reductase and glutathione reductase

J. Swartz, Kurtis G. Knapp, 2004, FEBS letters.

Assessing sequence plasticity of a virus-like nanoparticle by evolution toward a versatile scaffold for vaccines and drug delivery

Wei Chan, Christopher C. VanLang, J. Swartz, 2015, Proceedings of the National Academy of Sciences.

In vitro and in vivo redox states of the Escherichia coli periplasmic oxidoreductases DsbA and DsbC.

J. Joly, J. Swartz, 1997, Biochemistry.

Biosynthesis of the [FeFe] Hydrogenase H Cluster: A Central Role for the Radical SAM Enzyme HydG.

R. D. Britt, J. Swartz, Jon M. Kuchenreuther, 2016, Inorganic chemistry.

The HydG Enzyme Generates an Fe(CO)2(CN) Synthon in Assembly of the FeFe Hydrogenase H-Cluster

W. Myers, R. D. Britt, J. Swartz, 2014, Science.

Localization of BiP to translating ribosomes increases soluble accumulation of secreted eukaryotic proteins in an E. coli cell-free system

J. Swartz, J. Bonomo, J. Welsh, 2011 .

Efficient and scalable method for scaling up cell free protein synthesis in batch mode.

J. Swartz, A. Voloshin, 2005, Biotechnology and bioengineering.

Nuclear resonance vibrational spectroscopy and electron paramagnetic resonance spectroscopy of 57Fe-enriched [FeFe] hydrogenase indicate stepwise assembly of the H-cluster.

W. Myers, R. D. Britt, J. Swartz, 2013, Biochemistry.

E. coli-based in vitro transcription/translation: in vivo-specific synthesis rates and high yields in a batch system.

R. Patnaik, J. Swartz, 1998, BioTechniques.

Cell-free technologies for biopharmaceutical research and production.

J. Swartz, R. Kiss, T. Hallam, 2022, Current opinion in biotechnology.

X-ray crystallographic and EPR spectroscopic analysis of HydG, a maturase in [FeFe]-hydrogenase H-cluster assembly

J. Essex, P. Roach, R. D. Britt, 2015, Proceedings of the National Academy of Sciences.

A filter microplate assay for quantitative analysis of DNA binding proteins using fluorescent DNA.

J. Swartz, William C. Yang, 2011, Analytical biochemistry.

Cell-free synthesis of the H-cluster: a model for the in vitro assembly of metalloprotein metal centers.

J. Swartz, Jon M. Kuchenreuther, Stacey A. Shiigi, 2014, Methods in molecular biology.

Purification of recombinant human tissue factor.

D. Yansura, J. Swartz, D. O'brien, 1989, Biochemistry.

A Radical Intermediate in Tyrosine Scission to the CO and CN− Ligands of FeFe Hydrogenase

W. Myers, R. D. Britt, J. Swartz, 2013, Science.

Cysteine as a ligand platform in the biosynthesis of the FeFe hydrogenase H cluster

R. D. Britt, J. Swartz, S. Cramer, 2015, Proceedings of the National Academy of Sciences.

The Cyanide Ligands of [FeFe] Hydrogenase: Pulse EPR Studies of 13C and 15N-Labeled H-Cluster

W. Myers, R. D. Britt, J. Swartz, 2014, Journal of the American Chemical Society.

New Insights into [FeFe] Hydrogenase Activation and Maturase Function

R. D. Britt, J. Swartz, Jon M. Kuchenreuther, 2012, PloS one.

Tyrosine, Cysteine, and S-Adenosyl Methionine Stimulate In Vitro [FeFe] Hydrogenase Activation

J. Stapleton, J. Swartz, Jon M. Kuchenreuther, 2009, PloS one.

BioHydrogen Generation by Genetically Engineered Microorganisms

A. Spormann, Chia-wei Wang, J. Swartz, 2022 .

The Radical SAM Enzyme HydG Requires Cysteine and a Dangler Iron for Generating an Organometallic Precursor to the [FeFe]-Hydrogenase H-Cluster.

R. D. Britt, J. Swartz, S. Cramer, 2016, Journal of the American Chemical Society.

Purification of acetate kinase by affinity chromatography.

M. C. Archer, J. Swartz, B. Solomon, 1978, Preparative biochemistry.

Chemical lysis of cyanobacteria

James R. Swartz, Kunal K. Mehta, J. Swartz, 2015, Journal of Biological Engineering.

Affinity Purification of Lipid Vesicles

J. Swartz, Jessica J Wuu, B. Peker, 2008, Biotechnology progress.

Oxalate improves protein synthesis by enhancing ATP supply in a cell-free system derived from Escherichia coli

Dong-Myung Kim, J. Swartz, 2000, Biotechnology Letters.

Improved Composition and Energy Supply for Bacterial Batch Systems

Dong-Myung Kim, J. Swartz, 2002 .

Solubility Partner IF2 Domain I Enables High Yield Synthesis of Transducible Transcription Factors in E. coli

J. Cooke, J. Swartz, Jieun Lee, 2011 .

Pluripotency transcription factor Sox2 is strongly adsorbed by heparin but requires a protein transduction domain for cell internalization.

Cem Albayrak, J. Swartz, William C. Yang, 2013, Biochemical and biophysical research communications.

Escherichia coli Plasminogen Activator in Expression of Active Human Tissue-Type

G. Georgiou, J. Swartz, J. Qiu, 2013 .

Genetic Analysis of Disulfide Isomerization in Escherichia coli: Expression of DsbC Is Modulated by RNase E-Dependent mRNA Processing

G. Georgiou, M. Cieslewicz, J. Swartz, 2004, Journal of bacteriology.

A comparison of the staircase voltammetric and polarographic responses of pyrazine and several substituted pyrazines in aqueous acid

J. Swartz, F. Anson, 1980 .

Genetic Approaches to the Detection of Contaminants in Escherichia coli Fermentations

N. Mcfarland, J. Swartz, 1998, Biotechnology progress.

Cell-Free Systems for Metabolic Engineering

J. Swartz, Kara A Calhoun, 2009 .

Cell-free co-production of an orthogonal transfer RNA activates efficient site-specific non-natural amino acid incorporation

Cem Albayrak, James R. Swartz, Cem Albayrak, 2013, Nucleic acids research.

Sequence Specific Modeling of E. coli Cell-Free Protein Synthesis.

Kara Calhoun, Jeffrey D Varner, Nicholas Horvath, 2018, ACS synthetic biology.

Production and stabilization of the trimeric influenza hemagglutinin stem domain for potentially broadly protective influenza vaccines

James R. Swartz, J. Swartz, Yuan Lu, 2013, Proceedings of the National Academy of Sciences.

A vaccine directed to B cells and produced by cell-free protein synthesis generates potent antilymphoma immunity

Ronald Levy, Shoshana Levy, S. Levy, 2012, Proceedings of the National Academy of Sciences.

Cell-free production of scFv fusion proteins: an efficient approach for personalized lymphoma vaccines.

Junhao Yang, Gregory Kanter, Ronald Levy, 2007, Blood.

Energy systems for ATP regeneration in cell-free protein synthesis reactions.

J. Swartz, Kara A Calhoun, James R Swartz, 2007, Methods in molecular biology.

An Economical Method for Cell‐Free Protein Synthesis using Glucose and Nucleoside Monophosphates

J. Swartz, Kara A Calhoun, James R Swartz, 2008, Biotechnology progress.

Thermodynamic evaluation of microbial growth

James R. Swartz, Henry Y. Wang, J. Swartz, 1976 .

Expression of Recombinant Proteins in Escherichia coli Using an Oxygen-Responsive Promoter

J. Bailey, C. Khosla, J. E. Curtis, 1990, Bio/Technology.

Advances in Escherichia coli production of therapeutic proteins.

J. Swartz, J R Swartz, 2001, Current opinion in biotechnology.

Virus‐like particles: Next‐generation nanoparticles for targeted therapeutic delivery

James R. Swartz, Maya Nagasawa, J. Swartz, 2017, Bioengineering & translational medicine.

Transforming biochemical engineering with cell-free biology

James R. Swartz, J. Swartz, 2012 .

Cell‐free synthesis of functional aquaporin Z in synthetic liposomes

J. Swartz, James R Swartz, Jessica J Wuu, 2009, Biotechnology and bioengineering.

Escherichia coli‐based cell free production of flagellin and ordered flagellin display on virus‐like particles

Wei Chan, J. Swartz, Yuan Lu, 2013, Biotechnology and bioengineering.

Cell‐free production of trimeric influenza hemagglutinin head domain proteins as vaccine antigens

H. Greenberg, J. Swartz, Yuan Lu, 2012, Biotechnology and bioengineering.

Simplifying and streamlining Escherichia coli‐based cell‐free protein synthesis

Kedar G. Patel, J. Swartz, James R Swartz, 2012, Biotechnology progress.

Surface functionalization of virus-like particles by direct conjugation using azide-alkyne click chemistry.

Kedar G. Patel, J. Swartz, James R Swartz, 2011, Bioconjugate chemistry.

An integrated cell-free metabolic platform for protein production and synthetic biology

Michael C Jewett, M. Jewett, J. Swartz, 2008, Molecular systems biology.

Escherichia coli‐based cell‐free synthesis of virus‐like particles

Bradley C. Bundy, J. Swartz, Bradley C Bundy, 2008, Biotechnology and bioengineering.

Development of cell‐free protein synthesis platforms for disulfide bonded proteins

J. Swartz, Aaron R. Goerke, James R. Swartz, 2008, Biotechnology and bioengineering.

Energizing cell-free protein synthesis with glucose metabolism.

J. Swartz, Kara A Calhoun, James R Swartz, 2005, Biotechnology and bioengineering.

Enhancing multiple disulfide bonded protein folding in a cell‐free system

J. Swartz, G. Yin, James R Swartz, 2004, Biotechnology and bioengineering.

Efficient production of a bioactive, multiple disulfide‐bonded protein using modified extracts of Escherichia coli

Dong-Myung Kim, J. Swartz, James R. Swartz, 2004, Biotechnology and bioengineering.

High‐level cell‐free synthesis yields of proteins containing site‐specific non‐natural amino acids

James R. Swartz, J. Swartz, Aaron R. Goerke, 2009, Biotechnology and bioengineering.

Solubility partner IF2 Domain I enables high yield synthesis of transducible transcription factors in Escherichia coli.

J. Cooke, J. Swartz, Jieun Lee, 2011, Protein expression and purification.

Cell-free production of transducible transcription factors for nuclear reprogramming.

J. Cooke, Kedar G. Patel, J. Swartz, 2009, Biotechnology and bioengineering.

Polyethylene Glycol Enhanced Protein Refolding

James R. Swartz, Daniel I. C. Wang, J. Swartz, 1992, Bio/Technology.

Localization of BiP to translating ribosomes increases soluble accumulation of secreted eukaryotic proteins in an Escherichia coli cell‐free system

J. Swartz, J. Bonomo, J. Welsh, 2011, Biotechnology and bioengineering.

Cell-free protein synthesis with prokaryotic combined transcription-translation.

Kim A Woodrow, Michael C Jewett, M. Jewett, 2004, Methods in molecular biology.

Functional properties of flagellin as a stimulator of innate immunity

J. Swartz, Yuan Lu, 2016, Scientific Reports.

An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics

G. Rao, G. Sittampalam, R. Lunsford, 2022, bioRxiv.

Regeneration of adenosine triphosphate from glycolytic intermediates for cell-free protein synthesis.

Dong-Myung Kim, J. Swartz, D. M. Kim, 2001, Biotechnology and bioengineering.

Mimicking the Escherichia coli cytoplasmic environment activates long‐lived and efficient cell‐free protein synthesis

M. Jewett, J. Swartz, James R. Swartz, 2004, Biotechnology and bioengineering.

A sequential expression system for high‐throughput functional genomic analysis

K. Woodrow, J. Swartz, 2007, Proteomics.

Streamlining Escherichia Coli S30 Extract Preparation for Economical Cell‐Free Protein Synthesis

J. Swartz, J. Zawada, James R. Swartz, 2008, Biotechnology progress.

Quantitative polysome analysis identifies limitations in bacterial cell-free protein synthesis.

Joseph D Puglisi, J. Puglisi, J. Swartz, 2005, Biotechnology and bioengineering.

Efficient disulfide bond formation in virus-like particles.

Bradley C. Bundy, J. Swartz, Bradley C Bundy, 2011, Journal of biotechnology.

Evidence for an additional disulfide reduction pathway in Escherichia coli.

J. Swartz, Kurtis G. Knapp, 2007, Journal of bioscience and bioengineering.

Effects of growth rate on cell extract performance in cell‐free protein synthesis

J. Swartz, J. Zawada, 2006, Biotechnology and bioengineering.

Single-Step Solubilization and Folding of IGF-1 Aggregates fromEscherichia coli

J. Swartz, J. Y. Chang, 1993 .

Expression of Active Human Tissue-Type Plasminogen Activator in Escherichia coli

J. Swartz, J. Qiu, George R. Georgiou, 1998, Applied and Environmental Microbiology.

Development of a Novel Virus-like Particle (VLP) Vaccine for Personalized B-Cell Lymphoma and Chronic Lymphocytic Leukemia Therapy

T. Theriault, J. Swartz, W. Chan, 2015 .

The exciting potential of modular nanoparticles for rapid development of highly effective vaccines

James R. Swartz, Julie A Fogarty, J. Swartz, 2018 .

Site-specific incorporation of p-propargyloxyphenylalanine in a cell-free environment for direct protein-protein click conjugation.

James R. Swartz, Bradley C. Bundy, J. Swartz, 2010, Bioconjugate chemistry.

Rapid expression of vaccine proteins for B-cell lymphoma in a cell-free system.

Junhao Yang, Gregory Kanter, Ronald Levy, 2005, Biotechnology and bioengineering.

High-Yield Expression of Heterologous [FeFe] Hydrogenases in Escherichia coli

J. Swartz, S. George, S. Cramer, 2010, PloS one.

Measurement of cell mass concentration with a continuous‐flow viscometer

James R. Swartz, Charles L. Cooney, C. Cooney, 1979 .

Chemical lysis of cyanobacteria

Kunal K. Mehta, J. Swartz, Niklaus H. Evitt, 2015, Journal of biological engineering.

Comparing the functional properties of the Hsp70 chaperones, DnaK and BiP.

J. Swartz, J. Bonomo, J. Welsh, 2010, Biophysical chemistry.

Broadening Horizons and Teaching Basic Biology Through Cell-Free Synthesis of Green Fluorescent Protein in a High School Laboratory Course

Cem Albayrak, J. Swartz, K. C. Jones, 2013, Journal of Science Education and Technology.

Broadening Horizons and Teaching Basic Biology Through Cell-Free Synthesis of Green Fluorescent Protein in a High School Laboratory Course

Cem Albayrak, K. C. Jones, James R. Swartz, 2013 .

Total amino acid stabilization during cell-free protein synthesis reactions.

J. Swartz, Kara A Calhoun, James R Swartz, 2006, Journal of biotechnology.

Maintaining rapid growth in moderate-density Escherichia coli fermentations.

James Swartz, J. Swartz, J. Zawada, 2005, Biotechnology and bioengineering.

Prolonging Cell‐Free Protein Synthesis by Selective Reagent Additions

Dong-Myung Kim, J. Swartz, D M Kim, 2000, Biotechnology progress.

Simultaneous expression and maturation of the iron‐sulfur protein ferredoxin in a cell‐free system

Chia-Wei Wang, J. Swartz, James R Swartz, 2006, Biotechnology and bioengineering.

Methanol Inhibition in Continuous Culture of Hansenula polymorpha

C. Cooney, J. Swartz, 1981, Applied and environmental microbiology.

Expanding biological applications using cell-free metabolic engineering: An overview.

J. Swartz, 2018, Metabolic engineering.

Cell-free production of Gaussia princeps luciferase--antibody fragment bioconjugates for ex vivo detection of tumor cells.

S. Levy, Kedar G. Patel, J. Swartz, 2009, Biochemical and biophysical research communications.

Amino acid stabilization for cell-free protein synthesis by modification of the Escherichia coli genome.

James Swartz, Kara Calhoun, J. Swartz, 2004, Metabolic engineering.

Production of heterologous proteins from recombinant DNA Escherichia coli in bench fermentors

J. Swartz, N. Lin, 1992 .

System analysis and improved [FeFe] hydrogenase O2 tolerance suggest feasibility for photosynthetic H2 production.

J. Swartz, Ja-Hyup Koo, 2018, Metabolic engineering.

Evolution of an [FeFe] hydrogenase with decreased oxygen sensitivity

James R. Swartz, J. Swartz, Phillip R. Smith, 2012 .

Cell-free H-cluster Synthesis and [FeFe] Hydrogenase Activation: All Five CO and CN− Ligands Derive from Tyrosine

J. Swartz, S. George, S. Cramer, 2011, PloS one.

Cell‐free synthesis and maturation of [FeFe] hydrogenases

J. Stapleton, J. Swartz, Jon M. Kuchenreuther, 2008, Biotechnology and bioengineering.

Cell-free metabolic engineering promotes high-level production of bioactive Gaussia princeps luciferase.

S. Gambhir, J. Swartz, A. Loening, 2008, Metabolic engineering.

Electrochemistry of the intensely green complexes formed by the reaction of chromium(2+) with pyrazine ("pyrazine green"), pyrazinecarboxamide, and pyrazinecarboxylic acid

J. Swartz, F. Anson, 1981 .

A Cell-Free Microtiter Plate Screen for Improved [FeFe] Hydrogenases

James A. Stapleton, James R. Swartz, J. Stapleton, 2010, PloS one.

Direct polymerization of proteins.

Cem Albayrak, J. Swartz, 2014, ACS synthetic biology.

Characterization of [FeFe] Hydrogenase O2 Sensitivity Using a New, Physiological Approach*

Kunal K. Mehta, J. Swartz, Ja-Hyup Koo, 2016, The Journal of Biological Chemistry.

Rapid Expression and Purification of 100 nmol Quantities of Active Protein Using Cell‐Free Protein Synthesis

M. Jewett, J. Swartz, 2008, Biotechnology progress.

Cell-free Protein Synthesis : methods and protocols

James R. Swartz, Alexander S. Spirin, A. Spirin, 2008 .

High yield cell-free production of integral membrane proteins without refolding or detergents.

J. Swartz, James R Swartz, Jessica J Wuu, 2008, Biochimica et biophysica acta.

Development of a synthetic pathway to convert glucose to hydrogen using cell free extracts

Kunal K. Mehta, J. Swartz, Phillip R. Smith, 2015 .

Increasing PCR Fragment Stability and Protein Yields in a Cell-Free System with Genetically Modified Escherichia coli Extracts

James Swartz, K. Woodrow, J. Swartz, 2005, Journal of Molecular Microbiology and Biotechnology.

Metabolic oscillations in an E. coli fermentation.

B. Snedecor, T. Ryll, J. Swartz, 2001, Biotechnology and bioengineering.

Sequence Specific Modeling of E. coli Cell-Free Protein Synthesis

J. Varner, J. Wayman, J. Swartz, 2017, bioRxiv.

Streamlined circular proximity ligation assay provides high stringency and compatibility with low-affinity antibodies

Henrik H. J. Persson, J. Horecka, Roxana Jalili, 2018, Proceedings of the National Academy of Sciences.

Escherichia coli-based production of a tumor idiotype antibody fragment--tetanus toxin fragment C fusion protein vaccine for B cell lymphoma.

S. Levy, Kedar G. Patel, J. Swartz, 2011, Protein expression and purification.

Cell-Free Protein Expression

James R. Swartz, J. Swartz, 2011, Springer Berlin Heidelberg.

Simplifying and streamlining Escherichia coli‐based cell‐free protein synthesis

Kedar G. Patel, J. Swartz, H. E. Wong, 2012, Biotechnology progress (Print).

Cell‐free synthesis of proteins that require disulfide bonds using glucose as an energy source

J. Swartz, Kurtis G. Knapp, Aaron R. Goerke, 2007, Biotechnology and bioengineering.

Efficient disulfide bond formation in virus-like particles.

Bradley C. Bundy, J. Swartz, 2011, Journal of biotechnology.