A. Sheftel

发表

TIBS 1335 No . of Pages 12 Key Figure Mechanisms Involved in the Removal of ‘ Toxic Heme ’ from the Circulation

A. English, D. Garcia-Santos, P. Ponka, 2017 .

Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells

D. Garcia-Santos, P. Ponka, A. Sheftel, 2017, Haematologica.

Do Mammalian Cells Really Need to Export and Import Heme?

A. English, D. Garcia-Santos, P. Ponka, 2017, Trends in biochemical sciences.

Heme oxygenase 1 is expressed in murine erythroid cells where it controls the level of regulatory heme.

D. Garcia-Santos, Monika Horváthová, P. Ponka, 2014, Blood.

Erythroid Iron Metabolism

P. Ponka, A. Sheftel, 2012 .

HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress

P. Sorensen, A. Gramolini, J. Penninger, 2014, Nature Communications.

Direct interorganellar transfer of iron from endosome to mitochondrion.

Claire M. Brown, O. Shirihai, P. Ponka, 2006, Blood.

Mitochondrial Iron Metabolism and Sideroblastic Anemia

D. Richardson, J. Prchal, P. Ponka, 2009, Acta Haematologica.

Prognostic usefulness of insulin-like growth factor-binding protein 7 in heart failure with reduced ejection fraction: a novel biomarker of myocardial diastolic function?

A. Sheftel, A. Baggish, R. Weiner, 2014, The American journal of cardiology.

Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria.

P. Ponka, A. Sheftel, An-Sheng Zhang, 2005, Blood.

Human Ind1, an Iron-Sulfur Cluster Assembly Factor for Respiratory Complex I

J. Balk, I. Wittig, H. Elsässer, 2009, Molecular and Cellular Biology.

Ferritin does not donate its iron for haem synthesis in macrophages.

P. Ponka, A. Sheftel, Marc R. Mikhael, 2010, The Biochemical journal.

Nramp1 equips macrophages for efficient iron recycling.

P. Ponka, A. Sheftel, S. Soe-Lin, 2008, Experimental hematology.

Non-heme Induction of Heme Oxygenase-1 Does Not Alter Cellular Iron Metabolism*

P. Ponka, A. Sheftel, Sangwon F. Kim, 2007, Journal of Biological Chemistry.

protein expression and iron uptake Functional consequences of the human DMT1 (SLC11A2) mutation on

V. Divoky, D. Pospíšilová, A. Sheftel, 2013 .

involvement in iron targeting to mitochondria Intracellular kinetics of iron in reticulocytes: evidence for endosome

P. Ponka, A. Sheftel, An-Sheng Zhang, 2013 .

The anemia of "haemoglobin-deficit" (hbd/hbd) mice is caused by a defect in transferrin cycling.

P. Ponka, A. Sheftel, An-Sheng Zhang, 2006, Experimental hematology.

Functional consequences of the human DMT1 (SLC11A2) mutation on protein expression and iron uptake.

V. Divoky, D. Pospíšilová, Guangjun Nie, 2005, Blood.

Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.

A. Vashisht, J. Wohlschlegel, R. Lill, 2013, Cell metabolism.

Erythroid cell mitochondria receive endosomal iron by a "kiss-and-run" mechanism.

A. Mason, Amel Hamdi, P. Ponka, 2016, Biochimica et biophysica acta.

Chapter 12 Controlled expression of iron-sulfur cluster assembly components for respiratory chain complexes in mammalian cells.

R. Lill, A. Sheftel, O. Stehling, 2009, Methods in enzymology.

Iron–sulfur proteins in health and disease

R. Lill, A. Sheftel, O. Stehling, 2010, Trends in Endocrinology & Metabolism.

The human mitochondrial ISCA1, ISCA2, and IBA57 proteins are required for [4Fe-4S] protein maturation

H. Elsässer, R. Lill, A. Sheftel, 2012, Molecular biology of the cell.

Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol

D. Richardson, P. Ponka, A. Sheftel, 2010, Proceedings of the National Academy of Sciences.

The long history of iron in the Universe and in health and disease.

A. Mason, P. Ponka, A. Sheftel, 2012, Biochimica et biophysica acta.

Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation

Guangjun Nie, A. Sheftel, Yan-zhong Chang, 2014, Cellular and Molecular Life Sciences.

Iron targeting to mitochondria in erythroid cells.

P. Ponka, A. Sheftel, A. Zhang, 2001, Biochemical Society transactions.

Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis

H. Elsässer, R. Lill, A. Sheftel, 2010, Proceedings of the National Academy of Sciences.

The power plant of the cell is also a smithy: The emerging role of mitochondria in cellular iron homeostasis

R. Lill, A. Sheftel, 2009, Annals of medicine.

and changes cellular iron homeostasis Overexpression of mitochondrial ferritin causes cytosolic iron depletion

Guangjun Nie, P. Ponka, A. Sheftel, 2013 .

In vivo tumor growth is inhibited by cytosolic iron deprivation caused by the expression of mitochondrial ferritin.

Guangjun Nie, K. Pantopoulos, P. Ponka, 2006, Blood.

Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis.

Guangjun Nie, P. Ponka, A. Sheftel, 2004, Blood.

Erythropoiesis, Hemoglobin Synthesis, and Erythroid Mitochondrial Iron Homeostasis

M. Koury, P. Ponka, A. Sheftel, 2013 .

Iron regulatory protein‐independent regulation of ferritin synthesis by nitrogen monoxide

P. Ponka, A. Sheftel, M. Schranzhofer, 2006, The FEBS journal.

Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation

Guangjun Nie, A. Sheftel, Yan-zhong Chang, 2014, Cellular and Molecular Life Sciences.

It's hepcidin again, but is it the only master?

P. Ponka, A. Sheftel, 2006 .

Prognostic usefulness of insulin-like growth factor-binding protein 7 in heart failure with reduced ejection fraction: a novel biomarker of myocardial diastolic function?

A. Sheftel, A. Baggish, R. Weiner, 2014, The American journal of cardiology.

Heme oxygenase 1 is expressed in murine erythroid cells where it controls the level of regulatory heme.

P. Ponka, A. Sheftel, M. Schranzhofer, 2014, Blood.