F. Osman

PKR activation and eIF2α phosphorylation mediate human globin mRNA splicing at spliceosome assembly

Smadar Cohen-Chalamish, L. Ilan, F. Osman, 2017, Cell Research.

2-Aminopurine selectively inhibits splicing of tumor necrosis factor alpha mRNA

F. Osman, R. Kaempfer, N. Jarrous, 1996, Molecular and cellular biology.

Superantigens hyperinduce inflammatory cytokines by enhancing the B7-2/CD28 costimulatory receptor interaction

F. Osman, R. Kaempfer, Andrey Popugailo, 2016, Proceedings of the National Academy of Sciences.

An Ancient Pseudoknot in TNF-α Pre-mRNA Activates PKR, Inducing eIF2α Phosphorylation that Potently Enhances Splicing.

B. Masquida, F. Osman, Lise Sarah Namer, 2017, Cell reports.

A cis-acting element in the 3'-untranslated region of human TNF-alpha mRNA renders splicing dependent on the activation of protein kinase PKR.

F. Osman, Y. Ben-Asouli, R. Kaempfer, 1999, Genes & development.

Down-regulation of human tumor necrosis factor-beta gene expression by cells with suppressive activity.

F. Osman, R. Kaempfer, D. Aframian, 1996, Immunology letters.

Dynamic refolding of IFN-gamma mRNA enables it to function as PKR activator and translation template.

Smadar Cohen-Chalamish, F. Osman, Lise Sarah Namer, 2009, Nature chemical biology.

Control of mRNA Splicing by Intragenic RNA Activators of Stress Signaling: Potential Implications for Human Disease

Smadar Cohen-Chalamish, L. Ilan, F. Osman, 2019, Front. Genet..

An Ancient Pseudoknot in TNF-α Pre-mRNA Activates PKR, Inducing eIF2α Phosphorylation that Potently Enhances Splicing.

B. Masquida, F. Osman, Lise Sarah Namer, 2017, Cell reports.