Xiaojing Yuan

发表

M. Fleming, Xiaojing Yuan, I. Hamza, 2013, Current opinion in chemical biology.

Characterization of plasma labile heme in hemolytic conditions

J. Goncalves, C. Gomes, S. Leal, 2017, The FEBS journal.

Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation.

Xianglei Zhang, Guofeng Chen, Yechun Xu, 2020, Journal of medicinal chemistry.

Heme oxygenase-2 (HO-2) binds and buffers labile heme, which is largely oxidized, in human embryonic kidney cells

Liu Liu, A. Fleischhacker, S. Ragsdale, 2021, bioRxiv.

Heme oxygenase-2 (HO-2) binds and buffers labile ferric heme in human embryonic kidney cells

Liu Liu, A. Fleischhacker, S. Ragsdale, 2021, The Journal of biological chemistry.

Structural basis for promotion of duodenal iron absorption by enteric ferric reductase with ascorbate

H. Sugimoto, K. Hirata, T. Urano, 2018, Communications Biology.

Gorge Motions of Acetylcholinesterase Revealed by Microsecond Molecular Dynamics Simulations

Yechun Xu, Xiaojing Yuan, Wanling Song, 2017, Scientific Reports.

Regulation of intracellular heme trafficking revealed by subcellular reporters

J. Phillips, Xiaojing Yuan, I. Hamza, 2016, Proceedings of the National Academy of Sciences.

Hemozoin produced by mammals confers heme tolerance

H. Sugimoto, D. Bodine, J. Phillips, 2019, bioRxiv.

Transport in HRG-1-related Topologically Conserved Residues Direct Metabolism :

Xiaojing Yuan, I. Hamza, C. Philpott, 2012 .

Topologically Conserved Residues Direct Heme Transport in HRG-1-related Proteins*

Xiaojing Yuan, I. Hamza, C. Philpott, 2011, The Journal of Biological Chemistry.

HRG-9 homologues regulate haem trafficking from haem-enriched compartments

Mathilda M. Willoughby, Xiaojing Yuan, I. Hamza, 2022, Nature.

Discovery of a Novel Series of Imidazo[1,2-a]pyrimidine Derivatives as Potent and Orally Bioavailable Lipoprotein-Associated Phospholipase A2 Inhibitors.

Yechun Xu, Jianhua Shen, Xiaojing Yuan, 2015, Journal of medicinal chemistry.

Heme dynamics and trafficking factors revealed by genetically encoded fluorescent heme sensors

Osiris Martinez-Guzman, Xiaojing Yuan, I. Hamza, 2016, Proceedings of the National Academy of Sciences.

Heme Uptake by Leishmania amazonensis Is Mediated by the Transmembrane Protein LHR1

C. Huynh, D. C. Miguel, Xiaojing Yuan, 2012, PLoS pathogens.

HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis.

M. Fleming, Xiaojing Yuan, I. Hamza, 2013, Cell metabolism.

Cys Links Heme: Stereo-orientation of Heme Transfer in Cytochrome c Biogenesis.

Xiaojing Yuan, I. Hamza, 2018, Journal of molecular biology.

Inter-organ signaling by HRG-7 promotes systemic heme homeostasis

M. Krause, Xiaojing Yuan, I. Hamza, 2017, Nature Cell Biology.

Inter-organ signalling by HRG-7 promotes systemic haem homeostasis

M. Krause, Xiaojing Yuan, I. Hamza, 2017 .

Heme acquisition in the parasitic filarial nematode Brugia malayi

B. Slatko, J. Foster, D. Voronin, 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The Heme Transport Capacity of LHR1 Determines the Extent of Virulence in Leishmania amazonensis

D. C. Miguel, Xiaojing Yuan, I. Hamza, 2015, PLoS neglected tropical diseases.

FUNCTIONAL INSIGHTS INTO HRG-1-MEDIATED HEME TRANSPORT

Xiaojing Yuan, 2012 .

In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP-AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing

Yechun Xu, Xiaojing Yuan, Hongbin Sun, 2020, J. Chem. Inf. Model..

Structural basis for promotion of duodenal iron absorption by enteric ferric reductase with ascorbate

H. Sugimoto, K. Hirata, T. Urano, 2018, Communications Biology.

Structural basis for ligand recognition of the human thromboxane A2 receptor

Hui Zhang, Qiang Zhao, Yechun Xu, 2018, Nature Chemical Biology.

Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2.

Qiufeng Liu, Jianhua Shen, Yechun Xu, 2017, Journal of medicinal chemistry.

Structural and Thermodynamic Characterization of Protein-Ligand Interactions Formed between Lipoprotein-Associated Phospholipase A2 and Inhibitors.

Yechun Xu, Jianhua Shen, Qiu-feng Liu, 2016, Journal of medicinal chemistry.

Recent Trends and Applications of Molecular Modeling in GPCR–Ligand Recognition and Structure-Based Drug Design

Yechun Xu, Xiaojing Yuan, Yechun Xu, 2018, International journal of molecular sciences.

The GUS reporter-aided analysis of the promoter activities of a rice metallothionein gene reveals different regulatory regions responsible for tissue-specific and inducible expression in transgenic Arabidopsis

Ai-Min Wu, H. Gu, L. Qu, 2007, Transgenic Research.