F. Harbinski

发表

Chemical Genetics Identify eIF2α Kinase Heme Regulated Inhibitor as Anti-Cancer Target

J. Supko, S. Denoyelle, J. Halperin, 2011, Nature chemical biology.

Small-molecule targeting of translation initiation for cancer therapy

S. Singer, J. Halperin, B. Aktas, 2013, Oncotarget.

Target identification for a Hedgehog pathway inhibitor reveals the receptor GPR39.

Jeffrey A. Porter, P. Grandi, H. Ruffner, 2014, Nature chemical biology.

SMOOT libraries and phage-induced directed evolution of Cas9 to engineer reduced off-target activity

V. Myer, Katherine Loveluck, H. Jayaram, 2020, PloS one.

Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury.

Stephen M. Canham, John A. Tallarico, J. Tallarico, 2021, Cell chemical biology.

Ascospore morphology is a poor predictor of the phylogenetic relationships of Neurospora and Gelasinospora.

J. W. Taylor, J. Dettman, F. Harbinski, 2001, Fungal genetics and biology : FG & B.

Novel arylsulfoanilide-oxindole hybrid as an anticancer agent that inhibits translation initiation.

J. Halperin, A. Natarajan, M. Chorev, 2004, Journal of medicinal chemistry.

3,3-diaryl-1,3-dihydroindol-2-ones as antiproliferatives mediated by translation initiation inhibition.

W. Christ, J. Halperin, A. Natarajan, 2004, Journal of medicinal chemistry.

Synthesis and biological evaluation of thiazolidine-2,4-dione and 2,4-thione derivatives as inhibitors of translation initiation.

W. Christ, J. Halperin, A. Natarajan, 2004, Bioorganic & medicinal chemistry letters.

Structure-activity requirements for the antiproliferative effect of troglitazone derivatives mediated by depletion of intracellular calcium.

W. Christ, J. Halperin, A. Natarajan, 2004, Bioorganic & medicinal chemistry letters.

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

John A. Tallarico, M. Schirle, Christopher J. Wilson, 2014, Nature Cell Biology.

Identification of Mixed Lineage Leukemia 1(MLL1) Protein as a Coactivator of Heat Shock Factor 1(HSF1) Protein in Response to Heat Shock Protein 90 (HSP90) Inhibition*

J. Yu, Guizhi Yang, Jianjun Yu, 2014, The Journal of Biological Chemistry.

Rescue screens with secreted proteins reveal compensatory potential of receptor tyrosine kinases in driving cancer growth.

Jeffrey A. Porter, W. Sellers, Christopher J. Wilson, 2012, Cancer discovery.

TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A

Caitlin M. Rodriguez, Beryl B. Cummings, Laura R. Ganser, 2021, Nature.

High-Order Drug Combinations Are Required to Effectively Kill Colorectal Cancer Cells.

Joel Greshock, Levi A Garraway, Fred Harbinski, 2016, Cancer research.

Reporter enzyme inhibitor study to aid assembly of orthogonal reporter gene assays.

D. Auld, K. Wood, N. Karassina, 2013, ACS chemical biology.

Metabolic Enzyme Sulfotransferase 1A1 Is the Trigger for N-Benzyl Indole Carbinol Tumor Growth Suppression.

Jeffrey A. Porter, K. Venkatesan, Christopher J. Wilson, 2015, Chemistry & biology.

Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C

Michael S. Goldberg, J. Jenkins, W. Forrester, 2017, The Journal of clinical investigation.

Metabolic Enzyme Sulfotransferase 1 A 1 Is the Trigger for N-Benzyl Indole Carbinol Tumor Growth Suppression Highlights

Jeffrey A. Porter, K. Venkatesan, Christopher J. Wilson, 2022 .

Jenkins-CI, an Open-Source Continuous Integration System, as a Scientific Data and Image-Processing Platform

Xian Zhang, Jeremy L. Jenkins, Imtiaz Hossain, 2016, SLAS discovery : advancing life sciences R & D.

Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C

Michael S. Goldberg, J. Jenkins, W. Forrester, 2017, The Journal of clinical investigation.

Small-molecule targeting of translation initiation for cancer therapy

S. Singer, J. Halperin, B. Aktas, 2013, Oncotarget.