E. Wang

发表

Hemin Binds to Human Cytoplasmic Arginyl-tRNA Synthetase and Inhibits Its Catalytic Activity*

Fang Yang, X. Xia, H. Lei, 2010, The Journal of Biological Chemistry.

Commonality and diversity in tRNA substrate recognition in t6A biogenesis by eukaryotic KEOPSs

E. Wang, Li Zhou, Meirong Chen, 2022, Nucleic acids research.

Molecular basis for t6A modification in human mitochondria

E. Wang, Jing-Bo Zhou, Xiao-Long Zhou, 2020, Nucleic acids research.

The Yin and Yang of tRNA: proper binding of acceptor end determines the catalytic balance of editing and aminoacylation

G. Eriani, E. Wang, Wei-Qun Yan, 2013, Nucleic acids research.

C-terminal Domain of Leucyl-tRNA Synthetase from Pathogenic Candida albicans Recognizes both tRNASer and tRNALeu*

E. Wang, Xiao-Long Zhou, Quan-Quan Ji, 2015, The Journal of Biological Chemistry.

Aminoacylation and translational quality control strategy employed by leucyl-tRNA synthetase from a human pathogen with genetic code ambiguity

E. Wang, Xiao-Long Zhou, M. Tan, 2013, Nucleic acids research.

Coexistence of bacterial leucyl-tRNA synthetases with archaeal tRNA binding domains that distinguish tRNALeu in the archaeal mode

E. Wang, Xiao-Long Zhou, M. Tan, 2014, Nucleic acids research.

Gene 5.5 protein of bacteriophage T7 in complex with Escherichia coli nucleoid protein H-NS and transfer RNA masks transfer RNA priming in T7 DNA replication

C. Richardson, E. Wang, Seung-Joo Lee, 2012, Proceedings of the National Academy of Sciences.

Self-protective responses to norvaline-induced stress in a leucyl-tRNA synthetase editing-deficient yeast strain

C. Chi, E. Wang, Quan-Quan Ji, 2017, Nucleic acids research.

Crucial role of the C-terminal domain of Mycobacterium tuberculosis leucyl-tRNA synthetase in aminoacylation and editing

E. Wang, Q. Hu, Qian Huang, 2012, Nucleic acids research.

A naturally occurring nonapeptide functionally compensates for the CP1 domain of leucyl-tRNA synthetase to modulate aminoacylation activity.

E. Wang, Xin Chen, Wei-Qun Yan, 2012, The Biochemical journal.

Two tyrosine residues outside the editing active site in Giardia lamblia leucyl-tRNA synthetase are essential for the post-transfer editing.

E. Wang, Xiao-Long Zhou, E. Wang, 2009, Biochemical and biophysical research communications.

Two distinct domains of the beta subunit of Aquifex aeolicus leucyl-tRNA synthetase are involved in tRNA binding as revealed by a three-hybrid selection.

G. Eriani, F. Martin, Yong-Gang Zheng, 2004, Nucleic acids research.

Tertiary structure base pairs between D- and TpsiC-loops of Escherichia coli tRNA(Leu) play important roles in both aminoacylation and editing.

E. Wang, Xing Du, 2003, Nucleic acids research.

Two non-redundant fragments in the N-terminal peptide of human cytosolic methionyl-tRNA synthetase were indispensable for the multi-synthetase complex incorporation and enzyme activity.

E. Wang, P. Yao, Xin Chen, 2009, Biochimica et biophysica acta.

Nitrosative stress inhibits aminoacylation and editing activities of mitochondrial threonyl-tRNA synthetase by S-nitrosation

E. Wang, Xiao-Long Zhou, Yuying Zhang, 2020, Nucleic acids research.

Arginyl-tRNA synthetase with signature sequence KMSK from Bacillus stearothermophilus.

E. Wang, Juan Li, Yong-Neng Yao, 2003, The Biochemical journal.

Identification of determinants for tRNA substrate recognition by Escherichia coli C/U34 2′-O-methyltransferase

E. Wang, Xiao-Long Zhou, Z. Fang, 2015, RNA biology.

Modulation of Aminoacylation and Editing Properties of Leucyl-tRNA Synthetase by a Conserved Structural Module*

G. Eriani, E. Wang, Wei-Qun Yan, 2015, The Journal of Biological Chemistry.

Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6

E. Wang, Ru-Juan Liu, T. Long, 2017, Nucleic acids research.

Crystallization and preliminary X-ray diffraction analysis of E. coli arginyl-tRNA synthetase in complex form with a tRNAArg

X. Xia, E. Wang, A. Azzi, 2006, Amino Acids.

Calpain Cleaves Most Components in the Multiple Aminoacyl-tRNA Synthetase Complex and Affects Their Functions

G. Eriani, H. Lei, E. Wang, 2015, The Journal of Biological Chemistry.

Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond

S. Cusack, Jinzhong Lin, A. Palencia, 2020, Nucleic acids research.

Degenerate Connective Polypeptide 1 (CP1) Domain from Human Mitochondrial Leucyl-tRNA Synthetase*

M. Wang, E. Wang, Xiao-Long Zhou, 2015, The Journal of Biological Chemistry.

Position 34 of tRNA is a discriminative element for m5C38 modification by human DNMT2

Hao Li, E. Wang, Hao Li, 2021, Nucleic acids research.

Archaeal NSUN6 catalyzes m5C72 modification on a wide-range of specific tRNAs

E. Wang, Ru-Juan Liu, T. Long, 2018, Nucleic acids research.

Acetylation of lysine ϵ-amino groups regulates aminoacyl-tRNA synthetase activity in Escherichia coli

Fang Yang, E. Wang, Wei-Qun Yan, 2017, The Journal of Biological Chemistry.

In vivo identification of essential nucleotides in tRNALeu to its functions by using a constructed yeast tRNALeu knockout strain

G. Eriani, E. Wang, P. Yao, 2012, Nucleic acids research.

Crystallization and preliminary X‐ray diffraction analysis of arginyl‐tRNA synthetase from Escherichia coli

R. Campbell, Sheng-Xiang Lin, E. Wang, 1997, Protein science : a publication of the Protein Society.

Molecular basis for human mitochondrial tRNA m3C modification by alternatively spliced METTL8

E. Wang, Meirong Chen, Jin-Tao Wang, 2022, Nucleic acids research.

A threonyl-tRNA synthetase-like protein has tRNA aminoacylation and editing activities

Yun Chen, E. Wang, Xiao-Long Zhou, 2018, Nucleic acids research.

LeuRS can leucylate type I and type II tRNALeus in Streptomyces coelicolor

E. Wang, Quan-Quan Ji, Qian Huang, 2019, Nucleic acids research.

Identification of Lethal Mutations in Yeast Threonyl-tRNA Synthetase Revealing Critical Residues in Its Human Homolog*

G. Eriani, H. Lei, E. Wang, 2014, The Journal of Biological Chemistry.

Acetylation of lysine (cid:2) -amino groups regulates aminoacyl-tRNA synthetase activity in Escherichia coli

Fang Yang, E. Wang, W. Yan, 2017 .

Overproduction and purification of glutaryl 7-amino cephalosporanic acid acylase.

W. Jiang, E. Wang, G. Zhao, 1998, Protein expression and purification.

Editing activity for eliminating mischarged tRNAs is essential in mammalian mitochondria

M. Poutanen, E. Wang, Fu-Ping Zhang, 2017, Nucleic acids research.

Translational fidelity maintenance preventing Ser mis-incorporation at Thr codon in protein from eukaryote

E. Wang, Xiao-Long Zhou, M. Tan, 2012, Nucleic acids research.

Newly acquired N-terminal extension targets threonyl-tRNA synthetase-like protein into the multiple tRNA synthetase complex

Yun Chen, E. Wang, P. Fang, 2019, Nucleic acids research.

Functional characterization of leucine-specific domain 1 from eukaryal and archaeal leucyl-tRNA synthetases.

G. Eriani, E. Wang, Xiao-Long Zhou, 2010, The Biochemical journal.

A dual role of human tRNA methyltransferase hTrmt13 in regulating translation and transcription

Beisi Xu, Hao Li, E. Wang, 2021, The EMBO journal.

ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing

Chuan He, T. Pan, Ziyang Hao, 2021, Nature Cell Biology.

Instability of the mitochondrial alanyl-tRNA synthetase underlies fatal infantile-onset cardiomyopathy

Robert W. Taylor, Carol J. Saunders, C. Saunders, 2018, Human molecular genetics.

The C-terminal Appended Domain of Human Cytosolic Leucyl-tRNA Synthetase Is Indispensable in Its Interaction with Arginyl-tRNA Synthetase in the Multi-tRNA Synthetase Complex*

En-Duo Wang, Yong-Gang Zheng, E. Wang, 2005, Journal of Biological Chemistry.

Peripheral insertion modulates the editing activity of the isolated CP1 domain of leucyl-tRNA synthetase.

G. Eriani, E. Wang, M. Tan, 2011, The Biochemical journal.

Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations.

Peng-Yuan Yang, Wei Xu, E. Wang, 2018, Cell metabolism.

Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase

Xin Chen, Min Tan, Peng Yao, 2010, Nucleic Acids Res..

Hearing impairment-associated KARS mutations lead to defects in aminoacylation of both cytoplasmic and mitochondrial tRNALys

E. Wang, Siqi Wu, P. Fang, 2020, Science China Life Sciences.

Mutations in KARS cause early‐onset hearing loss and leukoencephalopathy: Potential pathogenic mechanism

E. Wang, Tao Yang, Xiao-Long Zhou, 2017, Human mutation.

In vivo post-translational processing and subunit reconstitution of cephalosporin acylase from Pseudomonas sp. 130.

W. Jiang, E. Wang, G. Zhao, 1999, European journal of biochemistry.

The processing of human mitochondrial leucyl‐tRNA synthetase in the insect cells

E. Wang, Xiang-fu Wu, Yong-Neng Yao, 2003, FEBS letters.

Modifications of the human tRNA anticodon loop and their associations with genetic diseases

E. Wang, Jing-Bo Zhou, Xiao-Long Zhou, 2021, Cellular and Molecular Life Sciences.

The human tRNA taurine modification enzyme GTPBP3 is an active GTPase linked to mitochondrial diseases

E. Wang, Xiao-Long Zhou, Hong Xu, 2021, Nucleic acids research.

Multilevel functional and structural defects induced by two pathogenic mitochondrial tRNA mutations.

M. Wang, G. Eriani, E. Wang, 2013, The Biochemical journal.

Heme regulates protein homeostasis at transcription, protein translation, and degradation levels

E. Wang, Fang-Xiao Yang, E. Wang, 2010, Frontiers in Biology.

Escherichia coli tRNA4Arg(UCU) induces a constrained conformation of the crucial Ω-loop of arginyl-tRNA synthetase

G. Zhu, E. Wang, Yong-Neng Yao, 2004 .

Sequence-specific and Shape-selective RNA Recognition by the Human RNA 5-Methylcytosine Methyltransferase NSun6*

E. Wang, Xiao-Long Zhou, Ru-Juan Liu, 2016, The Journal of Biological Chemistry.

Intellectual disability‐associated gene ftsj1 is responsible for 2′‐O‐methylation of specific tRNAs

E. Wang, Yaping Liu, Ru-Juan Liu, 2020, EMBO reports.

Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase

Meng Wang, Qing-Hua Hu, En-Duo Wang, 2013, Scientific Reports.

The tRNA recognition mechanism of the minimalist SPOUT methyltransferase, TrmL

E. Wang, Xiao-Long Zhou, Meng Wang, 2013, Nucleic acids research.

Two forms of human cytoplasmic arginyl-tRNA synthetase produced from two translation initiations by a single mRNA.

Yong-Gang Zheng, E. Wang, Hui Wei, 2006, Biochemistry.

Reduction of mitochondrial tRNALeu(UUR) aminoacylation by some MELAS‐associated mutations

Yong-Gang Zheng, E. Wang, Yong-Neng Yao, 2004, FEBS letters.

E292 Is Important for the Aminoacylation Activity of Escherichia coli Leucyl-tRNA Synthetase

E. Wang, Xing Du, 2003, Journal of protein chemistry.

The G3-U70-independent tRNA recognition by human mitochondrial alanyl-tRNA synthetase

E. Wang, Jing-Bo Zhou, Xiao-Long Zhou, 2019, Nucleic acids research.

Distinct pathogenic mechanisms of various RARS1 mutations in Pelizaeus-Merzbacher-like disease

G. Eriani, E. Wang, Xiao-Long Zhou, 2021, Science China Life Sciences.

A Human Disease-causing Point Mutation in Mitochondrial Threonyl-tRNA Synthetase Induces Both Structural and Functional Defects*

G. Eriani, E. Wang, Xiao-Long Zhou, 2016, The Journal of Biological Chemistry.

tRNA-independent Pretransfer Editing by Class I Leucyl-tRNA Synthetase*

Peng Yao, Gilbert Eriani, En-Duo Wang, 2009, Journal of Biological Chemistry.

Structure of Escherichia coli Arginyl-tRNA Synthetase in Complex with tRNAArg: Pivotal Role of the D-loop.

R. Giegé, Rongguang Zhang, Sheng-Xiang Lin, 2018, Journal of molecular biology.

Interdomain communication modulates the tRNA-dependent pre-transfer editing of leucyl-tRNA synthetase.

E. Wang, Xin Chen, Xiao-Long Zhou, 2013, The Biochemical journal.

Expression, purification, and characterization of a new heterotetramer structure of leucyl-tRNA synthetase from Aquifex aeolicus in Escherichia coli.

G. Eriani, D. Moras, E. Wang, 2006, Protein expression and purification.

Leucyl-tRNA Synthetase from the Hyperthermophilic Bacterium Aquifex aeolicus Recognizes Minihelices*

E. Wang, Ming-Wei Zhao, Min-Gang Xu, 2004, Journal of Biological Chemistry.

Leucyl-tRNA Synthetase Consisting of Two Subunits from Hyperthermophilic Bacteria Aquifex aeolicus *

G. Eriani, F. Martin, E. Wang, 2002, The Journal of Biological Chemistry.

Study on the Overexpression of the Gene Encoding Arginyl-tRNA Synthetase under Induction.

X. Xia, E. Wang, Jin-Fu Wu, 1998, Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica.

tRNA recognition by a bacterial tRNA Xm32 modification enzyme from the SPOUT methyltransferase superfamily

E. Wang, Xiao-Long Zhou, Ru-Juan Liu, 2015, Nucleic acids research.

A minimalist mitochondrial threonyl-tRNA synthetase exhibits tRNA-isoacceptor specificity during proofreading

M. Wang, G. Eriani, Yun Chen, 2014, Nucleic Acids Research.

A bridge between the aminoacylation and editing domains of leucyl-tRNA synthetase is crucial for its synthetic activity

H. Lei, E. Wang, P. Yao, 2014, RNA.

Two novel engineered bacteria for secretory expression of glutaryl 7-amino-cephalosporanic acid acylase

Weihong Jiang, Yong-Gang Zheng, E. Wang, 2001, Biotechnology Letters.

A natural non-Watson–Crick base pair in human mitochondrial tRNAThr causes structural and functional susceptibility to local mutations

E. Wang, Xiao-Long Zhou, Yong Wang, 2018, Nucleic acids research.

Cryptosporidium and Toxoplasma Parasites Are Inhibited by a Benzoxaborole Targeting Leucyl-tRNA Synthetase

J. Gut, P. Rosenthal, A. Bougdour, 2016, Antimicrobial Agents and Chemotherapy.

Substrate‐induced conformational changes in Escherichia coli arginyl–tRNA synthetase observed by 19F NMR spectroscopy

G. Zhu, E. Wang, Qing-Shuo Zhang, 2003, FEBS letters.

Leucyl‐tRNA synthetase from the ancestral bacterium Aquifex aeolicus contains relics of synthetase evolution

Gilbert Eriani, G. Eriani, E. Wang, 2005, The EMBO journal.

Translational Quality Control by Bacterial Threonyl-tRNA Synthetases*

Yun Chen, E. Wang, Xiao-Long Zhou, 2016, The Journal of Biological Chemistry.

Role of tRNA amino acid-accepting end in aminoacylation and its quality control

G. Eriani, H. Lei, E. Wang, 2011, Nucleic acids research.

tRNA-dependent Pre-transfer Editing by Prokaryotic Leucyl-tRNA Synthetase*

Gilbert Eriani, En-Duo Wang, G. Eriani, 2009, The Journal of Biological Chemistry.

The CP2 Domain of Leucyl-tRNA Synthetase Is Crucial for Amino Acid Activation and Post-transfer Editing*

E. Wang, Xiao-Long Zhou, B. Zhu, 2008, Journal of Biological Chemistry.

1H, 15N chemical shift assignments of the imino groups in the base pairs of Escherichia coli tRNALeu (CAG)

G. Zhu, E. Wang, Rui Feng, 2011, Biomolecular NMR assignments.

RNA granule-clustered mitochondrial aminoacyl-tRNA synthetases form multiple complexes with the potential to fine-tune tRNA aminoacylation

E. Wang, Xin Chen, Xue-Ling Mao, 2022, Nucleic acids research.

Loss of threonyl-tRNA synthetase-like protein Tarsl2 has little impact on protein synthesis but affects mouse development

Fan Zhang, E. Wang, Z. Hei, 2023, The Journal of biological chemistry.

Human mitochondrial leucyl-tRNA synthetase with high activity produced from Escherichia coli.

E. Wang, Xiang-fu Wu, Yong-Neng Yao, 2003, Protein expression and purification.

CP1 domain in Escherichia coli leucyl-tRNA synthetase is crucial for its editing function.

Y L Wang, E. Wang, J F Chen, 2000, Biochemistry.

A T-stem slip in human mitochondrial tRNALeu(CUN) governs its charging capacity

E. Wang, Yong-Neng Yao, Ming-Wei Zhao, 2005, Nucleic acids research.

Groups on the side chain of T252 in Escherichia coli leucyl-tRNA synthetase are important for discrimination of amino acids and cell viability.

En-Duo Wang, E. Wang, Min-Gang Xu, 2004, Biochemical and biophysical research communications.

Human TRMT1 catalyzes m2G or m22G formation on tRNAs in a substrate-dependent manner

E. Wang, Ru-Juan Liu, Jing Li, 2023, Science China Life Sciences.

Recognition of tRNALeu by Aquifex aeolicus leucyl-tRNA synthetase during the aminoacylation and editing steps

G. Eriani, E. Wang, P. Yao, 2008, Nucleic acids research.

Discrimination of tRNA(Leu) isoacceptors by the mutants of Escherichia coli leucyl-tRNA synthetase in editing.

E. Wang, Xing Du, 2002, Biochemistry.

Effect of alanine-293 replacement on the activity, ATP binding, and editing of Escherichia coli leucyl-tRNA synthetase.

E. Wang, Y. Wang, J. F. Chen, 2001, Biochemistry.

Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination.

Yunqing Liu, Jianping Ding, E. Wang, 2006, The Biochemical journal.

The Overproduction of Leucyl-tRNA Synthetase in E. coli and Its Purification.

E. Wang, Tong Li, Ying-lai Wang, 1997, Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica.