M. H. Rabinowitz

发表

Discovery of the first known small-molecule inhibitors of heme-regulated eukaryotic initiation factor 2alpha (HRI) kinase.

M. Rosen, C. Woods, S. Goldberg, 2009, Bioorganic & medicinal chemistry letters.

Inhibition of hypoxia-inducible factor prolyl hydroxylase domain oxygen sensors: tricking the body into mounting orchestrated survival and repair responses.

M. H. Rabinowitz, Michael H Rabinowitz, M. Rabinowitz, 2013, Journal of medicinal chemistry.

Prolyl hydroxylase inhibition corrects functional iron deficiency and inflammation‐induced anaemia in rats

M. Rosen, T. Barrett, K. C. Kanelakis, 2015, British journal of pharmacology.

Beyond Traditional Structure-Based Drug Design: The Role of Iron Complexation, Strain, and Water in the Binding of Inhibitors for Hypoxia-Inducible Factor Prolyl Hydroxylase 2

S. Bembenek, T. Mirzadegan, M. Rosen, 2019, ACS omega.

Benzimidazole-2-pyrazole HIF Prolyl 4-Hydroxylase Inhibitors as Oral Erythropoietin Secretagogues.

S. Bembenek, T. Mirzadegan, M. Rosen, 2010, ACS medicinal chemistry letters.

Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol- 2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective HIF prolyl hydroxylase (PHD) inhibitor

S. Bembenek, T. Mirzadegan, M. Rosen, 2011 .

Pharmacological Characterization of 1-(5-Chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic Acid (JNJ-42041935), a Potent and Selective Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor

S. Bembenek, T. Mirzadegan, M. Rosen, 2011, Molecular Pharmacology.

Inhibitors of HIF Prolyl Hydroxylases

M. Rosen, T. Barrett, M. H. Rabinowitz, 2010 .

Characterization of a Robust Enzymatic Assay for Inhibitors of 2-Oxoglutarate-Dependent Hydroxylases

Jiejun Wu, M. Rosen, Y. Yang, 2009, Journal of biomolecular screening.