A. Kappas

N. Abraham, A. Kappas, M. Laniado-Schwartzman, 1995, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.

This information is current as Oxygenase-1 Inhibitor Tin Mesoporphyrin Proliferate in Response to the Heme Naive Human T Cells Are Activated and Kappas and

Jeff E. Mold, J. McCune, L. Seu, 2010 .

Naive Human T Cells Are Activated and Proliferate in Response to the Heme Oxygenase-1 Inhibitor Tin Mesoporphyrin

Jeff E. Mold, J. McCune, L. Seu, 2010, The Journal of Immunology.

Hypothalamic mechanism for cobalt protoporphyrin-induced hypophagia and weight loss: inhibition of the feeding response to NPY.

S. Chua, A. Kappas, R. Galbraith, 1992, Brain research. Molecular brain research.

Drug stimulation of -aminolevulinic acid synthetase and cytochrome P-450 in vivo in chick embryo liver.

A. Kappas, P. Gillette, C. Song, 1973, The Journal of pharmacology and experimental therapeutics.

Overexpression of human heme oxygenase-1 attenuates endothelial cell sloughing in experimental diabetes.

L. Rodella, R. Rezzani, G. Li Volti, 2004, American journal of physiology. Heart and circulatory physiology.

Increased HO-1 Levels Ameliorate Fatty Liver Development Through a Reduction of Heme and Recruitment of FGF21

N. Abraham, T. Hinds, Dong Hyun Kim, 2013, Obesity.

Up-Regulation of Heme Oxygenase Provides Vascular Protection in an Animal Model of Diabetes through Its Antioxidant and Antiapoptotic Effects

S. Shenouda, M. Goligorsky, N. Abraham, 2006, Journal of Pharmacology and Experimental Therapeutics.

HO-1 Induction Improves The Type-1 Cardiorenal Syndrome in Mice With Impaired Angiotensin II–Induced Lymphocyte Activation

N. Abraham, Larisa V. Fedorova, A. Kappas, 2013, Hypertension.

The influence of pregnancy and oral contraceptive steroids on the concentration of plasma proteins. Studies with a quantitative immunodiffusion method.

I. Merkatz, A. Kappas, P. Gillette, 1970, American journal of obstetrics and gynecology.

The Biological Significance and Physiological Role of Heme Oxygenase

N. Abraham, A. Kappas, G. Drummond, 1996 .

Solubilization and partial purification of heme oxygenase from rat liver.

A. Kappas, M. Maines, N. Ibrahim, 1977, The Journal of biological chemistry.

Studies in Endocrine Pharmacology

A. Kappas, 2010 .

Biologic actions of some natural steroids on the liver.

A. Kappas, 1968, The New England journal of medicine.

Mechanism of heme-heme oxygenase system impairment of endothelium contraction in the spontaneously hypertensive rat.

N. Abraham, A. Kappas, 2011, Hypertension.

Long-Lasting Expression of HO-1 Delays Progression of Type I Diabetes in NOD Mice

N. Abraham, S. Ikehara, A. Kappas, 2007, Cell cycle.

Negative regulation of human heme oxygenase in microvessel endothelial cells by dexamethasone.

T. Deramaudt, N. Abraham, A. Kappas, 1999, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

A heat-inducible nuclear factor that binds to the heat-shock element of the human haem oxygenase gene.

K. Mitani, S. Sassa, A. Kappas, 1991, The Biochemical journal.

Activation of heme oxygenase and heat shock protein 70 genes by stress in human hepatoma cells.

K. Mitani, S. Sassa, A. Kappas, 1990, Biochemical and biophysical research communications.

Reduction of the C2 and C4 vinyl groups of Sn-protoporphyrin to form Sn-mesoporphyrin markedly enhances the ability of the metalloporphyrin to inhibit in vivo heme catabolism.

A. Kappas, G. Drummond, M. Sardana, 1987, Archives of biochemistry and biophysics.

Dual control mechanism for heme oxygenase: tin(IV)-protoporphyrin potently inhibits enzyme activity while markedly increasing content of enzyme protein in liver.

A. Kappas, M. Sardana, 1987, Proceedings of the National Academy of Sciences of the United States of America.

The occurrence of molecular interactions among NADPH-cytochrome c reductase, heme oxygenase, and biliverdin reductase in heme degradation.

S. Sassa, A. Kappas, T. Yoshinaga, 1982, The Journal of biological chemistry.

The oxidative degradation of heme c by the microsomal heme oxygenase system.

S. Sassa, A. Kappas, T. Yoshinaga, 1982, The Journal of biological chemistry.

Purification and properties of bovine spleen heme oxygenase. Amino acid composition and sites of action of inhibitors of heme oxidation.

S. Sassa, A. Kappas, T. Yoshinaga, 1982, The Journal of biological chemistry.

Metal ion-mediated regulation of heme oxygenase induction in cultured avian liver cells.

S. Sassa, A. Kappas, M. Sardana, 1982, The Journal of biological chemistry.

Metal induction of haem oxygenase without concurrent degradation of cytochrome P-450. Protective effects of compound SKF 525A on the haem protein.

D. Rosenberg, A. Kappas, G. Drummond, 1982, The Biochemical journal.

Enzymatic oxidation of cobalt protoporphyrin IX: observations on the mechanism of heme oxygenase action.

A. Kappas, M. Maines, 1977, Biochemistry.

Comparative Effects of Heme and Metalloporphyrins on Interferon-γ-Mediated Pathways in Monocytic Cells (THP-1)

G. Werner-Felmayer, D. Fuchs, N. Abraham, 1993, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Heme Oxygenase Inhibitors Transiently Increase Serum Ferritin Concentrations without Altering Other Acute-Phase Reactants in Man

B. Angelin, A. Kappas, L. Berglund, 1999, Pharmacology.

Control of jaundice in preterm newborns by an inhibitor of bilirubin production: studies with tin-mesoporphyrin.

C. Henschke, A. Kappas, G. Drummond, 1994, Pediatrics.

Serial Review: Heme Oxygenase in Human Disease Serial Review Editor: Phyllis A. Dennery Heme oxygenase and the cardiovascular-renal system i

N. Abraham, A. Kappas, 2005 .

Biochemical properties of the heme oxygenase inhibitor, Sn-protoporphyrin. Interactions with apomyoglobin and human serum albumin.

R. Chandra, A. Kappas, E. Breslow, 1986, Journal of Biological Chemistry.

Negative Regulation of Human Heme Oxygenase in Microvessel Endothelial Cells by Dexamethasone (44443)

T. Deramaudt, N. Abraham, A. Kappas, 1999 .

Differential effect of heme oxygenase-1 in endothelial and smooth muscle cell cycle progression.

F. Traganos, G. Li Volti, N. Abraham, 2002, Biochemical and biophysical research communications.

A significant role for the heme oxygenase-1 gene in endothelial cell cycle progression.

N. Abraham, S. Ikehara, A. Kappas, 2002, Biochemical and biophysical research communications.

Protective effect of HO-1 against oxidative stress in human hepatoma cell line (HepG2) is independent of telomerase enzyme activity.

N. Abraham, A. Kappas, M. Ghattas, 2002, The international journal of biochemistry & cell biology.

Regulation of heme pathway enzymes and cellular glutathione content by metals that do not chelate with tetrapyrroles: blockade of metal effects by thiols.

A. Kappas, M. Maines, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Message amplification phenotyping of an inherited delta-aminolevulinate dehydratase deficiency in a family with acute hepatic porphyria.

S. Sassa, A. Kappas, H. Fujita, 1990, Biochemical and biophysical research communications.

Heme oxygenase induction with attenuation of experimentally induced corneal inflammation.

N. Abraham, A. Kappas, M. Laniado-Schwartzman, 1997, Biochemical pharmacology.

Hormones and the liver. The effect of estrogens, progestins, and pregnancy on hepatic function.

A. Kappas, P. Gillette, C. Song, 1969, American journal of obstetrics and gynecology.

The effects of estradiol and estriol on plasma levels of cortisol and thyroid hormone-binding globulins and on aldosterone and cortisol secretion rates in man.

A. Kappas, F. Katz, 1967, The Journal of clinical investigation.

Additive effect of erythropoietin and heme on murine hematopoietic recovery after azidothymidine treatment.

N. Abraham, A. Kappas, J. Harrison, 1993, Blood.

Injection of cobalt protoporphyrin into the medial nuclei of the hypothalamus elicits weight loss.

D. Pfaff, L. Kow, A. Kappas, 1992, The American journal of physiology.

Regulation of food intake and body weight in rats by the synthetic heme analogue cobalt protoporphyrin.

A. Kappas, R. Galbraith, 1991, The American journal of physiology.

Cobalt-protoporphyrin suppresses expression of genetic obesity in homozygous (fa/fa) Zucker rats.

A. Kappas, R. Galbraith, 1990, Pharmacology.

hepatoma cells Heme oxygenase is a positive acute-phase reactant in human Hep 3

K. Mitani, S. Sassa, A. Kappas, 2003 .

Coexpression of erythropoietin and heme oxygenase genes in Hep3B cells

S. Shibahara, N. Abraham, A. Kappas, 1993, Hepatology.

Targeting of heme oxygenase inhibitors to the spleen markedly increases their ability to diminish bilirubin production.

A. Kappas, S. Landaw, G. Drummond, 1989, Pediatrics.

The influence of steroid hormone metabolites on the in vitro development of erythroid colonies derived from human bone marrow

S. Sassa, A. Kappas, A. Urabe, 1979, The Journal of experimental medicine.

Diminished Heme Oxygenase Potentiates Cell Death: Pyrrolidinedithiocarbamate Mediates Oxidative Stress

N. Abraham, A. Kappas, L. Malaguarnera, 2003, Experimental biology and medicine.

Regulation of cyclooxygenase by the heme-heme oxygenase system in microvessel endothelial cells.

N. Abraham, M. Schwartzman, A. Kappas, 2002, The Journal of pharmacology and experimental therapeutics.

Heme biosynthesis and drug metabolism in mice with hereditary hemolytic anemia. Heme oxygenase induction as an adaptive response for maintaining cytochrome P-450 in chronic hemolysis.

S. Sassa, A. Kappas, A. Alvares, 1979, The Journal of biological chemistry.

5′‐NUCLEOTIDASE OF PLASMA MEMBRANES OF THE RAT LIVER: STUDIES ON SUBCELLULAR DISTRIBUTION

A. Kappas, C. Song, O. Bodansky, 1969, Annals of the New York Academy of Sciences.

Pharmacological and Clinical Aspects of Heme Oxygenase

N. Abraham, A. Kappas, 2008, Pharmacological Reviews.

Regulation of human heme oxygenase in endothelial cells by using sense and antisense retroviral constructs

N. Abraham, A. Kappas, S. Quan, 2001, Proceedings of the National Academy of Sciences of the United States of America.

A single dose of Sn-mesoporphyrin prevents development of severe hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient newborns.

A. Kappas, G. Drummond, T. Valaes, 2001, Pediatrics.

Inhibition of human immunodeficiency virus-1 reverse transcriptase by heme and synthetic heme analogs.

N. Abraham, A. Kappas, R. Staudinger, 1996, Proceedings of the Association of American Physicians.

Differential heme oxygenase induction by stannous and stannic ions in the heart

N. Abraham, A. Kappas, R. Levere, 1995, Journal of cellular biochemistry.

Long-term bone marrow stromal and hemopoietic toxicity to AZT: protective role of heme and IL-1.

N. Abraham, A. Kappas, R. Staudinger, 1993, Experimental hematology.

Suppression of bilirubin production in the Crigler-Najjar type I syndrome: studies with the heme oxygenase inhibitor tin-mesoporphyrin.

A. Kappas, G. Drummond, R. Galbraith, 1992, Pediatrics.

Heme inhibits human immunodeficiency virus 1 replication in cell cultures and enhances the antiviral effect of zidovudine.

N. Abraham, A. Kappas, G. Wormser, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Heat shock induction of heme oxygenase mRNA in human Hep 3B hepatoma cells.

K. Mitani, S. Sassa, A. Kappas, 1989, Biochemical and biophysical research communications.

Pharmacokinetics of tin‐mesoporphyrin in man and the effects of tin‐chelated porphyrins on hyperexcretion of heme pathway precursors in patients with acute inducible porphyria

A. Kappas, R. Galbraith, 1989, Hepatology.

Control of Heme Oxygenase and Plasma Levels of Bilirubin by a Synthetic Heme Analogue, Tin‐Protoporphyrin

K. Anderson, A. Kappas, G. Drummond, 1984, Hepatology.

Thyroid hormone regulation of heme oxidation in the liver.

A. Kappas, G. Drummond, T. Smith, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Differential responses to inducers of delta-aminolaevulinate synthase and haem oxygenase during pregnancy.

S. Sassa, A. Kappas, M. Sardana, 1981, The Biochemical journal.

Adrenalectomy enhances the induction of heme oxygenase and the degradation of cytochrome P-450 in liver.

S. Sassa, A. Kappas, M. Sardana, 1980, The Journal of biological chemistry.

Pyrogenic and inflammatory properties of certain bile acids in man.

R. Palmer, A. Kappas, P. Glickman, 1962, The Journal of clinical investigation.

The pyrogenic effect of etiocholanolone.

A. Kappas, D. Fukushima, T. Gallagher, 1957, The Journal of clinical endocrinology and metabolism.

Stimulators and inhibitors of hepatic porphyrin formation in human sera.

R. Winchester, I. Merkatz, S. Sassa, 1974, The Journal of clinical investigation.

Synergistic effect of heme and IL‐1 on hematopoietic stromal regeneration after radiation

N. Abraham, A. Kappas, R. Levere, 1993, American journal of hematology.

Porphyrin-Heme Pathway: Regulation by Intermediates in Bile Acid Synthesis

A. Kappas, N. Javitt, A. Rifkind, 1973, Science.

Hereditary tyrosinemia and the heme biosynthetic pathway. Profound inhibition of delta-aminolevulinic acid dehydratase activity by succinylacetone.

S. Sassa, A. Kappas, 1983, The Journal of clinical investigation.

PROFOUND INHIBITION OF 8-AMINOLEVULINIC ACID DEHYDRATASE ACTIVITY BY SUCCINYLACETONE

S. Sassa, A. Kappas, 1983 .

Zinc porphyrins: potent inhibitors of hematopoieses in animal and human bone marrow.

N. Abraham, A. Kappas, G. Drummond, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Disposition of tin‐protoporphyrin and suppression of hyperbilirubinemia in humans

K. Anderson, A. Kappas, G. Drummond, 1986, Clinical pharmacology and therapeutics.

Prolonged induction of hepatic haem oxygenase and decreases in cytochrome P-450 content by organotin compounds.

D. Rosenberg, A. Kappas, G. Drummond, 1980, The Biochemical journal.

Studies in steroid metabolism. XXVI. Steroid isolation studies in human leukemia.

A. Kappas, T. Gallagher, K. Dobriner, 1954, The Journal of clinical investigation.

Studies on the mechanism of Sn-protoporphyrin suppression of hyperbilirubinemia. Inhibition of heme oxidation and bilirubin production.

K. Anderson, A. Kappas, G. Drummond, 1985, The Journal of clinical investigation.

Tissue distribution and disposition of tin-protoporphyrin, a potent competitive inhibitor of heme oxygenase.

K. Anderson, A. Kappas, G. Drummond, 1984, The Journal of pharmacology and experimental therapeutics.

Alkaptonuria and Ochronotic Arthropathy

A. Kappas, L. B. Sorensen, M. N. Mueller, 1965 .

Porphyrin-heme biosynthesis in organotypic cultures of mouse dorsal root ganglia. Effects of heme and lead on porphyrin synthesis and peripheral myelin.

W. Whetsell, S. Sassa, A. Kappas, 1984, The Journal of clinical investigation.

Coproporphyrin I and 3 excretion in bile and urine.

N. Kaplowitz, A. Kappas, N. Javitt, 1972, The Journal of clinical investigation.

Genetic, metabolic, and biochemical aspects of the porphyrias.

S. Sassa, A. Kappas, S Sassa, 1981, Advances in human genetics.

Influence of estradiol and estriol on urinary excretion of hydroxyproline in man.

A. Kappas, F. Katz, 1968, The Journal of laboratory and clinical medicine.

Human skin aryl hydrocarbon hydroxylase. Induction by coal tar.

D. Bickers, A. Kappas, 1978, The Journal of clinical investigation.

7,8-Benzoflavone stimulates the metabolic activation of aflatoxin B1 to mutagens by human liver.

A. Kappas, J. Fortner, M. Buening, 1978, Biochemical and biophysical research communications.

Cytochrome P-450C-M/F, a new constitutive form of microsomal cytochrome P-450 in male and female rat liver with estrogen 2- and 16 alpha-hydroxylase activity.

O. Sugita, S. Sassa, A. Kappas, 1988, Biochemistry.

Effects of Steroid Sex Hormones on Immunological Phenomena

A. Kappas, I. Roitt, H. Jones, 1963, Nature.

THE INFLUENCE OF POSTNATAL DEVELOPMENT ON DRUG-INDUCED HEPATIC PORPHYRIA AND THE SYNTHESIS OF CYTOCHROME P-450

H. Moses, A. Kappas, N. Gelb, 1971, The Journal of experimental medicine.

Polychlorinated biphenyls: a new type of inducer of cytochrome P-448 in the liver.

D. Bickers, A. Kappas, A. Alvares, 1973, Proceedings of the National Academy of Sciences of the United States of America.

Prevention of cyclical attacks of acute intermittent porphyria with a long-acting agonist of luteinizing hormone-releasing hormone.

K. Anderson, C. Bardin, S. Sassa, 1984, The New England journal of medicine.

Studies in porphyria. IV. Expression of the gene defect of acute intermittent porphyria in cultured human skin fibroblasts and amniotic cells: prenatal diagnosis of the porphyric trait

S. Sassa, A. Kappas, R. Levere, 1975, The Journal of experimental medicine.

Assays for porphyrins, delta-aminolevulinic-acid dehydratase, and porphyrinogen synthetase in microliter samples of whole blood: applications to metabolic defects involving the heme pathway.

S. Granick, S. Sassa, A. Kappas, 1972, Proceedings of the National Academy of Sciences of the United States of America.

A fluorometric method for measuring ethoxycoumarin O-deethylase activity by reversed-phase high performance liquid chromatography.

D. Rosenberg, A. Kappas, H. Roque, 1990, Analytical biochemistry.

Lack of effect of pregnancy or hematin therapy on erythrocyte porphobilinogen deaminase activity in acute intermittent porphyria.

S. Sassa, A. Kappas, 1989, The New England journal of medicine.

Purification and properties of uroporphyrinogen decarboxylase from human erythrocytes. A single enzyme catalyzing the four sequential decarboxylations of uroporphyrinogens I and III.

H. de Verneuil, S. Sassa, A. Kappas, 1983, The Journal of biological chemistry.

Studies in porphyria; v. Drug oxidation rates in hereditary hepatic porphyria

K. Anderson, S. Sassa, A. Kappas, 1976, Clinical pharmacology and therapeutics.

Immunochemical study of uroporphyrinogen decarboxylase in a patient with mild hepatoerythropoietic porphyria.

S. Sassa, A. Kappas, H. Fujita, 1987, The Journal of clinical investigation.

Increased erythrocyte uroporphyrinogen-l-synthetase, delta-aminolevulinic acid dehydratase and protoporphyrin in hemolytic anemias.

C. Peterson, K. Anderson, S. Sassa, 1977, The American journal of medicine.

A microassay for uroporphyrinogen I synthase, one of three abnormal enzyme activities in acute intermittent porphyria, and its application to the study of the genetics of this disease.

D. Bickers, S. Granick, S. Sassa, 1974, Proceedings of the National Academy of Sciences of the United States of America.

The induction of heme oxidation in various tissues by trace metals: evidence for the catabolism of endogenous heme by hepatic heme oxygenase.

A. Kappas, M. Maines, 1976, Annals of clinical research.

Biochemical and Clinical Aspects of The Porphyrias1

A. Kappas, R. Levere, 1969 .

Studies in porphyria: functional evidence for a partial deficiency of ferrochelatase activity in mitogen-stimulated lymphocytes from patients with erythropoietic protoporphyria.

K. Anderson, M. Poh-Fitzpatrick, S. Sassa, 1982, The Journal of clinical investigation.

Studies on porphyrin-heme biosynthesis in organotypic cultures of chick dorsal root ganglia. II. The effect of lead.

W. Whetsell, S. Sassa, A. Kappas, 1979, Environmental research.

Studies in porphyria. VIII. Relationship of the 5 alpha-reductive metabolism of steroid hormones to clinical expression of the genetic defect in acute intermittent porphyria.

K. Anderson, S. Sassa, A. Kappas, 1979, The American journal of medicine.

Expression of the Gene Defects of Acute Intermittent Porphyria (AIP) and Erythropoietic Protoporphyria (EPP) in Mitogen-Stimulated Lymphocytes

S. Sassa, A. Kappas, G. Zalar, 1978 .

Studies in porphyria. VII. Induction of uroporphyrinogen-I synthase and expression of the gene defect of acute intermittent porphyria in mitogen-stimulated human lymphocytes.

S. Sassa, A. Kappas, G. Zalar, 1978, The Journal of clinical investigation.

Induction of a deficiency of steroid delta 4-5 alpha-reductase activity in liver by a porphyrinogenic drug.

D. Bickers, A. Kappas, H. Bradlow, 1977, The Journal of clinical investigation.

Prenatal diagnosis of acute intermittent porphyria.

S. Sassa, A. Kappas, 1976, The New England journal of medicine.

Induction of a Deficiency of Steroid A4-5a-Reductase Activity in Liver by a Porphyrinogenic Drug

D. Bickers, A. Kappas, H. Bradlow, 2022 .

EFFECT OF LEAD AND GENETIC FACTORS ON HEME BIOSYNTHESIS IN THE HUMAN RED CELL *

S. Granick, S. Sassa, A. Kappas, 1975, Annals of the New York Academy of Sciences.

Studies in porphyria. II. Evidence for a deficiency of steroid delta-4-5-alpha-reductase activity in acute intermittent porphyria.

A. Kappas, H. Bradlow, P. Gillette, 1973 .

Studies on the inheritance of human erythrocyte delta-aminolevulinate dehydratase and uroporphyrinogen synthetase.

D. Bickers, S. Granick, S. Sassa, 1973, Enzyme.

A defect of steroid hormone metabolism in acute intermittent porphyria.

A. Kappas, H. Bradlow, P. Gillette, 1972, Federation proceedings.

Recent advances in porphyrin metabolism.

A. Kappas, J. Pindyck, R. Levere, 1971, CRC critical reviews in clinical laboratory sciences.

Induction of Uroporphyrinogen-I Synthase Activity in Mitogen-Stimulated Lymphocytes: Deficient Induction in Acute Intermittent Porphyria Cells

S. Sassa, A. Kappas, G. Zalar, 1978 .

IV.Expression ofthe Gene DefectofAcute IntermittentPorphyria in Cultured Human Skin Fibroblastsand Amniotic Cells:Prenatal Diagnosis ofthe Porphyric Trait*

A. Kappas, R. Levere, S. S. G. Solish, 1975 .

Sn-protoporphyrin suppresses chemically induced experimental hepatic porphyria. Potential clinical implications.

A. Kappas, G. Drummond, R. Galbraith, 1985, The Journal of clinical investigation.

Plumbism from airborne lead in a firing range. An unusual exposure to a toxic heavy metal.

K. Anderson, S. Sassa, A. Kappas, 1977, The American journal of medicine.

STUDIES IN PORPHYRIA

D. Bickers, A. Kappas, L. Harber, 1972, The Journal of experimental medicine.

I. A DEFECT IN THE REDUCTIVE TRANSFORMATION OF NATURAL STEROID HORMONES IN THE HEREDITARY LIVER DISEASE, ACUTE INTERMITTENT PORPtIYRIA*

A. Kappas, H. Bradlow, P. Gillette, 1972 .

ABNORMAL STEROID HORMONE METABOLISM IN THE GENETIC LIVER DISEASE ACUTE INTERMITTENT PORPHYRIA *

A. Kappas, H. Bradlow, P. Gillette, 1971, Annals of the New York Academy of Sciences.

δ-Aminolevulinate Synthetase of the Chick Embryo Liver: The Effect of Natural and Synthetic Sex Steroids on its Activity

A. Kappas, P. Gillette, A. Rifkind, 1969 .

Sex hormones the gastrointestinal tract and the liver: introductory comments.

A. Kappas, Chull S. Song, 1969 .

Steroid induction of porphyrin synthesis in liver cell culture. II. The effects of heme, uridine diphosphate glucuronic acid, and inhibitors of nucleic acid and protein synthesis on the induction process.

S. Granick, A. Kappas, 1968, The Journal of biological chemistry.

Steroid induction of porphyrin synthesis in liver cell culture. I. Structural basis and possible physiological role in the control of heme formation.

S. Granick, A. Kappas, 1967, The Journal of biological chemistry.

A comparative study of heme degradation by NADPH-cytochrome c reductase alone and by the complete heme oxygenase system. Distinctive aspects of heme degradation by NADPH-cytochrome c reductase.

S. Sassa, A. Kappas, T. Yoshinaga, 1982, The Journal of biological chemistry.

Proof that Sn-protoporphyrin inhibits the enzymatic catabolism of heme in vivo. Suppression of 14CO generation from radiolabeled endogenous and exogenous heme sources

S. Sassa, A. Kappas, S. Landaw, 1987, The Journal of experimental medicine.

Stimulatory effect of brussels sprouts and cabbage on human drug metabolism

A. Conney, K. Anderson, A. Kappas, 1979, Clinical pharmacology and therapeutics.

Induction of aminolevulinate synthase and porphyrins in cultured liver cells maintained in chemically defined medium. Permissive effects of hormones on induction process.

S. Sassa, A. Kappas, 1977, The Journal of biological chemistry.

Partial purification of cytochrome P450 from rat brain and demonstration of estradiol hydroxylation.

O. Sugita, S. Sassa, A. Kappas, 1987, Biochemical and biophysical research communications.

Differences in inducibility of cutaneous and hepatic drug metabolizing enzymes and cytochrome P-450 by polychlorinated biphenyls and 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT).

D. Bickers, A. Kappas, A. Alvares, 1974, The Journal of pharmacology and experimental therapeutics.

Inhibition of chemical induction of porphyrin synthesis in chick embryo liver cells by partially purified human chorionic gonadotropin.

R. Canfield, A. Kappas, A. Rifkind, 1976, Biochemical and biophysical research communications.

The thermogenic effect and metabolic fate of etiocholanolone in man.

A. Kappas, D. Fukushima, T. Gallagher, 1958, The Journal of clinical endocrinology and metabolism.

Growth‐promoting effects of iron‐ and cobalt‐protoporphyrins on cultured embryonic cells

S. Sassa, A. Kappas, C. Verger, 1983, Journal of cellular physiology.

Studies in steroid metabolism. XXXIV. Identification and characterization of 3-beta-hydroxy-delta 9(11)-androstene-17-one and 3beta, 11beta-dihydroxyandrostane-17-one from human urine.

A. Kappas, T. Gallagher, I. Salamon, 1954, The Journal of biological chemistry.

Stimulation of mammalian erythropoiesis by 5beta-H steroid metabolites.

A. Kappas, A. S. Gordon, E. Zanjani, 1970, Proceedings of the National Academy of Sciences of the United States of America.

Sequential induction of enzymes in the heme biosynthetic pathway during erythroid differentiation.

S. Granick, S. Sassa, A. Kappas, 1975, Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society.

Inhibitory effect of a‐amanitin on the induction of δ‐aminolevulinate synthetase in chick embryo liver

A. Kappas, G. Incefy, 1971, FEBS letters.

The Biological Basis of Cancer

V. Cogliano, G. Voutsinas, A. Kappas, 1999 .

Inhibition of δ-aminolevulinate synthetase induction by α-amanitin in avian liver cell cultures

A. Kappas, A. Rifkind, G. Incefy, 1974 .

THE INDUCTION OF delta-AMINOLEVULINIC ACID SYNTHETASE in vivo IN CHICK EMBRYO LIVER BY NATURAL STEROIDS.

S. Granick, A. Kappas, C. Song, 1968, Proceedings of the National Academy of Sciences of the United States of America.

Downregulation of PGC-1α Prevents the Beneficial Effect of EET-Heme Oxygenase-1 on Mitochondrial Integrity and Associated Metabolic Function in Obese Mice

J. Falck, N. Abraham, L. Vanella, 2016, Journal of nutrition and metabolism.

Crigler-Najjar syndrome, 1952-2000: learning from parents and patients about a very rare disease and using the internet to recruit patients for studies.

A. Kappas, J. Lucey, G. Suresh, 2000, Pediatrics.

Small Interfering RNA Targeting Heme Oxygenase-1 Enhances Ischemia-Reperfusion-induced Lung Apoptosis*

Patty J. Lee, N. Abraham, A. Kappas, 2004, Journal of Biological Chemistry.

The biological properties of etiocholanolone. Combined clinical staff conference at the National Institutes of Health.

S. Perry, S. Wolff, A. Kappas, 1967, Annals of internal medicine.

Chemoprevention of severe neonatal hyperbilirubinemia.

A. Kappas, G. Drummond, 2004, Seminars in perinatology.

Stimulation of hemoglobin synthesis in chick blastoderms by certain 5beta androstane and 5beta pregnane steroids.

S. Granick, A. Kappas, R. Levere, 1967, Proceedings of the National Academy of Sciences of the United States of America.

Steroid control of porphyrin and heme biosynthesis: a new biological function of steroid hormone metabolites.

S. Granick, A. Kappas, 1967, Proceedings of the National Academy of Sciences of the United States of America.

Steroid effects on hepatic function: recent observations.

A. Kappas, J. Kottra, 1967, Annual review of medicine.

Steroid induction of porphyrin synthesis in liver cell culture.

S. Granick, A. Kappas, S. Granick, 1967, Transactions of the Association of American Physicians.

Chapter 1 – Thermogenic Properties of Steroids

R. Palmer, A. Kappas, 1965 .

Selected aspects of steroid pharmacology.

R. Palmer, A. Kappas, 1963, Pharmacological reviews.

Fever-Producing Action of Steroids

R. Palmer, A. Kappas, 1963 .

Steroid pyrogen studies in laboratory and domestic animals.

R. Palmer, A. Kappas, B. Ratkovits, 1961, Journal of applied physiology.

Letters to the Editor: SPECIES SPECIFICITY OF STEROID-INDUCED FEVER

A. Kappas, B. Ratkovits, 1960 .

Steroid fever studies: physiological differences between bacterial pyrogens and endogenous steroid pyrogens of man.

R. Palmer, A. Kappas, P. Glickman, 1960, Transactions of the Association of American Physicians.

Nutrition-endocrine interactions: induction of reciprocal changes in the delta 4-5 alpha-reduction of testosterone and the cytochrome P-450-dependent oxidation of estradiol by dietary macronutrients in man.

A. Conney, K. Anderson, A. Kappas, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Polychlorinated biphenyls: comparative effects of high and low chlorine containing Aroclors on hepatic mixed function oxidase.

D. Bickers, A. Kappas, L. Harber, 1972, Research communications in chemical pathology and pharmacology.

Steroid induction of delta-aminolevulinic acid synthase and porphyrins in liver. Structure-activity studies and the permissive effects of hormones on the induction process.

S. Sassa, A. Kappas, H. Bradlow, 1979, The Journal of biological chemistry.

ADRENOCORTICAL HYPERFUNCTION IN "IDIOPATHIC" HIRSUTISM AND THE STEIN-LEVENTHAL SYNDROME'

A. Kappas, M. Lipsett, T. Gallagher, 1958 .

The inhibitory effect of coproporphyrins on amino acid uptake into proteins by porphyric liver cells

A. Kappas, G. Incefy, 1972, FEBS letters.

Heme Oxygenase Gene Targeting to Adipocytes Attenuates Adiposity and Vascular Dysfunction in Mice Fed a High-Fat Diet

L. Rodella, N. Abraham, L. Vanella, 2012, Hypertension.

Heme oxygenase and the cardiovascular-renal system.

N. Abraham, A. Kappas, 2005, Free radical biology & medicine.

The absence of significant biliary excretion of antipyrine or its metabolites in humans

A. Kappas, P. Wissel, 1987, Clinical pharmacology and therapeutics.

How the liver metabolizes foreign substances.

A. Kappas, A. Alvares, 1975, Scientific American.

THE EFFECT OF ENVIRONMENTAL LIGHT EXPOSURE ON DRUG‐INDUCED PORPHYRIA IN THE RAT

D. Bickers, A. Kappas, L. Harber, 1976, Photochemistry and photobiology.

Erythrocyte uroporphyrinogen decarboxylase activity in porphyria cutanea tarda: a study of 40 consecutive patients.

S. Sassa, A. Kappas, L. Harber, 1989, The Journal of investigative dermatology.

Porphyria cutanea tarda associated with the acquired immune deficiency syndrome

K. Anderson, S. Sassa, A. Kappas, 1987, American journal of hematology.

The metabolism of aminopyrine in chick embryo hepatic cell culture: effects of competitive substrates and carbon monoxide.

A. Kappas, A. Poland, 1971, Molecular pharmacology.

A gonadotropin releasing hormone analogue prevents cyclical attacks of porphyria.

C. Bardin, A. Kappas, K. Anderson, 1990, Archives of internal medicine.

The molecular defect of ferrochelatase in a patient with erythropoietic protoporphyria.

S. Sassa, A. Kappas, S. Taketani, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Studies in porphyria. I. A defect in the reductive transformation of natural steroid hormones in the hereditary liver disease, acute intermittent porphyria.

A. Kappas, H. Bradlow, P. Gillette, 1972 .

Hereditary hepatic porphyria due to homozygous δ‐aminolevulinic acid dehydratase deficiency: studies in lymphocytes and erythrocytes

S. Sassa, A. Kappas, H. Fujita, 1991, European journal of clinical investigation.

Purification and properties of human erythrocyte uroporphyrinogen decarboxylase: immunological demonstration of the enzyme defect in porphyria cutanea tarda.

K. Anderson, H. de Verneuil, S. Sassa, 1983, Transactions of the Association of American Physicians.

Pharmacologic Effects of the Red Blood Cell Substitutes Cross-Linked and Non-Cross-Linked Hemoglobins on Hematopoiesis in Rabbits

N. Abraham, A. Kappas, G. Drummond, 1999, Pharmacology.

Human heme oxygenase: Cell cycle‐dependent expression and DNA microarray identification of multiple gene responses after transduction of endothelial cells

N. Abraham, A. Kappas, G. Scapagnini, 2003, Journal of cellular biochemistry.

Human Heme Oxygenase-1 Gene Transfer Lowers Blood Pressure and Promotes Growth in Spontaneously Hypertensive Rats

N. Abraham, M. Schwartzman, A. Kappas, 2001, Hypertension.

Influence of phenobarbital on the metabolism and analgesic effect of methadone in rats.

A. Kappas, A. Alvares, 1972, The Journal of laboratory and clinical medicine.

The effect of progesterone on activities of δ-aminolevulinic acid synthetase and δ-aminolevulinic acid dehydratase in estrogen-primed avian oviduct☆

A. Kappas, L. Miller, 1974 .

Interleukin-6 down regulates the expression of transcripts encoding cytochrome P450 IA1, IA2 and IIIA3 in human hepatoma cells.

S. Sassa, A. Kappas, Y. Fukuda, 1992, Biochemical and biophysical research communications.

Heme oxygenase is a positive acute-phase reactant in human Hep3B hepatoma cells.

K. Mitani, S. Sassa, A. Kappas, 1992, Blood.

Tin-protoporphyrin suppression of hyperbilirubinemia in mutant mice with severe hemolytic anemia.

S. Sassa, A. Kappas, G. Drummond, 1983, Blood.

Heme binding to murine erythroleukemia cells. Evidence for a heme receptor.

S. Sassa, A. Kappas, R. Galbraith, 1985, The Journal of biological chemistry.

Induction of haem synthesis in Hep G2 human hepatoma cells by dimethyl sulphoxide. A transcriptionally activated event.

S. Sassa, A. Kappas, R. Galbraith, 1986, The Biochemical journal.

delta-Aminolaevulinate synthase in human HepG2 hepatoma cells. Repression by haemin and induction by chemicals.

S. Sassa, A. Kappas, F. Iwasa, 1989, The Biochemical journal.

Sideroblastic anaemia associated with lincomycin therapy.

A. Kappas, E. Tsianos, G. Kokkini, 1983, Postgraduate medical journal.

Studies in steroid metabolism. XXVIII. The alpha-ketosteroid excretion pattern in normal females and the response to ACTH.

A. Kappas, T. Gallagher, 1955, The Journal of clinical investigation.

Studies in steroid metabolism. XXVII. A comparison of the steroid response to ACTH and cortisone in normal young men.

A. Kappas, T. Gallagher, K. Dobriner, 1955, The Journal of clinical investigation.

Hereditary tyrosinemia is an inborn error of tyrosine metabolism due to an inherited deficiency of fumarylacetoacetate hydrolase activity transmitted in an autosomal recessive fashion (1). This disease is characterized by multiple renal tubular defects accompanied with aminoaciduria and proteinuria,

S. Sassa, A. Kappas, S. Manabe, 2003 .

Hereditary tyrosinemia. Formation of succinylacetone-amino acid adducts

S. Sassa, A. Kappas, S. Manabe, 1985, The Journal of experimental medicine.

Interdiction of the diabetic state in NOD mice by sustained induction of heme oxygenase: possible role of carbon monoxide and bilirubin.

N. Abraham, S. Ikehara, A. Kappas, 2007, Antioxidants & redox signaling.

Influence of invasiveness, hormones, and amphenone on steroids in adrenal carcinoma.

H. Spencer, A. Kappas, T. Gallagher, 1956, Science.

A study of "idiopathic" hirsutism; a transitional adrenal abnormality.

A. Kappas, T. Gallagher, O. Pearson, 1956, The Journal of clinical endocrinology and metabolism.

Hormonal regulation of heme oxygenase induction in avian hepatocyte culture.

S. Sassa, A. Kappas, M. Sardana, 1985, Biochemical pharmacology.

EVIDENCE FOR A DEFICIENCY OF STEROID A4-Sa-REDUCTASE ACTIVITY IN ACUTE INTERMITTENT PORPHYRIA* BY H. LEON BRADLOW,

A. Kappas, H. Bradlow, P. Gillette, 2003 .

STUDIES IN PORPHYRIA

A. Kappas, H. Bradlow, P. Gillette, 1973, The Journal of experimental medicine.

Study of the genetic and extragenetic determinants of alpha-ketosteroid production in man.

A. Kappas, T. Gallagher, 1960, The Journal of clinical investigation.

Adrenocortical hyperfunction in idiopathic hirsutism and the Stein-Leventhal syndrome.

A. Kappas, M. Lipsett, T. Gallagher, 1958, The Journal of clinical investigation.

Selenium regulation of hepatic heme metabolism: induction of delta-aminolevulinate synthase and heme oxygenase.

A. Kappas, M. Maines, 1976, Proceedings of the National Academy of Sciences of the United States of America.

Direct comparison of Sn-mesoporphyrin, an inhibitor of bilirubin production, and phototherapy in controlling hyperbilirubinemia in term and near-term newborns.

C. Henschke, A. Kappas, G. Drummond, 1995, Pediatrics.

Control of Severe Hyperbilirubinemia in Full-term Newborns With the Inhibitor of Bilirubin Production Sn-Mesoporphyrin

A. Kappas, G. Drummond, J. Martínez, 1999, Pediatrics.

Variability in Human Drug Metabolism

A. Conney, K. Anderson, A. Kappas, 1980 .

Nutrition and chemical biotransformations in man

A. Conney, K. Anderson, A. Kappas, 1977, Clinical pharmacology and therapeutics.

Oxidative drug metabolism and inducibility by phenobarbital in sickle cell anemia

A. Kappas, K. Anderson, A. Alvares, 1977, Clinical pharmacology and therapeutics.

Inducibility of benzo [α] pyrene hydroxylase in human skin by polycyclic hydrocarbons

A. Conney, A. Kappas, W. Levin, 1973, Clinical pharmacology and therapeutics.

Diet-hormone interactions: protein/carbohydrate ratio alters reciprocally the plasma levels of testosterone and cortisol and their respective binding globulins in man.

K. Anderson, W. Rosner, M. New, 1987, Life sciences.

Biosynthesis of δ-aminolevulinic acid and porphobilinogen in the domestic fowl (Gallus domesticus)

A. Kappas, L. Miller, E. Stevens, 1974 .

Volar perilunar dislocation. A case report.

A. Kappas, J. Pournaras, 1979, The Journal of bone and joint surgery. American volume.

The occurrence of substances in human plasma capable of inducing the enzyme delta-aminolevulinate synthetase in liver cells.

S. Granick, S. Sassa, A. Kappas, 1969, Proceedings of the National Academy of Sciences of the United States of America.

EXPERIMENTAL HEPATIC PORPHYRIA: STUDIES WITH STEROIDS OF PHYSIOLOGICAL ORIGIN IN MAN

S. Granick, A. Kappas, 1968 .

The occurrence of substances in human serum which can regulate porphyrin synthesis in liver cells.

A. Kappas, A. Rifkind, 1971, Transactions of the American Clinical and Climatological Association.

Induction of Hepatic Heme Oxygenase by Metals1

A. Kappas, M. Maines, 1976 .

Enzymatic defect in a child with hereditary hepatic porphyria due to homozygous delta-aminolevulinic acid dehydratase deficiency: immunochemical studies.

S. Sassa, A. Kappas, H. Fujita, 1987, Pediatrics.

Succinylacetone inhibits delta-aminolevulinate dehydratase and potentiates the drug and steroid induction of delta-aminolevulinate synthase in liver.

S. Sassa, A. Kappas, 1982, Transactions of the Association of American Physicians.

Lead poisoning in an art conservator.

K. Anderson, S. Sassa, A. Kappas, 1982, JAMA.

Adenovirus-mediated heme oxygenase-1 gene transfer into rabbit ocular tissues.

N. Abraham, M. Schwartzman, A. Kappas, 1995, Investigative ophthalmology & visual science.

Steroid fever.

R. Palmer, A. Kappas, P. Glickman, 1961, The American journal of medicine.

Fever-producing steroids of endogenous origin in man.

A. Kappas, P. Glickman, W. Soybel, 1960, Archives of internal medicine.

The degradative effects of porphyrins and heme compounds on components of the microsomal mixed function oxidase system.

A. Kappas, M. Maines, 1975, The Journal of biological chemistry.

Apo A1 Mimetic Rescues the Diabetic Phenotype of HO-2 Knockout Mice via an Increase in HO-1 Adiponectin and LKBI Signaling Pathway

N. Abraham, A. Kappas, N. Puri, 2012, International journal of hypertension.

Intracerebroventricular administration of cobalt protoporphyrin elicits prolonged weight reduction in rats.

A. Kappas, R. Galbraith, 1991, The American journal of physiology.

Cobalt protoporphyrin regulates body weight in beagle dogs: induction of weight loss in normal animals of stable adult weight.

A. Kappas, R. Galbraith, 1991, Pharmacology.

Regulation of food intake and body weight by cobalt porphyrins in animals.

A. Kappas, R. Galbraith, A. Kappas, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Comparative Pharmacology of Zinc Mesoporphyrin and Tin Mesoporphyrin: Toxic Actions of Zinc Mesoporphyrin on Hematopoiesis and Progenitor Cell Mobilization

N. Abraham, A. Kappas, G. Drummond, 1998, Pharmacology.

Enzyme induction in the liver.

A. Kappas, C. Song, 1968, Gastroenterology.

Tissue distribution of synthetic heme analogues: studies with tin, chromium, and zinc mesoporphyrins.

A. Kappas, G. Drummond, E. Bundock, 1996, Pharmacology.

Sn-mesoporphyrin Suppression of Hyperbilirubinemia in EHBR/Eis Rats, an Animal Model of Dubin-Johnson Syndrome

A. Kappas, G. Drummond, 1998, Pharmacology.

Control of bilirubin production by synthetic heme analogs: pharmacologic and toxicologic considerations.

A. Kappas, G. Drummond, T. Valaes, 1996, Journal of perinatology : official journal of the California Perinatal Association.

Relationship of suppression of the androgenic axis by cobalt-protoporphyrin to its effects on weight loss and hepatic heme oxygenase induction.

A. Kappas, L. Krey, G. Drummond, 1987, Pharmacology.

The liver excretes large amounts of heme into bile when heme oxygenase is inhibited competitively by Sn-protoporphyrin.

K. Anderson, S. Sassa, A. Kappas, 1985, Proceedings of the National Academy of Sciences of the United States of America.

The regulation of porphyrin and heme synthesis.

S. Granick, A. Kappas, R. Levere, 1968, Seminars in hematology.

Estrogen Pharmacology: III. Effect of Estradiol on Plasm Disappearance Rate of Sulfobromophthalein in Man

A. Kappas, L. L. Kottra, 1966 .

A method for interdicting the development of severe jaundice in newborns by inhibiting the production of bilirubin.

A. Kappas, 2004, Pediatrics.

Sn‐protoporphyrin lowers serum bilirubin levels, decreases biliary bilirubin output, enhances biliary heme excretion and potently inhibits hepatic heme oxygenase activity in normal human subjects

B. Angelin, A. Kappas, L. Berglund, 1988, Hepatology.

Photophysical properties of Sn-porphyrins: potential clinical implications.

A. Kappas, D. Mauzerall, J. Delaney, 1988, Pediatrics.

Intestinal heme oxygenase inhibition and increased biliary iron excretion by metalloporphyrins.

D. Rosenberg, A. Kappas, G. Drummond, 1992, Gastroenterology.

Selective Increase in Human Heme Oxygenase-1 Gene Expression Attenuates Development of Hypertension and Increases Body Growth in Spontaneously Hypertensive Rats

S. Shenouda, N. Abraham, A. Kappas, 2001 .

Tin-mesoporphyrin inhibits heme oxygenase activity and heme-iron absorption in the intestine.

A. Kappas, G. Drummond, G. Drummond, 1993, Pharmacology.

Nutrient regulation of chemical metabolism in humans.

A. Conney, K. Anderson, A. Kappas, 1985, Federation proceedings.

A correlation between the serum protein-bound iodine and the radioiodine conversion ratio in various thyroid states.

A. Kappas, M. C. Moore, G. Sheline, 1951, The Journal of clinical endocrinology and metabolism.

Estrogen Pharmacology. II. Suppression of Experimental Immune Polyarthritis

A. Kappas, M. N. Mueller, 1964, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Immunochemical detection of cytochrome P450C-M/F and NADPH-cytochrome P450 reductase in rat liver and kidney.

O. Sugita, S. Sassa, A. Kappas, 1988, Biochemical and biophysical research communications.

Prematurely evoked synthesis and induction of delta-aminolevulinate synthetase in neonatal liver. Evidence for metal ion repression of enzyme formation.

A. Kappas, M. Maines, 1978, The Journal of biological chemistry.

Studies on porphyrin-heme biosynthesis in organotypic cultures of chick dorsal root ganglion. I. Observations on neuronal and non-neuronal elements.

D. Bickers, W. Whetsell, S. Sassa, 1978, Journal of neuropathology and experimental neurology.

Interaction of cytochrome P-450 with antibodies raised against a solubilized P-450 preparation from hepatic microsomes.

R. Winchester, A. Kappas, F. Mitani, 1971, Molecular Pharmacology.

Effects of protein and carbohydrate content of diet on drug conjugation

A. Conney, K. Anderson, A. Kappas, 1991, Clinical pharmacology and therapeutics.

The induction of a carcinogen-metabolizing enzyme in human skin.

A. Conney, D. Bickers, A. Kappas, 1973, Transactions of the American Clinical and Climatological Association.

Synthetic metalloporphyrins: A class of compounds of pharmacological interest

A. Kappas, G. Drummond, 1985, BioEssays : news and reviews in molecular, cellular and developmental biology.

Diet and cimetidine induce comparable changes in theophylline metabolism in normal subjects

K. Anderson, A. Kappas, E. Vesell, 1991, Hepatology.

Tin(Sn+4)-diiododeuteroporphyrin; an in vitro and in vivo inhibitor of heme oxygenase with substantially reduced photoactive properties.

N. L. Greenbaum, A. Kappas, G. Drummond, 1991, The Journal of pharmacology and experimental therapeutics.

Enzymes of heme metabolism is the kidney. Regulation by trace metals which do not form heme complexes

A. Kappas, M. Maines, 1977, The Journal of experimental medicine.

Cobalt inhibition of synthesis and induction of delta-aminolevulinate synthase in liver.

A. Kappas, M. Maines, V. Janoušek, 1976, Proceedings of the National Academy of Sciences of the United States of America.

Lead poisoning from "do-it-yourself" heat guns for removing lead-based paint: Report of two cases

R. Lilis, L. Sarkozi, K. Anderson, 1981 .

Succinylacetone and delta-aminolevulinic acid dehydratase in hereditary tyrosinemia: immunochemical study of the enzyme.

S. Sassa, A. Kappas, H. Fujita, 1990, Pediatrics.

Lead and polychlorinated biphenyls: effects on heme and drug metabolism.

A. Kappas, A. Alvares, 1979, Drug metabolism reviews.

Diet and cimetidine induce comparable changes in theophylline metabolism in normal subjects

K. Anderson, A. Kappas, E. Vesell, 1991, Hepatology.

Studies in steroid metabolism. XIX. The alpha-ketosteroid excretion pattern in normal males.

C. P. Rhoads, A. Kappas, T. Gallagher, 1953, The Journal of clinical investigation.

Hyperbeta-lipoproteinemia in acute intermittent porphyria; preliminary report.

R. Lees, A. Kappas, C. Song, 1970, New England Journal of Medicine.

A comparison of the utility of Dowex resin and polybenzimidazole Aurorez resin in the determination of urinary porphobilinogen concentrations.

S. Sassa, A. Kappas, R. Galbraith, 1987, Clinica chimica acta; international journal of clinical chemistry.

Fluorometric measurement of tin-protoporphyrin in biological samples.

K. Anderson, S. Sassa, A. Kappas, 1984, Analytical Biochemistry.

Induction of hepatic delta-amino-levulinic acid synthetase by oral contraceptive steroids.

A. Kappas, P. Gillette, C. Song, 1970, The Journal of clinical endocrinology and metabolism.

The effects of acute-phase inducers and dimethyl sulphoxide on delta-aminolaevulinate synthase activity in human HepG2 hepatoma cells.

S. Sassa, A. Kappas, F. Iwasa, 1989, The Biochemical journal.

Coexpression of erythropoietin and heme oxygenase genes in Hep3B cells

S. Shibahara, N. Abraham, A. Kappas, 1993, Hepatology.

Incorporation of metalloporphyrin inhibitors of heme oxygenase into micelles and liposomes.

N. L. Greenbaum, A. Kappas, 1994, Pharmacology.

The role of inorganic metals and metalloporphyrins in the induction of haem oxygenase and heat-shock protein 70 in human hepatoma cells.

K. Mitani, S. Sassa, A. Kappas, 1993, The Biochemical journal.

DRUG‐INDUCED ALTERATIONS OF STEROID HORMONE METABOLISM IN MAN *

D. Bickers, A. Kappas, H. Bradlow, 1973, Annals of the New York Academy of Sciences.

STUDIES IN PORPHYRIA

D. Bickers, A. Kappas, L. Harber, 1977 .

Biochemical and clinical aspects of the porphyrias.

A. Kappas, R. Levere, 1968, Advances in clinical chemistry.

Selenium regulation of hepatic heme metabolism : Induction of 6-aminolevulinate synthase and heme oxygenase ( hemoproteins / heme synthesis / drug metabolism / porphyrins )

A. Kappas, M. Maines, 2022 .