N. Wortham

发表

eIF2B: recent structural and functional insights into a key regulator of translation.

C. Proud, N. Wortham, 2015, Biochemical Society transactions.

Severity of vanishing white matter disease does not correlate with deficits in eIF2B activity or the integrity of eIF2B complexes

Hua Tang, G. Scheper, C. Proud, 2011, Human mutation.

7q deletion mapping and expression profiling in uterine fibroids

L. Aaltonen, D. Arango, S. Vanharanta, 2005, Oncogene.

Evidence of increased microvessel density and activation of the hypoxia pathway in tumours from the hereditary leiomyomatosis and renal cell cancer syndrome

R. Poulsom, I. Tomlinson, G. Elia, 2005, The Journal of pathology.

The TCA cycle and tumorigenesis: the examples of fumarate hydratase and succinate dehydrogenase

I. Tomlinson, N. Wortham, P. Pollard, 2003, Annals of medicine.

Functional genetics of hereditary and sporadic uterine leiomyomas

N. Wortham, 2006 .

Aberrant expression of apoptosis proteins and ultrastructural aberrations in uterine leiomyomas from patients with hereditary leiomyomatosis and renal cell carcinoma.

I. Tomlinson, G. Elia, E. Barclay, 2006, Fertility and sterility.

Stoichiometry of the eIF2B complex is maintained by mutual stabilization of subunits.

C. Proud, N. Wortham, J. Stewart, 2016, The Biochemical journal.

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations.

J R Griffiths, R Poulsom, T. Hunt, 2005, Human molecular genetics.

Genetic and functional analyses of FH mutations in multiple cutaneous and uterine leiomyomatosis, hereditary leiomyomatosis and renal cancer, and fumarate hydratase deficiency.

N P Burrows, M Keefe, A. Rowan, 2003, Human molecular genetics.

Genomic organization and embryonic expression of igsf8, an immunoglobulin superfamily member implicated in development of the nervous system and organ epithelia

A. Copp, D. Gerrelli, P. Stanier, 2003, Molecular and Cellular Neuroscience.

Adult leydig cell tumors of the testis caused by germline fumarate hydratase mutations.

D. Berney, I. Ellis, R. Poulsom, 2006, The Journal of clinical endocrinology and metabolism.

Definition of a minimal region of deletion of chromosome 7 in uterine leiomyomas by tiling‐path microarray CGH and mutation analysis of known genes in this region

Rainer Lehtonen, Cordelia Langford, Auli Karhu, 2007, Genes, chromosomes & cancer.

Dercum's disease.

I. Tomlinson, N. Wortham, 2005, Skinmed.

A comprehensive study of chromosome 16q in invasive ductal and lobular breast carcinoma using array CGH

N. Carter, H. Fiegler, C. Collins, 2006, Oncogene.

CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability.

O. Sieber, S. Halford, I. Tomlinson, 2005, Cancer research.

Single base mutation in the fumarate hydratase gene leading to segmental cutaneous leiomyomatosis.

A. Enk, U. Jappe, N. Wortham, 2008, Acta dermato-venereologica.

Biochemical effects of mutations in the gene encoding the alpha subunit of eukaryotic initiation factor (eIF) 2B associated with Vanishing White Matter disease

C. Proud, N. Wortham, 2015, BMC Medical Genetics.

Adult-onset leukoencephalopathies with vanishing white matter with novel missense mutations in EIF2B2, EIF2B3, and EIF2B5

A. Hida, S. Aoki, T. Matsukawa, 2011, neurogenetics.

Identification of Residues That Underpin Interactions within the Eukaryotic Initiation Factor (eIF2) 2B Complex

C. Proud, N. Wortham, Xuemin Wang, 2012, The Journal of Biological Chemistry.

Analysis of the subunit organization of the eIF2B complex reveals new insights into its structure and regulation

C. Robinson, C. Proud, Y. Gordiyenko, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Analysis of the subunit organization of the eIF2B complex reveals new insights into its structure and regulation

C. Robinson, C. Proud, Y. Gordiyenko, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.