L. Korhonen

发表

Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins.

Sami Reijonen, N. Putkonen, A. Nørremølle, 2008, Experimental cell research.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

NAIP interacts with hippocalcin and protects neurons against calcium‐induced cell death through caspase‐3‐dependent and ‐independent pathways

J. Kukkonen, D. Lindholm, L. Korhonen, 2000, The EMBO journal.

XIAP decreases caspase-12 cleavage and calpain activity in spinal cord of ALS transgenic mice.

H. Wootz, D. Lindholm, L. Korhonen, 2006, Experimental cell research.

Regulation of sympathetic neuron and neuroblastoma cell death by XIAP and its association with proteasomes in neural cells

E. Jokitalo, D. Lindholm, L. Korhonen, 2003, Molecular and Cellular Neuroscience.

Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and Disease

S. Kõks, D. Lindholm, L. Korhonen, 2017, Front. Cell Dev. Biol..

Hippocalcin protects against caspase-12-induced and age-dependent neuronal degeneration

J. Kukkonen, K. Takamatsu, D. Lindholm, 2005, Molecular and Cellular Neuroscience.

Reciprocal Regulation of Very Low Density Lipoprotein Receptors (VLDLRs) in Neurons by Brain-derived Neurotrophic Factor (BDNF) and Reelin

D. Lindholm, L. Korhonen, Timofey V. Tselykh, 2013, The Journal of Biological Chemistry.

The Unfolded Protein Response and Autophagy as Drug Targets in Neuropsychiatric Disorders

D. Lindholm, L. Korhonen, Vignesh Srinivasan, 2020, Frontiers in Cellular Neuroscience.

Hepatocyte Growth Factor Activator Inhibitor-1 Is Induced by Bone Morphogenetic Proteins and Regulates Proliferation and Cell Fate of Neural Progenitor Cells

M. Hokkanen, D. Lindholm, L. Korhonen, 2013, PloS one.

Mylip makes an Idol turn into regulation of LDL receptor

D. Lindholm, L. Korhonen, B. Bornhauser, 2009, Cellular and Molecular Life Sciences.

Involvement of cyclin‐dependent kinase‐5 in the kainic acid‐mediated degeneration of glutamatergic synapses in the rat hippocampus

N. Belluardo, J. Kukkonen, N. Putkonen, 2011, The European journal of neuroscience.

Downregulation of the HERG (KCNH2) K+ channel by ceramide: evidence for ubiquitin-mediated lysosomal degradation

D. Lindholm, L. Korhonen, K. Törnquist, 2005, Journal of Cell Science.

Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1a

Sami Reijonen, D. Lindholm, L. Korhonen, 2014 .

Fibroblast Growth Factor-21 (FGF21) Regulates Low-density Lipoprotein Receptor (LDLR) Levels in Cells via the E3-ubiquitin Ligase Mylip/Idol and the Canopy2 (Cnpy2)/Mylip-interacting Saposin-like Protein (Msap)*

V. Olkkonen, N. Zelcer, D. Lindholm, 2012, The Journal of Biological Chemistry.

Fibroblast Growth Factor-21 (FGF21) Regulates Low-density Lipoprotein Receptor (LDLR) Levels in Cells via the E3-ubiquitin Ligase Mylip/Idol and the Canopy2

V. Olkkonen, N. Zelcer, D. Lindholm, 2012 .

Fibroblast growth factor-21 enhances mitochondrial functions and increases the activity of PGC-1 alpha in human dopaminergic neurons via Sirtuin-1 Mäkelä

N. Belluardo, G. Mudó, F. Maiorana, 2022 .

Peroxisome proliferator-activated receptor-γ (PPARγ) agonist is neuroprotective and stimulates PGC-1α expression and CREB phosphorylation in human dopaminergic neurons

J. Kukkonen, D. Lindholm, L. Korhonen, 2016, Neuropharmacology.

PGC-1α: a master gene that is hard to master

N. Belluardo, D. Lindholm, L. Korhonen, 2012, Cellular and Molecular Life Sciences.

Neuronal expression of the ERM-like protein MIR in rat brain and its localization to human chromosome 6.

D. Lindholm, L. Korhonen, B. Bornhauser, 2000, Biochemical and biophysical research communications.

Expression of c‐Met in developing rat hippocampus: evidence for HGF as a neurotrophic factor for calbindin D‐expressing neurons

E. Castrén, P. Schirmacher, N. Takei, 2000, The European journal of neuroscience.

Orexin/hypocretin receptor chimaeras reveal structural features important for orexin peptide distinction

Pauli M Turunen, R. Ra, J. Kukkonen, 2011, FEBS letters.

OX1 orexin receptors activate extracellular signal-regulated kinase in Chinese hamster ovary cells via multiple mechanisms: the role of Ca2+ influx in OX1 receptor signaling.

H. Haas, J. Kukkonen, L. Korhonen, 2006, Molecular endocrinology.

Pituitary adenylate cyclase‐activating polypeptide promotes the survival of basal forebrain cholinergic neurons in vitro and in vivo: comparison with effects of nerve growth factor

M. Sofroniew, H. Hatanaka, G. Schütz, 2000, The European journal of neuroscience.

Bruce/apollon promotes hippocampal neuron survival and is downregulated by kainic acid.

N. Belluardo, D. Lindholm, L. Korhonen, 2005, Biochemical and biophysical research communications.

Amyotrophic lateral sclerosis: evidence for intact hepatocyte growth factor/met signalling axis.

P. Schirmacher, A. Wallin, S. Aquilonius, 2001, Cytokine.

NF‐κB‐dependent regulation of brain‐derived neurotrophic factor in hippocampal neurons by X‐linked inhibitor of apoptosis protein

K. Blomgren, J. Kukkonen, D. Lindholm, 2009, The European journal of neuroscience.

Endoplasmic Reticulum Stress Inhibition Protects against Excitotoxic Neuronal Injury in the Rat Brain

N. Belluardo, G. Mudó, L. Khiroug, 2007, The Journal of Neuroscience.

Differential regulation of X-chromosome-linked inhibitor of apoptosis protein (XIAP) and caspase-3 by NMDA in developing hippocampal neurons; involvement of the mitochondrial pathway in NMDA-mediated neuronal survival.

D. Lindholm, L. Korhonen, H. Steen, 2004, Experimental cell research.

Neuronal apoptosis inhibitory protein: Structural requirements for hippocalcin binding and effects on survival of NGF-dependent sympathetic neurons.

J. Kukkonen, D. Lindholm, L. Korhonen, 2002, Biochimica et biophysica acta.

Neurotrophic Factors in Cerebrospinal Fluid and Serum of Patients With Rett Syndrome

D. Lindholm, L. Korhonen, R. Vanhala, 1998, Journal of child neurology.

Estrogen-Receptor-Dependent Regulation of Neural Stem Cell Proliferation and Differentiation

D. Lindholm, L. Korhonen, K. Brännvall, 2002, Molecular and Cellular Neuroscience.

Increase in Bcl‐2 phosphorylation and reduced levels of BH3‐only Bcl‐2 family proteins in kainic acid‐mediated neuronal death in the rat brain

N. Belluardo, G. Mudó, D. Lindholm, 2003, The European journal of neuroscience.

Anti-Apoptotic Proteins in Nerve Cell Survival and Neurodegeneration BY LAURA KORHONEN

L. Korhonen, M. G., I. Korhonen, 2002 .

The E3 Ubiquitin Ligase IDOL Induces the Degradation of the Low Density Lipoprotein Receptor Family Members VLDLR and ApoER2*

Peter Tontonoz, Vincenzo Sorrentino, T. V. van Berkel, 2010, The Journal of Biological Chemistry.

Irradiation-induced progenitor cell death in the developing brain is resistant to erythropoietin treatment and caspase inhibition

K. Blomgren, T. Björk-Eriksson, M. Leist, 2004, Cell Death and Differentiation.

ER stress and neurodegenerative diseases

H. Wootz, D. Lindholm, L. Korhonen, 2006, Cell Death and Differentiation.

X chromosome‐linked inhibitor of apoptosis protein reduces oxidative stress after cerebral irradiation or hypoxia‐ischemia through up‐regulation of mitochondrial antioxidants

Changlian Zhu, K. Blomgren, P. Eriksson, 2007, The European journal of neuroscience.

Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease

N. Belluardo, G. Mudó, D. Lindholm, 2012, Cellular and Molecular Life Sciences.

X-linked inhibitor of apoptosis protein increases mitochondrial antioxidants through NF-kappaB activation.

K. Blomgren, D. Lindholm, L. Korhonen, 2007, Biochemical and biophysical research communications.

Mitochondrial proteins in neuronal degeneration.

D. Lindholm, L. Korhonen, Dan Lindholm, 2004, Biochemical and biophysical research communications.

GADD34 mediates cytoprotective autophagy in mutant huntingtin expressing cells via the mTOR pathway.

Sami Reijonen, D. Lindholm, L. Korhonen, 2012, Experimental cell research.

Glucocorticoid Hormones Decrease Proliferation of Embryonic Neural Stem Cells through Ubiquitin-Mediated Degradation of Cyclin D1

M. Sundberg, D. Lindholm, L. Korhonen, 2006, The Journal of Neuroscience.

Transgenic mice overexpressing XIAP in neurons show better outcome after transient cerebral ischemia

D. Lindholm, L. Korhonen, R. Martinez, 2003, Molecular and Cellular Neuroscience.

Neuronal expression and regulation of rat inhibitor of apoptosis protein‐2 by kainic acid in the rat brain

N. Belluardo, G. Mudó, D. Lindholm, 2002, The European journal of neuroscience.

Regulation of X-Chromosome-Linked Inhibitor of Apoptosis Protein in Kainic Acid-Induced Neuronal Death in the Rat Hippocampus

N. Belluardo, D. Lindholm, L. Korhonen, 2001, Molecular and Cellular Neuroscience.

Tumor suppressor gene BRCA‐1 is expressed by embryonic and adult neural stem cells and involved in cell proliferation

D. Lindholm, L. Korhonen, K. Brännvall, 2003, Journal of neuroscience research.

Dexamethasone regulates expression of BRUCE/Apollon and the proliferation of neural progenitor cells

M. Naito, D. Lindholm, L. Korhonen, 2009, FEBS letters.

19‐Nortestosterone influences neural stem cell proliferation and neurogenesis in the rat brain

N. Bogdanovic, D. Lindholm, L. Korhonen, 2005, The European journal of neuroscience.

Cystatin-B is expressed by neural stem cells and by differentiated neurons and astrocytes.

D. Lindholm, L. Korhonen, A. Lehesjoki, 2003, Biochemical and biophysical research communications.

Nerve Growth Factor Induces Process Formation in Meningeal Cells: Implications for Scar Formation in the Injured CNS

S. Cullheim, M. Risling, J. Frisén, 1998, The Journal of Neuroscience.

Brain derived neurotrophic factor is increased in cerebrospinal fluid of children suffering from asphyxia

H. Nawa, D. Lindholm, L. Korhonen, 1998, Neuroscience Letters.

X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia–ischemia

Changlian Zhu, K. Blomgren, Xiaoyang Wang, 2004, Neurobiology of Disease.

PGC-1α Signaling Increases GABA(A) Receptor Subunit α2 Expression, GABAergic Neurotransmission and Anxiety-Like Behavior in Mice

M. Lalowski, D. Lindholm, L. Korhonen, 2021, Frontiers in Molecular Neuroscience.

Interferon-γ Produced by Microglia and the Neuropeptide PACAP Have Opposite Effects on the Viability of Neural Progenitor Cells

D. Lindholm, L. Korhonen, R. Koivuniemi, 2010, PloS one.

Proteasome Role in Neurodegeneration

N. Putkonen, D. Lindholm, L. Korhonen, 2009 .

Downregulation of NF-κB signaling by mutant huntingtin proteins induces oxidative stress and cell death

N. Takei, J. Kukkonen, Sami Reijonen, 2010, Cellular and Molecular Life Sciences.

Bcl‐2 Regulates the Levels of the Cysteine Proteases ICH and CPP32/Yama in Human Neuronal Precursor Cells

D. Lindholm, L. Korhonen, P. Olsson, 1997, The European journal of neuroscience.

Sphingolipids as Modulators of SARS-CoV-2 Infection

L. Korhonen, K. Törnquist, M. Y. Asghar, 2021, Frontiers in Cell and Developmental Biology.

Fibroblast growth factor-21 enhances mitochondrial functions and increases the activity of PGC-1α in human dopaminergic neurons via Sirtuin-1

N. Belluardo, G. Mudó, F. Maiorana, 2014, SpringerPlus.

Expression of X-chromosome linked inhibitor of apoptosis protein in mature purkinje cells and in retinal bipolar cells in transgenic mice induces neurodegeneration

G. Fisone, C. Sotelo, E. Jokitalo, 2008, Neuroscience.

Caspase-12 cleavage and increased oxidative stress during motoneuron degeneration in transgenic mouse model of ALS.

H. Wootz, D. Lindholm, L. Korhonen, 2004, Biochemical and biophysical research communications.

Nerve growth factor (NGF) and pro‐NGF increase low‐density lipoprotein (LDL) receptors in neuronal cells partly by different mechanisms: role of LDL in neurite outgrowth

M. Jauhiainen, D. Lindholm, L. Korhonen, 2016, Journal of neurochemistry.

Estrogen receptor-dependent regulation of sensory neuron survival in developing dorsal root ganglion.

D. Lindholm, L. Korhonen, S. Andersson, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Sigma-1 receptor agonist PRE084 is protective against mutant huntingtin-induced cell degeneration: involvement of calpastatin and the NF-κB pathway

T. Ho, D. Lindholm, L. Korhonen, 2013, Cell Death and Disease.

PACAP and Neural Progenitor Cells

D. Lindholm, L. Korhonen, Johanna Mäkelä, 2016 .

Sigma-1 receptor agonist PRE 084 is protective against mutant huntingtin-induced cell degeneration : involvement of calpastatin and the NF-kappa B pathway

D. Lindholm, L. Korhonen, T. Ho, 2022 .

Peroxisome proliferator‐activated receptor‐γ coactivator‐1α mediates neuroprotection against excitotoxic brain injury in transgenic mice: role of mitochondria and X‐linked inhibitor of apoptosis protein

N. Belluardo, M. Lalowski, G. Mudó, 2016, The European journal of neuroscience.

Resveratrol reduces oxidative stress and cell death and increases mitochondrial antioxidants and XIAP in PC6.3-cells

N. Belluardo, G. Mudó, D. Lindholm, 2011, Neuroscience Letters.

Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1α.

Sami Reijonen, D. Lindholm, L. Korhonen, 2014, Human molecular genetics.

Involvement of estrogen receptors in the resveratrol-mediated increase in dopamine transporter in human dopaminergic neurons and in striatum of female mice

N. Belluardo, G. Mudó, D. Lindholm, 2012, Neuropharmacology.

MIR Is a Novel ERM-like Protein That Interacts with Myosin Regulatory Light Chain and Inhibits Neurite Outgrowth*

D. Lindholm, L. Korhonen, P. Olsson, 1999, The Journal of Biological Chemistry.

p75 Neurotrophin Receptor Signaling Activates Sterol Regulatory Element-binding Protein-2 in Hepatocyte Cells via p38 Mitogen-activated Protein Kinase and Caspase-3*

J. Kukkonen, D. Lindholm, L. Korhonen, 2016, The Journal of Biological Chemistry.

Altered distribution and levels of cathepsinD and cystatins in amyotrophic lateral sclerosis transgenic mice: Possible roles in motor neuron survival

H. Wootz, D. Lindholm, L. Korhonen, 2006, Neuroscience.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Partial resistance to malonate‐induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length

O. Hansson, P. Brundin, G. Bates, 2001, Journal of neurochemistry.

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

PGC-1α: a master gene that is hard to master

N. Belluardo, D. Lindholm, L. Korhonen, 2012, Cellular and Molecular Life Sciences.

Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease

Petteri Piepponen, Johanna Mäkelä, Alessandra Bonomo, 2011, Cellular and Molecular Life Sciences.

The ubiquitin proteasome system in synaptic and axonal degeneration

D. Lindholm, L. Korhonen, 2004, The Journal of cell biology.

Interleukin-6 and Interleukin-1 receptor antagonist in cerebrospinal fluid from patients with recent tonic–clonic seizures

A. Miettinen, J. Peltola, D. Lindholm, 2000, Epilepsy Research.

Anti-apoptotic proteins in nerve cell survival and neurodegeneration.

L. Korhonen, 2002 .

Regulation of HERG (KCNH2) potassium channel surface expression by diacylglycerol

D. Lindholm, L. Korhonen, K. Törnquist, 2009, Cellular and Molecular Life Sciences.

Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration : involvement of the proteasome and ER stress-activated kinase IRE 1 a

Sami Reijonen, D. Lindholm, L. Korhonen, 2014 .

Nerve growth factor in serum of children with systemic lupus erythematosus is correlated with disease activity.

K. Aalto, D. Lindholm, L. Korhonen, 2002, Cytokine.