Piotr F. J. Lipiński

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In Vivo, In Vitro and In Silico Studies of the Hybrid Compound AA3266, an Opioid Agonist/NK1R Antagonist with Selective Cytotoxicity

A. Misicka, P. Kosson, Joanna Matalińska, 2020, International journal of molecular sciences.

On splitting of the NICS(1) magnetic aromaticity index

Piotr F. J. Lipiński, J. Dobrowolski, 2016 .

Structural studies on radiopharmaceutical DOTA-minigastrin analogue (CP04) complexes and their interaction with CCK2 receptor

R. Mikołajczak, P. Garnuszek, M. Maurin, 2018, EJNMMI Research.

Substituent effect in theoretical ROA spectra

Piotr F. J. Lipiński, J. Dobrowolski, 2014 .

Fentanyl Structure as a Scaffold for Opioid/Non-Opioid Multitarget Analgesics

Joanna Matalińska, Piotr F. J. Lipiński, 2022, International journal of molecular sciences.

Synthesis, Pharmacological Evaluation, and Computational Studies of Cyclic Opioid Peptidomimetics Containing β3-Lysine

A. Janecka, Piotr F. J. Lipiński, A. Kluczyk, 2021, Molecules.

Antinociceptive and Cytotoxic Activity of Opioid Peptides with Hydrazone and Hydrazide Moieties at the C-Terminus

A. Misicka, P. Kosson, Joanna Matalińska, 2020, Molecules.

Fentanyl Family at the Mu-Opioid Receptor: Uniform Assessment of Binding and Computational Analysis

A. Misicka, P. Kosson, Joanna Matalińska, 2019, Molecules.

The FMO analysis of the molecular interaction of fentanyl derivatives with the μ-opioid receptor

Piotr F. J. Lipiński, J. Dobrowolski, J. Sadlej, 2017, Chemical Papers.

Conformational latitude – activity relationship of KPPR tetrapeptide analogues toward their ability to inhibit binding of vascular endothelial growth factor 165 to neuropilin‐1

A. Misicka, Piotr F. J. Lipiński, G. Perret, 2017, Journal of peptide science : an official publication of the European Peptide Society.

Structure-activity relationship study of tetrapeptide inhibitors of the Vascular Endothelial Growth Factor A binding to Neuropilin-1

A. Misicka, Piotr F. J. Lipiński, G. Perret, 2017, Peptides.

Branched pentapeptides as potent inhibitors of the vascular endothelial growth factor 165 binding to Neuropilin-1: Design, synthesis and biological activity.

A. Misicka, Piotr F. J. Lipiński, G. Perret, 2018, European journal of medicinal chemistry.

Triazolopeptides Inhibiting the Interaction between Neuropilin-1 and Vascular Endothelial Growth Factor-165

A. Misicka, Piotr F. J. Lipiński, G. Perret, 2019, Molecules.

Conformation of six fentanyls revisited

Piotr F. J. Lipiński, J. Dobrowolski, J. Sadlej, 2016 .

On Raman optical activity sign-switching between the ground and excited states leading to an unusual resonance ROA induced chirality

Piotr F. J. Lipiński, M. Barańska, J. E. Rode, 2020, Chemical science.

Evaluation of Receptor Affinity, Analgesic Activity and Cytotoxicity of a Hybrid Peptide, AWL3020

P. Kosson, Joanna Matalińska, Piotr F. J. Lipiński, 2020, International Journal of Peptide Research and Therapeutics.

Hydrazone Linker as a Useful Tool for Preparing Chimeric Peptide/Nonpeptide Bifunctional Compounds.

A. Misicka, P. Kosson, Piotr F. J. Lipiński, 2017, ACS medicinal chemistry letters.

Correcting a widespread error: Neuroprotectant N-acetyl-L-tryptophan does not bind to the neurokinin-1 receptor

Joanna Matalińska, Piotr F. J. Lipiński, 2022, Molecular and Cellular Neuroscience.

Evaluation of Receptor Affinity, Analgesic Activity and Cytotoxicity of a Hybrid Peptide, AWL3020

P. Kosson, Joanna Matalińska, Piotr F. J. Lipiński, 2020, International Journal of Peptide Research and Therapeutics.

An excursion into secondary pharmacology of fentanyls with potential implications for drug design: σ1 receptor

A. Misicka, P. Kosson, Piotr F. J. Lipiński, 2022, Treatments, Mechanisms, and Adverse Reactions of Anesthetics and Analgesics.

Affinity of fentanyl and its derivatives for the σ1-receptor.

A. Misicka, P. Kosson, Piotr F. J. Lipiński, 2019, MedChemComm.

Bifunctional Opioid/Melanocortin Peptidomimetics for Use in Neuropathic Pain: Variation in the Type and Length of the Linker Connecting the Two Pharmacophores

M. Godlewska, A. Misicka, Joanna Matalińska, 2022, International journal of molecular sciences.

α-Amino Acids In Water: A Review Of VCD And ROA Spectra

Piotr F. J. Lipiński, J. E. Rode, J. Dobrowolski, 2014 .

The solid state VCD of a novel N-acylhydrazone trifluoroacetate.

A. Misicka, Joanna Matalińska, Piotr F. J. Lipiński, 2021, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

Pharmacological Profile and Molecular Modeling of Cyclic Opioid Analogues Incorporating Various Phenylalanine Derivatives

A. Janecka, Piotr F. J. Lipiński, A. Kluczyk, 2020, ChemMedChem.

SCRAMBLE’N’GAMBLE: a tool for fast and facile generation of random data for statistical evaluation of QSAR models

Piotr F J Lipiński, Przemysław Szurmak, Piotr F. J. Lipiński, 2017, Chemical Papers.

Molecular dynamics of fentanyl bound to μ-opioid receptor

Piotr F. J. Lipiński, J. Dobrowolski, J. Sadlej, 2019, Journal of Molecular Modeling.

Design, synthesis and in vitro biological evaluation of a small cyclic peptide as inhibitor of vascular endothelial growth factor binding to neuropilin-1.

A. Misicka, Piotr F. J. Lipiński, K. Grabowska, 2016, Bioorganic & medicinal chemistry letters.

Radiochemical Synthesis and Evaluation of Novel Radioconjugates of Neurokinin 1 Receptor Antagonist Aprepitant Dedicated for NK1R-Positive Tumors

A. Misicka, Joanna Matalińska, Piotr F. J. Lipiński, 2020, Molecules.

Antiproliferative effects of [D-Pro2, D-Trp7,9]-Substance P and aprepitant on several cancer cell lines and their selectivity in comparison to normal cells.

A. Misicka, Joanna Matalińska, Piotr F. J. Lipiński, 2020, Folia neuropathologica.

Structural Insights into σ1 Receptor Interactions with Opioid Ligands by Molecular Dynamics Simulations

Mateusz Kurcinski, Piotr F. J. Lipiński, J. Dobrowolski, 2018, Molecules.

The influence of the position of a chiral substituent on undecathiophene chain. A DFT study

Michal Jamróz, Piotr F. J. Lipiński, J. E. Rode, 2018, Synthetic Metals.

Chirality Measures of α-Amino Acids

Piotr Lipinski, Michal Jamróz, Jan Cz. Dobrowolski, 2012, J. Chem. Inf. Model..

Gαi-derived peptide binds the µ-opioid receptor

A. Bojarski, A. Misicka, P. Kosson, 2019, bioRxiv.

Enantioselective sensing of (S)-Thalidomide in blood plasma with a chiral naphthalene diimide derivative.

I. Grudzinski, Piotr F. J. Lipiński, A. Nowicka, 2020, Biosensors & bioelectronics.

Structure-activity relationship study of a small cyclic peptide H-c[Lys-Pro-Glu]-Arg-OH: a potent inhibitor of Vascular Endothelial Growth Factor interaction with Neuropilin-1.

A. Misicka, Piotr F. J. Lipiński, K. Grabowska, 2017, Bioorganic & medicinal chemistry.

Novel NK1R-Targeted 68Ga-/177Lu-Radioconjugates with Potential Application against Glioblastoma Multiforme: Preliminary Exploration of Structure–Activity Relationships

A. Misicka, Joanna Matalińska, Piotr F. J. Lipiński, 2022, International journal of molecular sciences.

β2-Homo-Amino Acid Scan of µ-Selective Opioid Tetrapeptide TAPP

A. Misicka, P. Kosson, Piotr F. J. Lipiński, 2020, Molecules.

The analgesic hybrid of dermorphin/substance P and analog of enkephalin improve wound healing in streptozotocin‐induced diabetic rats

P. Kosson, Joanna Matalińska, Piotr F. J. Lipiński, 2020, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

PSMA-D4 Radioligand for Targeted Therapy of Prostate Cancer: Synthesis, Characteristics and Preliminary Assessment of Biological Properties

R. Mikołajczak, P. Garnuszek, M. Maurin, 2021, International journal of molecular sciences.

Design, synthesis and in vitro biological evaluation of a small cyclic peptide as inhibitor of vascular endothelial growth factor binding to neuropilin-1.

A. Misicka, Piotr F. J. Lipiński, K. Grabowska, 2016, Bioorganic & medicinal chemistry letters.

Triazolopeptides Inhibiting the Interaction between Neuropilin-1 and Vascular Endothelial Growth Factor-165

A. Misicka, Piotr F. J. Lipiński, B. Wileńska, 2019, Molecules.

In Vitro Biological Evaluation of Aprepitant Based 177Lu-Radioconjugates

A. Misicka, Joanna Matalińska, Piotr F. J. Lipiński, 2022, Pharmaceutics.

The influence of a synthetic growth hormone‐releasing hormone analogue G11 and opioid peptide biphalin on selected fibroblasts parameters relevant to wound healing

A. Misicka, Piotr F. J. Lipiński, Patrycja Redkiewicz, 2023, Journal of peptide science : an official publication of the European Peptide Society.

Virtual screening for small molecular non-covalent binders of the SARS-CoV-2 main protease

P. Garnuszek, Piotr F. J. Lipiński, Przemyslaw Szurmak, 2021, Archives of medical science : AMS.

Structural Analysis of 3,5-Bistrifluoromethylhydrocinnamic Acid

Piotr F. J. Lipiński, Krzysztof Łyczko, 2024, Crystals.

Peptidomimetic inhibitors of the VEGF-A165/NRP-1 complex obtained by modification of the C-terminal arginine

Piotr F. J. Lipiński, Patrycja Redkiewicz, Dagmara Tymecka, 2024, Amino acids.

Applications of biaryl cyclization in the synthesis of cyclic enkephalin analogs with a highly restricted flexibility

Joanna Matalińska, Piotr F. J. Lipiński, Mariusz Jaremko, 2024, Amino acids.

Thiolated Chiral Naphthalene Diimide Derivatives as Effective Selectors of the β‐Blocker Atenolol Enantiomers

I. Grudzinski, Piotr F. J. Lipiński, J. E. Rode, 2024, Advanced Functional Materials.

Substituent Effect in the First Excited Singlet State of Monosubstituted Benzenes.

Piotr F. J. Lipiński, J. Dobrowolski, G. Karpińska, 2018, The journal of physical chemistry. A.

Docking is not enough: 17-trifluoromethylphenyl trinor PGF2α is only a very weak ligand of neurokinin-1 receptor.

Joanna Matalińska, Piotr F. J. Lipiński, 2022, Experimental and molecular pathology.